CN1224414C - Suppository for treating gynecopathy and its preparation technology - Google Patents
Suppository for treating gynecopathy and its preparation technology Download PDFInfo
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- CN1224414C CN1224414C CN 03143332 CN03143332A CN1224414C CN 1224414 C CN1224414 C CN 1224414C CN 03143332 CN03143332 CN 03143332 CN 03143332 A CN03143332 A CN 03143332A CN 1224414 C CN1224414 C CN 1224414C
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- suppository
- vagina
- water
- cotton strips
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Abstract
The present invention discloses a suppository for curing gynecological diseases. The raw materials of the suppository for curing gynecological diseases comprise lightyellow sophora roots, stemona roots, common cnidium fruit, agrimony, Taiwan beautyberry leaves, alum, boronic acids, borneol and camphor; glycerogelatin substrates are added to the raw materials; and the suppository is prepared. The present invention has the advantages of convenient use, safety, sanitation, good curative effect, no secondary pollution, no toxic and side effect, etc. The suppository for curing gynecological diseases sends the suppository made of sanitary cotton strips to the depth of vagina by a disposable nontoxic propeller; the cotton strips rapidly expand after encountering body fluid, and medicaments can not flow out; the exhaust of the cotton strips is convenient and free, and inflammatory secretion of the vagina can be brought outside a body together with the cotton strips; thus, the vagina can be cleaned, and clothing can not be polluted; and in addition, the present invention provides a preparation of pure traditional Chinese medicaments and has the characteristics of no toxic and side effect and safe use.
Description
Technical field:
The present invention relates to a kind of medical suppository and preparation technology thereof.
Technical background:
Mycotic, infusorian property, bacillary nonspecific vaginitis, cervicitis, cervical erosion are the modal diseases of women.Though it is a lot of to treat the external used medicine of above-mentioned disease at present, main dosage form has water preparation, ordinary suppository, tablet, capsule, powder, unguentum etc., and all there is problem and shortage in various degree in these dosage forms.At first be that to enter the degree of depth of vagina not enough, medicine can not directly act on focus; It two is that medicine enters part medicine outflow is arranged after vagina dissolves, and directly influence effectively gives concentration; It three is very easily pollution clothes of the rheuminess thing that outflows with medicine, causes new infection chance.
Summary of the invention:
The objective of the invention is to: provide a kind of and medicine directly can be sent into the vagina depths, make effective ingredient directly act on focus, and can make medicine not outflow, avoid superinfection, safe and reliable suppository is to overcome the deficiencies in the prior art.
The present invention is achieved in that its raw material consumption is: Radix Sophorae Flavescentis 200~1000g, the Radix Stemonae 100~500g, Fructus Cnidii 100~500g, Herba Agrimoniae 100~500g, Folium Callicarpae Formosanae 100~500g, Alumen 5~20g, boric acid 10~100g, Borneolum Syntheticum 5~20g, Camphora 5~20g, the glycerol adding gelatin substrate is made.
Its preparation technology is: get Radix Sophorae Flavescentis earlier, the Radix Stemonae, Fructus Cnidii, Herba Agrimoniae, five medicines of Folium Callicarpae Formosanae decoct with water three times through cleaning processing, and first and second time adds 10 times in water, decoct 2 hours, add 8 times in water for the third time, decocted collecting decoction 1 hour, filter, be concentrated in right amount, add 95% ethanol, regulate amount of alcohol 30~35%, leave standstill, make precipitation, get supernatant, filter, behind the filtrate recycling ethanol, it is standby to be concentrated into relative density and to be 1.3~1.35 extractum; Other gets glycerol, gelatin prepares glycerol gelatin matrix, adds boric acid, Alumen then successively, adds extractum again, camphorates at last, Borneolum Syntheticum, in the injected plastic pipe box, more cotton rod is placed in one while hot, inlays and makes suppository.
The present invention compared with prior art has easy to use, safe, health, good, the no superinfection of therapeutic effect, advantage such as have no side effect.The present invention is that the suppository that will make with tapon is sent into the vagina depths with disposable nontoxic propeller, because of adopting water-soluble base, the rapid expansion do not outflowed medicine after cotton sliver was met body fluid, cotton sliver is discharged conveniently freely, and the vaginitis sexual secretion together can be taken out of externally, not only can clean vagina but also pollution clothes not.In addition, the present invention is a pure Chinese medicinal preparation, has no side effect, and is safe in utilization.Through to 60 routine case clinical practices, obtained good curative effect, total effective rate reaches 100%.Details are as follows for relevant clinical treatment situation:
1, clinical data: case 60 examples, colpitis mycotica 10 examples wherein, nonspecific vaginitis 10 examples, trichomonal vaginitis 10 examples, 19~60 years old age, average 39 years old.
2, administrated method: behind the pudendum cleaning, directly suppository is pushed intravaginal, once a day, each one, take out after 4 hours, 6 days is a course of treatment, during stop with other anti-inflammation class medicines.
3, curative effect judgment criteria:
(1) cure: transference cure, cervical erosion inspection disappear or below I °, inspections such as (1) mycete, gonococcus, infusorian turn out cloudy twice negative;
(2) effective: inflammatory symptom and sign take an evident turn for the better, but all do not disappear, and inspections such as mycete, gonococcus, infusorian are turned out cloudy for the first time, and be for the second time suspicious;
(3) inflammatory symptom and sign do not have change, and mycete, gonococcus, infusorian are still positive.
