CN1537563A - Medicine for treating mouth mucous ulcer - Google Patents
Medicine for treating mouth mucous ulcer Download PDFInfo
- Publication number
- CN1537563A CN1537563A CNA031132170A CN03113217A CN1537563A CN 1537563 A CN1537563 A CN 1537563A CN A031132170 A CNA031132170 A CN A031132170A CN 03113217 A CN03113217 A CN 03113217A CN 1537563 A CN1537563 A CN 1537563A
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- CN
- China
- Prior art keywords
- medicine
- flos lonicerae
- ulcer
- vitamin
- stomatocace
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
A medicine in the form of tablet, powder, or ointment for treating mouth mucosa ulcer is prepared from VC and concentrated extract of honeysuckle flower. It can be directly applied onto the ulcerative position. Its advantage are high curative effect, low posion and quickly taking its effect.
Description
Affiliated technical field the present invention relates to a kind of external and attaches medicine and production method thereof, a kind of specifically medicine and production method thereof for the treatment of stomatocace.
Background technology is treated treatments such as the many employings of stomatocace compound vitamin B for oral administration and corticosteroids medicine at present clinically; Also have part to adopt external buccal tablet medicine to treat, wait influence but be subject to saliva of buccal cavity secretion dilution, action time is short, and the medication cycle is longer, lacks specificity, and toxic and side effects is big, and is relatively poor to the pain relief effect that stomatocace causes, the ulcer surface healing is slow.
Summary of the invention the objective of the invention is to invent a kind of treatment stomatocace attaching medicine can be in the oral cavity, and the pseudomembrane of dissolving ulcer surface promotes the healing of ulcer surface, and drug treating time is long, and toxicity is minimum, safely and fast, clinical effectiveness is good, has overcome the deficiency of existing medicine.
The object of the present invention is to provide a kind of preparation method that stomatocace attaches medicine for the treatment of.
The invention provides a kind of treatment stomatocace attaching medicine Main Ingredients and Appearance and contain vitamin c, Flos Lonicerae concentrated extract, starch, dextrin.
The parts by weight proportioning of every kind of composition is
Vitamin C 30-90 part
Flos Lonicerae concentrated extract 5-50 part
Starch 10-40 part
Dextrin 25-40 part
Tartaric acid 0.5-1.5 part
Ethanol 50% is an amount of
Magnesium stearate 1-3 part
Process for preparing medicine of the present invention is as follows:
A. the preparation of Flos Lonicerae concentrated extract mixture: Flos Lonicerae is screened, remove impurity, leaf and stalk, Flos Lonicerae adds 15 times of water gagings and decocted 1 hour, filter, medicinal residues add 10 times of water gagings again and decoct half an hour, filter, and merge 4-5 times that fries in shallow oil small piece of land surrounded by water liquid and be concentrated into the medical material amount, add 20% lime cream and transfer PH to 12, leaching precipitate, precipitate add 2 times of amount ethanol suspendibles, transfer PH to 3-4 with 50% sulphuric acid, fully stir, filter, it is 6.5-7.0 that filtrate is neutralized to PH with 40% sodium hydroxide solution, filters, reclaim ethanol, concentrate after drying.Selected more in addition 1/10 amount Flos Lonicerae, crushed after being dried is crossed 120 mesh sieves; Mix with gained Flos Lonicerae concentrated extract, standby.
B. the preparation of tablet:, put mixing in the electronic mixer of rustless steel with vitamin C, Flos Lonicerae concentrated extract mixture, starch, dextrin.Tartaric acid is dissolved in 95% ethanol simultaneously, once add in the mix powder of vitamin, mix homogeneously, make soft material, once make the wet grain of 20-40 order by 20 order nylon mesh, put and use 60-70 ℃ of drying in the drying baker, dry granular is by 14 mesh sieves, add the magnesium stearate mixing, according to a conventional method tabletting.
C. medicine of the present invention also can be made into powder, powder and unguentum: its production method is identical with the method for producing other same preparation.
The tablet that the present invention makes, powder, powder and unguentum.Have the pseudomembrane on the dissolving ulcer surface, promote to alleviate the pain that ulcer causes, promote the rapid healing of ulcer surface; And have heat-clearing and toxic substances removing, the antiinflammatory bactericidal action, help vitamin C in the part abundant Absorption.At first blot the moisture content at ulcer surface position with cotton balls, directly attach or be attached on the stomatocace face by area size shop, bedtime medication once also can be by situation several every day every night.And the drying of maintenance ulcer surface, the medicine retention time is more than 3 hours.Ulcer surface healing effective percentage reached more than 95% after ulcer surface healing effective percentage reached 83.8%, 2 administration after 1 administration.
Embodiment
A kind of medicine and preparation method for the treatment of stomatocace
The parts by weight proportioning of every kind of composition is
90 parts of vitamin Cs
20 parts of Flos Lonicerae concentrated extracts
25 parts of starch
35 parts in dextrin
1.0 parts in tartaric acid
Ethanol 50% is an amount of
2 parts of magnesium stearate
Process for preparing medicine of the present invention is as follows:
A. the preparation of Flos Lonicerae concentrated extract mixture: Flos Lonicerae is screened, remove impurity, leaf, stalk and impurity, Flos Lonicerae adds 15 times of water gagings and decocted 1 hour, filter, medicinal residues add 10 times of water gagings again and decoct half an hour, filter, and merge 4 times that fry in shallow oil small piece of land surrounded by water liquid and be concentrated into the medical material amount, add 20% lime cream and transfer PH to 12, leaching precipitate, precipitate add 2 times of amount ethanol suspendibles, transfer PH to 3-4 with 50% sulphuric acid, fully stir, filter, it is 6.5-7.0 that filtrate is neutralized to PH with 40% sodium hydroxide solution, filters, reclaim ethanol, concentrate after drying.Selected more in addition 1/10 amount Flos Lonicerae, crushed after being dried is crossed 120 mesh sieves; Mix with gained Flos Lonicerae concentrated extract, standby.
B. the preparation of tablet:, put mixing in the electronic mixer of rustless steel with vitamin C, Flos Lonicerae concentrated extract mixture, starch, dextrin.Tartaric acid is dissolved in 95% ethanol simultaneously, once add in the Vitamin C mixture powder, mix homogeneously, make soft material, once make the wet grain of 20-40 order by 20 order nylon mesh, put and use 60-70 ℃ of drying in the drying baker, dry granular is by 14 mesh sieves, add the magnesium stearate mixing, according to a conventional method tabletting.
Claims (3)
1, a kind of treatment stomatocace medicine, it is characterized by its primary raw material is vitamin C, and content 30-90 part is an adjuvant with Flos Lonicerae concentrated extract 5-50 part, starch 10-40 part, dextrin 25-40 part, and its shape can be made into various dosage forms and uses.
2, require described treatment stomatocace medicine according to right 1, it is characterized in that directly being attached on the stomatocace face and treating with containing the various dosage form medicines of high-load vitamin C.
3, require described treatment stomatocace medicine according to right 1, it is characterized in that also can adding appropriate amount of auxiliary materials and flavoring agent in the manufacturing process.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 03113217 CN1247215C (en) | 2003-04-14 | 2003-04-14 | Medicine for treating mouth mucous ulcer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 03113217 CN1247215C (en) | 2003-04-14 | 2003-04-14 | Medicine for treating mouth mucous ulcer |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1537563A true CN1537563A (en) | 2004-10-20 |
CN1247215C CN1247215C (en) | 2006-03-29 |
Family
ID=34320009
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 03113217 Expired - Fee Related CN1247215C (en) | 2003-04-14 | 2003-04-14 | Medicine for treating mouth mucous ulcer |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1247215C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103405681A (en) * | 2012-03-31 | 2013-11-27 | 郭鸿 | Preparation method of lozenge for treating oral ulcer |
-
2003
- 2003-04-14 CN CN 03113217 patent/CN1247215C/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103405681A (en) * | 2012-03-31 | 2013-11-27 | 郭鸿 | Preparation method of lozenge for treating oral ulcer |
Also Published As
Publication number | Publication date |
---|---|
CN1247215C (en) | 2006-03-29 |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C19 | Lapse of patent right due to non-payment of the annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |