CN104645140A - Traditional Chinese medicine composition for treating nephritic syndrome and preparation method of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating nephritic syndrome and preparation method of traditional Chinese medicine composition Download PDF

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CN104645140A
CN104645140A CN201510116050.0A CN201510116050A CN104645140A CN 104645140 A CN104645140 A CN 104645140A CN 201510116050 A CN201510116050 A CN 201510116050A CN 104645140 A CN104645140 A CN 104645140A
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radix
chinese medicine
medicine composition
traditional chinese
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朱克兰
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Abstract

The invention relates to a traditional Chinese medicine composition for treating nephritic syndrome and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following crude drugs in parts by weight: 13-17 parts of astragalus, 13-17 parts of semen plantaginis, 13-17 parts of semen coicis, 8-12 parts of radix codonopsis, 8-12 parts of tuckahoe, 8-12 parts of rhizoma alismatis, 8-12 parts of pyrrosia lingua, 8-12 parts of hawthorns, 8-12 parts of salvia miltiorrhiza, 8-12 parts of rhizoma atractylodis, 8-12 parts of mangnolia officinalis, 6-8 parts of rhizoma atractylodis macrocephalae, 6-8 parts of cassia twigs, 6-8 parts of grifola, 6-8 parts of angelica sinensis, 6-8 parts of fritillary bulbs, 6-8 parts of fructus aurantii, 3-5 parts of radix saposhnikoviae, 3-5 parts of radix sophorae flavescentis, 3-5 parts of orange peel and 3-5 parts of liquorice. The traditional Chinese medicine composition has the advantages of remarkable curative effect, no toxic or side effects, relatively low expense and the like.

Description

A kind of Chinese medicine composition for the treatment of nephrotic syndrome and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition for the treatment of nephrotic syndrome and preparation method thereof.
Background technology
Nephrotic syndrome can be caused by Different types of etiopathogenises, increases with glomerular basement membrane permeability, shows as one group of clinical syndrome of High-grade Proteinuria, hypoproteinemia, treating serious edema caused, hyperlipemia.The cause of disease comprises chronic glomerulonephritis, lipoids nephropathy, systemic lupus erythematosus (sle) nephropathy, amyloidosis, multiple myeloma, diabetes glomerulosclerosis, anaphylactoid purpura etc.Children's is based on lipoids nephropathy, be grown up with nephrotic chronic nephritis as common cause, there is common pathologic basis to be that glomerular basement membrane filter opening increases, discharge with urethra after blood plasma small molecular protein filters in a large number, cause plasma protein to reduce and protein metabolism disorder.
At present, the medicine being used for the treatment of nephrotic syndrome is more, although can play a role, it exists, and therapeutic effect is poor, side effect greatly, the deficiency such as costly.
Summary of the invention
The technical problem to be solved in the present invention is: be solve the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition for the treatment of nephrotic syndrome and preparation method thereof, the present invention have evident in efficacy, have no side effect, the advantage such as expense is lower.
Treat a Chinese medicine composition for nephrotic syndrome, be made up of the crude drug of following weight portion: Radix Astragali 13-17 part, Semen Plantaginis 13-17 part, Semen Coicis 13-17 part, Radix Codonopsis 8-12 part, Poria 8-12 part, Rhizoma Alismatis 8-12 part, Folium Pyrrosiae 8-12 part, Fructus Crataegi 8-12 part, Radix Salviae Miltiorrhizae 8-12 part, Rhizoma Atractylodis 8-12 part, Cortex Magnoliae Officinalis 8-12 part, Rhizoma Atractylodis Macrocephalae 6-8 part, Ramulus Cinnamomi 6-8 part, Polyporus 6-8 part, Radix Angelicae Sinensis 6-8 part, Bulbus Fritillariae Uninbracteatae 6-8 part, Fructus Aurantii 6-8 part, Radix Saposhnikoviae 3-5 part, Radix Sophorae Flavescentis 3-5 part, Pericarpium Citri Reticulatae 3-5 part, Radix Glycyrrhizae 3-5 part.
The Chinese medicine composition of described treatment nephrotic syndrome, it is preferably: be made up of the crude drug of following weight portion: the Radix Astragali 15 parts, Semen Plantaginis 15 parts, Semen Coicis 15 parts, Radix Codonopsis 10 parts, 10 parts, Poria, Rhizoma Alismatis 10 parts, Folium Pyrrosiae 10 parts, Fructus Crataegi 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Atractylodis 10 parts, Cortex Magnoliae Officinalis 10 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, Ramulus Cinnamomi 7 parts, Polyporus 7 parts, Radix Angelicae Sinensis 7 parts, Bulbus Fritillariae Uninbracteatae 7 parts, Fructus Aurantii 7 parts, Radix Saposhnikoviae 4 parts, Radix Sophorae Flavescentis 4 parts, Pericarpium Citri Reticulatae 4 parts, 4 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition of described treatment nephrotic syndrome is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Usage and consumption: Chinese medicine composition of the present invention is based on decoction, and every day 1 pair, divide and take for 2 times, early, evening respectively takes 1 time, within 10 days, is 1 course for the treatment of, and general 2-6 a course for the treatment of can be effectively; Also concentrated pill or concentrated capsule can be made into.
The beneficial effect that the present invention is compared with prior art had is: the present invention is under Traditional Chinese medical theory and clinical experience instruct, choose each crude drug and proportioning thereof, there is the function of enriching yin and nourishing kidney, removing dampness detumescence, activating QI to promote diuresis, realize the object for the treatment of nephrotic syndrome; The present invention have evident in efficacy, have no side effect, the advantage such as expense is lower, through clinical verification, it is 96% that the present invention treats nephrotic syndrome effective percentage.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine composition for nephrotic syndrome, be made up of the crude drug of following weight portion: the Radix Astragali 15 parts, Semen Plantaginis 15 parts, Semen Coicis 15 parts, Radix Codonopsis 10 parts, 10 parts, Poria, Rhizoma Alismatis 10 parts, Folium Pyrrosiae 10 parts, Fructus Crataegi 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Atractylodis 10 parts, Cortex Magnoliae Officinalis 10 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, Ramulus Cinnamomi 7 parts, Polyporus 7 parts, Radix Angelicae Sinensis 7 parts, Bulbus Fritillariae Uninbracteatae 7 parts, Fructus Aurantii 7 parts, Radix Saposhnikoviae 4 parts, Radix Sophorae Flavescentis 4 parts, Pericarpium Citri Reticulatae 4 parts, 4 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition of described treatment nephrotic syndrome is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Embodiment 2:
Treat a Chinese medicine composition for nephrotic syndrome, be made up of the crude drug of following weight portion: the Radix Astragali 13 parts, Semen Plantaginis 13 parts, Semen Coicis 13 parts, Radix Codonopsis 8 parts, 8 parts, Poria, Rhizoma Alismatis 8 parts, Folium Pyrrosiae 8 parts, Fructus Crataegi 8 parts, Radix Salviae Miltiorrhizae 8 parts, Rhizoma Atractylodis 8 parts, Cortex Magnoliae Officinalis 8 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Ramulus Cinnamomi 6 parts, Polyporus 6 parts, Radix Angelicae Sinensis 6 parts, Bulbus Fritillariae Uninbracteatae 6 parts, Fructus Aurantii 6 parts, Radix Saposhnikoviae 3 parts, Radix Sophorae Flavescentis 3 parts, Pericarpium Citri Reticulatae 3 parts, 3 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition of described treatment nephrotic syndrome is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Embodiment 3:
Treat a Chinese medicine composition for nephrotic syndrome, be made up of the crude drug of following weight portion: the Radix Astragali 17 parts, Semen Plantaginis 17 parts, Semen Coicis 17 parts, Radix Codonopsis 12 parts, 12 parts, Poria, Rhizoma Alismatis 12 parts, Folium Pyrrosiae 12 parts, Fructus Crataegi 12 parts, Radix Salviae Miltiorrhizae 12 parts, Rhizoma Atractylodis 12 parts, Cortex Magnoliae Officinalis 12 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Ramulus Cinnamomi 8 parts, Polyporus 8 parts, Radix Angelicae Sinensis 8 parts, Bulbus Fritillariae Uninbracteatae 8 parts, Fructus Aurantii 8 parts, Radix Saposhnikoviae 5 parts, Radix Sophorae Flavescentis 5 parts, Pericarpium Citri Reticulatae 5 parts, 5 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition of described treatment nephrotic syndrome is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Experimental example:
(1) clinical data: the present invention treat altogether Patients With Nephrotic Symdrome 50 example, wherein man 29 example, female 21 example, the age be 7-68 year.
(2) Therapeutic Method: Chinese medicine composition of the present invention is based on decoction, and every day 1 pair, divide and take for 2 times, early, evening respectively takes 1 time, 10 days is 1 course for the treatment of; Also concentrated pill or concentrated capsule can be made into.
(3) the standard of curative effect evaluation:
Cure: symptom all disappears; Main Physico-chemical tests index is normally;
Effective: symptomatology is eliminated or cardinal symptom is eliminated; Physico-chemical tests index is normal;
Effective: cardinal symptom disappears substantially; Main Physico-chemical tests index makes moderate progress;
Invalid: main Physico-chemical tests index is front unchanged with treatment.
(4) therapeutic outcome: the present invention treats Patients With Nephrotic Symdrome 50 example altogether, through the treatment of 2-6 the course for the treatment of, cures 34 examples, accounts for 68%, and effective 8 examples, account for 16%, and effective 6 examples, account for 12%, and invalid 2 examples, account for 4%, effective percentage is 96%.
(5) model case:
1, congratulate certain, female, 46 years old, edema of pair of lower extremities, malaise, hepatic and renal function, blood fat, blood glucose are normal, are nephrotic syndrome through hospital diagnosis; After taking 2 courses for the treatment of of Chinese medicine composition of the present invention, remission, after continuing to take 2 courses for the treatment of of Chinese medicine composition of the present invention, recovery from illness, does not recur so far.
2, Qu so-and-so, man, 51 years old, upper limb edema half a year, general weakness.Urinalysis finds: erythrocyte+, protein ++; After taking 2 courses for the treatment of of Chinese medicine composition of the present invention, remission, after taking again 2 courses for the treatment of of Chinese medicine composition of the present invention, recovery from illness, has no recurrence.
3, Shen, man, 63 years old, two lower limb and foot's edema 2 wheat harvesting period, urinalysis finds: erythrocyte ++, protein ++; Clinical diagnosis is for being nephrotic syndrome; After taking 2 courses for the treatment of of Chinese medicine composition of the present invention, remission, after taking again 3 courses for the treatment of of Chinese medicine composition of the present invention, recovery from illness, has no recurrence.

Claims (3)

1. treat a Chinese medicine composition for nephrotic syndrome, it is characterized in that: be made up of the crude drug of following weight portion: Radix Astragali 13-17 part, Semen Plantaginis 13-17 part, Semen Coicis 13-17 part, Radix Codonopsis 8-12 part, Poria 8-12 part, Rhizoma Alismatis 8-12 part, Folium Pyrrosiae 8-12 part, Fructus Crataegi 8-12 part, Radix Salviae Miltiorrhizae 8-12 part, Rhizoma Atractylodis 8-12 part, Cortex Magnoliae Officinalis 8-12 part, Rhizoma Atractylodis Macrocephalae 6-8 part, Ramulus Cinnamomi 6-8 part, Polyporus 6-8 part, Radix Angelicae Sinensis 6-8 part, Bulbus Fritillariae Uninbracteatae 6-8 part, Fructus Aurantii 6-8 part, Radix Saposhnikoviae 3-5 part, Radix Sophorae Flavescentis 3-5 part, Pericarpium Citri Reticulatae 3-5 part, Radix Glycyrrhizae 3-5 part.
2. the Chinese medicine composition for the treatment of nephrotic syndrome according to claim 1, is characterized in that: be made up of the crude drug of following weight portion: the Radix Astragali 15 parts, Semen Plantaginis 15 parts, Semen Coicis 15 parts, Radix Codonopsis 10 parts, 10 parts, Poria, Rhizoma Alismatis 10 parts, Folium Pyrrosiae 10 parts, Fructus Crataegi 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Atractylodis 10 parts, Cortex Magnoliae Officinalis 10 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, Ramulus Cinnamomi 7 parts, Polyporus 7 parts, Radix Angelicae Sinensis 7 parts, Bulbus Fritillariae Uninbracteatae 7 parts, Fructus Aurantii 7 parts, Radix Saposhnikoviae 4 parts, Radix Sophorae Flavescentis 4 parts, Pericarpium Citri Reticulatae 4 parts, 4 parts, Radix Glycyrrhizae.
3. the preparation method of the Chinese medicine composition for the treatment of nephrotic syndrome according to claim 1 and 2, is characterized in that: make decoction, concentrated pill or concentrated capsule according to a conventional method by Chinese medicine composition described in claim 1 or 2.
CN201510116050.0A 2015-03-17 2015-03-17 Traditional Chinese medicine composition for treating nephritic syndrome and preparation method of traditional Chinese medicine composition Pending CN104645140A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105727078A (en) * 2016-04-13 2016-07-06 张俊玲 Pharmaceutical composition for treating nephritic syndrome
CN106110014A (en) * 2016-07-21 2016-11-16 启东兴都水产品有限公司 The Chinese medicine composition that a kind for the treatment of is suffered from a deficiency of the kidney
CN113425826A (en) * 2021-07-09 2021-09-24 贾伟 Traditional Chinese medicine composition for treating minimal nephrosis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101069722A (en) * 2006-05-09 2007-11-14 广州康臣药业有限公司 Chinese medicine composition for treating kidney disease syndrome and preparing method
CN103393851A (en) * 2013-08-10 2013-11-20 常玲玲 Chinese medicinal preparation for treating nephrotic syndrome and preparation method
CN103919907A (en) * 2014-04-16 2014-07-16 浙江中医药大学 Medicament for treating nephrotic syndrome

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101069722A (en) * 2006-05-09 2007-11-14 广州康臣药业有限公司 Chinese medicine composition for treating kidney disease syndrome and preparing method
CN103393851A (en) * 2013-08-10 2013-11-20 常玲玲 Chinese medicinal preparation for treating nephrotic syndrome and preparation method
CN103919907A (en) * 2014-04-16 2014-07-16 浙江中医药大学 Medicament for treating nephrotic syndrome

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105727078A (en) * 2016-04-13 2016-07-06 张俊玲 Pharmaceutical composition for treating nephritic syndrome
CN106110014A (en) * 2016-07-21 2016-11-16 启东兴都水产品有限公司 The Chinese medicine composition that a kind for the treatment of is suffered from a deficiency of the kidney
CN113425826A (en) * 2021-07-09 2021-09-24 贾伟 Traditional Chinese medicine composition for treating minimal nephrosis

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Application publication date: 20150527