CN120380327A - 荧光强度增强剂、经荧光标记的靶标生物物质的荧光强度增强方法及荧光检测用试剂盒 - Google Patents

荧光强度增强剂、经荧光标记的靶标生物物质的荧光强度增强方法及荧光检测用试剂盒

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Publication number
CN120380327A
CN120380327A CN202380086972.4A CN202380086972A CN120380327A CN 120380327 A CN120380327 A CN 120380327A CN 202380086972 A CN202380086972 A CN 202380086972A CN 120380327 A CN120380327 A CN 120380327A
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China
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group
compound
fluorescence intensity
fluorescent
substituent
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Pending
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CN202380086972.4A
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English (en)
Chinese (zh)
Inventor
白兼研史
中田飞翼
中林淳
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Fujifilm Corp
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Fujifilm Corp
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Publication of CN120380327A publication Critical patent/CN120380327A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1018—Heterocyclic compounds
    • C09K2211/1025—Heterocyclic compounds characterised by ligands
    • C09K2211/1074—Heterocyclic compounds characterised by ligands containing more than three nitrogen atoms as heteroatoms
    • C09K2211/1081—Heterocyclic compounds characterised by ligands containing more than three nitrogen atoms as heteroatoms with sulfur

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN202380086972.4A 2022-12-26 2023-12-25 荧光强度增强剂、经荧光标记的靶标生物物质的荧光强度增强方法及荧光检测用试剂盒 Pending CN120380327A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022-209083 2022-12-26
JP2022209083 2022-12-26
PCT/JP2023/046400 WO2024143263A1 (ja) 2022-12-26 2023-12-25 蛍光強度増強剤、蛍光標識された標的生体物質の蛍光強度増強方法、及び、蛍光検出用キット

Publications (1)

Publication Number Publication Date
CN120380327A true CN120380327A (zh) 2025-07-25

Family

ID=91717891

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380086972.4A Pending CN120380327A (zh) 2022-12-26 2023-12-25 荧光强度增强剂、经荧光标记的靶标生物物质的荧光强度增强方法及荧光检测用试剂盒

Country Status (5)

Country Link
US (1) US20250314658A1 (https=)
EP (1) EP4644874A1 (https=)
JP (1) JPWO2024143263A1 (https=)
CN (1) CN120380327A (https=)
WO (1) WO2024143263A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121522175A (zh) * 2026-01-19 2026-02-13 佛山凯视智能科技有限公司 一种脂蛋白亚型检测用的荧光标记试剂及制备方法与应用

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IE76319B1 (en) 1990-07-23 1997-10-22 Becton Dickinson Co Preservation of cells as controls or standards in cellular analysis
CA2423806C (en) 2000-09-29 2009-12-22 Molecular Probes, Inc. Modified carbocyanine dyes and their conjugates
US20160095939A1 (en) 2014-10-07 2016-04-07 Immunomedics, Inc. Neoadjuvant use of antibody-drug conjugates
JP2012103014A (ja) * 2010-11-05 2012-05-31 Tokyo Metropolitan Institute Of Medical Science 蛍光増強剤および蛍光増強法並びにそれらの利用
GB201220010D0 (en) 2012-11-07 2012-12-19 Oxford Biotherapeutics Ltd Therapeutic amd diagnostic target
JP2014231488A (ja) * 2013-05-28 2014-12-11 片山化学工業株式会社 バイオイメージング用蛍光標識剤
BR112016005802A2 (pt) 2013-09-17 2017-09-12 Blaze Bioscience Inc conjugados de clorotoxina e métodos de seu uso
CN116059395A (zh) 2015-06-29 2023-05-05 第一三共株式会社 用于选择性制造抗体-药物缀合物的方法
EP3324174A4 (en) * 2015-07-13 2019-03-06 Sony Corporation PROCESS FOR IMPROVING LIGHT EMISSION, METHOD FOR DETECTING SUBSTANCES, DEVICE FOR DETECTING SUBSTANCES AND LIGHT EMISSION AMPLIFIERS
RU2731211C1 (ru) 2017-03-21 2020-08-31 Фуджифилм Корпорэйшн Пептидное соединение и способ его получения, композиция для скринингового использования и способ отбора пептидного соединения
JP2019172826A (ja) 2018-03-28 2019-10-10 富士フイルム株式会社 蛍光性化合物及びこれを用いた蛍光標識生体物質
JP7064583B2 (ja) 2018-06-01 2022-05-10 富士フイルム株式会社 蛍光性化合物及びこれを用いた蛍光標識生体物質
KR20210087938A (ko) 2018-09-28 2021-07-13 이미지냅 인코포레이티드 Cd8 이미징 구조체 및 이의 사용 방법
EP3916000B1 (en) 2019-02-28 2026-04-08 FUJIFILM Corporation Method for producing peptide compound, protecting group-forming reagent, and aromatic heterocyclic compound
JP7344982B2 (ja) 2019-11-21 2023-09-14 富士フイルム株式会社 化合物及びこれを用いた蛍光標識生体物質
JP7359869B2 (ja) 2019-12-19 2023-10-11 富士フイルム株式会社 化合物及びこれを用いた蛍光標識生体物質
JP7441306B2 (ja) 2020-04-24 2024-02-29 富士フイルム株式会社 化合物及びこれを用いた標識生体物質
WO2022025210A1 (ja) 2020-07-30 2022-02-03 富士フイルム株式会社 化合物及びこれを用いた標識生体物質
JP7550076B2 (ja) 2021-02-26 2024-09-12 富士フイルム株式会社 蛍光色素及びこれを用いた標識生体物質
JP7837947B2 (ja) 2021-03-08 2026-03-31 富士フイルム株式会社 蛍光性化合物及びこれを用いた蛍光標識生体物質

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121522175A (zh) * 2026-01-19 2026-02-13 佛山凯视智能科技有限公司 一种脂蛋白亚型检测用的荧光标记试剂及制备方法与应用
CN121522175B (zh) * 2026-01-19 2026-03-27 佛山凯视智能科技有限公司 一种脂蛋白亚型检测用的荧光标记试剂及制备方法与应用

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EP4644874A1 (en) 2025-11-05
WO2024143263A1 (ja) 2024-07-04
US20250314658A1 (en) 2025-10-09
JPWO2024143263A1 (https=) 2024-07-04

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