CN101897636A - Intraperitoneal hyperthermic perfusion chemotherapy instrument in operation - Google Patents
Intraperitoneal hyperthermic perfusion chemotherapy instrument in operation Download PDFInfo
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- CN101897636A CN101897636A CN 201010246182 CN201010246182A CN101897636A CN 101897636 A CN101897636 A CN 101897636A CN 201010246182 CN201010246182 CN 201010246182 CN 201010246182 A CN201010246182 A CN 201010246182A CN 101897636 A CN101897636 A CN 101897636A
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Abstract
The invention discloses an intraperitoneal hyperthermic perfusion chemotherapy instrument in operation, belonging to the technical field of medical instruments. The intraperitoneal hyperthermic perfusion chemotherapy instrument in operation comprises a heating device, a control device, a man-machine interaction device, a chemotherapy liquid collection bag, two adjustable speed peristaltic pumps, two T-junction dividers and a plurality of sensors, wherein the heating device comprises a heating plate and a heating bag, the heating plate and the heating bag are tightly stuck, the heating plate is connected with the control device to transfer heating temperature control information, and the inlet and the outlet of the heating bag are respectively provided with a temperature sensor. The invention has simple structure and convenient operation; the heating plate is utilized to carry out heat exchange so as to evenly heat, and the chemotherapy liquid is only sealed and circulated in the pipeline, which is clean and reliable; and the chemotherapy liquid collection bag can effectively collect and manage the chemotherapy liquid, and a DSP processor has precise temperature control and obvious curative effect.
Description
Technical field
What the present invention relates to is a kind of device of Medical Instruments technical field, specifically is a kind of warm chemotherapy instrument in art abdominal cavity that is used for the abdominal cavity treating malignant tumor.
Background technology
The warm chemotherapy of intraperitoneal is utilized regional high-dose chemotherapy and warm synergism in the art, induces intraperitoneal tumor cell generation apoptosis and necrosis, and its clinical efficacy has obtained certainly.Yet, do not obtain ideal solution for the heated at constant temperature of chemotherapy liquid yet.
Find through retrieval the prior art document, Chinese patent application number is: 200820104050.4, publication number is: CN201157449Y, name is called " body cavity continues the circulation thermal therapeutic apparatus ", this technology readme is: adopt the pump line system of circulating pump to connect puncture and intubation by heating back in the thermostatic water tank, the water inlet pipe and water outlet pipe of described puncture and intubation is provided with temperature sensor and display, and described temperature sensor connects temperature controller.This kind technology has solved chemotherapy liquid heating problems, but its temperature-controlled precision and response speed are undesirable, and medicinal liquid inconvenience is reclaimed.
Find by retrieval that in addition Chinese patent application number be 200410011166.X, publication number is: CN 1600284A, and name is called " thermochemotherapy perfusion unit ", and this technology is used the heating of microwave heating source realization to chemotherapy liquid.But this technology utilizes the microwave heating structure that chemotherapy liquid is damaged, and has disturbed therapeutic effect.
In addition, the Medical Instruments of this kind of prior art therapy, its technology adopts heat exchange tank, heat-exchange tube and liquid storage container more, though solved heating and chemotherapy liquid collection problem, but following shortcoming is arranged: one, chemotherapy hydraulic control temperature precision is undesirable, the slow and monitoring temperature variation in real time of temperature-responsive; Two, chemotherapy liquid is stored in the container, is unfavorable for its collection and waste treatment, also makes troubles for the health storage and the instrument cleaning of chemotherapy liquid.
Summary of the invention
The objective of the invention is to overcome above-mentioned deficiency of the prior art, the warm chemotherapy instrument in abdominal cavity in a kind of art is provided.The present invention can realize the even heating of chemotherapy liquid in the art and effectively collect, and guarantees therapeutic effect, and it is convenient to make that postoperative reclaims.
The present invention is achieved by the following technical solutions:
The present invention includes: heater, control device, human-computer interaction device, chemotherapy liquid collecting bag, two adjustable speed peristaltic pumps, two three-way shunts and some temperature sensors, wherein: an end of heater links to each other with the first adjustable speed peristaltic pump, the first adjustable speed peristaltic pump links to each other with chemotherapy liquid collecting bag, chemotherapy liquid collecting bag links to each other with the second adjustable speed peristaltic pump, the second adjustable speed peristaltic pump links to each other with second three-way shunt, the other end of heater links to each other with first three-way shunt, two three-way shunts inject the abdominal cavity respectively, temperature sensor is separately positioned on the import of heater, the outlet of heater, advance the abdominal cavity mouth, go out abdominal cavity mouth and abdominal cavity, heater links to each other with control device and transmits heating-up temperature and heating and temperature control information, two adjustable speed peristaltic pumps link to each other with control device respectively and transmit peristaltic velocity and peristaltic velocity control information, and control device links to each other with human-computer interaction device and transmits control information, temperature information and peristaltic pump peristaltic velocity information.
Described control device links to each other with stand-by power supply.
Described temperature sensor is provided with the bridge circuit amplifier.
Described heater comprises: hot plate and heating bag, and wherein: hot plate and heating bag fit tightly, and hot plate links to each other with control device and transmits heating and temperature control information, and the entrance and exit of heating bag is respectively arranged with temperature sensor.
Be provided with the pipeline that complications are arranged in the described heating bag.
Described control device comprises: DSP (Digital Signal Processing, Digital Signal Processing), SCI (serial communication interface, serial communication interface) interface, GPI (General Purpose Interface, general-purpose interface) interface, PWM (Pulse Width Modulation, pulse width modulation) controller, digital to analog converter and analog-digital converter, wherein: an end of SCI interface links to each other with DSP and transmits control information, temperature information and peristaltic pump peristaltic velocity information, the control information that links to each other with human-computer interaction device of the other end of SCI interface, temperature information and peristaltic pump peristaltic velocity information, the transportation simulator control information that links to each other with analog-digital converter of one end of GPI interface, the analog-digital converter transmission of digital control information that links to each other with temperature sensor, the transportation simulator control information that links to each other with DSP of the other end of GPI interface, the input of PWM controller links to each other with DSP and transmits temperature control information, the outfan of PWM controller links to each other with heater and transmits temperature control information, the input of digital to analog converter links to each other with DSP and transmits peristaltic velocity control figure information, and the outfan of digital to analog converter links to each other with the adjustable speed peristaltic pump and transmits peristaltic velocity control analog information.
Compared with prior art, beneficial effect of the present invention is:
1, by the temperature of control hot plate, make the interior chemotherapy liquid of heating bag can accurately be controlled at 43 ℃ ± 1 ℃, temperature-responsive is fast, heating accuracy height, and periodic duty for a long time;
2, chemotherapy liquid recycles, and only contacts with patient abdominal cavity and disposable tubing all the time, has avoided the pollution hidden trouble of chemotherapy liquid, also makes the very convenient health of collection of postoperative chemotherapy liquid;
3, temperature control is accurate, and the monitoring of multi way temperature pick off makes the doctor can understand real-time condition everywhere, is convenient to take corresponding measure;
4, this device is easy to operate in addition, and emergency measure is perfect, the reliable advantage of health.
Description of drawings
Fig. 1 is the composition connection diagram of apparatus of the present invention;
Wherein: 1-heating bag, 2-hot plate, the 3-first adjustable speed peristaltic pump, 4-chemotherapy liquid collecting bag, the 5-second adjustable speed peristaltic pump, 6-second three-way shunt, 7-abdominal cavity, 8-first three-way shunt, 9-control device, 10-temperature sensor, 11-human-computer interaction device.
The specific embodiment
Below in conjunction with accompanying drawing device of the present invention is further described: present embodiment is being to implement under the prerequisite with the technical solution of the present invention, provided detailed embodiment and concrete operating process, but protection scope of the present invention is not limited to following embodiment.
Embodiment
As shown in Figure 1, present embodiment comprises: heater, control device 9, human-computer interaction device 11, chemotherapy liquid collecting bag 4, the first adjustable speed peristaltic pump 3, the second adjustable speed peristaltic pump 5, first three-way shunt 8, second three-way shunt 6, with seven temperature sensors 10, wherein: an end of heater links to each other with the first adjustable speed peristaltic pump 3, the first adjustable speed peristaltic pump 3 links to each other with chemotherapy liquid collecting bag 4, chemotherapy liquid collecting bag 4 links to each other with the second adjustable speed peristaltic pump 5, the second adjustable speed peristaltic pump 5 links to each other with second three-way shunt 6, the other end of heater links to each other with first three-way shunt 8, two three-way shunts inject abdominal cavity 7 respectively, first temperature sensor is arranged on the import of heater, second temperature sensor is arranged on the outlet of heater, three-temperature sensor is arranged on into abdominal cavity mouth, the 4th temperature sensor is arranged on out the abdominal cavity mouth, the 5th temperature sensor, the 6th temperature sensor and the 7th temperature sensor are separately positioned in the abdominal cavity 7, heater links to each other with control device 9 and transmits heating-up temperature and heating and temperature control information, the first adjustable speed peristaltic pump 3 links to each other with control device 9 respectively with the second adjustable speed peristaltic pump 5 and transmits peristaltic velocity and peristaltic velocity control information, and control device 9 links to each other with human-computer interaction device 11 and transmits control information, temperature information and peristaltic pump peristaltic velocity information.
