CN120093910A - Dpp3活性抑制剂、包含其的药物组合物及其用途 - Google Patents

Dpp3活性抑制剂、包含其的药物组合物及其用途 Download PDF

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Publication number
CN120093910A
CN120093910A CN202510254123.6A CN202510254123A CN120093910A CN 120093910 A CN120093910 A CN 120093910A CN 202510254123 A CN202510254123 A CN 202510254123A CN 120093910 A CN120093910 A CN 120093910A
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China
Prior art keywords
dpp3
disease
antibody
inhibitor
dpp
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CN202510254123.6A
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Chinese (zh)
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安德烈亚斯·伯格曼
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Yishuangfu Pharmaceutical Co ltd
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Yishuangfu Pharmaceutical Co ltd
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
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CN202510254123.6A 2016-04-21 2017-04-20 Dpp3活性抑制剂、包含其的药物组合物及其用途 Pending CN120093910A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP16166476 2016-04-21
EP16166476.8 2016-04-21
PCT/EP2017/059377 WO2017182561A1 (en) 2016-04-21 2017-04-20 Methods for determining dpp3 and therapeutic methods
CN201780039077.1A CN110168372A (zh) 2016-04-21 2017-04-20 用于确定dpp3的方法和治疗方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201780039077.1A Division CN110168372A (zh) 2016-04-21 2017-04-20 用于确定dpp3的方法和治疗方法

Publications (1)

Publication Number Publication Date
CN120093910A true CN120093910A (zh) 2025-06-06

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Family Applications (3)

Application Number Title Priority Date Filing Date
CN202510254123.6A Pending CN120093910A (zh) 2016-04-21 2017-04-20 Dpp3活性抑制剂、包含其的药物组合物及其用途
CN201780039077.1A Pending CN110168372A (zh) 2016-04-21 2017-04-20 用于确定dpp3的方法和治疗方法
CN202511191873.XA Pending CN120992960A (zh) 2016-04-21 2017-04-20 诊断及监测伴有坏死过程或与坏死过程相关的对象的疾病或病症的方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201780039077.1A Pending CN110168372A (zh) 2016-04-21 2017-04-20 用于确定dpp3的方法和治疗方法
CN202511191873.XA Pending CN120992960A (zh) 2016-04-21 2017-04-20 诊断及监测伴有坏死过程或与坏死过程相关的对象的疾病或病症的方法

Country Status (15)

Country Link
US (3) US20190145981A1 (https=)
EP (5) EP3446125B1 (https=)
JP (4) JP2019520550A (https=)
KR (3) KR102565453B1 (https=)
CN (3) CN120093910A (https=)
AU (1) AU2017252212B2 (https=)
BR (1) BR112018071583A2 (https=)
CA (2) CA3264486A1 (https=)
CH (1) CH713803B1 (https=)
DE (1) DE112017002105T5 (https=)
IL (1) IL262472B2 (https=)
MX (3) MX2018012856A (https=)
MY (1) MY200300A (https=)
SG (1) SG11201809252YA (https=)
WO (1) WO2017182561A1 (https=)

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AU2017252212B2 (en) * 2016-04-21 2023-09-07 4TEEN4 Pharmaceuticals GmbH Methods for determining DPP3 and therapeutic methods
MY202502A (en) * 2017-10-25 2024-05-01 4TEEN4 Pharmaceuticals GmbH Dpp3 binder directed to and binding to specific dpp3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress
WO2020128039A2 (en) * 2018-12-21 2020-06-25 4TEEN4 Pharmaceuticals GmbH Therapy guidance and/or therapy monitoring for a treatment with angiotensin-receptor-agonist and/or a precursor thereof
BR112022002856A2 (pt) * 2019-08-30 2022-08-09 4TEEN4 Pharmaceuticals GmbH Orientação de terapia e/ou monitoramento de terapia para o tratamento de choque
MX2022010564A (es) 2020-02-27 2022-11-30 Adrenomed Ag Aglutinante anti-adrenomedulina (adm) para usarse en terapia de pacientes en choque.
CA3168978A1 (en) * 2020-02-27 2021-09-02 Andreas Bergmann Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock
CN115244401A (zh) * 2020-02-27 2022-10-25 4Teen4制药有限公司 用于在休克患者中进行nt-adm抗体的治疗指导、监测和分层的dpp3
EP3922993A1 (en) 2020-06-12 2021-12-15 4TEEN4 Pharmaceuticals GmbH Dpp3 in patients infected with coronavirus
WO2021185786A1 (en) 2020-03-16 2021-09-23 4TEEN4 Pharmaceuticals GmbH Dpp3 in patients infected with coronavirus
CA3254142A1 (en) 2022-03-15 2023-09-21 Adrenomed Ag STABLE AQUEOUS FORMULATION OF AN ANTI-ADRENOMEDULLIN (ADM) ANTIBODY OR AN ANTI-ADM ANTIBODY FRAGMENT
CN117186177B (zh) * 2022-05-31 2024-08-23 中国农业大学 一种具有降尿酸活性的鸭血球蛋白肽及其制备方法
KR20250042158A (ko) 2022-07-29 2025-03-26 아드레노메드 아게 쇼크의 요법 또는 예방에 사용하기 위한 항-아드레노메둘린 (ADM) 항체 또는 항-ADM 항체 단편 또는 항-ADM 비-Ig 스캐폴드
CN119630969A (zh) 2022-07-29 2025-03-14 4Teen4制药有限公司 预测患有败血症性休克的患者中的dpp3增加
CN120359042A (zh) 2022-12-15 2025-07-22 4Teen4制药有限公司 改善危重病患者肺功能的dpp3抑制剂
CN115804836A (zh) * 2022-12-27 2023-03-17 中国人民解放军海军特色医学中心 一种中枢小分子蛋白dpp3在制备降压药物中的应用
WO2024200862A1 (en) 2023-03-29 2024-10-03 4TEEN4 Pharmaceuticals GmbH Dpp3 inhibitor for myocardial protection and prevention of myocardial injury in critically ill patients with blood pressure decline
WO2026046947A1 (en) 2024-08-26 2026-03-05 4TEEN4 Pharmaceuticals GmbH Anti-dpp3 antibody directed to and binding to dpp3 for the treatment of shock in extreme-critically ill patients
WO2026046968A1 (en) 2024-08-26 2026-03-05 4TEEN4 Pharmaceuticals GmbH Dpp3 binders for the treatment of endothelial dysfunction

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