CN103751880B - Circulation pipeline device for intraperitoneal chemohyperthermia - Google Patents
Circulation pipeline device for intraperitoneal chemohyperthermia Download PDFInfo
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- CN103751880B CN103751880B CN201410008370.XA CN201410008370A CN103751880B CN 103751880 B CN103751880 B CN 103751880B CN 201410008370 A CN201410008370 A CN 201410008370A CN 103751880 B CN103751880 B CN 103751880B
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Abstract
The invention provides a kind of perfusion circulating pipeline device, for abdominal cavity thermotherapy, by the break-make of buckle, adjustment circulating pipeline device is adapted to different treatment stages, meets the requirement of abdominal cavity thermotherapy; Use heater plate, system is simple and reliable, to medicinal liquid without destruction; Adopt temperature-measuring tee joint, be convenient to arrange temperature detecting point, accurate detected temperatures and control temperature can be ensured, thus ensure the therapeutic effect of abdominal cavity thermotherapy; Adopt liquid-collection bag, be convenient to medicinal liquid and inject, easy to operate and can not air be mixed in cyclic process herb liquid, ensure therapeutic effect; Medicinal liquid liquid-collection bag is all recycled to after completed treatment, without revealing, environmentally safe; Pump line is configured in heating bag both sides, avoids heating bag flatulence; Arrange filter, effectively can filter out the micro-bolt of tissue, prevent the phenomenon occurring blocking pipeline in cyclic process, circulation is reliable.
Description
Technical field
The invention belongs to medical assistance instrument field, specifically a kind of medicinal liquid filling circulating pipeline device for abdominal cavity thermotherapy.
Background technology
Abdominal cavity thermotherapy utilizes the synergism of regional heavy dose of thermotherapy and chemotherapy, kill cancerous cell by heat-therapeutic action and directly kill cancerous cell by Chemotherapy, mechanically the cancerous cell come off in intraperitoneal is free is rinsed out simultaneously, its effectiveness obtains a large amount of clinical trial and confirms, it is more and the more first-selected therapeutic scheme for the treatment of belly cavity tumor by approval, but, the existing perfusion circulating pipeline device based on abdominal cavity hyperthermia-chemotherapy therapy existing defects and inconvenience in the following areas at present:
1, hyperthermia-chemotherapy before this adopts water-bath mode usually, and pipeline is simple, is difficult to realize accurate temperature controlling, cannot reaches the effect of hyperthermia-chemotherapy;
2, circulation line poor reliability, the flow processs such as medicinal liquid filling are complicated, inconvenient operation; And be easily mixed into air in cyclic process herb liquid, be difficult to remove, affect chemotherapy effect;
3, temperature detecting point complicated layout in cyclic process, is difficult to detect, and temperature control precision is difficult to ensure;
4, heat exchange tank is adopted, the equipment such as heat-exchange tube, the recovery of medicinal liquid and waste treatment inconvenience.
Summary of the invention
For existing perfusion circulating pipeline device Problems existing, the invention provides a kind of perfusion circulating pipeline device, for abdominal cavity thermotherapy.
Perfusion circulating pipeline device provided by the invention, for abdominal cavity thermotherapy, comprise circulation pipe, the pump line be arranged on peristaltic pump, liquid-collection bag, the heating bag be arranged on hot plate, threeway, temperature-measuring tee joint, filter and buckle, circulation pipe is connected with pump line, liquid-collection bag, heating bag, threeway, temperature-measuring tee joint, filter by female Luer; Pump line is used for for medicinal liquid circulation provides power, and heating bag is used for for medicine liquid heating, and temperature-measuring tee joint is for detecting the temperature of medicinal liquid, and filter is used for filtering liquid medicine, and buckle is adapted to multiple treatment stage for adjusting circulating pipeline device.
