CN1190437A - 骨刺激因子 - Google Patents

骨刺激因子 Download PDF

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Publication number
CN1190437A
CN1190437A CN96194594A CN96194594A CN1190437A CN 1190437 A CN1190437 A CN 1190437A CN 96194594 A CN96194594 A CN 96194594A CN 96194594 A CN96194594 A CN 96194594A CN 1190437 A CN1190437 A CN 1190437A
Authority
CN
China
Prior art keywords
polypeptide
seq
amino acid
acid sequence
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN96194594A
Other languages
English (en)
Chinese (zh)
Inventor
彻克·兴·泰姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GIENSY REGENERATION SCIENCE CO
Original Assignee
GIENSY REGENERATION SCIENCE CO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GIENSY REGENERATION SCIENCE CO filed Critical GIENSY REGENERATION SCIENCE CO
Publication of CN1190437A publication Critical patent/CN1190437A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN96194594A 1995-06-07 1996-06-07 骨刺激因子 Pending CN1190437A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/487,074 1995-06-07
US08/487,074 US5880094A (en) 1995-06-07 1995-06-07 Polypeptides that stimulate bone growth

Publications (1)

Publication Number Publication Date
CN1190437A true CN1190437A (zh) 1998-08-12

Family

ID=23934300

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96194594A Pending CN1190437A (zh) 1995-06-07 1996-06-07 骨刺激因子

Country Status (18)

Country Link
US (1) US5880094A (enExample)
EP (1) EP0832221A1 (enExample)
JP (1) JPH11506337A (enExample)
KR (1) KR19990022716A (enExample)
CN (1) CN1190437A (enExample)
AU (1) AU6117996A (enExample)
BR (1) BR9608614A (enExample)
CA (1) CA2222789A1 (enExample)
CZ (1) CZ389397A3 (enExample)
HU (1) HUP9802589A3 (enExample)
IL (1) IL118598A0 (enExample)
IN (1) IN185705B (enExample)
NO (1) NO975565L (enExample)
NZ (1) NZ310391A (enExample)
PL (1) PL326357A1 (enExample)
TW (1) TW469273B (enExample)
WO (1) WO1996040909A1 (enExample)
ZA (1) ZA964821B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1065876C (zh) * 1998-07-22 2001-05-16 南京医科大学 细胞骨架样基因的编码蛋白特异性抗体

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786327A (en) 1993-03-12 1998-07-28 Gensci Regeneration Sciences Inc. Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same
US6352973B1 (en) 1995-06-07 2002-03-05 Osteopharm Inc. Bone stimulating factor
US6117839A (en) * 1995-06-07 2000-09-12 Gensci Regeneration Sciences, Inc. Bone stimulating factor
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor
US6815421B1 (en) * 2001-03-22 2004-11-09 Osteopharm Inc. Polypeptides for use in ameliorating effects of aging in mammals
US20060052307A1 (en) * 2002-12-05 2006-03-09 Tam Cherk S Bone growth factor
DE10332011A1 (de) * 2003-07-14 2005-02-17 Schott Ag Verwendung von Glaszusammensetzungen zum Erzielen eines antioxidativen Effektes
US7399826B1 (en) 2003-10-02 2008-07-15 Ali Sadat M Peptide for promoting healing of fractures
WO2006007682A1 (en) * 2004-07-19 2006-01-26 Osteopharm Inc. Polypeptides for use in ameliorating effects of aging in mammals

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3051160B2 (ja) * 1988-12-08 2000-06-12 ノバルティス・アクチエンゲゼルシャフト 好中球活性化ペプチド‐２
US5461034A (en) * 1989-02-23 1995-10-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenic growth polypeptides identified from regenerating bone marrow
US5578569A (en) * 1993-03-12 1996-11-26 Tam; Cherk S. Method of increasing bone growth
IL108947A0 (en) * 1993-03-12 1994-06-24 Osteopharm Ltd Bone stimulating factor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1065876C (zh) * 1998-07-22 2001-05-16 南京医科大学 细胞骨架样基因的编码蛋白特异性抗体

Also Published As

Publication number Publication date
HUP9802589A3 (en) 2000-10-30
BR9608614A (pt) 1999-12-07
NZ310391A (en) 2001-03-30
PL326357A1 (en) 1998-09-14
NO975565D0 (no) 1997-12-03
TW469273B (en) 2001-12-21
IL118598A0 (en) 1996-10-16
NO975565L (no) 1998-01-19
AU6117996A (en) 1996-12-30
HUP9802589A2 (hu) 1999-03-29
EP0832221A1 (en) 1998-04-01
JPH11506337A (ja) 1999-06-08
MX9709618A (es) 1998-10-31
KR19990022716A (ko) 1999-03-25
CA2222789A1 (en) 1996-12-19
ZA964821B (en) 1997-02-11
US5880094A (en) 1999-03-09
WO1996040909A1 (en) 1996-12-19
IN185705B (enExample) 2001-04-14
CZ389397A3 (cs) 1998-05-13

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication