CN1247215C - Medicine for treating mouth mucous ulcer - Google Patents
Medicine for treating mouth mucous ulcer Download PDFInfo
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- CN1247215C CN1247215C CN 03113217 CN03113217A CN1247215C CN 1247215 C CN1247215 C CN 1247215C CN 03113217 CN03113217 CN 03113217 CN 03113217 A CN03113217 A CN 03113217A CN 1247215 C CN1247215 C CN 1247215C
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- medicament
- medicine
- ulcer
- mouth mucous
- vitamin
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- Medicines Containing Plant Substances (AREA)
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Abstract
The present invention provides a medicament for quickly treating mouth mucous ulcers, and a preparation method of the medicament. Vitamin C is used as main raw materials; the concentrated extract of honeysuckle is used as auxiliary materials; the main raw materials and the auxiliary materials are prepared into tablets, powder or paste. The medicament is directly attached to or laid on the ulcer surfaces for one to two times in a day. The medicament can rapidly promote the healing of the ulcer surfaces, with good curative effect on relieving pains caused by mouth mucous ulcers, and can dissolve the neohymen of the ulcer surfaces. The medicament has the functions for clearing away heat and toxic materials, resisting inflammation and killing bacteria, and rapidly cures the mouth mucous ulcers. The medicament for treating mouth mucous ulcers has the advantages of low toxicity, high efficiency and quickness.
Description
Technical field
The present invention relates to a kind of external and attach medicine and production method thereof, specifically a kind of medicine and production method thereof for the treatment of stomatocace.
Background technology
At present clinically, treatments such as the many employings of treatment stomatocace compound vitamin B for oral administration and corticosteroids medicine; Also have part to adopt external buccal tablet medicine to treat, wait influence but be subject to saliva of buccal cavity secretion dilution, action time is short, and the medication cycle is longer, lacks specificity, and toxic and side effects is big, and is relatively poor to the pain relief effect that stomatocace causes, the ulcer surface healing is slow.
Summary of the invention
The objective of the invention is to invent a kind of treatment stomatocace attaching medicine can be in the oral cavity, and the pseudomembrane of dissolving ulcer surface promotes the healing of ulcer surface, and drug treating time is long, and toxicity is minimum, safely and fast, clinical effectiveness is good, has overcome the deficiency of existing medicine.
The object of the present invention is to provide a kind of preparation method that stomatocace attaches medicine for the treatment of.
The invention provides a kind of treatment stomatocace and attach medicine for being primary raw material with vitamin C 30-90 part, with Flos Lonicerae concentrated extract 5-50 part, starch 10-40 part, dextrin 25-40 part are that adjuvant is made.
The parts by weight proportioning of every kind of composition also can be:
Vitamin C 30-90 part
Flos Lonicerae concentrated extract 5-50 part
Starch 10-40 part
Dextrin 25-40 part
Tartaric acid 0.5-1.5 part
Alcohol 95 % is an amount of
Magnesium stearate 1-3 part
Process for preparing medicine of the present invention is as follows:
The preparation of A, Flos Lonicerae concentrated extract mixture: Flos Lonicerae is screened, remove impurity, leaf and stalk, Flos Lonicerae adds 15 times of water gagings and decocted 1 hour, filter, medicinal residues add 10 times of water gagings again and decoct half an hour, filter, and the 4-5 that merges decoction liquor and be concentrated into the medical material amount doubly, add 20% lime cream and transfer PH to 12, leaching precipitate, precipitate add 2 times of amount ethanol suspendibles, transfer PH to 3-4 with 50% sulphuric acid, fully stir, filter, filtrate with in 40% sodium hydroxide solution and PH be 6.5-7.0, filtration, reclaim ethanol, concentrate after drying.Selected more in addition 1/10 amount Flos Lonicerae, crushed after being dried is crossed 120 mesh sieves; Mix with gained Flos Lonicerae concentrated extract, standby.
The preparation of B, tablet:, put mixing in the electronic mixer of rustless steel with vitamin C, Flos Lonicerae concentrated extract, starch, dextrin.Tartaric acid is dissolved in 95% ethanol simultaneously, once add in the Vitamin C mixture powder, mix homogeneously, make soft material, once make the wet grain of 20-40 order by 20 order nylon mesh, put and use 60-70 ℃ of drying in the drying baker, dry granular is by 14 mesh sieves, add the magnesium stearate mixing, press dry according to a conventional method.
C, medicine of the present invention also can be made into powder, powder and unguentum: its production method is identical with the method for producing other same preparation.
The tablet that the present invention makes, powder, powder and unguentum.Have the pseudomembrane on the dissolving ulcer surface, promote to alleviate the pain that ulcer causes, promote the rapid healing of ulcer surface; And have heat-clearing and toxic substances removing, the antiinflammatory bactericidal action, help vitamin C in the part abundant Absorption.At first blot the moisture content at ulcer surface position with cotton balls, directly card is attached or be attached on the stomatocace face by area size shop, every night bedtime medication once, also can by situation every day for several times.And the drying of maintenance ulcer surface, the medicine retention time is more than 3 hours.Ulcer surface healing effective percentage reached more than 95% after ulcer surface healing effective percentage reached 83.8%, 2 administration after 1 administration.
The specific embodiment
Below in conjunction with embodiment the present invention is further described.
Embodiment
A kind of medicine and preparation method for the treatment of stomatocace, the parts by weight proportioning of every kind of composition is:
90 parts of vitamin Cs
20 parts of Flos Lonicerae concentrated extracts
25 parts of starch
35 parts in dextrin
1.0 parts in tartaric acid
Alcohol 95 % is an amount of
2 parts of magnesium stearate
Process for preparing medicine of the present invention is as follows:
The preparation of A, Flos Lonicerae concentrated extract mixture: Flos Lonicerae is screened, remove impurity, leaf and stalk, Flos Lonicerae adds 15 times of water gagings and decocted 1 hour, filter, medicinal residues add 10 times of water gagings again and decoct half an hour, filter, and merge decoction liquor and are concentrated into 4 times of medical material amount, add 20% lime cream and transfer PH to 12, leaching precipitate, precipitate add 2 times of amount ethanol suspendibles, transfer PH to 3-4 with 50% sulphuric acid, fully stir, filter, it is 6.5-7.0 that filtrate is neutralized to PH with 40% sodium hydroxide solution, filters, reclaim ethanol, concentrate after drying.Selected more in addition 1/10 amount Flos Lonicerae, crushed after being dried is crossed 120 mesh sieves; Mix with gained Flos Lonicerae concentrated extract, standby.
The preparation of B, tablet:, put mixing in the electronic mixer of rustless steel with vitamin C, Flos Lonicerae concentrated extract, starch, dextrin.Tartaric acid is dissolved in 95% ethanol simultaneously, once add in the Vitamin C mixture powder, mix homogeneously, make soft material, once make the wet grain of 20-40 order by 20 order nylon mesh, put and use 60-70 ℃ of drying in the drying baker, dry granular is by 14 mesh sieves, add the magnesium stearate mixing, press dry according to a conventional method.
Claims (1)
1, a kind of medicine for the treatment of stomatocace, it is characterized by with vitamin C 30-90 part is primary raw material, with Flos Lonicerae concentrated extract 5-50 part, starch 10-40 part, dextrin 25-40 part are that adjuvant is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03113217 CN1247215C (en) | 2003-04-14 | 2003-04-14 | Medicine for treating mouth mucous ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03113217 CN1247215C (en) | 2003-04-14 | 2003-04-14 | Medicine for treating mouth mucous ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1537563A CN1537563A (en) | 2004-10-20 |
| CN1247215C true CN1247215C (en) | 2006-03-29 |
Family
ID=34320009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03113217 Expired - Fee Related CN1247215C (en) | 2003-04-14 | 2003-04-14 | Medicine for treating mouth mucous ulcer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1247215C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405681B (en) * | 2012-03-31 | 2015-04-15 | 赵艳蕾 | Preparation method of lozenge for treating oral ulcer |
-
2003
- 2003-04-14 CN CN 03113217 patent/CN1247215C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1537563A (en) | 2004-10-20 |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |