CN1240346C - Intelligentized radio frequency thermoradiotherapeutic instrument for bladder - Google Patents

Intelligentized radio frequency thermoradiotherapeutic instrument for bladder Download PDF

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Publication number
CN1240346C
CN1240346C CN 200410025397 CN200410025397A CN1240346C CN 1240346 C CN1240346 C CN 1240346C CN 200410025397 CN200410025397 CN 200410025397 CN 200410025397 A CN200410025397 A CN 200410025397A CN 1240346 C CN1240346 C CN 1240346C
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CN
China
Prior art keywords
radio
radio frequency
peristaltic pump
bladder
heat
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Expired - Fee Related
Application number
CN 200410025397
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Chinese (zh)
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CN1593359A (en
Inventor
陈亚珠
潘钢
白景峰
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Shanghai Jiaotong University
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Shanghai Jiaotong University
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Priority to CN 200410025397 priority Critical patent/CN1240346C/en
Publication of CN1593359A publication Critical patent/CN1593359A/en
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Publication of CN1240346C publication Critical patent/CN1240346C/en
Expired - Fee Related legal-status Critical Current
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Abstract

The present invention relates to an intelligentized radio frequency intracavity thermal chemotherapy therapeutic instrument for the bladder for the field of medical appliances. The instrument comprises a multichamber therapeutic guide pipe, a temperature sensor, a radio frequency heater, a radio frequency heating electrode, a sensor adapter circuit, a data inputting and outputting circuit, an instrument body and a peristaltic pump, wherein the peristaltic pump is arranged on an installing plate of an upper layer in the instrument body; the radio frequency heating electrode and the temperature sensor are arranged on the outer surface of the multichamber therapeutic guide pipe; the radio frequency heater is connected with the radio frequency heating electrode by a leading wire; the temperature sensor is connected to the sensor adapter circuit by a leading wire; the data inputting and outputting circuit is connected to the sensor adapter circuit and the radio frequency heater by a leading wire. The radio frequency heater of the present invention can be used for directly heating medicine liquid in a cavity in a controllable mode, and the temperature sensor is used for measuring the temperature of the medicine liquid in the bladder cavity of a human body. The peristaltic pump can rotate in a forward direction and in a reverse direction in a controlled mode. Heating temperature and liquid injecting flow can be controlled by a computer, and the instrument has the advantages of rapid heating speed, rapid and stable temperature control, simple system and convenient use.

Description

Intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument
Technical field
The present invention relates to a kind of thermochemotherapy device, specifically is a kind of intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument, is used for technical field of medical instruments.
Background technology
With the bladder cancer is example, can not carry out resection operation to some, or symptom is imitated the case that gently can carry out resection operation.Available chemotherapy medicinal liquid injects in the bladder cavity and is heated to 42 ℃~44 ℃ and carries out undamaged thermochemotherapy combination therapy.The clinical meaning of thermochemotherapy technology is that it can in conjunction with the synergism of thermotherapy, chemotherapy and thermochemotherapy, effectively eliminate cancer and free cancer cell in the bladder cavity according to the different heat resistances of tumor tissues and normal structure in the bladder cavity.Popularizing of thermochemotherapy technology needs a kind of automaticity height in the bladder cavity, can inject the novel medical device that quantitative chemotherapy medicinal liquid also accurately, fast, is stably regulated chemotherapy fluid temperature in the bladder cavity in the trend bladder cavity.
Through the retrieval of prior art is found: Chinese patent application numbers 93248061.6, notification number CN2183747Y, name is called: bladder cancer intracavitary hyperthermia instrument.This patent application technology has solved the problem of aspects such as medicinal liquid is heated, fluid injection to a certain extent, but has the shortcoming and defect of some: heating means are simple, can only carry out the organ surface treatment, not porous organs and tissues degree of depth treatment; Fail to provide treatment parameter and important organ to measure the variation of temperature curve, be unfavorable for real-time monitoring; Temperature control is too coarse, and the temperature control scope can not be adjustable continuously; Do not adopt pump to drive fluid injection and tapping, make fluid injection and tapping inconvenience.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, characteristics at above-mentioned deficiency and bladder cavity, a kind of intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument is provided, make it can guarantee constant treatment temperature in the human body bladder cavity, with the graphical interfaces form, can be dynamically and interactive mode the temperature control scope is set continuously, reach the effectively plyability non-invasive therapy means of accurately keeping in bladder cavity inner surface tissue and the degree of depth tissue.
The present invention is achieved by the following technical solutions, the present invention includes: multi-cavity treatment conduit, temperature sensor, radio heater, the radio frequency heating electrode, the pick off adapter circuit, the data imput output circuit, fuselage, peristaltic pump, peristaltic pump is arranged on the interior upper strata installing plate of fuselage, the outer surface of multi-cavity treatment conduit is provided with radio frequency heating electrode and temperature sensor, radio heater 9 connects the radio frequency heating electrode by lead-in wire, temperature sensor is connected to the pick off adapter circuit by lead-in wire, and the data imput output circuit is connected respectively to pick off adapter circuit and radio heater by lead-in wire.Peristaltic pump connects the data imput output circuit by lead-in wire.The peristaltic pump pump head can forward and reversely rotate.The transfusion house steward is set on the pump head of peristaltic pump.
Described data imput output circuit is A/D and D/A converter, and the data imput output circuit is installed in industrial computer inside.Described industrial computer is arranged on the table top top of fuselage.Described medicinal fluid bag is arranged on the interior upper strata installing plate of fuselage.Described radio heater is arranged on the middle installing plate of fuselage.On the bottom installing plate in the fuselage recycling bin is set also.
During use, inject the medicinal liquid of a certain amount of preparation in the medicinal fluid bag, open manual fluid injection pinch off valve, injection catheter is gone up multi-cavity treatment conduit through connecting behind the peristaltic pump.Operator select the fluid injection mode by computer, set flow (per minute 100~200ml); Feel control chamber giving drugs into nose liquid measure by B ultrasonic detection and patient, after making medicinal liquid be full of intracavity by doctor's requirement, close manual medicinal liquid pinch off valve, cancellation fluid injection mode enters therapeutic modality, promptly under the control of industrial computer, peristaltic pump stops, and treats supravasal radio frequency heating electrode by radio heater by multi-cavity the medicinal liquid of intracavity is heated.Intracavity medicine temperature rises rapidly and is stable at setting value; Will urinate in the treatment, open the pinch off valve of manually releasing, select the mode of releasing to make the peristaltic pump backward rotation by computer, the liquid that the tapping conduit comes out flows directly into recycling bin; After urinating, close the pinch off valve of manually releasing, open manual fluid injection pinch off valve, select fluid injection mode (peristaltic pump is rotated in the forward) to carry out intracavity and replenish medicinal liquid, in medicinal liquid replenishes and has one's bosom filled with after, close manual fluid injection pinch off valve, cancellation fluid injection mode is selected therapeutic modality.Sustainable treatment 60~120 minutes, in therapeutic process, signal according to the human bladder's intracavity fluid temperature (being generally 42~44 ℃) set and intracavity fluid temperature pick off is controlled radio heater by automatic adjusting of computer, the endoceliac fluid temperature of warrantor remains on predetermined value, reaches therapeutic effect.Treatment is opened the pinch off valve of manually releasing after finishing, and selects the mode of releasing to make the peristaltic pump backward rotation by computer, and the medicinal liquid of intracavity enters recycling bin under peristaltic pump drives.
Medicinal fluid bag, tube for transfusion and multi-cavity treatment pipe all adopt disposable sterilization medicinal fluid bag and medical grade silicon rubber pipe, and each treatment back is all changed, guarantee whole liquid road aseptic and not with extraneous and other device contacts, stop cross infection.
The present invention adopts at human bladder's intracavity direct heating, efficiency of heating surface height.Tissue outside the bladder (is not subjected to the hot injury as urethra; Adopt a pump to carry out fluid injection and release, simple in structure, control is convenient.Under industrial computer control, the treatment temperature can be fast, stable, adjust to therapeutic domain exactly, system simplification is installed and tube for transfusion is changed conveniently, the continuous firing performance improves; Adopt control control chamber internal therapy temperature heat time heating time, body inner liquid medicine temperature is controlled within the effective scope.The employing of industrial computer makes the medical worker both can monitor, predict and assess therapeutic effect immediately, can adjust in real time the gentle dose of the medicine in the bladder cavity as required again.
Description of drawings
Fig. 1 is architecture figure of the present invention
Fig. 2 is the principle of the invention and annexation sketch map
In the drawings, medicinal fluid bag 1, manually fluid injection pinch off valve 2, injection catheter 3 (representing with heavy line among Fig. 1), trident isocon 4, transfusion house steward 5 (representing with heavy line among Fig. 1), peristaltic pump 6, multi-cavity treatment conduit 7, temperature sensor 8, radio heater 9, radio frequency heating electrode 10, manually tapping pinch off valve 11, recycling bin 12, tapping conduit 13 (representing with heavy line among Fig. 1), pick off adapter circuit 14, industrial computer 15, data imput output circuit 16, fuselage 17.
The specific embodiment
As Fig. 1, shown in 2, the present invention includes: multi-cavity treatment conduit 7, temperature sensor 8, radio heater 9, radio frequency heating electrode 11, pick off adapter circuit 14, data imput output circuit 16, fuselage 17, it is characterized in that, also comprise: peristaltic pump 6, peristaltic pump 6 is arranged on the upper strata installing plate in the fuselage 17, the outer surface of multi-cavity treatment conduit 7 is provided with radio frequency heating electrode 11 and temperature sensor 8, radio heater 9 connects radio frequency heating electrode 11 by lead-in wire, temperature sensor 8 is connected to pick off adapter circuit 14 by lead-in wire, and data imput output circuit 16 is connected to pick off adapter circuit 14 and radio heater 9 by lead-in wire.Peristaltic pump 6 connects data imput output circuit 16 by lead-in wire.Peristaltic pump 6 pump heads can forward and reversely rotate.Transfusion house steward 5 is set on the pump head of peristaltic pump 6.
Described data imput output circuit 16 is A/D and D/A converter, and data imput output circuit 16 is installed in industrial computer 15 inside.
Described industrial computer 15 is arranged on the table top top of fuselage 17.
Described medicinal fluid bag 1 is arranged on the upper strata installing plate in the fuselage 17.
Described radio heater 9 is arranged on the middle installing plate of fuselage 17.
On the bottom installing plate in the fuselage 17 recycling bin 12 is set also.
During use, multi-cavity treatment conduit 7 inserts human bladder's intracavity, injection catheter 3 one ends are connected on the liquid outlet of medicinal fluid bag 1, injection catheter 3 other ends warp is an end of fluid injection pinch off valve 2, connection trident isocon 4 manually, and transfusion house steward 5 one ends connect trident isocon 4, other end process peristaltic pump 6 backs are treated conduit 7 with multi-cavity and are connected.Promoted to flow through transfusion house steward 6 by peristaltic pump from the medicinal liquid of medicinal fluid bag 1 through injection catheter 3, enter multi-cavity treatment pipe 7, last medicinal liquid injects human bladder's intracavity through multi-cavity treatment pipe 7, is marked with abundant medicinal liquid at human bladder's intracavity.Fluid temperature pick off 8 is measured the intracavity fluid temperature, the fluid temperature of monitoring intracavity.
Temperature sensor 8 output signals are amplified through pick off adapter circuit 14, convert digital signal input industrial computer 15 to by data imput output circuit 15.Industrial computer 15 is finished the driving to executive components such as radio heater and peristaltic pumps by radio heater 9 and peristaltic pump 6 that data imput output circuit 16 output signals connect respectively.
During treatment, after being marked with abundant medicinal liquid, human bladder's intracavity closes manual fluid injection pinch off valve 2, radio heater 9 heats by the electrode pair intracavity medicinal liquid on the multi-cavity treatment pipe 7, fluid temperature pick off 8 is measured the intracavity fluid temperature, and under industrial computer 15 controls the fluid temperature of intracavity is adjusted to therapeutic domain rapidly.Industrial computer 15 can be regulated the intracavity fluid temperature automatically.The doctor can adjust treatment temperature and cavity liquid injecting amount of liquid medicine in real time according to patient status and reaction.
In the therapeutic process, will urinate in treatment as patient, as open the pinch off valve 11 of manually releasing, select the mode of releasing to make peristaltic pump 6 backward rotation by industrial computer 15, the liquid that tapping conduit 13 comes out flows directly into recycling bin 12; After urinating, close the pinch off valve 11 of manually releasing, open manual fluid injection pinch off valve 2, select fluid injection mode (peristaltic pump 6 is rotated in the forward) to carry out intracavity and replenish medicinal liquid, in medicinal liquid replenishes and has one's bosom filled with after, close manual fluid injection pinch off valve 2, cancellation fluid injection mode is selected therapeutic modality.
After treatment finishes, select the modes of releasing to make peristaltic pump 6 oppositely start, open manual tapping pinch off valve 10, the remaining medicinal liquid of human bladder's intracavity is entered recycling bin 12 by industrial computer 14.
Medicinal fluid bag 1 among the present invention, injection catheter 3, tapping conduit 13, transfusion house steward 6, temperature sensor 8, multi-cavity treatment pipe 7 all are disposable uses, and medicinal liquid only directly contacts with medicinal fluid bag 1, injection catheter 3, tapping conduit 13, fluid temperature pick off 8, multi-cavity treatment pipe 7 during treatment.

Claims (9)

1, a kind of intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument, comprise: multi-cavity treatment conduit (7), temperature sensor (8), radio heater (9), radio frequency heating electrode (11), pick off adapter circuit (14), data imput output circuit (16), fuselage (17), it is characterized in that, also comprise: peristaltic pump (6), peristaltic pump (6) is arranged on the interior upper strata installing plate of fuselage (17), the outer surface of multi-cavity treatment conduit (7) is provided with radio frequency heating electrode (11) and temperature sensor (8), radio heater (9) connects radio frequency heating electrode (11) by lead-in wire, temperature sensor (8) is connected to pick off adapter circuit (14) by lead-in wire, data imput output circuit (16) is connected respectively to pick off adapter circuit (14) and radio heater (9) by lead-in wire, peristaltic pump (6) connects data imput output circuits (16) by lead-in wire, and industrial computer (15) is by being installed in its inner data imput output circuit (16) control radio heater (9) and peristaltic pump (6).
2, intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument as claimed in claim 1 is characterized in that, described peristaltic pump (6) connects data imput output circuits (16) by lead-in wire.
3, as the intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument of claim 1 or 2, it is characterized in that described peristaltic pump (6) pump head can forward and reversely rotate.
4, as the intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument of claim 1 or 2, it is characterized in that, transfusion house steward (5) is set on the pump head of described peristaltic pump (6).
5, intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument as claimed in claim 1 is characterized in that described data imput output circuit (16) is A/D and D/A converter, and data imput output circuit (16) is installed in industrial computer (15) inside.
6, intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument as claimed in claim 1 is characterized in that, described industrial computer (15) is arranged on the table top top of fuselage (17).
7, intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument as claimed in claim 1 is characterized in that, described medicinal fluid bag (1) is arranged on the interior upper strata installing plate of fuselage (17).
8, intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument as claimed in claim 1 is characterized in that described radio heater (9) is arranged on the middle installing plate of fuselage (17).
9, intelligent bladder radio-frequency cavity interior-heat chemotherapeutic treatment instrument as claimed in claim 1 is characterized in that, on the bottom installing plate in the described fuselage (17) recycling bin (12) is set also.
CN 200410025397 2004-06-24 2004-06-24 Intelligentized radio frequency thermoradiotherapeutic instrument for bladder Expired - Fee Related CN1240346C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200410025397 CN1240346C (en) 2004-06-24 2004-06-24 Intelligentized radio frequency thermoradiotherapeutic instrument for bladder

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200410025397 CN1240346C (en) 2004-06-24 2004-06-24 Intelligentized radio frequency thermoradiotherapeutic instrument for bladder

Publications (2)

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CN1593359A CN1593359A (en) 2005-03-16
CN1240346C true CN1240346C (en) 2006-02-08

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2914326B1 (en) 2012-11-02 2023-08-16 Neurotronic, Inc. Chemical ablation formulations
US10537375B2 (en) 2015-04-24 2020-01-21 Neurotronic, Inc. Chemical ablation and method of treatment for various diseases
CN103751880B (en) * 2014-01-08 2015-12-09 上海交通大学 Circulation pipeline device for intraperitoneal chemohyperthermia
GB201412842D0 (en) * 2014-07-18 2014-09-03 Combat Medical Sl Catheter for the delivery of therapeutic fluid
CN113040895A (en) 2014-10-30 2021-06-29 纽敦力公司 Chemical ablation and methods for treating various diseases
CN114452464A (en) * 2021-12-14 2022-05-10 中国船舶重工集团公司第七一六研究所 Automatic peritoneal dialysis monitoring control system and control method thereof

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Granted publication date: 20060208

Termination date: 20130624