Through observing, colpitis mycotica 10 examples are cured 10 examples, nonspecific vaginitis 10 examples are cured 10 examples, trichomonal vaginitis 10 examples, cure 10 examples, gonococcal vaginitis 10 examples are cured 8 examples, effective 2 examples, senile vaginitis 10 examples are cured 9 examples, effective 1 example, cervical erosion II °-III ° 10 examples are cured 9 examples, effective 1 example.Cure rate 95%, total effective rate 100%.
By clinical trial certificate, the present invention is a kind of existing efficient antiinflammatory action, and the brand-new type gynecological external use medicament of good purification vagina effect is arranged again.Its great advantage is: (1) contains efficient sterilizing, insect killing substance, has very strong anti-inflammation and sterilization effect, and only 6 days (6 times) can obtain satisfactory effect; (2) easy to use; (3) totally nontoxic is non-stimulated; (4) be easy to preserve; (5) sanitation and hygiene after the medication, not pollution clothes.
The specific embodiment:
Embodiments of the invention: to produce 1000 suppositorys is example, gets Radix Sophorae Flavescentis 642.9g earlier, Radix Stemonae 321.4g, Fructus Cnidii 321.4g, Herba Agrimoniae 321.4g, Folium Callicarpae Formosanae 321.4g decoct with water three times through cleaning processing, first and second time adds 10 times in water, decocted 2 hours, and added 8 times in water for the third time, decocted 1 hour, collecting decoction, filter, be concentrated in right amount, add 95% ethanol, regulate amount of alcohol 30~35%, leave standstill, make precipitation, get supernatant, filter, behind the filtrate recycling ethanol, it is standby to be concentrated into relative density and to be 1.3~1.35 extractum; Other gets glycerol 260g, gelatin 950g prepares glycerol gelatin matrix, adds boric acid 60g, Alumen 10g then successively, adds extractum again, camphorate at last 10g, Borneolum Syntheticum 5g inject the vinyon pipe box while hot, the aseptic cotton rod are placed in one again, after freezing, inlay and make 1000 suppositorys.
Claims (2)
1, a kind of suppository for the treatment of gynaecopathia, it is characterized in that: make: Radix Sophorae Flavescentis 200~1000g by following raw material, the Radix Stemonae 100~500g, Fructus Cnidii 100~500g, Herba Agrimoniae 100~500g, Folium Callicarpae Formosanae 100~500g, Alumen 5~20g, boric acid 10~100g, Borneolum Syntheticum 5~20g, Camphora 5~20g, the glycerol adding gelatin substrate.
2, a kind of technology for preparing the described treatment gynaecopathia of claim 1 suppository is characterized in that: get Radix Sophorae Flavescentis, the Radix Stemonae earlier, Fructus Cnidii, Herba Agrimoniae, five medicines of Folium Callicarpae Formosanae decoct with water three times through cleaning processing, first and second time adds 10 times in water, decocted 2 hours, and added 8 times in water for the third time, decocted 1 hour, collecting decoction, filter, be concentrated in right amount, add 95% ethanol, regulate amount of alcohol 30~35%, leave standstill, make precipitation, get supernatant, filter, behind the filtrate recycling ethanol, it is standby to be concentrated into relative density and to be 1.3~1.35 extractum; Other gets glycerol, gelatin prepares glycerol gelatin matrix, adds boric acid, Alumen then successively, adds extractum again, camphorates at last, Borneolum Syntheticum, in the injected plastic pipe box, more cotton rod is placed in one while hot, inlays and makes suppository.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 03143332 CN1224414C (en) | 2002-11-15 | 2003-09-26 | Suppository for treating gynecopathy and its preparation technology |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN02134099.4 | 2002-11-15 | ||
CN 02134099 CN1413696A (en) | 2002-11-15 | 2002-11-15 | Suppository for treating gynecopathy and its preparation technology |
CN 03143332 CN1224414C (en) | 2002-11-15 | 2003-09-26 | Suppository for treating gynecopathy and its preparation technology |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1500522A CN1500522A (en) | 2004-06-02 |
CN1224414C true CN1224414C (en) | 2005-10-26 |
Family
ID=34276006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 03143332 Expired - Lifetime CN1224414C (en) | 2002-11-15 | 2003-09-26 | Suppository for treating gynecopathy and its preparation technology |
Country Status (1)
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CN (1) | CN1224414C (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105477489A (en) * | 2014-05-15 | 2016-04-13 | 刘善奎 | Preparation method of suppository for treating cervical hypertrophy |
CN105169163B (en) * | 2015-10-20 | 2019-02-22 | 贵州长生药业有限责任公司 | A kind of compound suppository and preparation method thereof |
CN105534879B (en) * | 2016-01-15 | 2021-06-18 | 贵州双升制药有限公司 | Suppository and preparation method thereof |
CN106975040B (en) * | 2016-01-15 | 2020-08-18 | 贵州双升制药有限公司 | Suppository and preparation method thereof |
CN107362310A (en) * | 2017-08-15 | 2017-11-21 | 贵州长生药业有限责任公司 | It is a kind of to be used to repair Baicao Fuyanqing preparation of vagina environment and preparation method thereof |
-
2003
- 2003-09-26 CN CN 03143332 patent/CN1224414C/en not_active Expired - Lifetime
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CN1500522A (en) | 2004-06-02 |
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Address after: 550201 Guizhou city of Guiyang province Zhazuo Xiuwen County Pharmaceutical Industrial Park Patentee after: GUIZHOU CHANGSHENG PHARMACEUTICAL Co.,Ltd. Address before: 2, building 1, building 312, 550002 South Baoshan Road, Guiyang, Guizhou Patentee before: Guizhou Changsheng Pharmaceutical Co.,Ltd. |
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CX01 | Expiry of patent term | ||
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Granted publication date: 20051026 |