CN1189342A - Medicine for treating scar, acne, brandy nose and pigmentation and its prepn. method - Google Patents

Medicine for treating scar, acne, brandy nose and pigmentation and its prepn. method Download PDF

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CN1189342A
CN1189342A CN96102894A CN96102894A CN1189342A CN 1189342 A CN1189342 A CN 1189342A CN 96102894 A CN96102894 A CN 96102894A CN 96102894 A CN96102894 A CN 96102894A CN 1189342 A CN1189342 A CN 1189342A
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parts
semen
fructus
rhizoma
medicine
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CN1054297C (en
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陈希胜
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Abstract

A medicine in the form of ointment for curing scar, acne, brandy nose and pigmentation is prepared from 27 Chinese-medicinal materials such as limonite, barley, glutinous rice, ampelopsis root, tribulus fruit, etc. through crushing, immersion, filter, concentration and addition of assistants, and features 100% effective rate and 95% curative rate.

Description

A kind of medicine for the treatment of cicatrix, acne, rosacea, pigementation and preparation method thereof
The present invention relates to a kind of Chinese crude drug and be the medicine of treatment cicatrix, acne, rosacea and pigementation that raw material makes and prepare the method for this medicine.
Because early stage hypertrophic cicatrix that wound, burn, operation healing cause and acne, rosacea are common dermatopathies.Often bring the very big misery of health and spiritual aspect to people.For the clinical externally applied anti-inflammation western medicines of using of this type of disease more.Also there are some cosmetics can slow down inflammation, " the close beautiful cicatrix spirit " that the Henan Province Mi County elixir of life laboratory of for example selling on the market is produced with therapeutic efficiency.But do not see the introduction of its main component.Other has 91106622.5 applications for a patent for invention " a kind of manufacture method of controlling the cicatrix tincture " disclosed is by Scolopendra, and Galla Chinensis, Fructus Bruceae etc. amount to the external-use tincture with treatment cicatrix effect that 30 flavor Chinese medicines are made for main component.
The purpose of this invention is to provide a kind of is the medicine for external use with treatment cicatrix, acne, rosacea effect that raw material is made with the Chinese crude drug.Another object of the present invention also is to disclose the preparation method of this medicine.
The present invention is achieved by the following scheme, selecting the Chinese crude drug of blood circulation promoting and blood stasis dispelling dredge the meridian passage is raw material, has the medicine for the treatment of cicatrix, pigementation, acne, rosacea effect by the theory of Chinese medical science prescription and through processing, pulverize, flood, filter, concentrate to be prepared into.
Major technique of the present invention thes contents are as follows:
One, medicine of the present invention is made (consumption is a weight portion) by following component:
Limonitum 50-100 part Radix Et Rhizoma Rhei 12-25 part
Fructus Hordei Vulgaris 50-100 part Radix Rhodiolae 12-25 part
Oryza glutinosa 50-100 part Thallus Laminariae (Thallus Eckloniae) 12-25 part
Egg ointment 50-100 part Rhizoma Cimicifugae 12-25 part
Hold back 50-100 part Fructus Gardeniae 12-25 part in vain
Fructus Tribuli 50-100 part Rhizoma Dioscoreae 12-25 part
Semen Abutili 50-100 part Poria 12-25 part
Radix Angelicae Dahuricae 50-100 part Semen Benincasae 12-25 part
Herba Portulacae 50-100 part Fructus Lycii 12-25 part
Bombyx Batryticatus 50-100 part Rhizoma Cyperi 12-25 part
Fructus Ilicis Purpureae 50-100 part Semen Armeniacae Amarum 12-25 part
Borneolum Syntheticum 50-100 part Semen Persicae 12-25 part
Rhizoma Atractylodis Macrocephalae 50-100 part Semen Cuscutae 12-25 part
White sucrose 25-50 part
Two, medicine optimum weight proportioning of the present invention is:
12 parts of 50 parts of Radix Et Rhizoma Rhei of Limonitum
12 parts of 50 parts of Radix Rhodiolaes of Fructus Hordei Vulgaris
12 parts of 50 parts of Thallus Laminariae (Thallus Eckloniae)s of Oryza glutinosa
12 parts of 50 parts of Rhizoma Cimicifugaes of egg ointment
Hold back 12 parts of 50 parts of Fructus Gardeniae in vain
12 parts of 50 portions of Rhizoma Dioscoreaes of Fructus Tribuli
12 parts of 50 parts of Porias of Semen Abutili
12 parts of 50 parts of Semen Benincasaes of the Radix Angelicae Dahuricae
12 parts of 50 parts of Fructus Lycii of Herba Portulacae
12 parts of 50 parts of Rhizoma Cyperi of Bombyx Batryticatus
12 parts in 50 parts of Semen Armeniacae Amarums of Fructus Ilicis Purpureae
12 parts in 50 parts of Semen Persicaes of Borneolum Syntheticum
12 parts of 50 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
25 parts of white sucrose
Three, the preparation method of medicine of the present invention:
1, grinding and processing:
Get Limonitum and be ground into the fine-powdered that to pass through No. three sieves;
Get the coarse grain that Fructus Hordei Vulgaris powder is broken into by a sieve and get final product, after cook, dry, pulverizing slightly;
Be transparent faint yellow gluey piece after Oryza glutinosa cooked, dries, pulverize slightly;
Semen Cuscutae is washed the back oven dry;
With Fructus Tribuli, Semen Abutili, Rhizoma Cyperi, Semen Armeniacae Amarum, Semen Persicae, Fructus Ilicis Purpureae, Bombyx Batryticatus, Semen Benincasae, fragmentation ,-broken be four to get final product;
With the Rhizoma Atractylodis Macrocephalae, the Radix Angelicae Dahuricae, hold back in vain, Rhizoma Cimicifugae, Radix Et Rhizoma Rhei, Radix Rhodiolae, Rhizoma Dioscoreae, Poria be crushed to thumbnail size and get final product;
Herba Portulacae, Fructus Gardeniae, Thallus Laminariae (Thallus Eckloniae), Fructus Lycii pulverized slightly get final product.
Make the egg ointment: egg is boiled peel off shell and albumen, egg yolk is put in the iron pan done stir-fry with big fire.Egg yolk is fried to slightly being clamminess and oil is inclined to when fuel-displaced, continues to fry to fuel-displaced again, and oil is inclined to.Incline altogether and three oil and mix into the egg ointment.Frying black egg yolk slag discards.
2, dipping:
With the Limonitum, Fructus Hordei Vulgaris, the Oryza glutinosa that crush, hold back in vain, Fructus Tribuli, Semen Abutili, the Radix Angelicae Dahuricae, Herba Portulacae, Bombyx Batryticatus, Fructus Ilicis Purpureae, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Radix Rhodiolae, Thallus Laminariae (Thallus Eckloniae), Rhizoma Cimicifugae, Fructus Gardeniae, Rhizoma Dioscoreae, Poria, Semen Benincasae, Fructus Lycii, Rhizoma Cyperi, Semen Armeniacae Amarum, Semen Persicae, Semen Cuscutae 24 flavor Chinese medicines mix in jar, adding concentration is 60% alcohol solution dipping, amount of alcohol added is submergence Chinese medicine and surpasses 1/5 of volume, amount to and soaked 120 hours, extracted a medicinal liquid in per 24 hours, and added 60% alcoholic solution after the extraction to original total amount.Extract medicinal liquid altogether five times.Flood the waste that finishes.
3, filter:
With precipitating through 48 hours after the mixing of five extraction medicinal liquids, by filter square-bottomed bamboo basket, the various impurity of elimination.
4, concentrate:
Filtered liquid medicine is poured in the round-bottomed flask that has condensation reflux unit, bottle is placed in the water-bath heats, reclaim the ethanol that steams, the Chinese medicine fluid extract after must concentrating in the flask by the water condensation reflux.
5, system ointment:
The Chinese medicine fluid extract is heated to the white sucrose of crack back adding is stirred to dissolving.Adding each analog assistant then successively stirs.Again Borneolum Syntheticum is pulverized the back and is added and stir, add then the egg ointment stir medicine externally-applied ointment of the present invention.
The auxiliary agent for preparing externally-applied ointment adding of the present invention has thickening agent, wetting agent, antiseptic, spice etc.The auxiliary agent product of selecting for use and the weight proportion of adding following (with respect to the percentage by weight of Chinese medicine fluid extract):
Sodium Tvlose 4-6%
Glycerol 15-20%
Chlorobutanol 0.1-0.2%
Benzoic acid 0.5-1%
Vanillin 0.5-1%
Drug ointment of the present invention is the light yellow strong Borneolum Syntheticum fragrance that has, and stronger stability is arranged, effect duration 2-3.Can play and make muscular tissue under the cicatrix epidermis in order, further recover blood capillary and pore, have effects such as antiinflammatory, can reach dispeling scar, the purpose of dermatopathies such as treatment acne, pigementation, rosacea.
24 hours continuous uses of dispeling scar, better effects if directly is coated on the cicatrix, one day three times, 15 days is a course of treatment, each course of treatment intermediate phase every 4-7 days, can recover normal skin general 1-3 course of treatment substantially, it is better to wrap up the scar effect of dispelling with gauze.
The treatment acne once is applied to every night can fully recover in the general 1-7 in affected part days.
Dispel the rosacea patient and answer alleviating alcohol addiction, medicine of the present invention is applied to the affected part, continuous use can be fully recovered in general about 7 days in 24 hours, at present through clinic trial, and 200 of patients, at minimum 5 years old of age, maximum 52 years old, effective percentage reached 100%, cure rate about 95%.Particularly the cicatrix that causes of adversary's postoperative, knife injury has the curative effect of special pearl.
The selected raw material of medicine of the present invention can be got along amiably and peacefully after being compatibility, no incompatibility phenomenon, nontoxic, the side effect of the ointment of making.
Medicine of the present invention also can be made into crust patch, liquid varnish, adopts the processing method of pharmacopeia regulation to get final product.
Embodiment:
One, component and weight proportion:
Limonitum 50 gram Radix Et Rhizoma Rhei 12 grams
Fructus Hordei Vulgaris 50 gram Radix Rhodiolaes 12 grams
Oryza glutinosa 50 gram Thallus Laminariae (Thallus Eckloniae)s 12 grams
Egg ointment 50 gram liters fiber crops 12 grams
Hold back 50 gram Fructus Gardeniae, 12 grams in vain
Fructus Tribuli 50 Keshan medicines 12 grams
Semen Abutili 50 gram Porias 12 grams
The Radix Angelicae Dahuricae 50 gram Semen Benincasaes 12 grams
Herba Portulacae 50 gram Fructus Lycii 12 grams
Bombyx Batryticatus 50 gram Rhizoma Cyperi 12 grams
Fructus Ilicis Purpureae 50 gram Semen Armeniacae Amarums 12 grams
Borneolum Syntheticum 50 gram Semen Persicaes 12 grams
The Rhizoma Atractylodis Macrocephalae 50 gram Semen Cuscutae 12 grams
White sucrose 25 grams
Two, preparation method:
1, grinding and processing:
By after the above-mentioned weight proportion weighing;
Limonitum is ground into can be by No. three sieve fine powders;
Be ground into as the Fructus Jujubae bulk after cooking, dry after Fructus Hordei Vulgaris powder being broken into coarse grain;
Be crushed to the Fructus Jujubae bulk after Oryza glutinosa cooked, dries;
Semen Cuscutae is washed the back oven dry;
With Fructus Tribuli, Semen Abutili, Rhizoma Cyperi, Semen Armeniacae Amarum, Semen Persicae, Fructus Ilicis Purpureae, Bombyx Batryticatus, Semen Benincasae, broken one broken be four to get final product;
With the Rhizoma Atractylodis Macrocephalae, the Radix Angelicae Dahuricae, hold back in vain, Rhizoma Cimicifugae, Radix Et Rhizoma Rhei, Radix Rhodiolae, Rhizoma Dioscoreae, Poria be crushed to thumbnail size and get final product;
Herba Portulacae, Fructus Gardeniae, Thallus Laminariae (Thallus Eckloniae), Fructus Lycii are pulverized slightly;
Egg boiled peel off shell and albumen, egg yolk is put in the iron pan to do with big fire fry.Egg yolk is fried to slightly being clamminess and oil is inclined to when fuel-displaced, continues to fry to fuel-displaced again, and oil is inclined to.Incline altogether three oil and mix egg ointment 50g.Frying black egg yolk slag discards.
2, dipping:
Above-mentioned 24 flavor (the not comprising the egg ointment) medical materials that crush are mixed in jar, and adding concentration is that 60% alcoholic solution 5000ml soaks, not go out medical material 1/5, flooded 120 hours, extracted a medicinal liquid in per 24 hours, and added 60% alcoholic solution then, each additional amount equals extracted amount.Extract medicinal liquid 5000ml altogether, flood the waste that finishes.
3, filter:
5000ml extracted leave standstill 48 hours post precipitations after medicinal liquid mixes by filter square-bottomed bamboo basket, elimination impurity.
4, concentrate:
Filtrate pouring into had in the round-bottomed flask of condensation reflux unit, be placed in the water-bath and heat, reclaim ethanol 2382ml, get Chinese medicine fluid extract 1608 grams by the water condensation reflux.
5, system ointment:
The Chinese medicine fluid extract is put into material-compound tank, be heated on water-soluble crackly, add white sucrose 25 grams, be stirred to dissolving.80 gram Sodium Tvlose and 300 are restrained glycerol mix to add then in the Chinese medicine fluid extract and stir, can fully dissolve after about one hour.Add 2 gram chlorobutanols then successively and stir, add 8 gram benzoic acid and stir, add 8 gram vanillin and stir, add Borneolum Syntheticum 50 grams that are ground into fine powder and stir, add egg ointment 50 grams and stir and promptly get medicine externally-applied ointment of the present invention.

Claims (5)

1, a kind of medicine for the treatment of cicatrix, acne, rosacea, pigementation is characterized in that it is the medicine of being made by the following weight proportion raw material:
Limonitum 50-100 part Radix Et Rhizoma Rhei 12-25 part
Fructus Hordei Vulgaris 50-100 part Radix Rhodiolae 12-25 part
Oryza glutinosa 50-100 part Thallus Laminariae (Thallus Eckloniae) 12-25 part
Egg ointment 50-100 part Rhizoma Cimicifugae 12-25 part
Hold back 50-100 part Fructus Gardeniae 12-25 part in vain
Fructus Tribuli 50-100 part Rhizoma Dioscoreae 12-25 part
Semen Abutili 50-100 part Poria 12-25 part
Radix Angelicae Dahuricae 50-100 part Semen Benincasae 12-25 part
Herba Portulacae 50-100 part Fructus Lycii 12-25 part
Bombyx Batryticatus 50-100 part Rhizoma Cyperi 12-25 part
Fructus Ilicis Purpureae 50-100 part Semen Armeniacae Amarum 12-25 part
Borneolum Syntheticum 50-100 part Semen Persicae 12-25 part
Rhizoma Atractylodis Macrocephalae 50-100 part Semen Cuscutae 12-25 part
White sucrose 25-50 part
2, a kind of medicine for the treatment of cicatrix, acne, rosacea, pigementation according to claim 1, wherein the weight proportion of each raw material is
12 parts of 50 parts of Radix Et Rhizoma Rhei of Limonitum
12 parts of 50 parts of Radix Rhodiolaes of Fructus Hordei Vulgaris
12 parts of 50 parts of Thallus Laminariae (Thallus Eckloniae)s of Oryza glutinosa
12 parts of 50 parts of Rhizoma Cimicifugaes of egg ointment
Hold back 12 parts of 50 parts of Fructus Gardeniae in vain
12 parts of 50 portions of Rhizoma Dioscoreaes of Fructus Tribuli
12 parts of 50 parts of Porias of Semen Abutili
12 parts of 50 parts of Semen Benincasaes of the Radix Angelicae Dahuricae
12 parts of 50 parts of Fructus Lycii of Herba Portulacae
12 parts of 50 parts of Rhizoma Cyperi of Bombyx Batryticatus
12 parts in 50 parts of Semen Armeniacae Amarums of Fructus Ilicis Purpureae
12 parts in 50 parts of Semen Persicaes of Borneolum Syntheticum
12 parts of 50 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
25 parts of white sucrose
3, a kind of medicine for the treatment of cicatrix, acne, rosacea, pigementation according to claim 1 and 2 is characterized in that this medicine adds auxiliary agent and can be made into externally-applied ointment.
4, a kind of medicine for the treatment of cicatrix, acne, rosacea, pigementation according to claim 3 is characterized in that the auxiliary agent and the proportioning following (with respect to the percentage by weight of Chinese medicine fluid extract) that add:
Sodium Tvlose 4-6%
Glycerol 15-20%
Chlorobutanol 0.1-0.2%
Benzoic acid 0.5-1%
Vanillin 0.5-1%
5, a kind of medicine for the treatment of cicatrix, acne, rosacea, pigementation according to claim 3 is characterized in that this medicine prepares as follows:
(1) grinding and processing:
Get Limonitum and be ground into the fine-powdered that to pass through No. three sieves;
Get Fructus Hordei Vulgaris powder be broken into by No. one the sieve coarse grain get final product, after cook, dry after slightly the pulverizing.
Be transparent faint yellow gluey piece after Oryza glutinosa cooked, dries, pulverize slightly;
Semen Cuscutae is washed the back oven dry;
With Fructus Tribuli, Semen Abutili, Rhizoma Cyperi, Semen Armeniacae Amarum, Semen Persicae, Fructus Ilicis Purpureae, Bombyx Batryticatus, Semen Benincasae, fragmentation-broken is four to get final product;
With the Rhizoma Atractylodis Macrocephalae, the Radix Angelicae Dahuricae, hold back in vain, Rhizoma Cimicifugae, Radix Et Rhizoma Rhei, Radix Rhodiolae, Rhizoma Dioscoreae, Poria be crushed to thumbnail size and get final product;
Dens Equi flower, Fructus Gardeniae, Thallus Laminariae (Thallus Eckloniae), Fructus Lycii are pulverized slightly and got final product;
Make the egg ointment: egg is boiled peel off shell and albumen, egg yolk is put in the iron pan done stir-fry with big fire.Egg yolk is fried to slightly being clamminess and oil is inclined to when fuel-displaced, continues to fry to fuel-displaced again, and oil is inclined to.Incline altogether and three oil and mix into the egg ointment.Frying black egg yolk slag discards;
(2) dipping:
With the Limonitum, Fructus Hordei Vulgaris, the Oryza glutinosa that crush, hold back in vain, Fructus Tribuli, Semen Abutili, the Radix Angelicae Dahuricae, Herba Portulacae, Bombyx Batryticatus, Fructus Ilicis Purpureae, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Radix Rhodiolae, Thallus Laminariae (Thallus Eckloniae), Rhizoma Cimicifugae, Fructus Gardeniae, Rhizoma Dioscoreae, Poria, Semen Benincasae, Fructus Lycii, Rhizoma Cyperi, Semen Armeniacae Amarum, Semen Persicae, Semen Cuscutae 24 flavor Chinese medicines mix in jar, adding concentration is 60% alcohol solution dipping, amount of alcohol added is submergence Chinese medicine and surpasses 1/5 of volume, amount to and soaked 120 hours, extracted a medicinal liquid in per 24 hours, and added 60% alcoholic solution after the extraction to original total amount; Extract medicinal liquid altogether five times; Flood the waste that finishes;
(3) filter:
With precipitating through 48 hours after the mixing of five extraction medicinal liquids, by filter square-bottomed bamboo basket, the various impurity of elimination;
(4) concentrate:
Filtered liquid medicine is poured in the round-bottomed flask that has condensation reflux unit, bottle is placed in the water-bath heats, reclaim the ethanol that steams, the Chinese medicine fluid extract after must concentrating in the flask by the water condensation reflux;
(5) system ointment:
The Chinese medicine fluid extract is heated to the white sucrose of crack back adding is stirred to dissolving; Adding each analog assistant then successively stirs.Again Borneolum Syntheticum is pulverized the back and is added and stir, add then the egg ointment stir medicine externally-applied ointment of the present invention.
CN96102894A 1996-04-16 1996-04-16 Medicine for treating scar, acne, brandy nose and pigmentation and its prepn. method Expired - Fee Related CN1054297C (en)

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Application Number Priority Date Filing Date Title
CN96102894A CN1054297C (en) 1996-04-16 1996-04-16 Medicine for treating scar, acne, brandy nose and pigmentation and its prepn. method

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CN1054297C CN1054297C (en) 2000-07-12

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101204507B (en) * 2007-12-13 2011-09-07 张益军 Tincture medicine for brandy nose
CN101874863B (en) * 2009-04-29 2011-09-21 朱洪河 External plaster for dispelling scar
CN101491653B (en) * 2008-01-23 2012-03-21 郑州大学 Traditional Chinese medicine composite for treating rosacea and use method thereof
CN103750459A (en) * 2014-01-16 2014-04-30 济南康众医药科技开发有限公司 Beverage for maintaining beauty and keeping young
CN103751342A (en) * 2014-02-14 2014-04-30 刘维忠 Medicine with functions of clearing away heat and toxic materials, diminishing swelling and relieving pain

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1035743C (en) * 1991-01-24 1997-09-03 周光明 Preparation method of scar-treating medicine

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101204507B (en) * 2007-12-13 2011-09-07 张益军 Tincture medicine for brandy nose
CN101491653B (en) * 2008-01-23 2012-03-21 郑州大学 Traditional Chinese medicine composite for treating rosacea and use method thereof
CN101874863B (en) * 2009-04-29 2011-09-21 朱洪河 External plaster for dispelling scar
CN103750459A (en) * 2014-01-16 2014-04-30 济南康众医药科技开发有限公司 Beverage for maintaining beauty and keeping young
CN103751342A (en) * 2014-02-14 2014-04-30 刘维忠 Medicine with functions of clearing away heat and toxic materials, diminishing swelling and relieving pain
CN103751342B (en) * 2014-02-14 2016-01-27 刘维忠 A kind of medicine with heat-clearing and toxic substances removing, reducing swelling and alleviating pain function

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