CN1326580C - Infrared heat perfusion therapeutic apparatus - Google Patents
Infrared heat perfusion therapeutic apparatus Download PDFInfo
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- CN1326580C CN1326580C CNB200410017707XA CN200410017707A CN1326580C CN 1326580 C CN1326580 C CN 1326580C CN B200410017707X A CNB200410017707X A CN B200410017707XA CN 200410017707 A CN200410017707 A CN 200410017707A CN 1326580 C CN1326580 C CN 1326580C
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Abstract
The present invention relates to an infrared heat perfusion therapeutic apparatus. A perfusion conduit is wound on an infrared heater supporting frame, and an infrared electric heating pipe is used for heating perfused medicinal liquid in a non-contact type. A temperature measuring probe is used for measuring the temperature of ingress and egress medicinal liquid of a human body, and a suspended type weighting sensor is used for detecting the weight of a medicine bag so as to indirectly measure the perfused medicinal quantity of the human body. Measuring values are respectively used as the feedback of treatment temperature and flow regulation, and heating time and cycle flow quantities are controlled by an industrial control computer respectively through an electromagnetic valve driving circuit, a heater driving circuit and a peristaltic pump driving circuit to guarantee constant treatment temperature and the balance of ingress and egress medicinal liquid in the human body. The present invention has the advantages of small thermal capacity, rapid temperature control, stability, compact system, friendly interface, convenient use, etc.
Description
Technical field
The present invention relates to a kind of infra-red heat perfusion therapeutic instrument, is a kind of warm liquid device for casting based on infrared heating technique, is used for preventing and treating after the malignant tumor excision in the splanchnocoel heat, the chemotherapy combination therapy of relapse and metastasis.Belong to technical field of medical instruments,
Background technology
Soaking into male gastrointestinal cancer with serous coat is example, even it is implemented healing property radical resection, the most patients of postoperative also can be dead because of the peritoneum relapse and metastasis.Its main cause is that intraperitoneal exists free cancer cell and remaining little cancer, the active cancerous cell " seed " that these come off may be planted in subcutaneous connective tissue provided between operation wound and peritoneal surface are exposed " soil " fully, thereby causes local recurrence or transfer.Warm-heat perfusion (intraperitoneal hyperthermic perfusion in the splanchnocoel, IPHP) clinical meaning of chemotherapy technology is that it can be according to the different heat resistances of tumor tissues and normal structure, in conjunction with the synergism of thermotherapy, chemotherapy and thermochemotherapy, effectively eliminate remaining cancer of intraperitoneal and free cancer cell.Popularizing of IPHP chemotherapy technology needs a kind of automaticity height, the novel medical device that can accurately, fast, stably regulate filling temperature and flow.China national Department of Intellectual Property successively discloses several IPHP chemotherapy equipment patents: the perfusion anticancer machine (notification number 2211286) of heating, warm-heat perfusion chemical curing instrument (notification number 2234280), hyperthermic perfusion chemotherapy machine (notification number 2339233), abdominal cavity constant temperature warm-heat perfusion instrument (notification number 2511268), microwave thermal perfusion circulation treatment machine (notification number 2538343), a kind of hot perfusion chemotherapeutic apparatus (notification number 2538365).The problem of aspects such as driving, backflow filtration and/or lancet design is heated, poured into to above instrument from having solved medicinal liquid in varying degrees, but have some common shortcoming and defect:
1. modes such as water bath exchange, the whole heating of medicated bag cause system's thermal capacity increase, temperature control rapidity difference and be prone to overshoot.
2. temperature control accuracy and stability are not good, can not realize that especially temperature regulates in real time.
3. the Flow-rate adjustment inaccuracy is difficult to guarantee constant perfusion dose in the splanchnocoel.
4. fail to provide treatment parameter and important organ to measure the variation of temperature curve, be unfavorable for real-time monitoring.
5. system is huge, and complicated operation is installed, changed to conduit, uses inconvenience.
Summary of the invention
The objective of the invention is at above-mentioned deficiency, design a kind of infra-red heat perfusion therapeutic instrument, can finish automatically that medicinal liquid is heated, the real-time monitoring of Flow-rate adjustment, turnover human body fluid temperature and flow, with dynamic and interactive mode, accurately keep treatment environment suitable in the splanchnocoel.
