CN120249337A - 细菌人工染色体 - Google Patents

细菌人工染色体 Download PDF

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Publication number
CN120249337A
CN120249337A CN202510130019.6A CN202510130019A CN120249337A CN 120249337 A CN120249337 A CN 120249337A CN 202510130019 A CN202510130019 A CN 202510130019A CN 120249337 A CN120249337 A CN 120249337A
Authority
CN
China
Prior art keywords
cdna
viral
rna
virus
bac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202510130019.6A
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English (en)
Chinese (zh)
Inventor
K·达尔梅尔
J·内茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Original Assignee
Katholieke Universiteit Leuven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven
Publication of CN120249337A publication Critical patent/CN120249337A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CN202510130019.6A 2013-04-26 2014-04-25 细菌人工染色体 Pending CN120249337A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1307528.8A GB201307528D0 (en) 2013-04-26 2013-04-26 Bacterial artificial chromosomes
GB1307528.8 2013-04-26
PCT/EP2014/058459 WO2014174078A1 (en) 2013-04-26 2014-04-25 Bacterial artificial chromosomes
CN201480023688.3A CN105229153A (zh) 2013-04-26 2014-04-25 细菌人工染色体

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201480023688.3A Division CN105229153A (zh) 2013-04-26 2014-04-25 细菌人工染色体

Publications (1)

Publication Number Publication Date
CN120249337A true CN120249337A (zh) 2025-07-04

Family

ID=48626864

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202510130019.6A Pending CN120249337A (zh) 2013-04-26 2014-04-25 细菌人工染色体
CN201480023688.3A Pending CN105229153A (zh) 2013-04-26 2014-04-25 细菌人工染色体

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201480023688.3A Pending CN105229153A (zh) 2013-04-26 2014-04-25 细菌人工染色体

Country Status (17)

Country Link
US (2) US10076564B2 (https=)
EP (2) EP2989205B1 (https=)
JP (1) JP6501756B2 (https=)
KR (1) KR102170609B1 (https=)
CN (2) CN120249337A (https=)
AU (1) AU2014259354B2 (https=)
BR (1) BR112015026531B1 (https=)
DK (1) DK2989205T3 (https=)
ES (1) ES2718187T3 (https=)
GB (1) GB201307528D0 (https=)
HU (1) HUE042886T2 (https=)
PL (1) PL2989205T3 (https=)
PT (1) PT2989205T (https=)
SI (1) SI2989205T1 (https=)
TR (1) TR201904215T4 (https=)
WO (1) WO2014174078A1 (https=)
ZA (1) ZA201507795B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201716307D0 (en) 2017-10-05 2017-11-22 Univ Leuven Kath Chimeric yellow fever zika virus strain
GB201716254D0 (en) * 2017-10-05 2017-11-22 Univ Leuven Kath Live-attenuated flaviruses with heterologous antigens
WO2019204654A1 (en) * 2018-04-18 2019-10-24 Utah State University Compositions and methods for zika virus characterization and vaccine development
GB201814563D0 (en) 2018-09-07 2018-10-24 Univ Leuven Kath Chimeric flavivirus lyssavirus vaccines
US20220168412A1 (en) 2019-04-10 2022-06-02 Katholieke Universiteit Leuven Chimeric Zika-Japanese Encephalitis Virus
CN114728054A (zh) 2019-09-13 2022-07-08 勒芬天主教大学 拉沙病毒疫苗
EP4041301A1 (en) 2019-09-13 2022-08-17 Katholieke Universiteit Leuven Chimeric filovirus vaccines
CN114450408A (zh) * 2019-09-25 2022-05-06 鲁汶天主教大学 大载体和用于高产量生产的方法
CA3168673A1 (en) * 2020-02-27 2021-09-02 Kai DALLMEIER Coronavirus vaccines
WO2025012350A1 (en) * 2023-07-11 2025-01-16 Virovet Nv Vectors expressing attenuated rna virus of the family arteriviridae and uses thereof
WO2025171062A1 (en) * 2024-02-06 2025-08-14 The Regents Of The University Of California iMODULON GENE CLUSTERS AND METHODS TO IDENTIFY AND USE SAME

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665600A (en) 1991-09-18 1997-09-09 Research Corporation Technologies, Inc. Pichia pastoris linear plasmids and DNA fragments thereof
US5866404A (en) 1995-12-06 1999-02-02 Yale University Yeast-bacteria shuttle vector
US6962708B1 (en) 1997-02-28 2005-11-08 Acambis, Inc. Chimeric flavivirus vaccines
US5874259A (en) * 1997-11-21 1999-02-23 Wisconsin Alumni Research Foundation Conditionally amplifiable BAC vector
WO2000034497A2 (en) 1998-12-09 2000-06-15 The General Hospital Corporation Enhanced packaging of herpes virus amplicons and generation of recombinant virus vectors
ES2170622B1 (es) 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
GB2372991B (en) * 2001-03-09 2004-11-17 Fiocruz Fundacao Oswaldo Cruz Flavivirus expression vector
US6472177B1 (en) 2001-04-23 2002-10-29 Wisconsin Alumni Research Foundation Expression vector with dual control of replication and transcription
US6864087B2 (en) * 2001-07-31 2005-03-08 Wisconsin Alumni Research Foundation Method for converting single-copy BAC vectors to conditional high-copy pBAC/oriHC vectors
US20050106733A1 (en) 2001-12-25 2005-05-19 Kenzo Takada Double-stranded cyclic dna capable of proliferating as a bacterial e coli chromosome
WO2004033633A2 (en) 2002-10-04 2004-04-22 Embiosis Pharmaceuticals Compatible host/vector systems for expression of dna
WO2005042014A1 (en) 2003-10-29 2005-05-12 The University Of Queensland West nile virus vaccine
US20050214838A1 (en) 2004-03-10 2005-09-29 Waclaw Szybalski Methods for mapping and sequencing nucleic acids
WO2009053988A1 (en) 2007-10-25 2009-04-30 Ramot At Tel-Aviv University Ltd. Production of bac vectors carrying viral genomes
CN101864442A (zh) 2010-05-19 2010-10-20 江苏省农业科学院 重组火鸡疱疹病毒细菌人工染色体转移载体

Also Published As

Publication number Publication date
AU2014259354B2 (en) 2020-02-27
SI2989205T1 (sl) 2019-05-31
WO2014174078A1 (en) 2014-10-30
EP2989205B1 (en) 2019-01-02
AU2014259354A1 (en) 2015-11-05
EP2989205A1 (en) 2016-03-02
ZA201507795B (en) 2019-07-31
EP3540065A1 (en) 2019-09-18
GB201307528D0 (en) 2013-06-12
US10076564B2 (en) 2018-09-18
CN105229153A (zh) 2016-01-06
ES2718187T3 (es) 2019-06-28
JP2016518132A (ja) 2016-06-23
US20190111125A1 (en) 2019-04-18
BR112015026531A2 (https=) 2017-09-05
PT2989205T (pt) 2019-04-23
PL2989205T3 (pl) 2019-06-28
KR102170609B1 (ko) 2020-10-28
HUE042886T2 (hu) 2019-07-29
KR20160003032A (ko) 2016-01-08
BR112015026531B1 (pt) 2023-02-07
TR201904215T4 (tr) 2019-04-22
US20160206723A1 (en) 2016-07-21
DK2989205T3 (en) 2019-04-23
JP6501756B2 (ja) 2019-04-17

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