Described human-computer interaction device 11 is computers.
Described temperature sensor 10 is provided with the bridge circuit amplifier, passes to control device 9 after the temperature signal that this bridge circuit amplifier obtains temperature sensor 10 amplifies.
Described control device 9 links to each other with stand-by power supply, and this stand-by power supply can guarantee whole device working time of in case of emergency 90 minutes.
Described heater comprises: hot plate 2 and heating bag 1, wherein: hot plate 2 and heating bag 1 fit tightly, hot plate 2 links to each other with control device 9 and transmits heating and temperature control information, the entrance and exit of heating bag 1 is respectively arranged with temperature sensor, and temperature sensor links to each other with control device 9 and transmits heating-up temperature information.
What described hot plate 2 adopted is bidirectional triode thyristor drive circuit of the prior art.
Be provided with the pipeline that complications are arranged in the described heating bag 1, the chemotherapy liquid stream is crooked mobile because the complications in the heating bag 1 are arranged when heating bag 1, makes every effort to prolong the time of staying in bag, and then obtains sufficient heat exchange.
The range of flow of the described first adjustable speed peristaltic pump 3 and the second adjustable speed peristaltic pump 5 all is: 800ml/min-900ml/min.
Described control device 9 comprises: DSP, the SCI interface, the GPI interface, the PWM controller, digital to analog converter and analog-digital converter, wherein: an end of SCI interface links to each other with DSP and transmits control information, temperature information and peristaltic pump peristaltic velocity information, the control information that links to each other with human-computer interaction device of the other end of SCI interface, temperature information and peristaltic pump peristaltic velocity information, the transportation simulator control information that links to each other with analog-digital converter of one end of GPI interface, the analog-digital converter transmission of digital control information that links to each other with temperature sensor, the transportation simulator control information that links to each other with DSP of the other end of GPI interface, the input of PWM controller links to each other with DSP and transmits temperature control information, the outfan of PWM controller links to each other with heater and transmits temperature control information, the input of digital to analog converter links to each other with DSP and transmits peristaltic velocity control figure information, and the outfan of digital to analog converter links to each other with the second adjustable speed peristaltic pump 5 with the first adjustable speed peristaltic pump 3 respectively and transmits peristaltic velocity control analog information.
What the DSP in the present embodiment adopted is the F2812 chip.
The work process of present embodiment: two adjustable speed peristaltic pumps provide circulation power for chemotherapy liquid, chemotherapy liquid collecting bag 4 is realized in the chemotherapy liquid input body or chemotherapy liquid in the emptying body by the rotating speed control to two adjustable speed peristaltic pumps between two adjustable speed peristaltic pumps; Chemotherapy liquid flows into heating bag 1 by the road, and heating bag 1 is fitted with hot plate 2, and DSP heats up by the heat passage chemotherapy liquid that flows through in the heating bag 1 that makes, thereby is controlled at 43 ℃ ± 1 ℃ by the heating-up temperature of PID method control hot plate 2; Chemotherapy liquid after the heating flows into abdominal cavities 7 through first three-way shunt 8, and second three-way shunt 6 of 7 other ends flows out abdominal cavities 7 through the abdominal cavity; Advance the abdominal cavity mouth, go out in abdominal cavity mouth and the abdominal cavity 7 all to be furnished with temperature sensor, the output signal of these temperature sensors inserts the analog-digital converter of DSP after amplifying.According to these temperature signals, can monitor patient in the art in real time on the one hand, DSP can control the peristaltic velocity information of hot plate 2 and two adjustable speed peristaltic pumps according to temperature information on the other hand, thereby chemotherapy liquid is controlled at about 43 ℃ all the time.