For reaching this purpose, in the technical scheme of the present invention, on the infrared heater support, twine perfusion cannula, adopt infrared electric heating tube that perfusion solution is carried out contactless heating, make the treatment temperature can adjust to optimum range fast and stable; Adopt thermoprobe to measure turnover human body fluid temperature, adopt the suspension type LOAD CELLS to detect medicated bag weight to pour into dose in the indirect measurement human body, and respectively with the feedback of measured value as treatment temperature and Flow-rate adjustment, by computer control heat time heating time and circular flow, guarantee constant treatment temperature and turnover medicinal liquid balance in the human body.
Concrete structure of the present invention is: medicinal fluid bag hangs under the LOAD CELLS, and the holding wire of LOAD CELLS is connected to sensor adapter, is sent to computer through variable connector and data imput output circuit, reflects the perfusion liquid measure indirectly with medicinal fluid bag Chinese medicine liquid measure.The liquid outlet of medicinal fluid bag connects perfusion cannula, perfusion cannula is through manually pinch off valve, perfusion peristaltic pump, infrared heater link to each other with priming connectors, the outlet of priming connectors connects the importing drainage tube (or puncture needle) on the human body, be inserted with the perfusion solution thermoprobe on the priming connectors, to measure the perfusion solution temperature.The heating-up temperature pick off is in infrared heater, with the HEATER FOR MEASURING temperature.Burner on light is in parallel on circuit with infrared heater.One end of backflow connector connects the derivation drainage tube (or puncture needle) on the human body, and the other end links to each other with return-flow catheter, is inserted with backflow medicinal liquid thermoprobe on the backflow connector, to measure the backflow fluid temperature.Return-flow catheter is bifurcated behind the backflow peristaltic pump, and one the tunnel is connected with the inlet of medicinal fluid bag through circulation electromagnetism pinch off valve; Another road links to each other with recycling bin through the electromagnetism pinch off valve of releasing, and collects the treatment waste liquid by recycling bin.Heating-up temperature pick off, perfusion solution thermoprobe, backflow medicinal liquid thermoprobe and the signal that is distributed in the sets of temperature sensors on the human body are delivered to industrial computer through sensor adapter, variable connector, data imput output circuit.Industrial computer sends to electromagnetic valve the control signal of heater and peristaltic pump by driving circuit for electromagnetic valve, heater drive circuit and peristaltic pump (motor) drive circuit.
When the present invention worked, LOAD CELLS was suspended on the medicinal fluid bag, perfusion cannula through the perfusion peristaltic pump after with helical form flat around infrared heater on pipe holder.Operator select reperfusion mode (circulating or open) by computer, set the gentle flow (per minute 100～200ml) of perfusion medicine; Start infrared heater and perfusion peristaltic pump, gas in the emptying transfusion catheter under the control of industrial computer, carries out the heating of noncontact infrared radiation by infrared heater to mobile medicinal liquid in the tube for transfusion.Perfusion cannula outlet medicine temperature rises rapidly and is stable at setting value; Connect perfusion cannula and the pre-buried importing drainage tube of human body (or puncture needle), the supravasal circulation electromagnetism of the closing volume pinch off valve and the electromagnetism pinch off valve of releasing, after making medicinal liquid be full of the abdominal cavity by doctor's requirement, start the backflow peristaltic pump, open the electromagnetism pinch off valve of releasing on the return-flow catheter, the liquid that return-flow catheter comes out flows directly into recycling bin (open) or opens circulation electromagnetism pinch off valve on the return-flow catheter, and the liquid that comes out of refluxing enters medicinal fluid bag and utilizes (circulating) again.Continue perfusion 60～120 minutes, in therapeutic process, can regulate automatically by computer and control the switch of infrared heater and the rotating speed of two peristaltic pumps according to input, output human body fluid temperature (input, output human body medicine temperature generally are respectively: 44～48.7 ℃ and 40～42 ℃), the intravital fluid temperature of warrantor remains on predetermined value, reaches therapeutic effect.Also semi-automatically manual setting perfusion solution temperature and flow; Treatment is closed the perfusion peristaltic pump after finishing, and the remaining medicinal liquid of intraperitoneal enters recycling bin under the driving of backflow peristaltic pump.
Medicinal fluid bag of the present invention and tube for transfusion all adopt disposable sterilization medicinal fluid bag and medical grade silicon rubber pipe, and each treatment back is all changed, guarantee whole liquid road aseptic and not with extraneous and other device contacts, stop cross infection.
The present invention adopts two peristaltic pumps to control the flow of turnover medicinal liquid respectively, realizes the constant of liquid measure in the body to regulate the turnover flow respectively, has overcome the drawback of a pump work.Suspension type medicinal fluid bag weight method can be measured indirectly and pour into dose in the human body.As feedback quantity, can be used for regulating turnover human body medicinal liquid balance, keep constant perfusion dose in the human body.Under open reperfusion mode, also can accurately measure actual irrigation flow.
The present invention adopts infrared heater that perfusion solution is carried out contactless heating, and perfusion cannula is flat on the heating frame of infrared heater with helical form, because the efficiency of heating surface height of infrared heater, system's thermal capacity is little, so the temperature control rapidity is good.Under industrial computer control, even be lower than under the condition of 20 ℃ of setting values in initial medicine temperature, the treatment temperature also can be fast, stablize, adjust to exactly optimum range.Use instrument to need not preheating and insulation measure under clinical setting, system simplification is installed and tube for transfusion is changed conveniently, and the continuous firing performance improves.
The present invention adopts control heat time heating time and two kinds of methods of control circular flow to come control volume internal therapy temperature, and body inner liquid medicine temperature is controlled within the effective scope.The employing of industrial computer makes the medical worker both can monitor, predict and assess therapeutic effect immediately, can adjust in real time the gentle flow of perfusion medicine as required again.
Description of drawings
Fig. 1 is system principle of the present invention and annexation sketch map.
In Fig. 1,1 medicinal fluid bag, 2 LOAD CELLSs, 3 manual pinch off valves, 4 perfusion cannulas (representing with heavy line among the figure), 5 perfusion peristaltic pumps, 6 infrared heaters, 7 heating-up temperature pick offs, 8 burner on lights, 9 priming connectors, 10 perfusion solution thermoprobes, 11 sets of temperature sensors, 12 backflow connectors, 13 backflow medicinal liquid thermoprobes, 14 backflow peristaltic pumps, 15 circulation electromagnetism pinch off valves, the 16 electromagnetism pinch off valves of releasing, 17 recycling bins, 18 return-flow catheters (representing with heavy line among the figure), 19 sensor adapters, 20 variable connectors, 21 data imput output circuits, 22 industrial computers, 23 display, 24 driving circuit for electromagnetic valve, 25 heater drive circuits, 26 peristaltic pumps (motor) drive circuit.
Fig. 2 is main structure figure of the present invention.
In Fig. 2,1 medicinal fluid bag, 2 LOAD CELLSs, 3 manual pinch off valves, 4, perfusion cannula, 5 perfusion peristaltic pumps, 6 infrared heaters, 9 priming connectors, 10 perfusion solution thermoprobes, 12 backflow connectors, 13 backflow medicinal liquid thermoprobes, 14 backflow peristaltic pumps, 15 circulation electromagnetism pinch off valves, the 16 electromagnetism pinch off valves of releasing, 17 recycling bins, 18 return-flow catheters, 22 industrial computers, 23 display, 27 outstanding bag framves, 28 around pipe holder, 29 fuselages.
The specific embodiment
Below in conjunction with accompanying drawing technical scheme of the present invention is further described.
System principle of the present invention and annexation as shown in Figure 1, medicinal fluid bag 1 hangs over LOAD CELLS 2 times, LOAD CELLS 2 holding wires are connected to sensor adapter 19.The liquid outlet of medicinal fluid bag 1 connects perfusion cannula 4, and perfusion cannula 4 is through manually pinch off valve 3, perfusion peristaltic pump 5, infrared heater 6 are connected to priming connectors 9, the importing drainage tube (or puncture needle) on the outlet connection human body of priming connectors 9.Be inserted with perfusion solution thermoprobe 10 on the priming connectors 9.Burner on light 8 is in parallel on circuit with infrared heater 6.Heating-up temperature pick off 7 is installed in the infrared heater 6.Be inserted with backflow medicinal liquid thermoprobe 13 on the backflow connector 12.One end of backflow connector 12 connects the derivation drainage tube (or puncture needle) on the human body, the other end links to each other with return-flow catheter 18, return-flow catheter 18 is bifurcated behind backflow peristaltic pump 14, one the tunnel is connected with the inlet of medicinal fluid bag 1 through circulation electromagnetism pinch off valve 15, and another road links to each other with recycling bin 17 through the electromagnetism pinch off valve 16 of releasing.Signal T4～the T15 of heating-up temperature pick off 7 signal T3, perfusion solution thermoprobe 10 signal T1, backflow medicinal liquid thermoprobe 13 signal T2 and sets of temperature sensors 11 delivers to industrial computer 22 through sensor adapter 19, variable connector 20, data imput output circuit 21.Industrial computer 22 through data imput output circuit 21 and driving circuit for electromagnetic valve 24, heater drive circuit 25 and peristaltic pump drive circuit 26 send control signal K2 to circulation electromagnetism pinch off valve 15, to the control signal K3 of the electromagnetism pinch off valve 16 of releasing, to the control signal H1 of infrared heater 6 with to control signal M1, the M2 of perfusion peristaltic pump 5, backflow peristaltic pump 14.
Structure of the present invention as seen from Figure 2 constitutes, and the superiors in fuselage 29 are equipped with perfusion peristaltic pump 5 and backflow peristaltic pump 14.The second layer at fuselage 29 is equipped with infrared heater 6.In the bottom of fuselage 29 industrial computer 22 is housed.Display 23 is installed on the table top of fuselage 29.Outstanding bag frame 27 is placed in the next door of fuselage 29, hangs with LOAD CELLS 2 on the outstanding bag frame 27, and medicinal fluid bag 1 hangs over LOAD CELLS 2 belows, and its liquid outlet links to each other with perfusion cannula 4.Perfusion cannula 4 is through manual pinch off valve 3 and after being coiled on the pump head that pours into peristaltic pump 5, again helical form flat in infrared heater 6 on pipe holder 28, behind infrared heater 6, the other end of perfusion cannula 4 connects the priming connectors 9 that is inserted with perfusion solution thermoprobe 10.Return-flow catheter 18 1 ends connect the priming connectors 12 be inserted with backflow medicinal liquid thermoprobe 13, on the pump head of the other end through being coiled in backflow peristaltic pump 14 after bifurcated, the one tunnel is connected with the inlet of medicinal fluid bag 1 through circulation electromagnetism pinch off valve 15; Another road links to each other with recycling bin 17 through the electromagnetism pinch off valve 16 of releasing.
Work process of the present invention is as follows; LOAD CELLS 2 is suspended on the bag frame 27, and medicinal fluid bag 1 hangs over LOAD CELLS 2 times.The built-in drainage screen of medicinal fluid bag is used for the free cancer cell of filtering backflow.Perfusion cannula 4 is successively through manual pinch off valve 3, perfusion peristaltic pump 5 and infrared heater 6, and 6 pairs of infrared heaters carry out the heating of noncontact infrared radiation by the medicinal liquid that perfusion peristaltic pump 5 promotes to flow through perfusion cannula 4.Burner on light 8 is in parallel on circuit with infrared heater 6, the on off state of infrared heater 6 in the indication regulation process.Temperature sensor 7 is housed, the HEATER FOR MEASURING heating-up temperature in the infrared heater 6.The two ends that are inserted with the priming connectors 9 of perfusion solution thermoprobe 10 link to each other with importing drainage tube (or puncture needle) in the pre-buried human body with perfusion cannula 4 respectively.Perfusion solution thermoprobe 10 is measured the perfusion solution temperature.Sets of temperature sensors 11 sticks on surfaces such as human body important organ such as spleen, liver, lung, brain, monitors the temperature of these internal organs.The derivation drainage tube (or puncture needle) that is embedded in the human body is connected with return-flow catheter 18 by backflow connector 12, is inserted with backflow medicinal liquid thermoprobe 13 in the backflow connector 12.Backflow medicinal liquid thermoprobe 13 is measured the temperature of backflow medicinal liquid.Return-flow catheter 18 is divided into two-way behind backflow peristaltic pump 14: the one tunnel through the electromagnetism pinch off valve 16 connection recycling bins 17 of releasing, and are called and reclaim the loop; Medicated bag is flowed back to through circulation electromagnetism pinch off valve 15 in another road, is called reflux circuit.
