CN103751880A - Circulation pipeline device for intraperitoneal chemohyperthermia - Google Patents
Circulation pipeline device for intraperitoneal chemohyperthermia Download PDFInfo
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- CN103751880A CN103751880A CN201410008370.XA CN201410008370A CN103751880A CN 103751880 A CN103751880 A CN 103751880A CN 201410008370 A CN201410008370 A CN 201410008370A CN 103751880 A CN103751880 A CN 103751880A
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Abstract
The invention provides a chemohyperthermia circulation pipeline device for intraperitoneal chemohyperthermia. The circulation pipeline device is adjusted to adapt to different therapy periods by on and off of clips to meet requirements of the intraperitoneal chemohyperthermia. System simplicity and reliability can be achieved while liquid medicine is undamaged by using heating plates for heating. Using a temperature tee joint is convenient for arrangement of temperature detection points and can guarantee precision in temperature detection and control so as to guarantee therapeutic effects of the intraperitoneal chemohyperthermia. Using a liquid collection bag is convenient for infusion of liquid medicine and convenient to operate, and air is prevented from being mixed in the liquid medicine during circulation, so that therapeutic effects can be guaranteed. The liquid medicine is completely recovered to the liquid collection bag after therapy, and leakage and environment pollution are prevented. Pump pipes are arranged on two sides of a heating bag to avoid inflation of the heating bag. Human tissue microemboli can be effectively filtered by a filter to prevent pipeline blocking during circulation, so that reliability in circulation is realized.
Description
Technical field
The invention belongs to medical assistance instrument field, specifically a kind of medicinal liquid filling circulating pipeline device for abdominal cavity thermotherapy.
Background technology
Abdominal cavity thermotherapy utilizes the synergism of regional heavy dose of thermotherapy and chemotherapy, by heat-therapeutic action, kill cancerous cell and directly kill cancerous cell by Chemotherapy, mechanically by coming off, in the free cancerous cell of intraperitoneal, rinse out simultaneously, its effectiveness obtains a large amount of clinical trials and confirms, the more and more first-selected therapeutic scheme for treatment belly cavity tumor by approval, but there is in the following areas defect and inconvenience in the existing perfusion circulating pipeline device based on abdominal cavity hyperthermia-chemotherapy therapy at present:
1, hyperthermia-chemotherapy before this adopts water-bath mode conventionally, and pipeline is simple, is difficult to realize accurate temperature controlling, cannot reach the effect of hyperthermia-chemotherapy;
2, circulation line poor reliability, the flow process complexity such as medicinal liquid filling, inconvenient operation; And easy entrained air in cyclic process herb liquid, is difficult to remove, and affects chemotherapy effect;
3, temperature detecting point complicated layout in cyclic process, is difficult to detect, and temperature control precision is difficult to guarantee;
4, adopt heat exchange tank, the equipment such as heat-exchange tube, the recovery of medicinal liquid and waste treatment inconvenience.
Summary of the invention
The problem existing for existing perfusion circulating pipeline device, the invention provides a kind of perfusion circulating pipeline device, for abdominal cavity thermotherapy.
Perfusion circulating pipeline device provided by the invention, for abdominal cavity thermotherapy, comprise circulation pipe, be arranged at pump line, liquid-collection bag on peristaltic pump, be arranged at heating bag, threeway, temperature-measuring tee joint, filter and buckle on hot plate, circulation pipe is connected with pump line, liquid-collection bag, heating bag, threeway, temperature-measuring tee joint, filter by female Luer; Pump line is used to medicinal liquid circulation that power is provided, and heating bag is used to medicine liquid heating, and temperature-measuring tee joint is for detection of the temperature of medicinal liquid, and filter is for filtering liquid medicine, and buckle is used for adjusting circulating pipeline device and is adapted to multiple treatment stages.
Perfusion circulating pipeline device provided by the invention, by the break-make of buckle, adjusts circulating pipeline device and is adapted to different treatment stages, meets the requirement of abdominal cavity thermotherapy; Adopt circulation line and liquid-collection bag, be convenient to recovery and the waste treatment of medicinal liquid; Adopt temperature-measuring tee joint, be convenient to arrange temperature detecting point, can guarantee accurate detected temperatures and control temperature, thereby guarantee the therapeutic effect of abdominal cavity thermotherapy; Adopt liquid-collection bag, be convenient to medicinal liquid and inject, can entrained air in easy to operate and cyclic process herb liquid, guarantee therapeutic effect.