Perfusion circulating pipeline device provided by the invention, by the break-make of buckle, adjustment circulating pipeline device is adapted to different treatment stages, meets the requirement of abdominal cavity thermotherapy; Adopt circulation line and liquid-collection bag, be convenient to recovery and the waste treatment of medicinal liquid; Adopt temperature-measuring tee joint, be convenient to arrange temperature detecting point, accurate detected temperatures and control temperature can be ensured, thus ensure the therapeutic effect of abdominal cavity thermotherapy; Adopt liquid-collection bag, be convenient to medicinal liquid and inject, easy to operate and can not air be mixed in cyclic process herb liquid, ensure therapeutic effect.
Further, temperature-measuring tee joint comprises first, second and the 3rd temperature-measuring tee joint, first temperature-measuring tee joint is for detecting the temperature of the medicinal liquid flowing into abdominal cavity, and the second temperature-measuring tee joint is for detecting the temperature of the medicinal liquid flowing out abdominal cavity, and the 3rd temperature-measuring tee joint is for detecting the temperature of the medicinal liquid flowing through heating bag.
Perfusion circulating pipeline device provided by the invention, detects inflow respectively, flows out the temperature of medicinal liquid in abdominal cavity, and flows through the temperature of medicinal liquid of heating bag, can accurate detected temperatures.In the self-loopa heating period, after the temperature of the medicinal liquid flowing through heating bag reaches predetermined value, stop heating; At holding stage, detect the temperature flowing into, flow out the medicinal liquid in abdominal cavity, the temperature flowing out the medicinal liquid in abdominal cavity is too high, stops heating, and the temperature flowing into the medicinal liquid in abdominal cavity is too low, starts heating, ensures that medicinal liquid is in temperature required scope, thus precise control of temperature.
Further, threeway comprises the first threeway and the second threeway, pump line comprises the first pump line and the second pump line, and the one or three is common to connection first pump line, the outlet of liquid-collection bag and filter, and the two or three is common to connection second pump line, the entrance of liquid-collection bag and the first temperature-measuring tee joint.
Further, the first pump line and the second pump line are arranged at the two ends of heating bag, avoid heating bag flatulence.
Further, buckle is four.
Further, buckle comprises the first buckle be arranged between liquid-collection bag and the first threeway, be arranged at the second buckle between the first threeway and filter, be arranged at the 3rd buckle between liquid-collection bag and the second threeway, and be arranged at the 4th buckle between the second threeway and the first temperature-measuring tee joint.
Further, treatment stage comprises self-loopa heating period, injection stage, holding stage and emptying recovery stage, and when maintenance first, the 3rd buckle are opened, the second, the 4th buckle is closed, and adjustment circulating pipeline device is adapted to the self-loopa heating period; When maintenance first, the 4th buckle are opened, second, third buckle is closed, and adjustment circulating pipeline device is adapted to the injection stage; When maintenance second, the 4th buckle are opened, the first, the 3rd buckle is closed, and adjustment circulating pipeline device is adapted to holding stage; When second, third buckle of maintenance is opened, the first, the 4th buckle is closed, and adjustment circulating pipeline device is adapted to emptying recovery stage.
Perfusion circulating pipeline device provided by the invention, by the break-make of four buckles, adjustment circulating pipeline device is adapted to different treatment stages.
Further, in heating bag, be provided with the pipeline of three-back-shaped arrangement, make medicine liquid heating more evenly, fast.
Further, liquid-collection bag arranges liquid medicine injection entrance, is convenient to medicinal liquid and injects, easy to operate, can not be mixed into air, ensure therapeutic effect in cyclic process herb liquid.
Further, circulation pipe adopts medical macromolecular materials to make.
Compared with prior art, perfusion circulating pipeline device provided by the invention, has following beneficial effect:
(1) by the break-make of buckle, adjustment circulating pipeline device is adapted to different treatment stages, meets the requirement of abdominal cavity thermotherapy;
(2) use heater plate, system is simple and reliable, to medicinal liquid without destruction;
(3) adopt temperature-measuring tee joint, be convenient to arrange temperature detecting point, accurate detected temperatures and control temperature can be ensured, thus ensure the therapeutic effect of abdominal cavity thermotherapy;
(4) adopt liquid-collection bag, be convenient to medicinal liquid and inject, easy to operate and can not air be mixed in cyclic process herb liquid, ensure therapeutic effect; Medicinal liquid liquid-collection bag is all recycled to after completed treatment, without revealing, environmentally safe;
(5) pump line is configured in heating bag both sides, avoids heating bag flatulence;
(6) arrange filter, effectively can filter out the micro-bolt of tissue, prevent the phenomenon occurring blocking pipeline in cyclic process, circulation is reliable.
Accompanying drawing explanation
Fig. 1 is the structural representation of the perfusion circulating pipeline device of one embodiment of the present of invention.
Detailed description of the invention
Content of the present invention, feature and function is described in detail below in conjunction with Fig. 1.
As shown in Figure 1, the perfusion circulating pipeline device of one embodiment of the present of invention, for abdominal cavity hyperthermia-chemotherapy therapy, comprise circulation pipe, pump line P1, the P2 be arranged on peristaltic pump, liquid-collection bag, is arranged at the heating bag on hot plate, threeway T1, T2, temperature-measuring tee joint S1, S2, S3, filter F and buckle V1, V2, V3, V4, circulation pipe is by female Luer and pump line P1, P2, liquid-collection bag, heating bag, threeway T1, T2, temperature-measuring tee joint S1, S2, S3, filter F is connected; Pump line P1, P2 are used for for medicinal liquid circulation provides power, heating bag is used for for medicine liquid heating, temperature-measuring tee joint S1, S2, S3 are for detecting the temperature of medicinal liquid, and filter F is used for filtering liquid medicine, and buckle V1, V2, V3, V4 are adapted to multiple treatment stage for adjusting circulating pipeline device.
Perfusion circulating pipeline device provided by the invention, by the break-make of buckle V1, V2, V3, V4, adjustment circulating pipeline device is adapted to different treatment stages, meets the requirement of abdominal cavity hyperthermia-chemotherapy therapy; Adopt circulation line and liquid-collection bag, be convenient to recovery and the waste treatment of medicinal liquid; Adopt temperature-measuring tee joint S1, S2, S3, be convenient to arrange temperature detecting point, accurate detected temperatures and control temperature can be ensured, thus ensure the therapeutic effect of abdominal cavity hyperthermia-chemotherapy therapy; Adopt liquid-collection bag, be convenient to medicinal liquid and inject, easy to operate and can not air be mixed in cyclic process herb liquid, ensure therapeutic effect.
Three temperature-measuring tee joints S1, S2, S3 in the present embodiment, temperature-measuring tee joint S1 is for detecting the temperature of the medicinal liquid flowing into abdominal cavity, and temperature-measuring tee joint S2 is for detecting the temperature of the medicinal liquid flowing out abdominal cavity, and temperature-measuring tee joint S3 is for detecting the temperature of the medicinal liquid flowing through heating bag.
Perfusion circulating pipeline device provided by the invention, detects inflow respectively, flows out the temperature of medicinal liquid in abdominal cavity, and flows through the temperature of medicinal liquid of heating bag, can accurate detected temperatures.In the self-loopa heating period, after the temperature of the medicinal liquid flowing through heating bag reaches predetermined value, stop heating; At holding stage, detect the temperature flowing into, flow out the medicinal liquid in abdominal cavity, the temperature flowing out the medicinal liquid in abdominal cavity is too high, stops heating, and the temperature flowing into the medicinal liquid in abdominal cavity is too low, starts heating, ensures that medicinal liquid is in temperature required scope, thus precise control of temperature.
Two threeways T1, T2 in the present embodiment, threeway T1 is for being communicated with the first outlet and filter F of pump line P1, liquid-collection bag, and threeway T2 is for being communicated with the second outlet and temperature-measuring tee joint S1 of pump line P2, liquid-collection bag.
Buckle in the present embodiment is four, and buckle V1 is arranged between liquid-collection bag and threeway T1, and buckle V2 is arranged between threeway T1 and filter F, and buckle V3 is arranged between liquid-collection bag and threeway T2, and buckle V4 is arranged between threeway T2 and temperature-measuring tee joint S1.
The treatment stage of abdominal cavity hyperthermia-chemotherapy therapy comprises self-loopa heating period, injection stage, holding stage and emptying recovery stage, when maintenance buckle V1, buckle V3 open, buckle V2, buckle V4 close, and adjustment circulating pipeline device is adapted to the self-loopa heating period; When maintenance buckle V1, buckle V4 open, buckle V2, buckle V3 close, and adjustment circulating pipeline device is adapted to the injection stage; When maintenance buckle V2, buckle V4 open, buckle V1, buckle V3 close, and adjustment circulating pipeline device is adapted to holding stage; When maintenance buckle V2, buckle V3 open, buckle V1, buckle V4 close, and adjustment circulating pipeline device is adapted to emptying recovery stage.
Perfusion circulating pipeline device in the present embodiment, by the break-make of four buckles V1, V2, V3, V4, adjustment circulating pipeline device is adapted to different treatment stages.
Be provided with the pipeline of three-back-shaped arrangement in heating bag, make medicine liquid heating more evenly, fast.
Heating bag arranges exhaustor Q1, for discharging unnecessary air, ensures therapeutic effect.
Pump line P1,2 is arranged at the two ends of heating bag, avoids heating bag flatulence.
Liquid-collection bag arranges liquid medicine injection incoming interface, is convenient to medicinal liquid and injects, easy to operate, can not be mixed into air, ensure therapeutic effect in cyclic process herb liquid.
Liquid-collection bag arranges exhaustor Q2, for discharging unnecessary air, ensures therapeutic effect.
In temperature-measuring tee joint, critesistor is set, accurately can measures the temperature of medicinal liquid, ensure therapeutic effect.
Circulation pipe adopts medical macromolecular materials to make, and adopts silica gel material to make pump line, respective line and accessory.
As shown in Figure 1, L1, L2, L3, L4, L5, L6, L7, L8, L9 are dismountable female Luer, for connecting circulation pipe and each accessory.
Perfusion circulating pipeline device in the present embodiment, medicinal liquid is injected by the inlet on medicinal liquid liquid-collection bag, is all recycled to medicinal liquid liquid-collection bag after completed treatment, without revealing, environmentally safe; By the opening and closing of configuration buckle V1 to V4, a circuits can realize abdominal cavity hyperthermia-chemotherapy four stage therapeutic process, and equipment is simple and convenient; Medicine liquid heating bag uses heater plate, and system is simple and reliable, to medicinal liquid without destruction; Pump line is configured in medicine liquid heating bag both sides, avoids medicine liquid heating bag flatulence; Be provided with temperature detection interface in pipeline, be convenient to carry out fluid temperature control; Be connected to filter in pipeline, effectively can filter out the micro-bolt of tissue, prevent the phenomenon occurring blocking pipeline in cyclic process, circulation is reliable.
In abdominal cavity hyperthermia-chemotherapy therapy, the specific operation process of the perfusion circulating pipeline device in the present embodiment is as follows:
1, pour into circulating pipeline device to install:
Installed according to the structure shown in Fig. 1 by perfusion circulating pipeline device, screwed by female Luer L1 to L9, be arranged in peristaltic pump by pump line P1, P2, heating bag and hot plate are fitted, and install temperature-sensitive temperature detecting resistance in temperature-measuring tee joint S1, S2, S3.
2, medicinal liquid injects:
Inject medicinal liquid from the inlet liquid-collection bag, wait pending circulation.
3, medicinal liquid self-loopa heating:
Maintenance buckle V1, buckle V3 open, buckle V2, buckle V4 close, start peristaltic pump, start hot plate, medicinal liquid circulates between liquid-collection bag and heating bag, and medicinal liquid is heated when flowing through medicine liquid heating bag, the temperature that temperature-measuring tee joint S3 detects, stop heating after reaching predetermined value, wait for next stage.
4, medicinal liquid injects patient abdominal cavity:
The corresponding opening part in patient abdominal cavity is inserted at the two ends of perfusion circulating pipeline device respectively, and maintenance buckle V1, buckle V4 open, and buckle V2, buckle V3 close, start peristaltic pump, then medicinal liquid enters patient abdominal cavity via heating bag, reaches after medicinal liquid injects volume and stops, waiting for next stage.
5, medicinal liquid soak cycles:
Maintenance buckle V2, buckle V4 open, buckle V1, buckle V3 close, and start peristaltic pump, start hot plate, medicinal liquid circulates between patient abdominal cavity and heating bag via filter F, medicinal liquid is heated when flowing through medicine liquid heating bag, temperature-measuring tee joint S1, S2 detected temperatures, and S2 temperature is too high, stops heating, S1 place temperature is too low, starts heating, ensure that medicinal liquid is in temperature required scope, wait for that this phase treatment terminates, enter next stage.
6, the emptying recovery of medicinal liquid:
Maintenance buckle V2, buckle V3 open, and buckle V1, buckle V4 close, and start peristaltic pump, medicinal liquid is from patient abdominal cavity via filter F, and medicinal liquid is finally collected in liquid-collection bag, terminates whole hyperthermia-chemotherapy therapeutic process after liquid medicine collecting.
Perfusion circulating pipeline device provided by the invention, by selecting the buckle of varying number and being arranged at the diverse location of circulation line, can be used for other abdominal cavity thermotherapys that treatment stage number is different from the present embodiment with requirement.
Perfusion circulating pipeline device provided by the invention, by the break-make of buckle, adjustment circulating pipeline device is adapted to different treatment stages, meets the requirement of abdominal cavity thermotherapy; Use heater plate, system is simple and reliable, to medicinal liquid without destruction; Adopt temperature-measuring tee joint, be convenient to arrange temperature detecting point, accurate detected temperatures and control temperature can be ensured, thus ensure the therapeutic effect of abdominal cavity thermotherapy; Adopt liquid-collection bag, be convenient to medicinal liquid and inject, easy to operate and can not air be mixed in cyclic process herb liquid, ensure therapeutic effect; Medicinal liquid liquid-collection bag is all recycled to after completed treatment, without revealing, environmentally safe; Pump line is configured in heating bag both sides, avoids heating bag flatulence; Arrange filter, effectively can filter out the micro-bolt of tissue, prevent the phenomenon occurring blocking pipeline in cyclic process, circulation is reliable.
More than describe preferred embodiment of the present invention in detail.Should be appreciated that those of ordinary skill in the art just design according to the present invention can make many modifications and variations without the need to creative work.Therefore, all technical staff in the art, all should by the determined protection domain of claims under this invention's idea on the basis of existing technology by the available technical scheme of logical analysis, reasoning, or a limited experiment.
Claims (4)
1. a perfusion circulating pipeline device, for abdominal cavity thermotherapy, it is characterized in that, described circulating pipeline device comprises circulation pipe, the pump line be arranged on peristaltic pump, liquid-collection bag, the heating bag be arranged on hot plate, threeway, temperature-measuring tee joint, filter and buckle, described circulation pipe is connected with described pump line, described liquid-collection bag, described heating bag, described threeway, described temperature-measuring tee joint, described filter by female Luer; Described pump line is used for providing power for the circulation of medicinal liquid, described heating bag is used for for described medicine liquid heating, described temperature-measuring tee joint is for detecting the temperature of described medicinal liquid, and described filter is for filtering described medicinal liquid, and described buckle is adapted to multiple treatment stage for adjusting described circulating pipeline device;
Described temperature-measuring tee joint comprises first, second and the 3rd temperature-measuring tee joint, described first temperature-measuring tee joint is for detecting the temperature of the medicinal liquid flowing into abdominal cavity, described second temperature-measuring tee joint is for detecting the temperature of the medicinal liquid flowing out abdominal cavity, and described 3rd temperature-measuring tee joint is for detecting the temperature of the medicinal liquid flowing through heating bag;
Described threeway comprises the first threeway and the second threeway, described pump line comprises the first pump line and the second pump line, described 1 is common to connection first pump line, the outlet of described liquid-collection bag and described filter, and the described 23 is common to connection second pump line, the entrance of described liquid-collection bag and described first temperature-measuring tee joint;
Described first pump line and described second pump line are arranged at the two ends of described heating bag;
Described buckle comprises the first buckle be arranged between described liquid-collection bag and described first threeway, be arranged at the second buckle between described first threeway and described filter, be arranged at the 3rd buckle between described liquid-collection bag and described second threeway, and be arranged at the 4th buckle between described second threeway and described first temperature-measuring tee joint;
Described treatment stage comprises self-loopa heating period, injection stage, holding stage and emptying recovery stage, when described first, the 3rd buckle of maintenance is opened, described second, the 4th buckle is closed, and adjusts described circulating pipeline device and is adapted to the described self-loopa heating period; When described first, the 4th buckle of maintenance is opened, second, third buckle described is closed, and adjusts described circulating pipeline device and is adapted to the described injection stage; When described second, the 4th buckle of maintenance is opened, described first, the 3rd buckle is closed, and adjusts described circulating pipeline device and is adapted to described holding stage; When maintenance second, third buckle described is opened, described first, the 4th buckle is closed, and adjusts described circulating pipeline device and is adapted to described emptying recovery stage.
2. pour into circulating pipeline device as claimed in claim 1, it is characterized in that, in described heating bag, be provided with the pipeline of three-back-shaped arrangement.
3. pour into circulating pipeline device as claimed in claim 1, it is characterized in that, described liquid-collection bag arranges liquid medicine injection entrance.
4. pour into circulating pipeline device as claimed in claim 1, it is characterized in that, described circulation pipe adopts medical macromolecular materials to make.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410008370.XA CN103751880B (en) | 2014-01-08 | 2014-01-08 | Circulation pipeline device for intraperitoneal chemohyperthermia |
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| CN201410008370.XA CN103751880B (en) | 2014-01-08 | 2014-01-08 | Circulation pipeline device for intraperitoneal chemohyperthermia |
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| CN103751880B true CN103751880B (en) | 2015-12-09 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105727426A (en) * | 2016-01-22 | 2016-07-06 | 深圳迈地海特科技有限公司 | Body cavity hyperthemal perfusion circulating device |
| CN110393627A (en) * | 2019-08-29 | 2019-11-01 | 吉林省迈达医疗器械股份有限公司 | A kind of perfusion unit in use for thermochemical therapeutics for abdominal cavity |
| CN112914818A (en) * | 2021-04-02 | 2021-06-08 | 河南中栋医疗科技有限公司 | Electrical heating abdominal cavity thermal perfusion treatment system |
| CN115089287B (en) * | 2022-06-21 | 2024-05-31 | 河南中栋医疗科技有限公司 | High-precision hot-filling temperature control system |
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| CN1593359A (en) * | 2004-06-24 | 2005-03-16 | 上海交通大学 | Intelligentized radio frequency thermoradiotherapeutic instrument for bladder |
| CN101897636A (en) * | 2010-08-06 | 2010-12-01 | 上海交通大学 | Intraperitoneal hyperthermic perfusion chemotherapy instrument in operation |
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Effective date of registration: 20210111 Address after: 510080 4th floor, building 1, No.1 Keyuan Road, Baiyun District, Guangzhou City, Guangdong Province Patentee after: GUANGZHOU BRIGHT MEDICAL TECHNOLOGY Co.,Ltd. Address before: 200240 No. 800, Dongchuan Road, Shanghai, Minhang District Patentee before: SHANGHAI JIAO TONG University |
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Inventor after: Sheng Xinjun Inventor after: Wang Teng Inventor after: Zhu Xiangyang Inventor after: Yang Qiumeng Inventor after: Huang Diwen Inventor after: Cui Shuzhong Inventor before: Sheng Xinjun Inventor before: Wang Teng Inventor before: Zhu Xiangyang Inventor before: Yang Qiumeng |
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