Temperature and LOAD CELLS output signal are amplified through pick off adapter circuit 19, and variable connector 20 gatings convert digital signal input industrial computer 22 to by data imput output circuit 21.Industrial computer 22 is finished the driving to executive components such as pinch off valve, peristaltic pump and heaters by driving circuit for electromagnetic valve 24, heater drive circuit 25 and peristaltic pump drive circuit 26 output signals that data imput output circuit 21 connects respectively.
During treatment, disconnect priming connectors 9 and import being connected of drainage tube, open manual pinch off valve 3, start perfusion peristaltic pump 5 and infrared heater 6, air in the emptying perfusion cannula 4, and under industrial computer 22 is controlled, will export the medicine temperature and be adjusted to optimum range rapidly.Then, with priming connectors 9 with import drainage tube and link to each other, medicinal liquid inflow human body is full of the abdominal cavity by doctor's requirement.Then open backflow peristaltic pump 14.Backflow peristaltic pump 14 is backward rotation periodically, prevents that the drainage tube at backflow connector 12 places from blocking.According to different therapeutic modalities, open circulation electromagnetism pinch off valve 15 respectively, close the electromagnetism pinch off valve 16 (circulating treatment) of releasing, perhaps open the electromagnetism pinch off valve 16 of releasing, close circulation electromagnetism pinch off valve 15 (open treatment).During open treatment, the backflow medicinal liquid flows directly into recycling bin 17; During circulation treatment, the backflow medicinal liquid flows into medicinal fluid bag and utilizes again.To two kinds of therapeutic modalities, industrial computer 22 can both be regulated abdominal cavity herb liquid temperature automatically, and control perfusion dose.To circulation treatment, the medicinal fluid bag drainage screen will play free tumor tissues, the effect of purification medicinal liquid isolated.In the therapeutic process, the doctor can adjust treatment temperature and irrigation flow in real time according to patient status and reaction.After treatment finishes, close perfusion peristaltic pump 5, open the electromagnetism pinch off valve 16 of releasing, close circulation electromagnetism pinch off valve 15, remaining medicinal liquid in the human body is entered recycling bin 17.
Claims (3)
1, a kind of infra-red heat perfusion therapeutic instrument, it is characterized in that by medicinal fluid bag (1), LOAD CELLS (2), manual pinch off valve (3), perfusion cannula (4), perfusion peristaltic pump (5), infrared heater (6), heating-up temperature pick off (7), burner on light (8), priming connectors (9), perfusion solution thermoprobe (10), sets of temperature sensors (11), backflow connector (12), backflow medicinal liquid thermoprobe (13), backflow peristaltic pump (14), circulation electromagnetism pinch off valve (15), the electromagnetism pinch off valve (16) of releasing, recycling bin (17), return-flow catheter (18) sensor adapter (19), variable connector (20), data imput output circuit (21), industrial computer (22), display (23), driving circuit for electromagnetic valve (24), heater drive circuit (25), peristaltic pump drive circuit (26), outstanding bag frame (27), around pipe holder (28), fuselage (29) is formed, medicinal fluid bag (1) hangs under the LOAD CELLS (2), LOAD CELLS (2) holding wire is connected to sensor adapter (19), the liquid outlet of medicinal fluid bag (1) connects perfusion cannula (4), perfusion cannula (4) is through manual pinch off valve (3), perfusion peristaltic pump (5), infrared heater (6) is connected to the priming connectors (9) that is inserted with perfusion solution thermoprobe (10), the outlet of priming connectors (9) connects the importing drainage tube on the human body, burner on light (8) is in parallel on circuit with the infrared heater that heating-up temperature pick off (7) are housed (6), backflow connector (12) two ends that are inserted with backflow medicinal liquid thermoprobe (13) connect derivation drainage tube and the return-flow catheter (18) on the human body respectively, return-flow catheter (18) is bifurcated behind backflow peristaltic pump (14), one the tunnel is connected through the inlet of circulation electromagnetism pinch off valve (15) with medicinal fluid bag (1), another road links to each other with recycling bin (17) through the electromagnetism pinch off valve (16) of releasing, heating-up temperature pick off (7), perfusion solution thermoprobe (10), backflow medicinal liquid thermoprobe (13) and the signal that is distributed in the sets of temperature sensors (11) on the human body are through sensor adapter (19), variable connector (20), data imput output circuit (21) is delivered to industrial computer (22), industrial computer (22) connects driving circuit for electromagnetic valve (24) respectively through data imput output circuit (21), heater drive circuit (25) and peristaltic pump drive circuit (26), send circulation electromagnetism pinch off valve (15), the electromagnetism pinch off valve (16) of releasing, infrared heater (6) and perfusion peristaltic pump (5), the control signal of backflow peristaltic pump (14).
2, infra-red heat perfusion therapeutic instrument as claimed in claim 1, it is characterized in that described perfusion cannula (4) helical form when infrared heater (6) is flat on the heated holder (28) of infrared heater (6), the mobile medicinal liquid in the perfusion cannula (4) is carried out the heating of noncontact infrared radiation by infrared heater (6).
3, infra-red heat perfusion therapeutic instrument as claimed in claim 1 is characterized in that periodically backward rotation of described backflow peristaltic pump (14), prevents that the drainage tube that backflow connector (12) is located from blocking.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200410017707XA CN1326580C (en) | 2004-04-15 | 2004-04-15 | Infrared heat perfusion therapeutic apparatus |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB200410017707XA CN1326580C (en) | 2004-04-15 | 2004-04-15 | Infrared heat perfusion therapeutic apparatus |
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| Publication Number | Publication Date |
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| CN1562400A CN1562400A (en) | 2005-01-12 |
| CN1326580C true CN1326580C (en) | 2007-07-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB200410017707XA Expired - Fee Related CN1326580C (en) | 2004-04-15 | 2004-04-15 | Infrared heat perfusion therapeutic apparatus |
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| CN (1) | CN1326580C (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100464799C (en) * | 2005-07-14 | 2009-03-04 | 上海涌泉医疗科技发展有限公司 | Deslagging mechanism for tumor thermal perfusion therapeusis |
| CN201798846U (en) * | 2010-09-26 | 2011-04-20 | 西安好博士医疗科技有限公司 | Coelom circulation thermal-chemotherapy perfusion system |
| CN102670348A (en) * | 2012-05-28 | 2012-09-19 | 中山市中健医疗设备有限公司 | Perfusion tumor thermal therapy instrument and method for realizing safety protection |
| DE102013010106A1 (en) * | 2013-06-18 | 2014-12-18 | Fresenius Medical Care Deutschland Gmbh | Medical heat exchanger for heating medical fluids by means of an illuminator for light and medical fluid treatment device with an emitter for light |
| CN103886796B (en) * | 2014-03-13 | 2016-02-24 | 西安交通大学 | A kind of for the organ perfusion's system in surgical simulation training aids |
| CN105311696B (en) * | 2015-11-04 | 2018-08-17 | 江苏世健医疗器械有限公司 | Novel enemator |
| CN108836618B (en) * | 2018-04-28 | 2019-08-02 | 广州保瑞医疗技术有限公司 | The hot device for casting of cavity circulation |
| CN110393627A (en) * | 2019-08-29 | 2019-11-01 | 吉林省迈达医疗器械股份有限公司 | A kind of perfusion unit in use for thermochemical therapeutics for abdominal cavity |
| CN110811524A (en) * | 2019-11-08 | 2020-02-21 | 武汉佑康科技有限公司 | Visual thermotherapy device |
| CN111184923A (en) * | 2020-02-17 | 2020-05-22 | 佳木斯大学 | Medical oncology medicine intervenes treatment device |
| CN112155841B (en) * | 2020-09-04 | 2022-03-22 | 深圳市医思美科技有限公司 | Control system and control method of thermal perfusion treatment equipment |
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- 2004-04-15 CN CNB200410017707XA patent/CN1326580C/en not_active Expired - Fee Related
Patent Citations (5)
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|---|---|---|---|---|
| CN2158274Y (en) * | 1993-07-16 | 1994-03-09 | 孙光熊 | Instrument for controlling infusion |
| WO2001056638A1 (en) * | 2000-02-02 | 2001-08-09 | A. Atlantis S.A. | Heating system for warming a physiologic fluid to be infused into a patient |
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| CN2538343Y (en) * | 2002-02-27 | 2003-03-05 | 柳长庆 | Microware heat perfusion circulation therapeutic apparatus |
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| CN1562400A (en) | 2005-01-12 |
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