When the second adjustable speed peristaltic pump 5 quits work and during the first adjustable speed peristaltic pump, 3 operate as normal, chemotherapy liquid input abdominal cavity 7 in this device; When the second adjustable speed peristaltic pump 5 and the first adjustable speed peristaltic pump 3 during simultaneously with the speed running, the chemotherapy liquid in this device is for circulating; When the second adjustable speed peristaltic pump, 5 operate as normal and the first adjustable speed peristaltic pump 3 quit work, the chemotherapy liquid in this device was discharged abdominal cavity 7, finally enters chemotherapy liquid collecting bag 4.
Present embodiment is simple in structure, and is easy to operate, utilizes hot plate to carry out the heat exchange homogeneous heating, and only in the circulation of pipeline inner sealing, health is reliable for chemotherapy liquid, adopts effectively collection management chemotherapy liquid of chemotherapy liquid collecting bag; Utilize the dsp processor temperature control accurate, evident in efficacy.
Claims (7)
1. the warm chemotherapy instrument in abdominal cavity in the art, comprise: heater, control device, human-computer interaction device, two adjustable speed peristaltic pumps, two three-way shunts and some temperature sensors, it is characterized in that, also comprise: chemotherapy liquid collecting bag, wherein: an end of heater links to each other with the first adjustable speed peristaltic pump, the first adjustable speed peristaltic pump links to each other with chemotherapy liquid collecting bag, chemotherapy liquid collecting bag links to each other with the second adjustable speed peristaltic pump, the second adjustable speed peristaltic pump links to each other with second three-way shunt, the other end of heater links to each other with first three-way shunt, two three-way shunts inject the abdominal cavity respectively, temperature sensor is separately positioned on the import of heater, the outlet of heater, advance the abdominal cavity mouth, go out abdominal cavity mouth and abdominal cavity, heater links to each other with control device and transmits heating-up temperature and heating and temperature control information, two adjustable speed peristaltic pumps link to each other with control device respectively and transmit peristaltic velocity and peristaltic velocity control information, and control device links to each other with human-computer interaction device and transmits control information, temperature information and peristaltic pump peristaltic velocity information.
2. the warm chemotherapy instrument in abdominal cavity is characterized in that in the art according to claim 1, and described control device links to each other with stand-by power supply.
3. according to the warm chemotherapy instrument in abdominal cavity in claim 1 or the 2 described arts, it is characterized in that, described control device comprises: DSP, the SCI interface, the GPI interface, the PWM controller, digital to analog converter and analog-digital converter, wherein: an end of SCI interface links to each other with DSP and transmits control information, temperature information and peristaltic pump peristaltic velocity information, the control information that links to each other with human-computer interaction device of the other end of SCI interface, temperature information and peristaltic pump peristaltic velocity information, the transportation simulator control information that links to each other with analog-digital converter of one end of GPI interface, the analog-digital converter transmission of digital control information that links to each other with temperature sensor, the transportation simulator control information that links to each other with DSP of the other end of GPI interface, the input of PWM controller links to each other with DSP and transmits temperature control information, the outfan of PWM controller links to each other with heater and transmits temperature control information, the input of digital to analog converter links to each other with DSP and transmits peristaltic velocity control figure information, and the outfan of digital to analog converter links to each other with the adjustable speed peristaltic pump and transmits peristaltic velocity control analog information.
4. the warm chemotherapy instrument in abdominal cavity in the art according to claim 1, it is characterized in that, described heater comprises: hot plate and heating bag, wherein: hot plate and heating bag fit tightly, hot plate links to each other with control device and transmits heating and temperature control information, and the entrance and exit of heating bag is respectively arranged with temperature sensor.
5. the warm chemotherapy instrument in abdominal cavity is characterized in that in the art according to claim 4, and what described hot plate adopted is the bidirectional triode thyristor drive circuit.
6. the warm chemotherapy instrument in abdominal cavity is characterized in that in the art according to claim 4, is provided with the pipeline that complications are arranged in the described heating bag.
7. the warm chemotherapy instrument in abdominal cavity is characterized in that in the art according to claim 1, and described temperature sensor is provided with the bridge circuit amplifier.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102461822A CN101897636B (en) | 2010-08-06 | 2010-08-06 | Intraperitoneal hyperthermic perfusion chemotherapy instrument in operation |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102461822A CN101897636B (en) | 2010-08-06 | 2010-08-06 | Intraperitoneal hyperthermic perfusion chemotherapy instrument in operation |
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| CN101897636A true CN101897636A (en) | 2010-12-01 |
| CN101897636B CN101897636B (en) | 2012-08-22 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751880A (en) * | 2014-01-08 | 2014-04-30 | 上海交通大学 | Circulation pipeline device for intraperitoneal chemohyperthermia |
| CN109893334A (en) * | 2019-04-29 | 2019-06-18 | 河南中医药大学 | Abdominal thermal infusion chemotherapy device |
| CN110393627A (en) * | 2019-08-29 | 2019-11-01 | 吉林省迈达医疗器械股份有限公司 | A kind of perfusion unit in use for thermochemical therapeutics for abdominal cavity |
| CN116763531A (en) * | 2021-05-25 | 2023-09-19 | 朱晓丹 | Organ rewarming device for organ transplantation and control method thereof |
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| EP0801938A2 (en) * | 1996-04-16 | 1997-10-22 | ARGOMED Ltd. | Thermal treatment apparatus |
| CN2740197Y (en) * | 2004-06-22 | 2005-11-16 | 杨骏成 | Circulation thermochemical therapeutic pouring device of abdominal cavity |
| CN2808181Y (en) * | 2005-07-14 | 2006-08-23 | 上海涌泉医疗科技发展有限公司 | Heating and flow-assistant apparatus for heat therapy and chemical therapy |
| CN101120891A (en) * | 2007-07-25 | 2008-02-13 | 程海宇 | Multifunctional tumor insertion thermotherapy machine |
| CN101744682A (en) * | 2009-06-24 | 2010-06-23 | 中国科学院自动化研究所 | Intravascular automatic temperature regulation instrument |
| CN201529291U (en) * | 2009-09-14 | 2010-07-21 | 曹淑琴 | Intelligent constant-temperature transfusion heater |
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2010
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP0801938A2 (en) * | 1996-04-16 | 1997-10-22 | ARGOMED Ltd. | Thermal treatment apparatus |
| CN2740197Y (en) * | 2004-06-22 | 2005-11-16 | 杨骏成 | Circulation thermochemical therapeutic pouring device of abdominal cavity |
| CN2808181Y (en) * | 2005-07-14 | 2006-08-23 | 上海涌泉医疗科技发展有限公司 | Heating and flow-assistant apparatus for heat therapy and chemical therapy |
| CN101120891A (en) * | 2007-07-25 | 2008-02-13 | 程海宇 | Multifunctional tumor insertion thermotherapy machine |
| CN101744682A (en) * | 2009-06-24 | 2010-06-23 | 中国科学院自动化研究所 | Intravascular automatic temperature regulation instrument |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751880A (en) * | 2014-01-08 | 2014-04-30 | 上海交通大学 | Circulation pipeline device for intraperitoneal chemohyperthermia |
| CN103751880B (en) * | 2014-01-08 | 2015-12-09 | 上海交通大学 | Circulation pipeline device for intraperitoneal chemohyperthermia |
| CN109893334A (en) * | 2019-04-29 | 2019-06-18 | 河南中医药大学 | Abdominal thermal infusion chemotherapy device |
| CN109893334B (en) * | 2019-04-29 | 2020-12-25 | 河南中医药大学 | Abdominal cavity heat perfusion chemotherapy device |
| CN110393627A (en) * | 2019-08-29 | 2019-11-01 | 吉林省迈达医疗器械股份有限公司 | A kind of perfusion unit in use for thermochemical therapeutics for abdominal cavity |
| CN116763531A (en) * | 2021-05-25 | 2023-09-19 | 朱晓丹 | Organ rewarming device for organ transplantation and control method thereof |
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| CN101897636B (en) | 2012-08-22 |
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Effective date of registration: 20210111 Address after: 510080 4th floor, building 1, No.1 Keyuan Road, Baiyun District, Guangzhou City, Guangdong Province Patentee after: GUANGZHOU BRIGHT MEDICAL TECHNOLOGY Co.,Ltd. Address before: 200240 No. 800, Dongchuan Road, Shanghai, Minhang District Patentee before: SHANGHAI JIAO TONG University |
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Inventor after: Fu Yan Ling Inventor after: Zhu Xiangyang Inventor after: Yang Qiumeng Inventor after: Sheng Xinjun Inventor after: Huang Diwen Inventor after: Cui Shuzhong Inventor before: Fu Yan Ling Inventor before: Zhu Xiangyang Inventor before: Yang Qiumeng Inventor before: Sheng Xinjun |