CN1219400A

CN1219400A - Naoxinkang-hypotensor

Info

Publication number: CN1219400A
Application number: CN 97108549
Authority: CN
Inventors: 张锁成
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-12-11
Filing date: 1997-12-11
Publication date: 1999-06-16

Abstract

A Chinese medicine for lowering blood pressure and decreasing blood fat is prepared from 14 Chinese medicinal materials such as Flemingia prunella spike, notoginseng, dogbane, white chrysanthemum flower, red sage root, schisandra fruit, etc.

Description

Naoxinkang-hypotensor

The present invention is a kind of Chinese medicine preparation for the treatment of hypertension, hyperlipidemia, hemiplegia.

Hypertension is human a kind of commonly encountered diseases, frequently-occurring disease, can reach 10-20% at Europe, the United States' sickness rate, and population of China hypertension prevalence is 7.7%.North China, northeast and coastal region in east China prevalence are higher than south and western region inland region.Age of onset, hypertensive prevalence obviously increases after 40 years old.From China's situation, the hyperpietic has following characteristics: the brain worker is higher than physical labourer; The city is higher than the rural area; The north is higher than south; The person is higher than no family history of hypertension person the family history of hypertension; Obesity is higher than not overweight people; High salt diet is higher than low salt diet person; Be addicted to drink, the cigarette person be higher than be not addicted to drink, the cigarette person; The driver and be engaged in the attention concentrator, movable few duty dealer patient is many.

Patients with hypertension, often along with the prolongation of medical history, increase the weight of and cause internal organs such as the heart, brain, kidney to produce pathological changes, as morbidities such as hypertensive heart disease, mental and physical efforts break down, renal insufficiency, cerebral hemorrhages, and poor prognosis.Jeopardize patient's life when serious.It is a kind of important disease that has a strong impact on human health.

The diuretic (as hydrochlorothiazide) of the influential blood volume of medicine that western medical treatment hypertension is used more; Sympathetic nervous system blocker (as clonidine); Vasodilation (as Li Suoping); Feritin system inhibitor etc.These medicines have played important effect at the high blood of treatment aspect the pressure.Do not allow the problem of looking but exist some yet, mainly be: use diuretin easily to cause hypokalemia, hyperlipidemia and hyperglycemia and hyperuricemia; Use a1 receptor impedance agent such as phentolamine,, often be unfavorable for blood pressure lowering causing diseases such as tachycardia simultaneously with the painstaking effort output increases because of it blocks the a2 receptor simultaneously.Be that the B receptor blocking agent of representative often reduces myocardial contraction and causes bradycardia with the propranolol, disturb the metabolism of sugar and fat simultaneously, initiation hyperlipidemia and hyperglycemia.Therefore, the hypertensive side effect of use western medicine never can be negligent.

Find according to retrieval, the Chinese medicine of treatment hypertension is very many, wherein have: " a kind of medicine for the treatment of hyperbarism " (CN1075612A), it contains 19 kinds of Radix Salviae Miltiorrhizaes, Flos Chrysanthemi, the Radix Paeoniae Alba, the Radix Rehmanniae, Rhizoma Chuanxiong, Folium Mori, Folium Bambusae, Herba Menthae, Cornu Saigae Tataricae, Semen Sinapis Albae, Magnetitum, Borneolum Syntheticum, Moschus, Gypsum Fibrosum, Cornu rhinocerotis, Radix Angelicae Sinensis, Bombyx mori L., Semen Impatientis, Radix Aristolochiae meter, several animal materials are wherein arranged, on the high side, and this prescription is complicated.

The present invention is intended to the reasonable compatibility by Chinese herbal medicine, reach blood fat reducing collateral dredging, Yin Yang balancing, blood circulation promoting and blood stasis dispelling, circulation of qi promoting hemostasis, Shugan Zhitong, promotion circulation, the preventing or arresting vomiting that reduces phlegm is means, blood fat reducing, stabilizing blood pressure, the promotion heart, cerebral blood circulation reach the purpose of treatment.

The hypertension doctor trained in Western medicine is thought: the height of blood pressure depends primarily on cardiac output, blood volume and peripheral vascular resistance three factors, and the factor of decision is the increase of Peripheral resistance.Therefore, Peripheral resistance is the key of hypertension mechanism.

The mosaic theory of American scholar Page is thought: hypertension is not that single factors triggers, but the result who has multiple factor to participate in, influence each other.These factors comprise: inherited genetic factors; Environmental factors; The kidney factor; The neuroendocrine factor; Factors such as peripheral blood vessel structure and dysfunction.

The traditional Chinese medical science is thought: belong to the Liver and kidney imbalance of YIN and YANG, the kidney resistance is not enough, excessive rising of liver-YANG, liver-wind stirring up internally more.Heart master blood, the luxuriant blood of liver, The spleen governs the blood, deficiency of heart-blood, the high Sheng of liver-yang then, the blood vessels retardance causes qi stagnation blood stasis.Cerebral embolism and myocardial infarction take place, symptoms such as brain rate apoplexy.

According to the theory of the traditional Chinese medical science " the capable then blood of gas is capable, and the stagnation of QI is blood stasis then ", abide by the old maxim of " control wind and control blood earlier; the blood sector-style is from going out ", select for use 14 flavor Chinese herbal medicine by blood pressure lowering collateral dredging, Yin Yang balancing, control the blood silt, circulation of qi promoting hemostasis, Shugan Zhitong, promote functions such as circulation, reach and bring high blood pressure down minimizing blood fat, dredging the meridian, disease controlling progressively reaches normal level.The present invention prescription has following Chinese herbal medicine: a thousand pieces of gold is dialled, Spica Prunellae, Herba Senecionis Chrysanthemoidis, Herba Apocyni veneti, winter folium mori, Flos Chrysanthemi, Radix Salviae Miltiorrhizae, Fructus Schisandrae Chinensis, Oletum Trogopterori, Radix Angelicae Sinensis, Radix Bupleuri, Rhizoma Chuanxiong, Herba Epimedii, Radix Aristolochiae.Wherein (weight percent content) a thousand pieces of gold is dialled (clematifinetiaual), accounts for 4.4-10%; Spica Prunellae (Prunella asiatiea N) accounts for 4.4-8.8%; Herba Senecionis Chrysanthemoidis (Grnura sagptum M) accounts for 6.6-8.8%; Herba Apocyni veneti (Apocynum laneifolium R) accounts for 8.8-10.8%; Winter folium mori (Morus alba L) accounts for 4.4-8.8%; Flos Chrysanthemi (Chrysanthemum indicum L) accounts for 6.6-8.0%; Fructus Schisandrae Chinensis (Schizandra chinensisB) accounts for 4.9-8.8%; Radix Salviae Miltiorrhizae (SalviaMiltiorrhiza B) accounts for 8.8-11.4%; Oletum Trogopterori (Trogopterusxanthipes M) accounts for 3.2-6.6%; Radix Angelicae Sinensis (Anglica sinensis D) accounts for 6.4-6.8%; Radix Bupleuri (Bupleurum chinense D) accounts for 4.0-6.6%; Rhizoma Chuanxiong (Liguseicum wallichii F) accounts for 6.0-9.4%; Herba Epimedii (Epimediumbyevcornu M) accounts for 2.4-10.0%; Radix Aristolochiae (Aristolochia debilis S) accounts for 3.4-8.2%.Preferential composition proportioning of recommending is: a thousand pieces of gold is dialled 8.8 Spica Prunellaes, 8.8 Herba Senecionis Chrysanthemoidiss, 8.8 Herba Apocyni venetis, 4.4 winter folium moris, 8.8 Flos Chrysanthemis, 6.8 Radix Salviae Miltiorrhizaes, 10.0 Fructus Schisandrae Chinensis, 8.8 Oletum Trogopteroris, 6.6 Radix Angelicae Sinensis, 6.6 Radix Bupleuri, 6.6 Rhizoma Chuanxiongs, 6.6 Herba Epimedii, 4.4 Radix Aristolochiaes 4.0.The manufacture method of Naoxinkang-hypotensor is: with said herbal medicine, usefulness vacuum pulverizer is pulverized respectively, behind the thin square-bottomed bamboo basket of 100 orders, gets final product in the glue of the 100mg that packs into excessively.The patient can be according to state of an illness weight, and day pays three times, each 5-10 grain.10 days is a course of treatment, and this medicine continued to take in one day, golden to the state of an illness.

Using the present invention to treat hypertension obviously has the following advantages:

1, this product is a pure Chinese medicinal preparation, has no side effect.

2, treatment is rapid, stable curative effect;

3, healing back relapse rate is low;

4, therapeutic domain is wide, and is effective, and through Preliminary Clinical Observation, this prescription can bring high blood pressure down rapidly, solves cerebral ischemia.Effective treatment and prophylaxis of hypertension, hyperlipidemia, cerebral ischemia.Simultaneously to the intercurrent disease of hypertension such as arteriosclerosis, brain vertebra plug, myocardial infarction, cerebral hemorrhage, hemiplegia, numb limbs and tense tendons, cerebral hernia aphasia, cerebral concussion, angina cordis.The treatment effective percentage is 95%, and effective percentage is more than 80%.

Seven, embodiment:

Example 1:

A thousand pieces of gold is dialled 8.8% Spica Prunellae, 8.8% Herba Senecionis Chrysanthemoidis, 8.8% Herba Apocyni veneti 9.4%

Winter folium mori 8.8% Flos Chrysanthemi 6.8% Radix Salviae Miltiorrhizae 10.4% Fructus Schisandrae Chinensis 8.8%

Oletum Trogopterori 6.6% Radix Angelicae Sinensis 6.4% Radix Bupleuri 4.6% Rhizoma Chuanxiong 6.0%

Herba Epimedii 2.4% Radix Aristolochiae 3.4%

Example 2:

A thousand pieces of gold is dialled 4.4% Spica Prunellae, 4.4% Herba Senecionis Chrysanthemoidis, 6.6% Herba Apocyni veneti 10.8%

Winter folium mori 6.6% Flos Chrysanthemi 6.6% Radix Salviae Miltiorrhizae 11.4% Fructus Schisandrae Chinensis 8.8%

Oletum Trogopterori 3.2% Radix Angelicae Sinensis 6.8% Radix Bupleuri 4.6% Rhizoma Chuanxiong 9.4%

Herba Epimedii 8.8% Radix Aristolochiae 8.2%

Example 3:

A thousand pieces of gold is dialled 10.0% Spica Prunellae, 6.4% Herba Senecionis Chrysanthemoidis, 8.8% Herba Apocyni veneti 8.8%

Winter folium mori 4.4% Flos Chrysanthemi 8.0% Radix Salviae Miltiorrhizae 8.8% Fructus Schisandrae Chinensis 4.9%

Oletum Trogopterori 4.4% Radix Angelicae Sinensis 6.6% Radix Bupleuri 6.6% Rhizoma Chuanxiong 6.7%

Herba Epimedii 10.0% Radix Aristolochiae 5.6%

Claims

1, a kind of Chinese medicine preparation for the treatment of hypertension, hyperlipidemia, hemiplegia---Naoxinkang-hypotensor is characterized in that consisting of (content is weight percentage, down together):

A thousand pieces of gold is dialled 4.4-10 Spica Prunellae 4.4-8.8 Herba Senecionis Chrysanthemoidis 6.6-8.8

Herba Apocyni veneti 8.8-10.8 winter folium mori 4.4-8.8 Flos Chrysanthemi 6.6-8.0

Radix Salviae Miltiorrhizae 8.8-11.4 Fructus Schisandrae Chinensis 4.9-8.8 Oletum Trogopterori 3.2-6.6

Radix Angelicae Sinensis 6.4-6.8 Radix Bupleuri 4.0-6.6 Rhizoma Chuanxiong 6.0-9.4

Herba Epimedii 2.4～10.0 Radix Aristolochiae 3.4-8.2

2, according to the described Naoxinkang-hypotensor of claim 1, it is characterized in that consisting of:

A thousand pieces of gold is dialled 8.8 Spica Prunellaes, 8.8 Herba Senecionis Chrysanthemoidiss, 8.8 Herba Apocyni venetis 4.4

Winter folium mori 8.8 Flos Chrysanthemis 6.8 Radix Salviae Miltiorrhizaes 1.0 Fructus Schisandrae Chinensis 8.8

Oletum Trogopterori 6.6 Radix Angelicae Sinensis 6.6 Radix Bupleuri 6.6 Rhizoma Chuanxiongs 6.6

Herba Epimedii 4.4 Radix Aristolochiaes 4.0