CN119630776A - 包含微小有用物质的液体的纯化浓缩装置、以及使用了该装置的微小有用物质的纯化浓缩液的制造方法 - Google Patents

包含微小有用物质的液体的纯化浓缩装置、以及使用了该装置的微小有用物质的纯化浓缩液的制造方法 Download PDF

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Publication number
CN119630776A
CN119630776A CN202380057331.6A CN202380057331A CN119630776A CN 119630776 A CN119630776 A CN 119630776A CN 202380057331 A CN202380057331 A CN 202380057331A CN 119630776 A CN119630776 A CN 119630776A
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CN
China
Prior art keywords
liquid
tank
purification
hollow fiber
fiber membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN202380057331.6A
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English (en)
Chinese (zh)
Inventor
昌子弘一
佐藤浩志
中冢修志
内村诚一
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Daicel Corp
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Daicel Corp
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Publication date
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Publication of CN119630776A publication Critical patent/CN119630776A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Water Supply & Treatment (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
CN202380057331.6A 2022-07-28 2023-06-19 包含微小有用物质的液体的纯化浓缩装置、以及使用了该装置的微小有用物质的纯化浓缩液的制造方法 Pending CN119630776A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022-120666 2022-07-28
JP2022120666 2022-07-28
PCT/JP2023/022644 WO2024024336A1 (ja) 2022-07-28 2023-06-19 微小有用物質を含む液の精製濃縮装置及びそれを用いた微小有用物質の精製濃縮液の製造方法

Publications (1)

Publication Number Publication Date
CN119630776A true CN119630776A (zh) 2025-03-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380057331.6A Pending CN119630776A (zh) 2022-07-28 2023-06-19 包含微小有用物质的液体的纯化浓缩装置、以及使用了该装置的微小有用物质的纯化浓缩液的制造方法

Country Status (5)

Country Link
EP (1) EP4563686A1 (cg-RX-API-DMAC7.html)
JP (1) JPWO2024024336A1 (cg-RX-API-DMAC7.html)
KR (1) KR20250048002A (cg-RX-API-DMAC7.html)
CN (1) CN119630776A (cg-RX-API-DMAC7.html)
WO (1) WO2024024336A1 (cg-RX-API-DMAC7.html)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2788780B1 (fr) * 1999-01-27 2001-03-30 Ap Cells Inc Procede de preparation de vesicules membranaires
CN101967091A (zh) * 2009-07-28 2011-02-09 凯发知识产权资源私人有限公司 用于有机酸提纯的方法
JP6081290B2 (ja) 2012-05-22 2017-02-15 ダイセン・メンブレン・システムズ株式会社 内圧式の中空糸型ｎｆ膜とその製造方法
JP7043125B2 (ja) 2016-10-28 2022-03-29 旭化成メディカル株式会社 連続培養における有用物質の回収方法
US11714068B2 (en) * 2018-07-31 2023-08-01 Mie University Exosome production method
JP7513869B2 (ja) 2020-03-23 2024-07-10 澁谷工業株式会社 エクソソーム抽出装置およびエクソソームの抽出方法
WO2021235168A1 (ja) 2020-05-19 2021-11-25 ダイセン・メンブレン・システムズ株式会社 チューブラー型分離膜とそれを含むチューブラー型分離膜モジュール

Also Published As

Publication number Publication date
KR20250048002A (ko) 2025-04-07
JPWO2024024336A1 (cg-RX-API-DMAC7.html) 2024-02-01
EP4563686A1 (en) 2025-06-04
WO2024024336A1 (ja) 2024-02-01

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