CN118286368A - Traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses as well as preparation method and application of decoction of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses as well as preparation method and application of decoction of traditional Chinese medicine composition Download PDFInfo
- Publication number
- CN118286368A CN118286368A CN202410286406.4A CN202410286406A CN118286368A CN 118286368 A CN118286368 A CN 118286368A CN 202410286406 A CN202410286406 A CN 202410286406A CN 118286368 A CN118286368 A CN 118286368A
- Authority
- CN
- China
- Prior art keywords
- parts
- resolving
- phlegm
- chinese medicine
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 101
- 206010062717 Increased upper airway secretion Diseases 0.000 title claims abstract description 98
- 208000026435 phlegm Diseases 0.000 title claims abstract description 98
- 239000000203 mixture Substances 0.000 title claims abstract description 52
- 239000008280 blood Substances 0.000 title claims abstract description 37
- 210000004369 blood Anatomy 0.000 title claims abstract description 36
- 230000003213 activating effect Effects 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 230000017531 blood circulation Effects 0.000 claims abstract description 33
- 230000001737 promoting effect Effects 0.000 claims abstract description 32
- 206010056342 Pulmonary mass Diseases 0.000 claims abstract description 29
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 26
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 26
- 235000008434 ginseng Nutrition 0.000 claims abstract description 26
- 244000248416 Fagopyrum cymosum Species 0.000 claims abstract description 22
- 241000237502 Ostreidae Species 0.000 claims abstract description 22
- 235000020636 oyster Nutrition 0.000 claims abstract description 22
- 241000270666 Testudines Species 0.000 claims abstract description 21
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 20
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 20
- 235000006463 Brassica alba Nutrition 0.000 claims abstract description 19
- 235000011371 Brassica hirta Nutrition 0.000 claims abstract description 19
- 235000017443 Hedysarum boreale Nutrition 0.000 claims abstract description 19
- 235000007858 Hedysarum occidentale Nutrition 0.000 claims abstract description 19
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 claims abstract description 19
- 244000140786 Brassica hirta Species 0.000 claims abstract description 18
- 241001547125 Fritillaria thunbergii Species 0.000 claims abstract description 6
- 241000050051 Chelone glabra Species 0.000 claims abstract 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000000706 filtrate Substances 0.000 claims description 15
- 241000935235 Fritillaria meleagris Species 0.000 claims description 14
- 244000161999 Acacia greggii Species 0.000 claims description 7
- 235000004608 catclaw acacia Nutrition 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- 241000220261 Sinapis Species 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 2
- 241000208340 Araliaceae Species 0.000 claims 4
- 239000012141 concentrate Substances 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 47
- 208000024891 symptom Diseases 0.000 abstract description 30
- 230000000694 effects Effects 0.000 abstract description 27
- 206010011224 Cough Diseases 0.000 abstract description 13
- 238000005728 strengthening Methods 0.000 abstract description 7
- 206010008479 Chest Pain Diseases 0.000 abstract description 4
- 238000011866 long-term treatment Methods 0.000 abstract description 2
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 240000004371 Panax ginseng Species 0.000 description 21
- 229940079593 drug Drugs 0.000 description 20
- 210000000952 spleen Anatomy 0.000 description 17
- 210000004072 lung Anatomy 0.000 description 14
- 210000002784 stomach Anatomy 0.000 description 13
- 210000004185 liver Anatomy 0.000 description 10
- 230000001717 pathogenic effect Effects 0.000 description 10
- 210000000038 chest Anatomy 0.000 description 9
- 235000012054 meals Nutrition 0.000 description 9
- 238000001914 filtration Methods 0.000 description 8
- 230000006872 improvement Effects 0.000 description 8
- 241000207929 Scutellaria Species 0.000 description 7
- 230000008451 emotion Effects 0.000 description 7
- 241000132012 Atractylodes Species 0.000 description 6
- 230000007812 deficiency Effects 0.000 description 6
- 235000013305 food Nutrition 0.000 description 6
- 201000007227 lymph node tuberculosis Diseases 0.000 description 6
- 230000000144 pharmacologic effect Effects 0.000 description 6
- 230000002685 pulmonary effect Effects 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 5
- 238000011156 evaluation Methods 0.000 description 5
- 230000008506 pathogenesis Effects 0.000 description 5
- 239000002994 raw material Substances 0.000 description 5
- 241000255789 Bombyx mori Species 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 206010033557 Palpitations Diseases 0.000 description 4
- 206010036790 Productive cough Diseases 0.000 description 4
- 208000033809 Suppuration Diseases 0.000 description 4
- 235000021270 cold food Nutrition 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000003203 everyday effect Effects 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 210000002216 heart Anatomy 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 235000021259 spicy food Nutrition 0.000 description 4
- 208000016255 tiredness Diseases 0.000 description 4
- 230000003867 tiredness Effects 0.000 description 4
- 241000173529 Aconitum napellus Species 0.000 description 3
- 244000037364 Cinnamomum aromaticum Species 0.000 description 3
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 description 3
- 240000009138 Curcuma zedoaria Species 0.000 description 3
- 235000003405 Curcuma zedoaria Nutrition 0.000 description 3
- 240000004534 Scutellaria baicalensis Species 0.000 description 3
- 235000017089 Scutellaria baicalensis Nutrition 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 244000273928 Zingiber officinale Species 0.000 description 3
- 235000006886 Zingiber officinale Nutrition 0.000 description 3
- 229940023019 aconite Drugs 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 239000001812 curcuma zedoaria berg. rosc. Substances 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 235000008397 ginger Nutrition 0.000 description 3
- 230000003211 malignant effect Effects 0.000 description 3
- 238000002203 pretreatment Methods 0.000 description 3
- 238000010926 purge Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 235000014347 soups Nutrition 0.000 description 3
- 235000019509 white turmeric Nutrition 0.000 description 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 244000144730 Amygdalus persica Species 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 241000596154 Belamcanda Species 0.000 description 2
- 241000202726 Bupleurum Species 0.000 description 2
- 241000131329 Carabidae Species 0.000 description 2
- 241000219051 Fagopyrum Species 0.000 description 2
- 235000009419 Fagopyrum esculentum Nutrition 0.000 description 2
- 241000766380 Iphigenia Species 0.000 description 2
- 241001673966 Magnolia officinalis Species 0.000 description 2
- 244000170916 Paeonia officinalis Species 0.000 description 2
- 235000006484 Paeonia officinalis Nutrition 0.000 description 2
- 235000006040 Prunus persica var persica Nutrition 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 241001116757 Pyrrosia lingua Species 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 235000019606 astringent taste Nutrition 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 210000000232 gallbladder Anatomy 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 201000003453 lung abscess Diseases 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000024121 nodulation Effects 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 230000002936 tranquilizing effect Effects 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 239000001169 1-methyl-4-propan-2-ylcyclohexa-1,4-diene Substances 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 244000178993 Brassica juncea Species 0.000 description 1
- 206010008469 Chest discomfort Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 240000006766 Cornus mas Species 0.000 description 1
- 244000163122 Curcuma domestica Species 0.000 description 1
- 235000003392 Curcuma domestica Nutrition 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010058314 Dysplasia Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000018779 Globus Sensation Diseases 0.000 description 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 241000264877 Hippospongia communis Species 0.000 description 1
- 208000006083 Hypokinesia Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 241000801118 Lepidium Species 0.000 description 1
- 206010024229 Leprosy Diseases 0.000 description 1
- 206010024642 Listless Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 240000005001 Paeonia suffruticosa Species 0.000 description 1
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 1
- 206010034686 Peritonsillar abscess Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 244000197580 Poria cocos Species 0.000 description 1
- 235000008599 Poria cocos Nutrition 0.000 description 1
- 208000037656 Respiratory Sounds Diseases 0.000 description 1
- 206010039424 Salivary hypersecretion Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010046996 Varicose vein Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047924 Wheezing Diseases 0.000 description 1
- 208000031975 Yang Deficiency Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 206010007625 cardiogenic shock Diseases 0.000 description 1
- 208000012839 conversion disease Diseases 0.000 description 1
- 235000003373 curcuma longa Nutrition 0.000 description 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 229960002179 ephedrine Drugs 0.000 description 1
- 210000004955 epithelial membrane Anatomy 0.000 description 1
- 230000005713 exacerbation Effects 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229940010454 licorice Drugs 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 208000017971 listlessness Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 150000007875 phellandrene derivatives Chemical class 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000002633 protecting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 235000013976 turmeric Nutrition 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine composition for resolving phlegm and promoting blood circulation and resolving masses, and a preparation method and application of decoction thereof, wherein the traditional Chinese medicine composition for resolving phlegm and promoting blood circulation and resolving masses comprises the following components in parts by weight: 10-30 parts of turtle shell, 10-30 parts of oyster, 1-5 parts of baical skullcap root, 1-10 parts of rhizoma pinellinae praeparata, 1-10 parts of ginseng, 1-10 parts of white mustard seed, 1-10 parts of fritillaria thunbergii, 1-10 parts of radix ranunculi ternati, 1-10 parts of spina gleditsiae, 1-10 parts of rhizoma curcumae, 1-10 parts of wild buckwheat rhizome and 1-10 parts of honey-fried licorice root. The traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses has good treatment effect, small side effect and higher safety, has the effects of resolving phlegm, activating blood, resolving masses, relieving symptoms, tonifying qi and strengthening body resistance, is mainly used for treating phlegm stagnation and lung nodules, can be used as a medicine for long-term treatment of lung nodules smaller than or equal to 8mm, can also be used for auxiliary treatment of lung nodules smaller than or equal to 8-30mm, and is suitable for and can relieve the symptoms of cough, phlegm, chest distress and debilitating phlegm stagnation and lung nodules of a patient.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses and a preparation method and application of decoction thereof.
Background
The incidence of lung nodules rises year by year, the pathogenesis of which is not clear, the treatment is very limited, and how to intervene in lung nodules has become a current hotspot and difficulty. Lung nodules can be caused by a variety of etiologies, such as dysplasia, infection, inflammation, old lesions, tumors, and the like. Western medicine often takes follow-up visit to lung nodules which do not reach the operation indication as the main part, treatment measures are limited, patients often cannot be effectively treated, and mental stress is high, so that malignant circulation is formed. At this time, the Chinese medicine can fully exert advantages, and can treat pulmonary nodules in a multi-target, multi-path and multi-link mode. The traditional Chinese medicine considers that the etiology and pathogenesis of the lung nodule are deficiency, phlegm, blood stasis and toxin, and the lung nodule is formed by mutually pulsating and obstructing qi movement. At present, the traditional Chinese medicine composition related to phlegm reduction is respectively disclosed in a traditional Chinese medicine composition for treating phlegm and blood stasis type pulmonary nodules, a preparation method and application thereof, and a traditional Chinese medicine composition for resolving masses, reducing phlegm and promoting blood circulation, a preparation method and application thereof, which are respectively disclosed in a traditional Chinese medicine composition for resolving masses, reducing phlegm and promoting blood circulation, which are respectively disclosed in a traditional Chinese medicine composition for treating phlegm and blood stasis type pulmonary nodules, but have the defects of more components and relatively poor curative effect.
Disclosure of Invention
In order to solve the technical problems, one of the purposes of the invention is to provide a Chinese medicinal composition which is used for strengthening body resistance and eliminating pathogenic factors in the whole formula, not only can improve the clinical curative effect of lung nodules, but also can maintain or reduce benign lung nodule size to a certain extent, and can treat phlegm-stasis and lung nodule with the functions of resolving phlegm, activating blood and resolving masses.
In order to achieve the above object, the technical scheme of the present invention is as follows: a traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses comprises the following components in parts by weight: 10-30 parts of turtle shell, 10-30 parts of oyster, 1-5 parts of baical skullcap root, 1-10 parts of rhizoma pinellinae praeparata, 1-10 parts of ginseng, 1-10 parts of white mustard seed, 1-10 parts of fritillaria thunbergii, 1-10 parts of radix ranunculi ternati, 1-10 parts of spina gleditsiae, 1-10 parts of rhizoma curcumae, 1-10 parts of wild buckwheat rhizome and 1-10 parts of honey-fried licorice root.
Preferably, the composition comprises the following components in parts by weight: 20 parts of turtle shell, 20 parts of oyster, 5 parts of baical skullcap root, 5-10 parts of rhizoma pinellinae praeparata, 5-10 parts of ginseng, 5-10 parts of white mustard seed, 5-10 parts of thunberg fritillary bulb, 5-10 parts of catclaw, 5-10 parts of spina gleditsiae, 5-10 parts of rhizoma zedoariae, 5-10 parts of wild buckwheat rhizome and 5 parts of honey-fried licorice root.
Further preferably, the composition comprises the following components in parts by weight: 20 parts of turtle shell, 20 parts of oyster, 5 parts of baical skullcap root, 5 parts or 10 parts of rhizoma pinellinae praeparata, 5 parts or 10 parts of ginseng, 5 parts or 10 parts of white mustard seed, 5 parts or 10 parts of thunberg fritillary bulb, 5 parts or 10 parts of radix ranunculi ternati, 5 parts or 10 parts of spina gleditsiae, 5 parts or 10 parts of rhizoma curcumae, 5 parts or 10 parts of wild buckwheat rhizome and 5 parts of honey-fried licorice root.
The second purpose of the invention is to provide a preparation method of the traditional Chinese medicine decoction for resolving phlegm, activating blood and resolving masses.
In order to achieve the above object, the technical scheme of the present invention is as follows: a preparation method of a traditional Chinese medicine decoction for resolving phlegm, promoting blood circulation and resolving masses comprises the steps of adding water into the traditional Chinese medicine composition for resolving phlegm, promoting blood circulation and resolving masses, decocting, filtering to obtain filtrate, and concentrating the filtrate to obtain the traditional Chinese medicine decoction for resolving phlegm, promoting blood circulation and resolving masses.
The specific decoction flow of the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses is as follows: decocting carapax Trionycis and Concha Ostreae in water for 20-40min, adding Scutellariae radix, rhizoma Pinelliae Preparata, ginseng radix, semen Sinapis Albae, bulbus Fritillariae Thunbergii, radix Ranunculi Ternati, spina Gleditsiae, curcumae rhizoma, rhizoma Fagopyri Dibotryis and radix Glycyrrhizae Preparata, and decocting for 20-40 min.
Wherein the filtrate is concentrated to 0.3-0.4g/mL according to the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses.
Wherein, the concentration mode is heated and concentrated.
The invention provides a traditional Chinese medicine decoction for resolving phlegm, activating blood and resolving masses, which is prepared by adopting the preparation method.
The invention aims at providing an application of the traditional Chinese medicine composition for resolving phlegm and promoting blood circulation and resolving masses or the traditional Chinese medicine decoction for resolving phlegm and promoting blood circulation and resolving masses in preparation of medicines for treating phlegm and blood stasis and lung nodule.
The invention has the beneficial effects that: the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses has good treatment effect, small side effect and higher safety, has the effects of resolving phlegm, activating blood, resolving masses, relieving symptoms, tonifying qi and strengthening body resistance, is mainly used for treating phlegm stagnation and lung nodules, can be used as a medicine for long-term treatment of lung nodules smaller than or equal to 8mm, can also be used for auxiliary treatment of lung nodules smaller than or equal to 8-30mm, and is suitable for and can relieve the symptoms of cough, phlegm, chest distress and debilitating phlegm stagnation and lung nodules of a patient.
Detailed Description
The principles and features of the present invention are described below in connection with the following examples, which are set forth to illustrate, but are not to be construed as limiting the scope of the invention. Advantages and features of the invention will become more apparent from the following description and from the claims.
The embodiment provides a traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses, which is characterized by comprising the following components in parts by weight: 10-30 parts of turtle shell (10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts or any range between two values), 10-30 parts of oyster (10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts or any range between two values, 1-5 parts (1 part, 2 parts, 3 parts, 4 parts or any range between two values), 1-10 parts of white atractylodes rhizome (1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 9 parts, 10 parts or any range between two values), 1-10 parts of white atractylodes rhizome (1 part, 2 parts, 3 parts, 4 parts or any range between two values), 1-10 parts of white atractylodes rhizome (1 part, 2 parts, 3 parts, 4 parts, 10 parts or any range between two values), 1 part of white atractylodes rhizome (1 part, 2 parts, 3 parts, 4 parts or 10 parts of white atractylodes rhizome (10 parts) and any range between two parts of radix scrophulariae (1 part, 2 parts of the range between 1 part, 2 parts of white ginseng) or 10 parts of any range between 1 part or 10 parts of any range between two values), 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts or a range corresponding to any two values), 1-10 parts of wild buckwheat (which can be any one of 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts or a range corresponding to any two values), 1-10 parts of zedoary (which can be any one of 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts or a range corresponding to any two values), 1-10 parts of wild buckwheat (which can be any one of 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts or a range corresponding to any two values), and 1-10 parts of licorice (which can be any one of 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 9 parts or 10 parts or a range corresponding to any two values).
Preferably, the composition comprises the following components in parts by weight: 20 parts of turtle shell, 20 parts of oyster, 5 parts of baical skullcap root, 5 parts or 10 parts of rhizoma pinellinae praeparata, 5 parts or 10 parts of ginseng, 5 parts or 10 parts of white mustard seed, 5 parts or 10 parts of thunberg fritillary bulb, 5 parts or 10 parts of radix ranunculi ternati, 5 parts or 10 parts of spina gleditsiae, 5 parts or 10 parts of rhizoma curcumae, 5 parts or 10 parts of wild buckwheat rhizome and 5 parts of honey-fried licorice root.
The embodiment also provides a preparation method of the decoction corresponding to the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses, which comprises the following specific preparation methods: decocting carapax Trionycis and Concha Ostreae in water for 20-40min (which can be any one of 20min、21min、22min、23min、24min、25min、26min、27min、28min、29min、30min、31min、32min、33min、34min、35min、36min、37min、38min、39min and 40min or the corresponding range between any two values), adding Scutellariae radix, rhizoma Pinelliae Preparata, ginseng radix, semen Sinapis Albae, bulbus Fritillariae Thunbergii, radix Ranunculi Ternati, spina Gleditsiae, curcumae rhizoma, rhizoma Fagopyri Dibotryis and radix Glycyrrhizae Preparata, decocting for 20-40min (which can be any one of 20min、21min、22min、23min、24min、25min、26min、27min、28min、29min、30min、31min、32min、33min、34min、35min、36min、37min、38min、39min and 40min or the corresponding range between any two values), filtering to obtain filtrate, and concentrating the filtrate under heating to obtain Chinese medicinal decoction with expectorant, blood circulation promoting and stagnation eliminating effects. Wherein the mass volume ratio of the phlegm-resolving, blood-activating and mass-resolving traditional Chinese medicine composition to water is at least 0.5g/mL (of course, the more water is not added, the better is, the more than 1.5g/mL is not needed, the range between any value or any two values of 0.5g/mL, 0.6g/mL, 0.7g/mL, 0.8g/mL, 0.9g/mL, 1g/mL, 1.1g/mL, 1.2g/mL, 1.3g/mL, 1.4g/mL and 1.5g/mL is not needed); wherein the filtrate is concentrated to 0.3-0.4g/mL (specifically, 0.3g/mL, 0.31g/mL, 0.32g/mL, 0.33g/mL, 0.34g/mL, 0.35g/mL, 0.36g/mL, 0.37g/mL, 0.38g/mL, 0.39g/mL and 0.4g/mL or the range between any two values) calculated by the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving hard mass, the added water amount of 100g of the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving hard mass is at least 500mL, at most 1500mL, and the concentrated liquid medicine after being boiled can be 300-400mL.
The mechanism analysis of the drug raw materials in this example:
turtle shell: salty and slightly cold. It enters liver and kidney meridians. [ Functions ] A Chinese medicinal composition with effects of nourishing yin, suppressing yang, softening and resolving hard mass, and relieving fever and steaming. Can be used for treating fever due to yin deficiency, fatigue heat, bone steaming, internal movement due to deficiency wind, amenorrhea, abdominal mass, and malaria.
Oyster: salty and slightly cold. It enters liver, gallbladder and kidney meridians. [ Functions ] the medicine has the functions of relieving the weight and tranquillizing, suppressing yang and tonifying yin, and softening and resolving hard mass. Can be used for treating palpitation, insomnia, dizziness, tinnitus, scrofula, phlegm nodule, and abdominal mass. Calcined oyster has the effect of astringing and inducing astringency. Can be used for treating spontaneous perspiration, night sweat, spermatorrhea, leukorrhagia, and gastralgia.
Radix Scutellariae Baicalensis: bitter and cold. It enters lung, gallbladder, spleen, large intestine and small intestine meridians. [ functional indications ] clear heat and dry dampness, purge fire and detoxify, stop bleeding, and prevent abortion. Can be used for treating damp-heat, summer-heat, chest distress, emesis, and malignant boil, damp-heat distention and fullness, dysentery, jaundice, cough due to lung heat, polydipsia due to high fever, hematemesis, carbuncle, skin sore, and fetal movement.
Rhizoma Pinelliae Preparata: pungent and warm. Enter spleen, stomach and lung meridians. [ functional indications ] dampness-eliminating and phlegm-resolving functions. Can be used for treating cough and asthma with excessive phlegm, phlegm retention, palpitation, dizziness, and headache.
Ginseng: sweet, slightly bitter and flat. It enters spleen, lung and heart meridians. [ FUNCTIONS ] is effective in invigorating primordial qi, recovering pulse, relieving depletion, invigorating spleen, benefiting lung, promoting salivation, and tranquilizing mind. Can be used for treating asthenia, cold limbs, weak pulse, spleen deficiency, anorexia, lung deficiency, cough, body fluid consumption, thirst, internal heat, chronic diseases, deficiency, palpitation, insomnia, sexual impotence, and cold womb; heart failure, cardiogenic shock.
White mustard seed: octyl; temperature. Lung, liver, spleen, stomach, pericardium meridian. [ functional indications ] phlegm-resolving and fluid-expelling means; resolving hard mass and detumescence; cough and dyspnea with excessive phlegm, chest fullness and hypochondrium pain, numbness of limbs, joint pain, damp-phlegm flow, carbuncle and swelling.
Thunberg fritillary bulb: bitter and cold. Enter lung and heart meridians. [ functional indications ] clear heat and dissipate nodulation, resolve phlegm and relieve cough, and can be used for treating wind-heat invading lung, phlegm-fire cough, pulmonary abscess, acute mastitis, scrofula and sore toxin.
Radix Ranunculi Ternati: sweet, pungent and warm. It enters liver and lung meridians. [ Functions ] the medicine can dissipate nodulation and reduce swelling. Can be used for treating scrofula without ulcer and tuberculous lymphadenitis.
Spina gleditsiae: pungent and warm in nature. Enter liver and stomach meridians. [ Functions ] can be used for treating early stage of carbuncle or suppuration without ulcer; it is indicated for scabies and leprosy.
Zedoary turmeric: pungent and bitter, warm. Enter liver and spleen meridians. [ functional indications ] move qi, break blood, remove food retention and relieve pain. Is used for burning lump, blood stasis amenorrhea, food stagnation and distending pain.
Wild buckwheat rhizome: slightly pungent and astringent, cool. Enter lung meridian. [ Functions ] clear away heat and toxic materials, expel pus and remove blood stasis. Can be used for treating lung abscess, measles pneumonia, and peritonsillar abscess.
Honey-fried licorice root: sweet and flat. It enters heart, lung, spleen and stomach meridians. [ Functions ] the medicine can tonify spleen and stomach, tonify qi and recover pulse. Can be used for treating weakness of spleen and stomach, listlessness, debilitation, palpitation, and pulse knot.
In the formula of the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses, which is provided in the embodiment, the turtle shell and oyster are used for softening hardness and resolving masses, and dredging collaterals and removing arthralgia; spina gleditsiae and radix ranunculi ternati assist turtle shell and oyster to play the roles of softening hardness, resolving hard mass and reducing phlegm; zedoary can break blood and remove stasis, and dredge channels and collaterals; rhizoma Pinelliae Preparata, semen Sinapis Albae, bulbus Fritillariae Thunbergii, and rhizoma Pinelliae Preparata, and eliminating phlegm and dampness; wild buckwheat rhizome has the effects of clearing lung-heat, expelling pus and removing blood stasis; radix Scutellariae has effects of clearing heat, eliminating dampness, purging pathogenic fire and removing toxic substances; ginseng has the effects of supplementing qi and strengthening body resistance; radix Glycyrrhizae Preparata regulates the drugs.
Clinical report:
Data and method
1. General data:
120 cases of phlegm-blood stasis interengaged pulmonary nodule patients, benign pulmonary nodules less than or equal to 8mm, are randomly divided into 4 groups of 30 people each, and are clinically studied for 3 months.
2. Clinical study method:
The four components are a control group, a treatment group 1, a treatment group 2 and a treatment group 3, wherein the treatment group 1, the treatment group 2 and the treatment group 3 take decoction of the composition for resolving phlegm, activating blood and resolving masses orally three times a day, the dosage of each decoction is 100mL, and the control group is selected as the general basic treatment of the non-interfered benign lung nodule. The treatment periods of the control group, the treatment group 1, the treatment group 2 and the treatment group 3 are all three months, and the treatment period is over, and the symptoms are scored and the chest CT is subjected to flat scanning examination.
The treatment group 1 decoction and the treatment mode are as follows: putting 20g of turtle shell and 20g of oyster into a decoction pot, adding 1100mL of water for decoction, timing for 30min after boiling, then adding 5g of radix scutellariae, 10g of rhizoma pinellinae praeparata, 5g of ginseng, 10g of white mustard seed, 10g of fritillary bulb, 10g of radix ranunculi ternati, 5g of spina gleditsiae, 5g of rhizoma curcumae, 10g of wild buckwheat rhizome and 5g of honey-fried licorice root, continuously decocting for 30min, and filtering to obtain 300mL of filtrate. The medicine is taken after three times of meals, namely, early, middle and late every day, 100mL of the medicine is taken every time, and people are prohibited to eat spicy and cold food, avoid wind cold, regulate emotion and care living.
The treatment group 2 decoction and the treatment mode are as follows: putting 20g of turtle shell and 20g of oyster into a decoction pot, adding 1050mL of water for decoction, timing for 30min after boiling, and then adding 5g of radix scutellariae, 5g of rhizoma pinellinae praeparata, 5 parts of ginseng, 5g of white mustard seed, 5g of fritillary bulb, 5g of radix ranunculi ternati, 10g of spina gleditsiae, 10g of rhizoma curcumae, 5g of wild buckwheat rhizome and 5g of honey-fried licorice root. Continuously decocting for 30min, and filtering to obtain 300mL of filtrate; the medicine is taken after three times of meals, namely, early, middle and late every day, 100mL of the medicine is taken every time, and people are prohibited to eat spicy and cold food, avoid wind cold, regulate emotion and care living.
The treatment group 3 decoction and the treatment mode are as follows: putting 20g of turtle shell and 20g of oyster into a decoction pot, adding 1000mL of water for decoction, timing for 30min after boiling, and then adding 5g of radix scutellariae, 5g of rhizoma pinellinae praeparata, 10g of ginseng, 5g of white mustard seed, 5g of fritillary bulb, 5g of radix ranunculi ternati, 5g of spina gleditsiae, 5g of rhizoma curcumae, 5g of wild buckwheat rhizome and 5g of honey-fried licorice root. Continuously decocting for 30min, and filtering to obtain 300mL filtrate. The medicine is taken after three times of meals, namely, early, middle and late every day, 100mL of the medicine is taken every time, and people are prohibited to eat spicy and cold food, avoid wind cold, regulate emotion and care living.
The general basic treatments for the control group were mainly: patients in the control group do not need any intervention measures, and patients are instructed to avoid eating spicy and cold food, avoid wind cold, regulate emotion and care for living.
3. The test results are as follows:
The results of the symptom scores are shown in table 1:
table 1 shows the lung nodule effectiveness of the control and treatment groups
| Group of | Clinical effective rate (%) |
| Control group | 78.53 |
| Treatment group 1 | 91.45 |
| Treatment group 2 | 94.12 |
| Treatment group 3 | 96.78 |
Wherein, the evaluation criterion is effectively evaluated
1) After 3 months, the focus on the same position of the chest CT is rechecked to disappear;
2) And 3 months later, the focus on the same position of the chest CT is reduced by more than or equal to 1mm compared with the front focus.
3) After 3 months, the focus of the chest CT at the same position is unchanged, but the patient has corresponding symptom improvement (the judgment standard of symptom improvement only annotates).
Invalid evaluation criterion
1) And 3 months later, the focus increase of the breast CT at the same position is more than or equal to 1mm.
2) After 3 months, the focus at the same position of the chest CT is stable or the focus is reduced by more than or equal to 1mm, but the symptoms of lobation, burr or pleural dishing appear.
Note that: evaluation of symptom improvement degree (efficacy and effectiveness are regarded as symptom improvement):
The efficacy index n= (pre-treatment integral-post-treatment integral)/pre-treatment integral x 100%, wherein the integral is divided into 100 points, the pre-treatment integral and post-treatment integral being scored by the attending physician.
The effect is shown: the symptoms are basically or completely disappeared, or n is more than or equal to 70%;
the method is effective: the symptoms are improved, and n is more than or equal to 30 percent;
no improvement: no obvious improvement of symptoms, n <30%;
exacerbation of symptoms: symptoms are aggravated with n <0.
The chest CT plain scan results are shown in table 2:
table 2 shows the results of CT flat scan examination of the chest of the control and treatment groups
The results show that: compared with the control group, the treatment group not only can improve the clinical curative effect of the lung nodule, but also can maintain or reduce the size of benign lung nodule to a certain extent, and is mainly used for treating phlegm stagnation lung nodule.
In this example, the medicines used in the treatment groups are the same, but the dosages of the medicines are different, in the treatment group 1, the dosage of the medicines is larger, the five medicines mainly comprise rhizoma pinellinae praeparata, semen brassicae, thunberg fritillary bulb, radix ranunculi ternati and rhizoma fagopyri Dibotryis, the five medicines have the effects of eliminating phlegm and resolving masses, relieving stuffiness and dispersing masses, and lowering adverse qi and relieving vomiting, and are used for treating symptoms such as excessive phlegm cough, gomphosis scrofula, sore pain, globus hystericus, upward adverse rising of stomach qi, nausea and vomiting, chest stuffiness and chest stuffiness, tubers contain volatile oil, a small amount of fat, various amino acids, ephedrine, trigemine and alkaloids with similar pharmacological effects as that of the phellandrene, and pharmacological experiments show that the diluted alcohol or water extract of the rhizoma pinellinae praeparata has obvious inhibiting effect on experimental tumors of animals. The "Chinese herbal meaning" mentions "white mustard seed, which has the effects of resolving phlegm and removing distention and fullness, and is extremely fast, and has a thick taste and light smell, so that the Chinese herb can be guided quickly, but does not consume very much qi, and can remove phlegm of the hypochondrium and the epithelial membrane, so that people near the heart can be known. As proved by modern pharmacological researches, the fritillaria thunbergii not only has the functions of resolving phlegm and resolving masses, but also has the lung protecting effect, and is used for treating lung diseases. The radix ranunculi ternati is pungent in flavor and good in promoting the circulation of qi, and has obvious efficacy of dissipating phlegm-fluid retention and stagnation in the body. Pharmacological studies show that the radix ranunculi ternati has the functions of resisting bacteria, viruses and tumors and enhancing the immunity of organisms. The golden buckwheat rhizome has the effects of clearing heat and detoxicating, removing blood stasis and expelling pus, and pharmacological research shows that the active ingredients of the golden buckwheat rhizome can inhibit bacteria, resist cancer and enhance immunity. The dosage of spina gleditsiae and rhizoma curcumae in the treatment group 2 is large, so that the blood activating curative effect of the formula is enhanced. The dosage of the ginseng in the treatment group 3 is larger, the dosage of the pathogenic factor attacking medicine is relatively reduced compared with that of the treatment group 1 and the treatment group 2, the dosage of the pathogenic factor attacking medicine is greater than that of the treatment group 1 and the treatment group 2, the qi is necessary to be deficient, the dosage of the ginseng is increased, and the pathogenic factor attacking medicine can strengthen the effects of resolving phlegm, resolving masses, promoting blood circulation and the like so as to achieve the effect of eliminating pathogenic factors, but the pathogenic factor attacking medicine is inevitably harmful to the body.
Case 1
The embodiment provides a traditional Chinese medicine composition of phlegm-resolving, blood-activating and stagnation-resolving soup, which comprises the following raw materials in parts by mass: 20g of turtle shell, 20g of oyster, 5g of baical skullcap root, 10g of rhizoma pinellinae praeparata, 5g of ginseng, 10g of white mustard seed, 10g of fritillaria thunbergii, 10g of radix ranunculi ternati, 5g of spina gleditsiae, 5g of rhizoma curcumae, 10g of wild buckwheat rhizome and 5g of honey-fried licorice root.
Patient 1, female, age 26, had symptoms of cough, expectoration, debilitation, tiredness, pale tongue, watery, yellow and greasy coating, slippery pulse. The diagnosis is performed. For resolving phlegm and promoting blood circulation, resolving masses and relieving symptoms, tonifying qi and strengthening body resistance (preferably resolving phlegm), the traditional Chinese medicine composition of the embodiment 1 is selected, firstly, the turtle shell and oyster are placed in a decoction pot, 1000mL of water is added for decoction for 30min, then the baikal skullcap root, the rhizoma pinellinae praeparata, the ginseng, the white mustard seed, the thunberg fritillary bulb, the catclaw, the spina gleditsiae, the rhizoma zedoariae, the wild buckwheat and the honey-fried licorice root are added for continuous decoction for 30min, filtering is carried out, and the filtrate is concentrated to 300mL, so that the decoction of the traditional Chinese medicine composition for resolving masses, resolving phlegm and promoting blood circulation is obtained, and is taken orally after three meals of 100mL each time after meals, and is forbidden to eat spicy, cool food, avoid wind cold, regulate emotion and take with cautions. After one treatment course (one treatment course is one month), the symptoms are improved (the evaluation criteria of the improvement of the symptoms are related comments on the evaluation of the improvement degree of the symptoms).
Case 2
The embodiment provides a traditional Chinese medicine composition of phlegm-resolving, blood-activating and stagnation-resolving soup, which comprises the following raw materials in parts by mass: the raw materials in parts by weight are as follows: 20g of turtle shell, 20g of oyster, 5g of baical skullcap root, 5g of rhizoma pinellinae praeparata, 5g of ginseng, 5g of white mustard seed, 5g of fritillaria thunbergii, 5g of catclaw, 10g of spina gleditsiae, 10g of rhizoma curcumae, 5g of wild buckwheat rhizome and 5g of honey-fried licorice root.
Patient 2, female, age 56, has symptoms of cough, expectoration, chest distress, tiredness, dark tongue with ecchymosis, tongue bottom, varicose vein, yellow and greasy coating, and wiry pulse. The diagnosis is performed. For resolving phlegm and promoting blood circulation, resolving masses and relieving symptoms, tonifying qi and strengthening body resistance (preferably promoting blood circulation), the traditional Chinese medicine composition of the embodiment 2 is selected, firstly, the turtle shell and oyster are placed in a decoction pot, 1000mL of water is added for decoction for 30min, then the baikal skullcap root, the rhizoma pinellinae praeparata, the ginseng, the white mustard seed, the thunberg fritillary bulb, the catclaw, the spina gleditsiae, the rhizoma zedoariae, the wild buckwheat and the honey-fried licorice root are added for continuous decoction for 30min, filtering is carried out, and the filtrate is concentrated to 300mL, so that the decoction of the traditional Chinese medicine composition for resolving masses, resolving phlegm and promoting blood circulation is obtained, and is taken orally after three meals of 100mL each time after meals, and is forbidden to eat spicy, cool food, avoid wind cold, regulate emotion and take with cautions. After one treatment course, the symptoms are improved.
Case 3
The embodiment provides a traditional Chinese medicine composition of phlegm-resolving, blood-activating and stagnation-resolving soup, which comprises the following raw materials in parts by mass:
20g of turtle shell, 20g of oyster, 5g of baical skullcap root, 5g of rhizoma pinellinae praeparata, 10g of ginseng, 5g of white mustard seed, 5g of fritillary bulb, 5g of catclaw, 5g of spina gleditsiae, 5g of rhizoma curcumae, 5g of wild buckwheat rhizome and 5g of honey-fried licorice root.
Patient 3, men, age 48, had symptoms of cough, expectoration, wheezing, debilitation, tiredness, pale tongue with white and greasy coating, and deep and thready pulse. The diagnosis is performed. For treating phlegm and blood circulation, eliminating stagnation and relieving symptoms, tonifying qi and strengthening body resistance (preference to tonifying qi), the traditional Chinese medicine composition for resolving phlegm and blood circulation and eliminating stagnation of the embodiment 3 is selected, firstly, the turtle shell and oyster are placed in a decoction pot, 1000mL of water is added for decoction for 30min, then the baikal skullcap root, rhizoma pinellinae praeparata, ginseng, white mustard seed, thunberg fritillary bulb, catclaw, spina gleditsiae, rhizoma zedoariae, wild buckwheat and honey-fried licorice root are added for continuous decoction for 30min, filtering is carried out, the filtrate is concentrated to 300mL, and the decoction of the traditional Chinese medicine composition for resolving stagnation, resolving phlegm and promoting blood circulation is obtained, and is taken orally after three meals of early, middle and late meals every day, 100mL of foods which are pungent, cold and cool are forbidden during taking, wind cold is avoided, emotion is regulated, and living with cautions. After one treatment course, the symptoms are improved.
The decoction (phlegm-resolving, blood-activating and stagnation-resolving decoction) prepared from the traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses provided by the embodiment not only can effectively improve the clinical curative effect of lung nodules, but also can maintain or reduce the size of benign lung nodules to a certain extent, can effectively relieve common symptoms such as cough, expectoration, hypodynamia, tiredness and the like caused by benign lung nodules, can improve the life quality of patients, and has small side effect and higher safety.
The present example has reduced ingredients including bupleurum, blackberry lily, stiff silkworm, ginger, prepared aconite, red paeony root, cassia twig, pepperweed seed, pyrrosia lingua, moutan bark, dogwood, ground beetle, honeycomb, peach kernel, indian iphigenia bulb and magnolia bark compared with the traditional Chinese medicine composition for treating phlegm and blood stasis interengaged lung nodule, the preparation method and the application of the traditional Chinese medicine composition for treating phlegm and blood stasis intered lung nodule of the traditional Chinese medicine of the patent document 1 (CN 115381914A) and the traditional Chinese medicine composition of the traditional Chinese medicine of the patent document 2 (CN 114699502B). Wherein, peach kernel, ground beetle, red paeony root and tree peony bark break blood and remove stasis and dredge channels and collaterals, while the invention retains rhizoma zedoariae to promote blood circulation and remove stasis; the modern pharmacological research of the Indian iphigenia bulb can resist tumors, but has pungent and cold flavor, so as to clear heat and detoxify, detumescence and resolving masses, and is mainly used for treating carbuncles, malignant sores, scrofula tuberculosis, sore throat and the like. The phlegm-resolving and stasis-resolving medicines, the blood-activating and stasis-resolving medicines and the heat-clearing and detoxifying medicines are all evil-dispelling medicines, the strengthening-body-resistance medicines are only ginseng, and one of the compatibility modes of the proportion of the combination of the pathogenesis of patients can easily consume the vital qi of the human body, and the theory of evaluating heat from questions of Su: the pathogenic qi is deficient, which emphasizes the dominant position of the healthy qi in the pathogenesis, so the embodiment adds the honey-fried licorice root to strengthen healthy qi and harmonize the medicines; the spleen and stomach are damaged, spleen governs transportation and transformation, and the medicines are required to be transported and transformed by the spleen and stomach like food grains, most of the medicines are cold and cool in nature, are easy to obstruct spleen and stomach qi movement, influence middle energizer and the function of mediating phlegm dampness to grow internally, and the medicines of semen lepidii, pyrrosia lingua and blackberry lily bitter and cold are removed in the same way, and only wild buckwheat and radix scutellariae are used for clearing lung and purging fire, and detoxifying and drying dampness; although the hive and the stiff silkworm can permeate the hive and directly reach the disease sites, the hive and the stiff silkworm both belong to pathogenic factor removing medicines, and the worm medicines have strong pathogenic factor removing power, and consider the disease condition of insufficient background of the patients, so the hive and the stiff silkworm are not used; the baked ginger flavor Xin Xingre and the prepared aconite root large Xin Dare are used for treating symptoms such as abdominal pain, diarrhea and the like caused by deficiency-cold of spleen and stomach, cassia twig is used for warming yang and qi, warming channel and promoting blood circulation, and has the meaning of 'disease phlegm and fluid retention', but the treatment principle is considered, so that the baked ginger flavor Xin Xingre and the prepared aconite root large Xin Dare are mainly suitable for phlegm and fluid retention caused by spleen yang deficiency, and have better effect when being matched with medicines such as poria cocos, bighead atractylodes rhizome and the like, but the pathogenesis of the baked cassia twig is not suitable for patients with pulmonary nodules; fructus Corni is mainly used for tonifying liver and kidney, astringing and inducing astringency, and is not used because patients with liver and kidney deficiency rarely take fructus Corni and the fructus Corni is greasy and obstructed the stomach; the magnolia officinalis has the effects of eliminating dampness and resolving phlegm, descending qi and removing fullness, mainly enters spleen and stomach channels, mainly treats dyspepsia and abdominal distention, and the bupleurum root can regulate a pivot machine, but is easy to rob liver yin, and the treatment period of the disease is long, and should be combined with liver softening products, but the embodiment aims at ensuring less medicine and special efficacy, is anti-dispersion medicine efficacy, is omitted, and has good curative effect through long-term clinical observation.
The above description is only of the preferred embodiments of the present invention, and is not intended to limit the present invention in any way; those skilled in the art will readily appreciate that the present invention is well adapted to carry out the ends of the same out as described herein; however, those skilled in the art will appreciate that many modifications, adaptations, and variations of the present invention are possible in light of the above teachings, without departing from the scope of the invention; meanwhile, any equivalent changes, modifications and evolution of the above embodiments according to the essential technology of the present invention still fall within the scope of the present invention.
Claims (10)
1. The traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses is characterized by comprising the following components in parts by weight: 10-30 parts of turtle shell, 10-30 parts of oyster, 1-5 parts of baical skullcap root, 1-10 parts of rhizoma pinellinae praeparata, 1-10 parts of ginseng, 1-10 parts of white mustard seed, 1-10 parts of fritillaria thunbergii, 1-10 parts of radix ranunculi ternati, 1-10 parts of spina gleditsiae, 1-10 parts of rhizoma curcumae, 1-10 parts of wild buckwheat rhizome and 1-10 parts of honey-fried licorice root.
2. The traditional Chinese medicine composition for resolving phlegm, promoting blood circulation and resolving masses according to claim 1 is characterized by comprising the following components in parts by weight: 20 parts of turtle shell, 20 parts of oyster, 5 parts of baical skullcap root, 5-10 parts of rhizoma pinellinae praeparata, 5-10 parts of ginseng, 5-10 parts of white mustard seed, 5-10 parts of thunberg fritillary bulb, 5-10 parts of catclaw, 5-10 parts of spina gleditsiae, 5-10 parts of rhizoma zedoariae, 5-10 parts of wild buckwheat rhizome and 5 parts of honey-fried licorice root.
3. The traditional Chinese medicine composition for resolving phlegm, promoting blood circulation and resolving masses according to claim 2 is characterized by comprising the following components in parts by weight: 20 parts of turtle shell, 20 parts of oyster, 5 parts of baical skullcap root, 5 parts or 10 parts of rhizoma pinellinae praeparata, 5 parts or 10 parts of ginseng, 5 parts or 10 parts of white mustard seed, 5 parts or 10 parts of thunberg fritillary bulb, 5 parts or 10 parts of radix ranunculi ternati, 5 parts or 10 parts of spina gleditsiae, 5 parts or 10 parts of rhizoma curcumae, 5 parts or 10 parts of wild buckwheat rhizome and 5 parts of honey-fried licorice root.
4. A preparation method of a traditional Chinese medicine decoction for resolving phlegm, promoting blood circulation and resolving masses, which is characterized in that the preparation method is to add water into the traditional Chinese medicine composition for resolving phlegm, promoting blood circulation and resolving masses according to any one of claims 1-3, filter the obtained filtrate, and concentrate the filtrate to obtain the traditional Chinese medicine decoction for resolving phlegm, promoting blood circulation and resolving masses.
5. The preparation method of the traditional Chinese medicine decoction for resolving phlegm, promoting blood circulation and resolving masses, which is characterized in that the specific decoction flow of the traditional Chinese medicine composition for resolving phlegm, promoting blood circulation and resolving masses is as follows: decocting carapax Trionycis and Concha Ostreae in water for 20-40min, adding Scutellariae radix, rhizoma Pinelliae Preparata, ginseng radix, semen Sinapis Albae, bulbus Fritillariae Thunbergii, radix Ranunculi Ternati, spina Gleditsiae, curcumae rhizoma, rhizoma Fagopyri Dibotryis and radix Glycyrrhizae Preparata, and decocting for 20-40 min.
6. The method for preparing the traditional Chinese medicine decoction for resolving phlegm, promoting blood circulation and resolving masses according to claim 4, wherein the mass-volume ratio of the traditional Chinese medicine composition for resolving phlegm, promoting blood circulation and resolving masses to water is at least 0.5g/mL.
7. The method for preparing the phlegm-resolving, blood-activating and stagnation-resolving traditional Chinese medicine decoction according to claim 4, wherein the filtrate is concentrated to 0.3-0.4g/mL according to the traditional Chinese medicine composition for resolving phlegm, blood-activating and stagnation-resolving.
8. The method for preparing the traditional Chinese medicine decoction for resolving phlegm, promoting blood circulation and resolving masses according to claim 4, wherein the concentration mode is heating and concentrating.
9. A traditional Chinese medicine decoction for resolving phlegm, activating blood and resolving masses, which is characterized by being prepared by the preparation method according to any one of claims 4-8.
10. Use of a Chinese medicinal composition for resolving phlegm, promoting blood circulation, and resolving masses according to any one of claims 1-4 or a Chinese medicinal decoction for resolving phlegm, promoting blood circulation, and resolving masses according to claim 9 in the preparation of a medicament for treating phlegm stagnation and lung nodule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410286406.4A CN118286368A (en) | 2024-03-13 | 2024-03-13 | Traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses as well as preparation method and application of decoction of traditional Chinese medicine composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410286406.4A CN118286368A (en) | 2024-03-13 | 2024-03-13 | Traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses as well as preparation method and application of decoction of traditional Chinese medicine composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN118286368A true CN118286368A (en) | 2024-07-05 |
Family
ID=91681868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202410286406.4A Pending CN118286368A (en) | 2024-03-13 | 2024-03-13 | Traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses as well as preparation method and application of decoction of traditional Chinese medicine composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN118286368A (en) |
-
2024
- 2024-03-13 CN CN202410286406.4A patent/CN118286368A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102048933B (en) | Chinese medicinal composition for treating infantile diarrhea and preparation method thereof | |
| CN104208245B (en) | Tinea manus and pedis Traditional Chinese medicine medicated bath and preparation method | |
| CN114699502B (en) | Traditional Chinese medicine composition for resolving masses, reducing phlegm and activating blood circulation, preparation method and application | |
| CN102772781A (en) | Traditional Chinese medicine preparation for treating chronic colitis and preparation method thereof | |
| CN104189789A (en) | Traditional Chinese medicine composition for treating acute infectious jaundice type hepatitis | |
| CN104001045A (en) | Drug for treating dog pneumonia and preparation method thereof | |
| CN105284727A (en) | Broiler chicken breeding method | |
| CN104873926A (en) | Traditional Chinese medicine preparation for treating diarrhea as well as preparation method and application of traditional Chinese medicine preparation | |
| CN112717113B (en) | Traditional Chinese medicine composition for treating allergic rhinitis and paste formula and application thereof | |
| CN113876872A (en) | Formula for treating reflux esophagitis | |
| CN118286368A (en) | Traditional Chinese medicine composition for resolving phlegm, activating blood and resolving masses as well as preparation method and application of decoction of traditional Chinese medicine composition | |
| CN103055218A (en) | Traditional Chinese medicine composition for treating neonatal jaundice and preparation method thereof | |
| CN106334114A (en) | Traditional Chinese medicine for treating pharyngitis and preparation method thereof | |
| CN103099885A (en) | Soft capsules having acne removing function and preparation method thereof | |
| CN111760006A (en) | Medicine formula for treating liver cirrhosis | |
| CN105146652A (en) | Beverage for treating oral ulcer | |
| CN105233078A (en) | Traditional Chinese medicine composition for treating viral hepatitis | |
| CN104888178A (en) | Infantile diarrhea treatment traditional Chinese medicine | |
| CN103830713B (en) | Be used for the treatment of medicine of chicken wind-cold type cough and preparation method thereof | |
| CN103623192B (en) | Medicine being used for the treatment of pig blue-ear disease and preparation method thereof | |
| CN103007145A (en) | Traditional Chinese medicine composition for treating children rotavirus enteritis and preparation method of composition | |
| CN107638557A (en) | A kind of medicine for treating the infection of the upper respiratory tract and preparation method thereof | |
| CN106334155A (en) | Traditional Chinese medicine composition for treating arterial thyromegaly and preparation method thereof | |
| CN108721540A (en) | Treat the Chinese medicine preparation of six kinds of situations of liver cancer | |
| CN107582791A (en) | A kind of medicine for treating amenorrhoea and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |