CN1148208C - Medicine for curing diabetes - Google Patents
Medicine for curing diabetes Download PDFInfo
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- CN1148208C CN1148208C CNB011041862A CN01104186A CN1148208C CN 1148208 C CN1148208 C CN 1148208C CN B011041862 A CNB011041862 A CN B011041862A CN 01104186 A CN01104186 A CN 01104186A CN 1148208 C CN1148208 C CN 1148208C
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Abstract
The present invention relates to a medicine for the treatment of diabetes, which is prepared from the following Chinese herbal medicines, such as astragalus root, red sage root, red peony root, kakuda figwort root, hemlock parsley, suberect spatholobus stem, scutellaria root, rhizoma coptidis, angelica, barbary wolfberry fruit, etc., and capsules are prepared. The present invention can treat the diabetes according to the principle of promoting blood circulation for removing blood stasis, supplementing qi and nourishing yin. According to the summary of clinical tests, the medicine can not only effectively lower blood sugar, but also improve various clinical symptoms, and the occurrence of complications is prevented and reduced.
Description
The present invention relates to a kind of medicine for the treatment of diabetes, particularly relate to a kind of treatment diabetes medicament of making by Chinese herbal medicine and its method for making.
Diabetes be in a kind of because body carbohydrate metabolism disturbance to cause blood sugar increasing be the general endocrine metabolism disease of main clinical characteristics.Along with the raising of people's living standard, the variation of dietary structure, the sickness rate of diabetes also rises year by year.The western medical treatment diabetes adopt sulphanylureas, biguanides and insulin medicament treatment mostly, though their hypoglycemic activities are obvious, but only can reach the degree of regulating metabolism disorder, and the Western medicine side effect is big, take for a long time, can damage liver, kidney, influence gastrointestinal function, and may cause taking place multiple diabetic complications.
TCM treatment of diabetes is with a long history.The category of the diabetes spp traditional Chinese medical science " diabetes ", traditional Chinese medical science successive dynasties treatment diabetes, all be occur according to diabetes disappearing, in disappear, the different symptoms side of sending of diabetes due to kidney-deficiency selects medicine, though respectively give priority in treatment, nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst then are the fundamentums that the treatment diabetes are followed always.Yet, present diabetics shows the fewer and feweri of typical " three-many-one-little " symptom, this wherein no doubt is because some patient is a non-insulin-depending type, fall ill and know for many years and not, early stage three types of diabetes symptom disappears, and only just made a definite diagnosis later on and suffered from diabetes complication occurring, be through after the Drug therapy but quite a few is also arranged, though control ratio is more satisfactory aspect blood glucose and glucose in urine, the patient that subjective symptom is eliminated not yet.Clinical practice proves that diabetes develop into to a certain degree, and when especially being associated with chronic blood vessel, neuropathy, perhaps life-time service insulinize person is usually with the appearance of blood stasis phenomenon.For this type of patient, if, obviously do not meet clinical practice again according to the traditional nourishing YIN and clearing away heat method treatment of the traditional Chinese medical science.
The purpose of this invention is to provide a kind of medicine of using the method treatment diabetes of blood circulation promoting and blood stasis dispelling, supplementing QI and nourishing YIN, and the method for making of this medicine.
Medicine of the present invention is made up of Chinese medicines such as the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Scrophulariae, Radix Puerariae, Rhizoma Chuanxiong, Rhizoma Atractylodis, the Radix Rehmanniae, Caulis Spatholobi, Herba Leonuri, Radix Scutellariae, Rhizoma Coptidis, Radix Angelicae Sinensis, Fructus Lycii, the Radix Aucklandiae, and its parts by weight are:
5～10 parts of 5～10 parts of Radix Salviae Miltiorrhizaes of the Radix Astragali
5～10 parts of 2～5 portions of Radix Scrophulariae of Radix Paeoniae Rubra
2～5 parts of 2～5 parts of Rhizoma Chuanxiongs of Radix Puerariae
5～10 parts in 2～5 parts of Radix Rehmanniae of Rhizoma Atractylodis
5～10 parts of 5～10 parts of Herba Leonuris of Caulis Spatholobi
1～2 part of 2～5 portions of Rhizoma Coptidis of Radix Scutellariae
2～5 parts of 2～5 parts of Fructus Lycii of Radix Angelicae Sinensis
2～5 parts of the Radix Aucklandiae
The further drug weight of the present invention consists of:
6 parts of 6 parts of Radix Salviae Miltiorrhizaes of the Radix Astragali
6 parts of 3 portions of Radix Scrophulariae of Radix Paeoniae Rubra
2 parts of 3 parts of Rhizoma Chuanxiongs of Radix Puerariae
6 parts in 3 parts of Radix Rehmanniae of Rhizoma Atractylodis
6 parts of 6 parts of Herba Leonuris of Caulis Spatholobi
1.2 parts of 2 portions of Rhizoma Coptidis of Radix Scutellariae
2 parts of 2 parts of Fructus Lycii of Radix Angelicae Sinensis
2 parts of the Radix Aucklandiae
The concrete method for making of medicine of the present invention is:
A) Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Radix Scutellariae, Rhizoma Coptidis, Radix Aucklandiae pulverize separately are become 80～100 purpose fine powders, make the crude drug powder after mixing by weight;
B) Radix Astragali, Radix Paeoniae Rubra, Radix Scrophulariae, Radix Puerariae, Rhizoma Chuanxiong, the Radix Rehmanniae, Caulis Spatholobi, Herba Leonuri, Radix Angelicae Sinensis, Fructus Lycii are mixed by weight after, decoct with water 2 times, each decoction water consumption is 2～4 times of dose, decocts 2.5～3 hours for the first time, decocts 2～2.5 hours for the second time;
C) collecting decoction, the simmer down to relative density is 1.20～1.24 thick paste after filtering, characteristics are and should not decoct;
D) the crude drug powder is joined in the thick paste, mix homogeneously in 60 ℃ of dryings, is ground into powder, and crosses 100～120 mesh sieves;
E) sieve the back powder incapsulates.
Diabetes develop into to a certain degree, when especially being associated with chronic blood vessel, neuropathy, perhaps life-time service insulinize person usually with the performance of blood stasis disease, has ecchymosis such as face, facial dark and gloomy, limbs pain, numbness, sore spot are fixed and are not moved precordialgia, hemiplegia, there are ecchymosis or petechia in dimly pale tongue, tongue limit, and sublingual vessel is livid purple, anger is opened or the like.
Modern medicine study finds through pathological anatomy, and part of diabetes mellitus patient's pancreas blood vessel exists inaccessible obstructed phenomenon, has 70% diabetics to die from the heart, cerebrovascular complication approximately.Because formation, the blood vessel elasticity of atherosclerotic plaque weaken, the platelet aggregation enhancing, cause vessel wall thickening, inner wall coarse, inner chamber narrow, add the hemorheology sexual abnormality, blood viscosity increases, cause thrombosis or blood capillary thromboembolism, capillary basement membrane thickens or blocks, blood stasis, slow blood flow and microcirculation disturbance, this illustrates that all diabetes blood stasis disease has its pathophysiology basis.
Theory of Chinese medical science is thought: diabetes blood stasis disease is caused by deficiency of both QI and YIN.Qi as the commander of blood, blood being the mother of qi, and the deficiency of vital energy promotes unable, and blood operation is not smooth, and is slowly not smooth, forms blood stasis, i.e. so-called " deficiency of vital energy is turbid to be stayed "; Hyperactivity of fire caused by deficiency of YIN decocts body fluid, and homogeny of clear fluid and blood, body fluid deficiency liquid hyperlipidemia at least are not smooth, also can become the stasis of blood, i.e. so-called " deficiency of YIN stasis ".Can block mechanism of qi again after blood stasis forms, body fluid is lost in compress, increase the weight of the diabetes state of an illness and multiple late morbidity or complication occur.
In prescription of the present invention, select the Radix Astragali, Rhizoma Atractylodis, Radix Scrophulariae, Radix Rehmanniae supplementing QI and nourishing YIN for use, nourishing the liver and kidney passes unimpeded in order to do the cloudy prosperous then blood of gas to effect a permanent cure; With Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Herba Leonuri blood circulation promoting and blood stasis dispelling, Radix Angelicae Sinensis, Radix Paeoniae Rubra blood nourishing acupuncture-stimulating, the removing blood stasis tissue regeneration promoting is to take stopgap measures; Radix Aucklandiae promoting the circulation of QI to relieve pain, make the smooth blood of gas capable, strengthen the blood stasis dispelling effect of blood circulation promoting medicine; The Radix Puerariae promoting the production of body fluid to quench thirst, blood vessel dilating; Radix Scutellariae is joined the Rhizoma Coptidis clearing away heat-fire; Caulis Spatholobi is enriched blood and invigorates blood circulation, and channels sootheing and network vessel quickening is controlled numb limbs and tense tendons; The cloudy blood of Fructus Lycii nourishing the liver and kidney; Each medicine all has the effect of blood sugar lowering in addition, and all medicine compatibilities are played reinforcing both QI and YIN, the effect of the blood sugar lowering of invigorating blood circulation altogether.
Use Drug therapy deficiency of both QI and YIN blood stasis type diabetes of the present invention, not only can eliminate or improve patient's clinical symptoms, blood sugar lowering, glucose in urine, and can correct the unusual hemorheological property index of patient, the generation of prevention and minimizing diabetes chronic complication.For the insulin-dependent patient of long term injections insulinize or the non-insulin-depending type patient of chronic complication is arranged, use Drug therapy of the present invention after, part patient's insulin dosage is reduced even stop using, and the state of an illness still can be controlled satisfaction.
Lot of experiments confirms, activating blood and removing stasis drug can blood vessel dilating, blood flow is accelerated and the blood flow increase, and can suppress proliferation of fibrous tissue, correct and improve unusual hemorheological property, adjust blood coagulation and anticoagulation function, the elimination microcirculation disturbance, thereby improve sugar, the lipid metabolism of diabetics, the appearance that prevents or alleviate multiple blood vessel complication.
Western medicine thinks that the pathogeny of diabetes is also relevant with autoimmune.Because some autoimmune response can cause inflammation such as islets of langerhans lymphocytic infiltration, causes beta cell excreting insulin deficiency, measures insulin antibody in part of diabetes mellitus patient's blood.Pharmaceutical research proves that medicines such as the Herba Leonuri in the medicine of the present invention, Rhizoma Chuanxiong, Radix Angelicae Sinensis all have the effect that suppresses or eliminate the immunity blood group antibody, and therefore, medicine of the present invention can suppress immunoreation again in the activating blood and resolving stasis and treating diabetes, kills two birds with one stone.
By clinical observation to 159 routine deficiency of both QI and YIN blood stasis type diabeticss, prove medicine of the present invention at blood sugar lowering, correct patient unusual hemorheological property index, elimination and improve aspect effect such as clinical symptoms remarkable, clinical treatment diabetes total effective rate reaches 88.35%.
It below is concrete Application Example of the present invention.
Get 3kg Radix Salviae Miltiorrhizae, 1.5kg Rhizoma Atractylodis, 1kg Radix Scutellariae, 0.6kg Rhizoma Coptidis and the 1kg Radix Aucklandiae and be ground into 80～100 purpose fine powders with pulverizer respectively, make the crude drug powder after the mixing; In the extraction pot of packing into after the 3kg Radix Astragali, 1.5kg Radix Paeoniae Rubra, 3kg Radix Scrophulariae, 1.5kg Radix Puerariae, 1kg Rhizoma Chuanxiong, the 3kg Radix Rehmanniae, 3kg Caulis Spatholobi, 3kg Herba Leonuri, 1kg Radix Angelicae Sinensis, the mixing of 1kg Fructus Lycii, add 80kg water, decocted 3 hours, incline decocting liquid after, add water 50kg in the medicinal residues again, decocted 2 hours, and merged decocting liquid twice, filter the back is concentrated into relative density 1.20～1.24 (60 ℃) in concentration kettle thick paste; The crude drug powder is joined mix homogeneously in the thick paste, dry under 60 ℃ of conditions, and be ground into 100～120 purpose powder, the back of sieving uses capsule filler to be encased in 1
#In the capsule, after make finished product after the polishing of capsule polishing machine.
Claims (6)
1, a kind of medicine for the treatment of diabetes is characterized in that this medicine made by the Chinese herbal medicine of following portions by weight:
5～10 parts of 5～10 parts of Radix Salviae Miltiorrhizaes of the Radix Astragali
5～10 parts of 2～5 portions of Radix Scrophulariae of Radix Paeoniae Rubra
2～5 parts of 2～5 parts of Rhizoma Chuanxiongs of Radix Puerariae
5～10 parts in 2～5 parts of Radix Rehmanniae of Rhizoma Atractylodis
5～10 parts of 5～10 parts of Herba Leonuris of Caulis Spatholobi
1～2 part of 2～5 portions of Rhizoma Coptidis of Radix Scutellariae
2～5 parts of 2～5 parts of Fructus Lycii of Radix Angelicae Sinensis
2～5 parts of the Radix Aucklandiae.
2, treatment diabetes medicament according to claim 1 is characterized in that this medicine made by the Chinese herbal medicine of following portions by weight:
6 parts of 6 parts of Radix Salviae Miltiorrhizaes of the Radix Astragali
6 parts of 3 portions of Radix Scrophulariae of Radix Paeoniae Rubra
2 parts of 3 parts of Rhizoma Chuanxiongs of Radix Puerariae
6 parts in 3 parts of Radix Rehmanniae of Rhizoma Atractylodis
6 parts of 6 parts of Herba Leonuris of Caulis Spatholobi
1.2 parts of 2 portions of Rhizoma Coptidis of Radix Scutellariae
2 parts of 2 parts of Fructus Lycii of Radix Angelicae Sinensis
2 parts of the Radix Aucklandiae.
3, the method for making of the described treatment diabetes medicament of claim 1 is characterized in that:
A) Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Radix Scutellariae, Rhizoma Coptidis, Radix Aucklandiae pulverize separately are become 80～100 purpose fine powders, make the crude drug powder after mixing by weight;
B) Radix Astragali, Radix Paeoniae Rubra, Radix Scrophulariae, Radix Puerariae, Rhizoma Chuanxiong, the Radix Rehmanniae, Caulis Spatholobi, Herba Leonuri, Radix Angelicae Sinensis, Fructus Lycii are mixed by weight after, decoct with water 2 times, collecting decoction filters back simmer down to thick paste;
C) the crude drug powder is joined in the thick paste, mix homogeneously in 60 ℃ of dryings, is ground into powder and sieves;
D) sieve the back powder incapsulates.
4, the method for making of treatment diabetes medicament according to claim 3 is characterized in that described decocting with water, and each water consumption is 2～4 times of dose, decocts 2.5～3 hours for the first time, decocts 2～2.5 hours for the second time.
5, the method for making of treatment diabetes medicament according to claim 3 is characterized in that with decocting liquid simmer down to relative density being 1.20～1.24 thick paste.
6, the method for making of treatment diabetes medicament according to claim 3 is characterized in that pulverizing the back powder and crosses 100～120 mesh sieves.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011041862A CN1148208C (en) | 2001-02-26 | 2001-02-26 | Medicine for curing diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011041862A CN1148208C (en) | 2001-02-26 | 2001-02-26 | Medicine for curing diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1311017A CN1311017A (en) | 2001-09-05 |
| CN1148208C true CN1148208C (en) | 2004-05-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011041862A Expired - Fee Related CN1148208C (en) | 2001-02-26 | 2001-02-26 | Medicine for curing diabetes |
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| CN (1) | CN1148208C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100411653C (en) * | 2004-11-19 | 2008-08-20 | 周亚伟 | Chinese medicine composition for treating diabetes mellitus |
| CN102614405B (en) * | 2012-04-06 | 2015-03-11 | 刘英晓 | Traditional Chinese medicine decoction for curing limb pain caused by diabetic neuropathy |
| CN103083461A (en) * | 2012-12-06 | 2013-05-08 | 宁夏易欣回药科技有限公司 | Medicine composition for treating diabetes |
| CN115814026A (en) * | 2022-11-17 | 2023-03-21 | 浙江科呈科技服务有限公司 | Blood sugar reducing tablet and preparation process thereof |
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2001
- 2001-02-26 CN CNB011041862A patent/CN1148208C/en not_active Expired - Fee Related
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| CN1311017A (en) | 2001-09-05 |
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