Further, temperature-measuring tee joint comprises first, second and the 3rd temperature-measuring tee joint, the first temperature-measuring tee joint is for detection of the temperature of the medicinal liquid in inflow abdominal cavity, and the second temperature-measuring tee joint is for detection of the temperature of the medicinal liquid in outflow abdominal cavity, and the 3rd temperature-measuring tee joint is for detection of the temperature of the medicinal liquid of the heating bag of flowing through.
Perfusion circulating pipeline device provided by the invention, detects respectively the temperature that flows into, flows out the medicinal liquid in abdominal cavity, and the temperature of the medicinal liquid of the heating bag of flowing through, accurately detected temperatures.In the self-loopa heating period, after reaching predetermined value, the temperature of the medicinal liquid of the heating bag of flowing through stops heating; At holding stage, detect the temperature of medicinal liquid that flows into, flows out abdominal cavity, the excess Temperature that flows out the medicinal liquid in abdominal cavity stops heating, flows into that the temperature of medicinal liquid in abdominal cavity is too low starts heating, guarantees that medicinal liquid is in temperature required scope, thereby accurately controls temperature.
Further, threeway comprises the first threeway and the second threeway, pump line comprises the first pump line and the second pump line, and the one or three is common to the outlet and the filter that are communicated with the first pump line, liquid-collection bag, and the two or three is common to the entrance and the first temperature-measuring tee joint that are communicated with the second pump line, liquid-collection bag.
Further, the first pump line and the second pump line are arranged at the two ends of heating bag, avoid heating bag flatulence.
Further, buckle is four.
Further, buckle comprises the first buckle being arranged between liquid-collection bag and the first threeway, be arranged at the second buckle between the first threeway and filter, be arranged at the 3rd buckle between liquid-collection bag and the second threeway, and be arranged at the 4th buckle between the second threeway and the first temperature-measuring tee joint.
Further, treatment stage comprises self-loopa heating period, injection stage, holding stage and emptying recovery stage, when keeping first, the 3rd buckle opens, and second, the 4th buckle closes, adjust circulating pipeline device and be adapted to the self-loopa heating period; When maintenance first, the 4th buckle, open, second, third buckle is closed, and adjusts circulating pipeline device and is adapted to the injection stage; When keeping second, the 4th buckle opens, first, the 3rd buckle closes, adjust circulating pipeline device and be adapted to holding stage; When keeping second, third buckle to open, first, the 4th buckle closes, adjust circulating pipeline device and be adapted to emptying recovery stage.
Perfusion circulating pipeline device provided by the invention, by the break-make of four buckles, adjusts circulating pipeline device and is adapted to different treatment stages.
Further, in heating bag, be provided with three-back-shaped pipeline of arranging, make medicine liquid heating more evenly, fast.
Further, liquid-collection bag arranges liquid medicine injection entrance, is convenient to medicinal liquid and injects, easy to operate, can entrained air in cyclic process herb liquid, guarantee therapeutic effect.
Further, circulation pipe adopts medical macromolecular materials to make.
Compared with prior art, perfusion circulating pipeline device provided by the invention, has following beneficial effect:
(1) by the break-make of buckle, adjust circulating pipeline device and be adapted to different treatment stages, meet the requirement of abdominal cavity thermotherapy;
(2) use hot plate heating, system is simple and reliable, to medicinal liquid without destruction;
(3) adopt temperature-measuring tee joint, be convenient to arrange temperature detecting point, can guarantee accurate detected temperatures and control temperature, thereby guarantee the therapeutic effect of abdominal cavity thermotherapy;
(4) adopt liquid-collection bag, be convenient to medicinal liquid and inject, can entrained air in easy to operate and cyclic process herb liquid, guarantee therapeutic effect; After completed treatment, be all recycled to medicinal liquid liquid-collection bag, without revealing, environmentally safe;
(5) pump line is configured in heating bag both sides, avoids heating bag flatulence;
(6) filter is set, can effectively filters out the micro-bolt of tissue, prevent from occurring in cyclic process the phenomenon of blocking pipeline, circulation is reliable.
Accompanying drawing explanation
Fig. 1 is the structural representation of the perfusion circulating pipeline device of one embodiment of the present of invention.
The specific embodiment
Below in conjunction with Fig. 1, describe content of the present invention, feature and function in detail.
As shown in Figure 1, the perfusion circulating pipeline device of one embodiment of the present of invention, for abdominal cavity hyperthermia-chemotherapy therapy, comprise circulation pipe, be arranged at pump line P1, P2 on peristaltic pump, liquid-collection bag, is arranged at the heating bag on hot plate, threeway T1, T2, temperature-measuring tee joint S1, S2, S3, filter F and buckle V1, V2, V3, V4, circulation pipe is by female Luer and pump line P1, P2, liquid-collection bag, heating bag, threeway T1, T2, temperature-measuring tee joint S1, S2, S3, filter F is connected; Pump line P1, P2 are used to medicinal liquid circulation that power is provided, heating bag is used to medicine liquid heating, temperature-measuring tee joint S1, S2, S3 are for detection of the temperature of medicinal liquid, and filter F is for filtering liquid medicine, and buckle V1, V2, V3, V4 are used for adjusting circulating pipeline device and are adapted to multiple treatment stages.
Perfusion circulating pipeline device provided by the invention, by the break-make of buckle V1, V2, V3, V4, adjusts circulating pipeline device and is adapted to different treatment stages, meets the requirement of abdominal cavity hyperthermia-chemotherapy therapy; Adopt circulation line and liquid-collection bag, be convenient to recovery and the waste treatment of medicinal liquid; Adopt temperature-measuring tee joint S1, S2, S3, be convenient to arrange temperature detecting point, can guarantee accurate detected temperatures and control temperature, thereby guarantee the therapeutic effect of abdominal cavity hyperthermia-chemotherapy therapy; Adopt liquid-collection bag, be convenient to medicinal liquid and inject, can entrained air in easy to operate and cyclic process herb liquid, guarantee therapeutic effect.
Three temperature-measuring tee joint S1, S2 in the present embodiment, S3, temperature-measuring tee joint S1 is for detection of the temperature of the medicinal liquid in inflow abdominal cavity, and temperature-measuring tee joint S2 is for detection of the temperature of the medicinal liquid in outflow abdominal cavity, and temperature-measuring tee joint S3 is for detection of the temperature of the medicinal liquid of the heating bag of flowing through.
Perfusion circulating pipeline device provided by the invention, detects respectively the temperature that flows into, flows out the medicinal liquid in abdominal cavity, and the temperature of the medicinal liquid of the heating bag of flowing through, accurately detected temperatures.In the self-loopa heating period, after reaching predetermined value, the temperature of the medicinal liquid of the heating bag of flowing through stops heating; At holding stage, detect the temperature of medicinal liquid that flows into, flows out abdominal cavity, the excess Temperature that flows out the medicinal liquid in abdominal cavity stops heating, flows into that the temperature of medicinal liquid in abdominal cavity is too low starts heating, guarantees that medicinal liquid is in temperature required scope, thereby accurately controls temperature.
Two threeway T1, T2 in the present embodiment, threeway T1 is for being communicated with the first outlet and filter F of pump line P1, liquid-collection bag, and threeway T2 is for being communicated with the second outlet and temperature-measuring tee joint S1 of pump line P2, liquid-collection bag.
Buckle in the present embodiment is four, and buckle V1 is arranged between liquid-collection bag and threeway T1, and buckle V2 is arranged between threeway T1 and filter F, and buckle V3 is arranged between liquid-collection bag and threeway T2, and buckle V4 is arranged between threeway T2 and temperature-measuring tee joint S1.
The treatment stage of abdominal cavity hyperthermia-chemotherapy therapy comprises self-loopa heating period, injection stage, holding stage and emptying recovery stage, when keeping buckle V1, buckle V3 to open, buckle V2, buckle V4 close, and adjust circulating pipeline device and are adapted to the self-loopa heating period; When keeping buckle V1, buckle V4 to open, buckle V2, buckle V3 close, and adjust circulating pipeline device and are adapted to the injection stage; When keeping buckle V2, buckle V4 to open, buckle V1, buckle V3 close, and adjust circulating pipeline device and are adapted to holding stage; When keeping buckle V2, buckle V3 to open, buckle V1, buckle V4 close, and adjust circulating pipeline device and are adapted to emptying recovery stage.
Perfusion circulating pipeline device in the present embodiment, by the break-make of four buckle V1, V2, V3, V4, adjusts circulating pipeline device and is adapted to different treatment stages.
In heating bag, be provided with three-back-shaped pipeline of arranging, make medicine liquid heating more evenly, fast.
Heating bag arranges exhaustor Q1, for discharging unnecessary air, guarantees therapeutic effect.
Pump line P1,2 is arranged at the two ends of heating bag, avoids heating bag flatulence.
Liquid-collection bag arranges liquid medicine injection incoming interface, is convenient to medicinal liquid and injects, easy to operate, can entrained air in cyclic process herb liquid, guarantee therapeutic effect.
Liquid-collection bag arranges exhaustor Q2, for discharging unnecessary air, guarantees therapeutic effect.
Critesistor is set in temperature-measuring tee joint, can accurately measures the temperature of medicinal liquid, guarantee therapeutic effect.
Circulation pipe adopts medical macromolecular materials to make, and adopts silica gel material to make pump line, respective line and accessory.
As shown in Figure 1, L1, L2, L3, L4, L5, L6, L7, L8, L9 are dismountable female Luer, for connecting circulation pipe and each accessory.
Perfusion circulating pipeline device in the present embodiment, medicinal liquid injects by the inlet on medicinal liquid liquid-collection bag, is all recycled to medicinal liquid liquid-collection bag after completed treatment, without revealing, environmentally safe; Switching by configuration buckle V1 to V4, a circuits can realize abdominal cavity hyperthermia-chemotherapy quadravalence section therapeutic process, and equipment is simple and convenient; Medicine liquid heating bag is used hot plate heating, and system is simple and reliable, to medicinal liquid without destruction; Pump line is configured in medicine liquid heating bag both sides, avoids medicine liquid heating bag flatulence; In pipeline, be provided with temperature detection interface, be convenient to carry out fluid temperature control; In pipeline, be connected to filter, can effectively filter out the micro-bolt of tissue, prevent from occurring in cyclic process the phenomenon of blocking pipeline, circulation is reliable.
In abdominal cavity hyperthermia-chemotherapy therapy, the specific operation process of the perfusion circulating pipeline device in the present embodiment is as follows:
1, perfusion circulating pipeline device is installed:
Perfusion circulating pipeline device is installed according to the structure shown in Fig. 1, female Luer L1 is screwed to L9, pump line P1, P2 are arranged in peristaltic pump, heating bag and hot plate laminating, install temperature-sensitive temperature detecting resistance in temperature-measuring tee joint S1, S2, S3.
2, medicinal liquid injects:
Inlet from liquid-collection bag injects medicinal liquid, waits pending circulation.
3, medicinal liquid self-loopa heating:
Keep buckle V1, buckle V3 to open, buckle V2, buckle V4 close, start peristaltic pump, start hot plate, medicinal liquid circulates between liquid-collection bag and heating bag, and medicinal liquid is heated when flowing through medicine liquid heating bag, the temperature that temperature-measuring tee joint S3 detects, after reaching predetermined value, stop heating, wait for next stage.
4, medicinal liquid injects patient abdominal cavity:
The corresponding opening part in patient abdominal cavity is inserted respectively in the two ends of perfusion circulating pipeline device, keep buckle V1, buckle V4 to open, buckle V2, buckle V3 close, start peristaltic pump, medicinal liquid enters patient abdominal cavity via heating bag, reaches after medicinal liquid injects volume and stops, and waits for next stage.
5, medicinal liquid insulation circulation:
Keep buckle V2, buckle V4 to open, buckle V1, buckle V3 close, and start peristaltic pump, start hot plate, medicinal liquid circulates between patient abdominal cavity and heating bag via filter F, medicinal liquid is heated when flowing through medicine liquid heating bag, temperature-measuring tee joint S1, S2 detected temperatures, and S2 excess Temperature stops heating, S1 place temperature heats by too low beginning, guarantee that medicinal liquid is in temperature required scope, wait for that this stage treatment finishes, and enters next stage.
6, the emptying recovery of medicinal liquid:
Keep buckle V2, buckle V3 to open, buckle V1, buckle V4 close, and start peristaltic pump, and medicinal liquid is from patient abdominal cavity via filter F, and medicinal liquid is finally collected in liquid-collection bag, finishes whole hyperthermia-chemotherapy therapeutic process after liquid medicine collecting.
Perfusion circulating pipeline device provided by the invention, by selecting the buckle of varying number and being arranged at the diverse location of circulation line, can be used for other abdominal cavity thermotherapys that treatment stage number is different from the present embodiment with requirement.
Perfusion circulating pipeline device provided by the invention, by the break-make of buckle, adjusts circulating pipeline device and is adapted to different treatment stages, meets the requirement of abdominal cavity thermotherapy; Use hot plate heating, system is simple and reliable, to medicinal liquid without destruction; Adopt temperature-measuring tee joint, be convenient to arrange temperature detecting point, can guarantee accurate detected temperatures and control temperature, thereby guarantee the therapeutic effect of abdominal cavity thermotherapy; Adopt liquid-collection bag, be convenient to medicinal liquid and inject, can entrained air in easy to operate and cyclic process herb liquid, guarantee therapeutic effect; After completed treatment, be all recycled to medicinal liquid liquid-collection bag, without revealing, environmentally safe; Pump line is configured in heating bag both sides, avoids heating bag flatulence; Filter is set, can effectively filters out the micro-bolt of tissue, prevent from occurring in cyclic process the phenomenon of blocking pipeline, circulation is reliable.
More than describe preferred embodiment of the present invention in detail.Should be appreciated that those of ordinary skill in the art just can design according to the present invention make many modifications and variations without creative work.Therefore, all technical staff in the art, all should be in by the determined protection domain of claims under this invention's idea on the basis of existing technology by the available technical scheme of logical analysis, reasoning, or a limited experiment.
Claims (10)
1. a perfusion circulating pipeline device, for abdominal cavity thermotherapy, it is characterized in that, described circulating pipeline device comprises circulation pipe, be arranged at pump line, liquid-collection bag on peristaltic pump, be arranged at heating bag, threeway, temperature-measuring tee joint, filter and buckle on hot plate, and described circulation pipe is connected with described pump line, described liquid-collection bag, described heating bag, described threeway, described temperature-measuring tee joint, described filter by female Luer; Described pump line is used to described medicinal liquid circulation that power is provided, described heating bag is used to described medicine liquid heating, described temperature-measuring tee joint is for detection of the temperature of described medicinal liquid, and described filter is used for filtering described medicinal liquid, and described buckle is used for adjusting described circulating pipeline device and is adapted to multiple treatment stages.
2. perfusion circulating pipeline device as claimed in claim 1, it is characterized in that, described temperature-measuring tee joint comprises first, second and the 3rd temperature-measuring tee joint, described the first temperature-measuring tee joint is for detection of the temperature of the medicinal liquid in inflow abdominal cavity, described the second temperature-measuring tee joint is for detection of the temperature of the medicinal liquid in outflow abdominal cavity, and described the 3rd temperature-measuring tee joint is for detection of the temperature of the medicinal liquid of the heating bag of flowing through.
3. perfusion circulating pipeline device as claimed in claim 2, it is characterized in that, described threeway comprises the first threeway and the second threeway, described pump line comprises the first pump line and the second pump line, the described the 1 is common to the outlet and the described filter that are communicated with the first pump line, described liquid-collection bag, and the described the 23 is common to the entrance and described the first temperature-measuring tee joint that are communicated with the second pump line, described liquid-collection bag.
4. perfusion circulating pipeline device as claimed in claim 3, is characterized in that, described the first pump line and described the second pump line are arranged at the two ends of described heating bag.
5. perfusion circulating pipeline device as claimed in claim 3, is characterized in that, described buckle is four.
6. perfusion circulating pipeline device as claimed in claim 5, it is characterized in that, described buckle comprises the first buckle being arranged between described liquid-collection bag and described the first threeway, be arranged at the second buckle between described the first threeway and described filter, be arranged at the 3rd buckle between described liquid-collection bag and described the second threeway, and be arranged at the 4th buckle between described the second threeway and described the first temperature-measuring tee joint.
