CN1203852C - 维得克西组合物 - Google Patents
维得克西组合物 Download PDFInfo
- Publication number
- CN1203852C CN1203852C CNB008059063A CN00805906A CN1203852C CN 1203852 C CN1203852 C CN 1203852C CN B008059063 A CNB008059063 A CN B008059063A CN 00805906 A CN00805906 A CN 00805906A CN 1203852 C CN1203852 C CN 1203852C
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- valdecoxib
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Diabetes (AREA)
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- Hematology (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
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- Molecular Biology (AREA)
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16985699P | 1999-12-08 | 1999-12-08 | |
| US60/169856 | 1999-12-09 | ||
| US18163500P | 2000-02-10 | 2000-02-10 | |
| US60/181635 | 2000-02-10 | ||
| US20226900P | 2000-05-05 | 2000-05-05 | |
| US60/202269 | 2000-05-05 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA200510065059XA Division CN1679556A (zh) | 1999-12-08 | 2000-12-04 | 维得克西组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
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| NZ514896A (en) | 1998-10-30 | 2003-11-28 | Rj Innovation | A method of preventing parturient hypocalcemia in animals and compositions used therein |
| KR100558239B1 (ko) | 1999-12-23 | 2006-03-10 | 화이자 프로덕츠 인크. | 증가된 약물 농도를 제공하는 제약학적 조성물 |
| CN1638739A (zh) * | 2000-08-18 | 2005-07-13 | 法玛西雅厄普约翰美国公司 | 治疗成瘾性障碍的化合物 |
| AU2002303577B2 (en) * | 2001-05-04 | 2006-06-08 | Merck & Co., Inc. | Method and compositions for treating migraines |
| BR0212778A (pt) * | 2001-09-26 | 2004-12-07 | Pharmacia Corp | Composições de desintegração intra-oral organolepticamente aceitáveis |
| SK1662004A3 (sk) * | 2001-10-10 | 2005-07-01 | Pharmacia Corporation | Intraorálne dezintegrujúce prípravky valdecoxidu pripravené rozprašovacím sušením |
| GB0124459D0 (en) * | 2001-10-11 | 2001-12-05 | Novartis Ag | Organic compounds |
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| US20030100595A1 (en) * | 2001-11-13 | 2003-05-29 | Aziz Karim | Oral dosage form of a sulfonamide prodrug |
| MXPA04006608A (es) * | 2002-01-07 | 2004-10-04 | Pharmacia Corp | Tratamiento de dolor, inflamacion y trastornos relacionados con inflamacion con una combinacion de inhibidor selectivo de ciclooxigenasa-2 y aspirina. |
| GB0201520D0 (en) * | 2002-01-23 | 2002-03-13 | Novartis Ag | Pharmaceutical uses |
| US7927613B2 (en) * | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| US7790905B2 (en) * | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
| WO2004000284A1 (en) * | 2002-06-21 | 2003-12-31 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions with improved dissolution |
| WO2003070237A1 (en) * | 2002-02-22 | 2003-08-28 | Warner-Lambert Company Llc | Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2 |
| CA2477923C (en) * | 2002-03-01 | 2021-02-23 | University Of South Florida | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
| GB0209265D0 (en) * | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| GB0209257D0 (en) * | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| AU2003247793A1 (en) * | 2002-06-26 | 2004-01-19 | Pharmacia Corporation | Stable liquid parenteral parecoxib formulation |
| EP1536788A1 (en) * | 2002-08-30 | 2005-06-08 | Pharmacia Corporation | Pharmaceutical solid dosage forms exhibiting reproductible drug release profile |
| US20060052432A1 (en) * | 2002-09-20 | 2006-03-09 | Julius Remenar | Pharmaceutical compositions with improved dissolution |
| JP4494712B2 (ja) * | 2002-11-12 | 2010-06-30 | 大日本住友製薬株式会社 | マルチプルユニット型徐放性製剤 |
| ES2640404T3 (es) | 2002-11-22 | 2017-11-02 | Grünenthal GmbH | Combinación de analgésicos seleccionados con inhibidores de la COX II |
| US8183290B2 (en) * | 2002-12-30 | 2012-05-22 | Mcneil-Ppc, Inc. | Pharmaceutically acceptable propylene glycol solvate of naproxen |
| WO2005000294A1 (en) * | 2003-06-06 | 2005-01-06 | Pharmacia Corporation | Selective inhibitor and an anticonvulsant agent for the treatment of central nervous system disorders |
| US20050004224A1 (en) * | 2003-06-10 | 2005-01-06 | Pharmacia Corporation | Treatment of Alzheimer's disease with the R(-) isomer of a 2-arylpropionic acid non-steroidal anti-inflammatory drug alone or in combination with a cyclooxygenase-2 selective inhibitor |
| WO2005007156A1 (en) * | 2003-07-10 | 2005-01-27 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and an angiotensin ii receptor antagonist for the treatment of central nervous system damage |
| CA2542277A1 (en) * | 2003-10-21 | 2005-05-12 | Pharmacia Corporation | Method for the treatment or prevention of respiratory inflammation with a cyclooxygenase-2 inhibitor in combination with a phosphodiesterase 4 inhibitor and compositions therewith |
| WO2006028830A2 (en) | 2004-09-01 | 2006-03-16 | Euro-Celtique S.A. | Opioid dosage forms having dose proportional steady state cave and auc and less than dose proportional single dose cmax |
| WO2006104703A1 (en) * | 2005-03-29 | 2006-10-05 | Mcneil-Ppc, Inc. | Compositions with hydrophilic drugs in a hydrophobic medium |
| AR054445A1 (es) * | 2005-05-05 | 2007-06-27 | Bristol Myers Squibb Co | Formulaciones de un inhibidor de src/abl |
| US7942818B2 (en) * | 2006-02-01 | 2011-05-17 | University Of Florida Research Foundation, Inc. | Obstetric analgesia system |
| EP2012751A4 (en) | 2006-03-21 | 2010-11-24 | Morehouse School Of Medicine | NEW NANOPARTICLES FOR THE DELIVERY OF ACTIVE AGENTS |
| EP1923053A1 (en) * | 2006-09-27 | 2008-05-21 | Novartis AG | Pharmaceutical compositions comprising nilotinib or its salt |
| JP5284967B2 (ja) | 2007-02-01 | 2013-09-11 | 武田薬品工業株式会社 | 打錠障害を生じない錠剤製剤 |
| FR2963889B1 (fr) * | 2010-08-20 | 2013-04-12 | Debregeas Et Associes Pharma | Formulations a base de nalbuphine et leurs utilisations |
| BR112020002967A2 (pt) | 2017-08-14 | 2020-08-11 | Spruce Biosciences, Inc. | antagonistas de receptor de fator de liberação de corticotropina |
| WO2019036472A1 (en) * | 2017-08-14 | 2019-02-21 | Spruce Biosciences, Inc. | CORTICOTROPIN RELEASE FACTOR RECEPTOR ANTAGONISTS |
| CN108644512B (zh) * | 2018-07-09 | 2023-06-30 | 南京氟源化工管道设备有限公司 | 一种钢衬聚四氟乙烯三通及其模压工艺 |
| AU2019413421B9 (en) * | 2018-12-24 | 2025-02-20 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Treatment use of pyrrolopyrimidine compound, and solid pharmaceutical composition of pyrrolopyrimidine compound |
| EP4175572A4 (en) | 2020-08-12 | 2024-03-27 | Spruce Biosciences, Inc. | Methods and compositions for treating polycystic ovary syndrome |
| US11273128B1 (en) * | 2021-04-15 | 2022-03-15 | Sandoz Ag | Elagolix formulation |
| US11708372B2 (en) | 2021-11-19 | 2023-07-25 | Spruce Biosciences, Inc. | Crystalline composition of tildacerfont and methods of use and preparation thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE10399017I1 (de) * | 1995-02-13 | 2012-05-16 | Searle & Co | Substituierte isoxazole zur Behandlung von entzuendung |
| EP0863134A1 (en) * | 1997-03-07 | 1998-09-09 | Merck Frosst Canada Inc. | 2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2 |
| SA99191255B1 (ar) * | 1998-11-30 | 2006-11-25 | جي دي سيرل اند كو | مركبات سيليكوكسيب celecoxib |
| EP1158977B1 (en) * | 1999-03-10 | 2005-10-12 | G.D. Searle LLC | Composition for administering a cyclooxygenase-2 inhibitor to animals |
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- 2000-12-04 KR KR1020017010031A patent/KR100664479B1/ko not_active Expired - Fee Related
- 2000-12-04 IL IL14476300A patent/IL144763A0/xx active IP Right Grant
- 2000-12-04 JP JP2001543106A patent/JP2003516353A/ja active Pending
- 2000-12-04 CN CNA200510065059XA patent/CN1679556A/zh active Pending
- 2000-12-04 AU AU19303/01A patent/AU1930301A/en not_active Abandoned
- 2000-12-04 PL PL00351069A patent/PL351069A1/xx not_active Application Discontinuation
- 2000-12-04 CA CA002362816A patent/CA2362816C/en not_active Expired - Fee Related
- 2000-12-04 TR TR2001/02297T patent/TR200102297T1/xx unknown
- 2000-12-04 CN CNB008059063A patent/CN1203852C/zh not_active Expired - Fee Related
- 2000-12-04 WO PCT/US2000/032417 patent/WO2001041761A2/en not_active Ceased
- 2000-12-04 HR HR20010582A patent/HRP20010582A2/hr not_active Application Discontinuation
- 2000-12-04 KR KR1020067002453A patent/KR100645866B1/ko not_active Expired - Fee Related
- 2000-12-04 EE EEP200100414A patent/EE200100414A/xx unknown
- 2000-12-06 AU AU19310/01A patent/AU777402B2/en not_active Ceased
- 2000-12-06 CZ CZ20013163A patent/CZ20013163A3/cs unknown
- 2000-12-06 NZ NZ513963A patent/NZ513963A/en unknown
- 2000-12-06 EA EA200100872A patent/EA003639B1/ru not_active IP Right Cessation
- 2000-12-06 AR ARP000106472A patent/AR027896A1/es unknown
- 2000-12-06 EP EP00982254A patent/EP1165072A2/en not_active Ceased
- 2000-12-06 PE PE2000001298A patent/PE20010940A1/es not_active Application Discontinuation
- 2000-12-06 HU HU0200409A patent/HUP0200409A3/hu unknown
- 2000-12-06 US US09/731,349 patent/US20020013357A1/en not_active Abandoned
- 2000-12-06 WO PCT/US2000/032433 patent/WO2001041762A2/en not_active Ceased
- 2000-12-06 HK HK02102619.5A patent/HK1041637A1/zh unknown
- 2000-12-06 SK SK1269-2001A patent/SK12692001A3/sk unknown
- 2000-12-06 MY MYPI20005731A patent/MY138227A/en unknown
- 2000-12-06 TW TW089125989A patent/TWI265808B/zh not_active IP Right Cessation
- 2000-12-11 CO CO00094074A patent/CO5261582A1/es unknown
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2001
- 2001-08-06 IL IL144763A patent/IL144763A/en not_active IP Right Cessation
- 2001-08-07 IS IS6040A patent/IS6040A/is unknown
- 2001-08-08 NO NO20013858A patent/NO20013858L/no not_active Application Discontinuation
- 2001-09-04 BG BG105873A patent/BG105873A/bg unknown
- 2001-09-11 CR CR6458A patent/CR6458A/es not_active Application Discontinuation
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2005
- 2005-01-04 AU AU2005200015A patent/AU2005200015A1/en not_active Abandoned
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