7. perfusion circulating pipeline device as claimed in claim 6, it is characterized in that, described treatment stage comprises self-loopa heating period, injection stage, holding stage and emptying recovery stage, when keeping described first, the 3rd buckle, open, described second, the 4th buckle is closed, and adjusts described circulating pipeline device and is adapted to the described self-loopa heating period; When keeping described first, the 4th buckle to open, described second, third buckle is closed, and adjusts described circulating pipeline device and is adapted to the described injection stage; When keeping described second, the 4th buckle to open, described first, the 3rd buckle is closed, and adjusts described circulating pipeline device and is adapted to described holding stage; When keeping described second, third buckle to open, described first, the 4th buckle is closed, and adjusts described circulating pipeline device and is adapted to described emptying recovery stage.
8. perfusion circulating pipeline device as claimed in claim 1, is characterized in that, is provided with three-back-shaped pipeline of arranging in described heating bag.
9. perfusion circulating pipeline device as claimed in claim 1, is characterized in that, described liquid-collection bag arranges liquid medicine injection entrance.
10. perfusion circulating pipeline device as claimed in claim 1, is characterized in that, described circulation pipe adopts medical macromolecular materials to make.
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| CN201410008370.XA CN103751880B (en) | 2014-01-08 | 2014-01-08 | Circulation pipeline device for intraperitoneal chemohyperthermia |
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| CN201410008370.XA CN103751880B (en) | 2014-01-08 | 2014-01-08 | Circulation pipeline device for intraperitoneal chemohyperthermia |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105727426A (en) * | 2016-01-22 | 2016-07-06 | 深圳迈地海特科技有限公司 | Body cavity hyperthemal perfusion circulating device |
| CN110393627A (en) * | 2019-08-29 | 2019-11-01 | 吉林省迈达医疗器械股份有限公司 | A kind of perfusion unit in use for thermochemical therapeutics for abdominal cavity |
| CN112914818A (en) * | 2021-04-02 | 2021-06-08 | 河南中栋医疗科技有限公司 | Electrical heating abdominal cavity thermal perfusion treatment system |
| CN115089287A (en) * | 2022-06-21 | 2022-09-23 | 河南中栋医疗科技有限公司 | High-precision hot-filling temperature control system |
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| CN1593359A (en) * | 2004-06-24 | 2005-03-16 | 上海交通大学 | Intelligentized radio frequency thermoradiotherapeutic instrument for bladder |
| CN101897636A (en) * | 2010-08-06 | 2010-12-01 | 上海交通大学 | Intraperitoneal hyperthermic perfusion chemotherapy instrument in operation |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105727426A (en) * | 2016-01-22 | 2016-07-06 | 深圳迈地海特科技有限公司 | Body cavity hyperthemal perfusion circulating device |
| CN110393627A (en) * | 2019-08-29 | 2019-11-01 | 吉林省迈达医疗器械股份有限公司 | A kind of perfusion unit in use for thermochemical therapeutics for abdominal cavity |
| CN112914818A (en) * | 2021-04-02 | 2021-06-08 | 河南中栋医疗科技有限公司 | Electrical heating abdominal cavity thermal perfusion treatment system |
| CN115089287A (en) * | 2022-06-21 | 2022-09-23 | 河南中栋医疗科技有限公司 | High-precision hot-filling temperature control system |
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Effective date of registration: 20210111 Address after: 510080 4th floor, building 1, No.1 Keyuan Road, Baiyun District, Guangzhou City, Guangdong Province Patentee after: GUANGZHOU BRIGHT MEDICAL TECHNOLOGY Co.,Ltd. Address before: 200240 No. 800, Dongchuan Road, Shanghai, Minhang District Patentee before: SHANGHAI JIAO TONG University |
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Inventor after: Sheng Xinjun Inventor after: Wang Teng Inventor after: Zhu Xiangyang Inventor after: Yang Qiumeng Inventor after: Huang Diwen Inventor after: Cui Shuzhong Inventor before: Sheng Xinjun Inventor before: Wang Teng Inventor before: Zhu Xiangyang Inventor before: Yang Qiumeng |