CN1182537A - Plant protective agent and preparing method thereof - Google Patents

Abstract

A kind of protective agent for plant is composed of medicinal liquid which is extracted from flavescent sophora root, tobacco, tuber of stemona, bark of cork tree, root of large-flowered skullcap, rhizome of Chinese goldthread and isatis root, and edible alcohol, turpentine, skin-penetrating agent, 4017 emulgent and stabilizer. The characterisitic of said protective agent is as follows: multifunction of insecticidal and bactericidal, preventing and curing desease, increasing the folar fertilizer and improving the soil, besides it features also toxicless and pollution free.

Description

A kind of plant protection product and preparation method thereof

The present invention relates to a kind of plant protection product, be used for multiple kinds of crops, forest, vegetable or flower desinsection, sterilization, diseases prevention, cure the disease, increase foliage fertilizer and improve the soil.

Agricultural goes up the agricultural chemicals that uses at present, the complex preparation that chemical pesticide or chemical pesticide are arranged, though chemical pesticide good disinsection effect, but long-term the use is because it is a monospecific antibody, so often develop immunity to drugs and farming chronic poisoning already, cause the underproduction of agricultural in poor harvest, while is contaminated environment also, destroys the ecological balance, though some agricultural chemicals is to people and animals' low toxicity, low-residual, but be seeped into and make soil compaction in the soil, the injury plant root also has a kind of plant pesticide, and it is mainly with the Wormseed element, stemonine is a primary raw material, its weak point is that drug effect is not fairly obvious, and raw material is limited, the cost height.Some agricultural chemicals since the property of medicine bad, spray the back useful effect little, can not give full play to pharmaceutical efficacy.

Purpose of the present invention is the shortcoming and deficiency in order to overcome above-mentioned prior art just, and a kind of Chinese medicine with strong bactericidal and Insecticidal effect is provided, and the soup through extracting is to the plant protection product of plant protection, and the present invention simultaneously also provides this protectant preparation method.

The objective of the invention is to be achieved through the following technical solutions:

A kind of plant protection product is characterized in that it is made up of the raw material of following weight ratio, and each component consumption proportion (by weight) is:

The yellow Siberian cocklebur 10-20 of kuh-seng 30-50 part tobacco 30-50 part tuber of stemona 2-6 part golden cypress 10-20 part part

Coptis 2-7 part isatis root 5-15 part turpentine oil 5-15 part edible alcohol 5-15 part

Transdermal agent 5-15 part 4017 emulsifier 5-15 part stabilizing agent 5-8 parts.

The preparation method of plant protection product is characterized in that it is undertaken by the following step:

A) selected kuh-seng, tobacco, the tuber of stemona, golden cypress, Huang Ling, the coptis, each Chinese medicine of isatis root;

B) with the kuh-seng 30-50 weight portion of (a), tobacco 30-50 weight portion, tuber of stemona 2-6 weight portion, golden cypress 10-20 weight portion, yellow Siberian cocklebur 10-20 weight portion, coptis 2-7 weight portion, isatis root 5-15 weight portion, respectively through washing, fragmentation or section add the heavy 6-9 of medicine water doubly respectively and decoct 3-4 hour extraction soup in extractors, and separate various soups in various medicines, its dregs of a decoction add the heavy 5-8 of medicine water doubly again and carry out secondary decoction 2-3 hour, and the soup of separation merges with a soup and mixes;

C) the various admixing medical solutions with (b) filter respectively, vacuum concentration, the Baume degrees that makes soup is squeezed in the edible alcohol jar with pump then and is carried out " wine is heavy " at 10-12, makes when containing edible alcohol 5-15 weight portion in the soup and separates, and obtains intermediate products;

D) in intermediate products, add turpentine oil 5-15 weight portion and transdermal agent 5-15 weight portion, 4017 emulsifier 5-15 weight portions, stabilizing agent 5-8 weight portion fully mixes the back filling bottle;

E) test vanning, warehouse-in.

The Chinese medicine that protection liquid of the present invention adopts all has desinsection, sterilizing function; extract hundreds of antibody and various nutrients by decocting; adopt edible alcohol can make that macromolecular substances precipitates in the soup; guarantee that soup meets national standard; add turpentine oil except that emulsification, also have synergistic effect, transdermal agent can play osmosis; improve drug effect and make plant leaf blade fully absorb nutrition.

Protectant of the present invention; has stronger desinsection; bactericidal action; simultaneously to diseases prevention; cure the disease good remarkable result is also arranged; because this protectant is the soup that plurality of Chinese is extracted, and has hundreds of composition, each composition is again an antibody; therefore; it is difficult for developing immunity to drugs, and also easily by plant absorbing, is difficult for decomposing; so property of medicine performance is lasting; this soup shows nutrient and the nitrogen phosphorus potassium that the various plants growth is arranged through chemical analysis, therefore can increase foliage fertilizer, contains multiple fiber in this soup; after using; except that ovum is killed in sterilization, can also dredge soil by pine to soil, therefore the effect of improving the soil is arranged.

This protectant is analyzed through test computer center of Nankai University, and analysis result sees Table 1:

Table 1: project molybdenum-iron zinc-copper strontium potassium silico-calcium is 2.34mg/l 73.4mg/l 52.6mg/l 0.31mg/l 11.54mg/l 18491mg/l 304mg/l 4612mg/l project magnesium manganese boron water salinity calcination loss crude fat nitrogen phosphorus 858mg/l 10.2mg/l 7.99mg/l 56.5% 1.4% 95.1% 7.71% 2369.9 μ g/l 1389.3 μ g/g as a result as a result

Can find out that from table 1 nutrition that this protectant contains is very high, growth and development of plants is highly advantageous to.

Protectant of the present invention has carried out the toxicity and the test of pesticide effectiveness, and its result is as described below:

1. acute toxicity experience provides report by Tianjin labour health occupation disease precaution﹠china institution, and the result shows:

Through two groups of contrasts of Wislar kind big white mouse male and female, through making coating, maximal tolerance dose LD5000mg/Kg is judged to be nontoxicly by national standard, and same per os is irritated stomach, and maximal tolerance dose LD is greater than 10000mg/kg, and the result judges nontoxic.

2. inferior chronic experiment, by Tianjin chemicals report that toxicological detection provides, the result shows:

Press 100mg/kg respectively through large ear rabbit male and female and blank three groups; 1000mg/kg and blank group; contamination through 12 weeks; all do not find the animal poisoning symptom for two groups; laboratory indexes and pathological tissue be no abnormality seen also, is safe with 100mg/kg as this protection dosage action-less dose therefore.

3. analysis of chromosome malformation and the experiment of bringing out property, micronucleus test, tertogenicity test, by the report that Tianjin labour health occupation disease precaution﹠china institution provides, the result shows, analyzes negative through small white mouse bone marrow stain body deformity, bringing out property experimental result shows that the result is negative.

Micronucleus test is the result show: two dosage of 5000mg/kg and 1000mg/kg can not make mouse produce micronucleus.

Tertogenicity test is the result show, gives pregnant mouse per os with the dosage of 1000mg/kg and irritates stomach, and the result is negative, tire mouse development growth is normal, do not have deformity and occurs.

4. toxicity test provides report by Agricultural University Of Shenyang, and the result shows:

To the green vegetables worm; yellow palm boat moth has the very strong virulence of tagging; to 4 age cabbage caterpillar dipping LC50 be 752.6ppm; contrast chlorophos dipping LC50 then is 4271.9ppm; protectant virulence is 5.7 times of chlorophos; the virulence of tagging for elm calligrapha is slightly larger than chlorophos, and dipping LC50 is also chrysomelid near the elm orchid substantially, to the susceptibility base value of protectant and chlorophos.

Two, the test of pesticide effectiveness:

1. field control effectiveness test; by the plant protection report that environmental protection provides of Beijing Academy of Agricultural Sciences; for studying thing is No. 11, white orchid; with 500,1000,1500 times of liquid of protectant; contrast phoxim 50EC is 1000 times of liquid and blank group, the results are shown in Table on 2 pairs of wild cabbages cabbage caterpillar test of pesticide effectiveness table 2 medicament and heavily handles after the pre-treatment and to handle insect population in the 1st day the 3rd day the 7th day

The insect population decline rate of surviving again control survival insect population decline rate control survival insect population decline rate control SSR insect population (corrected value) % effect insect population (corrected value) % effect insect population (corrected value) % effect detection is planted 500 times of liquid, 4 104 14 86.9 85.9 3 96.8 96.6 6 93.9 93.4 aA things and is protected 100 times of liquid 4 117 9 92.5 90.9 10 90.7 88.6 6 94.6 93.4 aA and protect 4 102 9 91.5 90.9 6 93.6 93.2 8 91.8 91.2 abA1000 times of liquid contrasts of 1500 times of liquid of agent, 4 108 18 83.8 81.8 14 85.8 84.1 15 85.3 85.3 bA phoxim 50EC (clear water) 4 96 99 88 91

The result shows that plant protection dilution agent 500-1500 doubly; soup was not as 1000 times of liquid of phoxim in first day; show and do not have quick-acting; but 500 times of liquid are handled beginning synergy in the 3rd day, and 500 times and 1000 times of liquid all reached 1000 times of liquid levels of phoxim in the 7th day, and omited; therefore recommending working concentration is that 500-1000 times of liquid is advisable; owing to not having quick-acting, suggestion is just used insect the length of time, also can be used in combination with the quick-acting agricultural chemicals.

2. to the test of pesticide effectiveness of control pine caterpillars, provide report,,, the results are shown in Table 3,4 with protectant and the contrast of sterilization chrysanthemum ester for 5-6 dendrolimus tabulaeformis in the age larva of the pine forest of trying the object forest farm by Chengde agricultural office forest prevention station

Handle the 72 hours worms of borer population 48 hours worms of 24 hours worms that live extremely after the dispenser extremely after killing dispenser before the dispenser of table 3 medicament after the dispenser

The borer population rate of living % borer population rate alive % borer population rate alive % plants 2000 times of liquid 45 11 75.6 3 92.9 0 100 of 1000 times of liquid 54 2 96.3 2 96.3 0 100 things guarantors and protects 3000 times of liquid of 3000 times of liquid of liquid, 35 11 68.6 1 96.9 0 100 sterilizations, 40 9 77.5 2 94.7 0 100% chrysanthemum ester CK 34 34 32 32

Table 4 medicament plant protection product sterilization chrysanthemum ester CK handles

Preceding worm 147 132 132 115 115 dispensers alive of 3000 times of liquid dispensers of 3000 times of liquid of 2000 times of liquid of 1000 times of liquid worm 0141 110 killing rate % 100 99.2 97.0 98.6 alive after 72 hours

The result shows: this protectant has good control efficiency to pine caterpillars, larva; they are 1000 years old; 2000; 3000 times of liquid after 72 hours killing rate be respectively 100%, 99.2%, 97%; the killing rate of 3000 times of liquid of control group is 98.6%; insecticidal effect exceeds 1.4-0.6%, and is generally speaking, very desirable to preventing and treating heavy pine caterpillars, larva effect.

3. prevent and treat Chinese scholar tree looper field control effectiveness test:

For the examination object is 15 years 4-5 Chinese scholar tree in age cankerworms on the livings state Chinese scholartree, kills 1500 times of liquid of missible oil and 20% with 1000,2000,3000 times of liquid of protectant dilution and 20% chrysanthemum and goes out and sweep 2000 times of liquid of profit and clear water contrasts, and carries out the test of pesticide effectiveness, the results are shown in Table 6.

The agent degree brings back to life and located (doubly) worm reason number worm that lives in 1 day 3 days 5 days 7 days and go down and proofread and correct the worm that lives and go down and proofread and correct the worm that lives and go down and proofread and correct the worm alive correction of going down before the dense medicine prevention effect of table 6 medicine

( ) ( ) ( ％ ) ( ％ ) ( ) ( ％ ) ( ％ ) ( ) ( ％ ) ( ％ ) ( ) ( ％ ) ( ％ ) 1000 2611 200 92.4 92.4 124 95.3 95.0 107 95.9 95.9 87 96.7 96.7 2000 2585 658 74.6 74.5 481 81.4 81.3 406 84.3 84.3 362 86.0 85.9 3000 2611 1001 61.6 61.5 791 69.7 69.6 672 74.2 74.2 633 75.7 75.620％ 2000 2553 185 92.7 92.7 117 95.4 95.4 97 96.2 96.2 51 98.0 98.0 ( ) 20％ ( 1500 2603 803 69.1 69.0 455 82.5 82.4 365 85.9 85.8 304 88.3 88.2 2643 2635 0.28 2632 0.41 2930 0.50 2626 0.637

Table 7 medicine is dense to be managed several 1 day 3 days 5 days 7 days for the multiple worm of control efficiency agent degree examination place (doubly)

The dead worm of worm that lives is proofreaied and correct the dead worm of worm alive dead worm correction worm alive and proofreaies and correct the dead worm correction of the worm that lives

Number (head) rate (%) preventive effect (%) number (head) rate (%) preventive effect (%) number (head) rate (%) preventive effect (%) is counted (head) rate (%) preventive effect (%) and is planted 1000 average 35 3.5 90.0 98.8 2.5 92.9 91.9 2.5 92.9 91.9 2.5 92.9 91.9 things and protect 2000 average 35 11 68.6 64.8 9.75 72.1 68.2 9.75 72.1 68.2 9.75 72.1 68.2 and protect agent 3000 average 35 15.75 55.0 49.5 13 62.9 57.8 13 62.9 57.8 13 62.9 57.8 and contrast clear water average 35 31.25 10.7 30.75 12.1 30.75 12.1 30.75 12.1

Table 6,7 results show that protectant has good control efficiency to the Chinese scholar tree looper, and very strong action of contace poison and certain stomach poison function are arranged, and promote concentration and are advisable with 1000-2000 times of liquid.

4. the anti-test that eliminates aphis proposes report by Vegetable Research center, Chengde, is that cucumber prevents eliminating aphis being object for the examination object, and protectant is with 500,1000, and 1500 times of liquid and 1000 times of liquid of 40% dimethoate emulsifiable concentrate and blank group are carried out, and the results are shown in Table 8.

Pesticide supplying effect before the table 8 medicament heavy dressing medicine (insect population go down rate) is handled multiple aphid amount

(head) 24 hours 7 days

The aphid that the lives % aphid that lives of going down is gone down and plants 500 times of liquid 3 230 15 93.47 12 94.78 things and protect 1000 times of liquid 3 160 11 93.22 12 92.50 and protect 1000 times of liquid of 1200 times of liquid of agent, 3 210 18 91.42 19 90.95 Rogor, 3 160 18 92.50 22 86.25CK (not dispenser) 3 230 250 350

Table 8 result shows that handling dispenser for three obtains 88.88% above insecticidal effect after 24 hours, and a little more than control group, and effective drug duration is long, insecticidal effect still reaches more than 87% after 7 days, to melon no any public hazards, adopt 1000-1200 times of solution spray, can reduce cost simultaneously.

5. to aphid; two-spotted spider mite; the toxicity test of green vegetables worm; providing report by Chinese Academy of Sciences's plant protection research, is to cultivate on the rape to choose the aphid turnip aphid for the examination object, cultivates two-spotted spider mite on the bean seedlings; cabbage caterpillars such as cabbage; protectant variable concentrations group and clear water control group the results are shown in Table 9, table 10.Toxicity test table 9 drug dose examination as a result borer population death toll title to aphid

(ppm) become if assembly is protected 6 142 292 434 130 275 405 and protected agent 3 78 173 251 65 159 224 if always plant 12 112 165 277 112 162 274 things

1.5 82 141 223 53 112 165

0.75 91 81 172 70 62 132

0.375 67 104 171 28 77 10540% 1,600 78 137 215 73 137 210 oxygen fruit 800 75 175 250 66 170 236

400 108 143 251 88 139 227

200 97 284 381 45 247 292

100 55 178 233 29 131 160

50 66 209 275 15 169 184

CK 97 60 157 4 10 14

Toxicity test table 10 chemicals treatment dosage (ppm) the examination as a result borer population death toll of two-spotted spider mite is planted 0.188 175 43 thing, 0.375 128 46 guarantor 0.75 105 44 protect 1.5 177 82 dose 3.0 178 85

6.0 159 86

12.0 178 109 40% 25 194 81 oxygen, 50 106 40 happy 100 111 63 fruits 200 93 60

400 72 64

800 116 112

1,600 142 142 CK plain boiled waters 72 5

30 15 10 14 things, 15 18 11 14 guarantors 7.5 15 48 were planted in the as a result table 11 drug dose examination borer population death toll processing (ppm) of toxicity test of cabbage caterpillar in 24 hours 48 hours protect 1.875 15 36 dose of 0.469 15 1 440% 4,000 15 15 15 oxygen, 2,000 16 12 15 happy 1,000 15 29 fruit 250 15 37

62.50 15 0 3CK clear water 15 22

Result of the test shows that three kinds of examination worms are had very strong toxic action, significantly be better than the contrast agents omethoate, virulence to the vegetable aphid worm is 373 times (adult) and 117.4 times (larva) of omethoate, to the virulence of two-spotted spider mite is 21.5 times of omethoate, is 73.5 times (24 hours) and 97.5 times (48 hours) of omethoate to the virulence of green vegetables worm.The strongest through statistical analysis to aphid lethality, the toxic action of cabbage caterpillar is taken second place, inferior to the toxic action of two-spotted spider mite.

6. control cotton disease field trial provides report by Hebei province's Cotton Research Institute

The upright charcoal red and black of the different germ classification of table 12 medicament soup bacteriostasis rate % concentration of treatment is withered and yellow

The rotten root of withered subcutaneous ulcer withers

Bacterium bacterium mycocriny bacterium bacterium

Bacterium is planted 500 times of liquid 7.0 11.75 7.0 10.75 7.0 7.25 of 300 times of liquid, 23.0 7.0 20.5 7.0 11.5 things guarantor and protects 500 times of liquid of 800 times of liquid of agent, 15.5 7.0 14.0 7.0 7.0 carbendazim, 000000 pairs of cotton anthracnose bacterium of 45.5 21.5 44.0 24.5 21.5 blank CK and black root rot bacterium power mensuration table 13

The rotten bacterium processing of the rotten bacterium anthrax-bacilus of colony diameter (mm) bacteriostasis rate (%) drug concentration anthrax-bacilus black root black root is planted 200 times of liquid 37.5 20.0 64.21 62.71 of 100 times of liquid, 32.25 15.25 73.59 78.32 things guarantor and is protected 400 times of liquid of agent 42.25 25.0 54.67 41.73

800 times of liquid 46.25 27.0 45.68 32.03 blank CK 62.75 32.75

Prevent and treat fusarium wilt test of pesticide effectiveness table 14 medicament soup strain incidence of disease disease and refer to that preventive effect concentration of treatment number (%) (%) plants 500 times of liquid 102 49.12 44.04 31.95 things and protect 1000 times of liquid 97 54.63 48.13 25.63 and protect 1500 times of liquid of agent, 101 71.52 48.64 24.85 blank CK and irritate clear water 90 7.0 64.72

Control fusarium wilt test of pesticide effectiveness table 15 medicament soup strain as a result incidence of disease disease refers to that preventive effect title concentration numbers (%) (%) plants 500 times of liquid 94 42.65 32.61 48.09 things and protect 1000 times of liquid 99 54.08 44.86 28.59 and protect 1500 times of liquid of agent, 98 65.25 51.62 17.83 blank CK and irritate clear water 41 76.61 62.82

Preventing and treating verticillium wilt test of pesticide effectiveness table 16 medicament soup strain as a result incidence of disease disease names and claims concentration numbers (%) to plant 500 times of liquid 85 74.34 40.05 things to protect 800 times of liquid 55 76.64 42.89 and protect 44.8825% 500 times of blank CK 85 89.05 59.94 of liquid 85 81.82 48.81 carbendazim of 300 times of liquid of agent 53 77.68

From table 12,13,14,15,16 results show, protect liquid to fusarium wilt, verticillium wilt, and diseases such as bacterium disease have certain anti-treatment effect or inhibitory action.

Compared with the prior art the technology of the present invention has following advantage and effect:

A) have desinsection, sterilization, diseases prevention, the multiple function of curing the disease is the plant protection product of one, its effect is remarkable, simultaneously soil is had good improving effect, can kill the bacterium worm's ovum and the loose vegetables soil of soil;

B) nontoxic to people and animals, harmless, pollution-free, no residual hazard, belonging to public nuisance-free agricultural chemicals is the optimal medicament of green plants;

C) to the Chinese scholar tree looper, the pine tar caterpillar, cotton bollworm, two spotted spider mite, cabbage caterpillar, mythimna separata, aphid, pine forest is chrysomelid long-acting, and does not develop immunity to drugs, to the desirable especially medicament of farming industry that closes on harvest time;

D) product stability is good, and it is thermally-stabilised good, 54 ℃ ± 2, and fortnight resolution ratio≤5%, cold stability folds thing 0 ℃ ± 1, seven day nothing, and acidity is with H ₂SO ₄≤ 1%;

E) raw material is easy to get, and the preparation method is simple.

F) contain various nutrients, N especially, P, K content is very high, and plant leaf surface is had the growth of promotion effect.

Embodiment 1:

Get selected kuh-seng 30kg, tobacco 50kg, tuber of stemona 4kg, golden cypress 20kg, yellow Siberian cocklebur 10kg, coptis 7kg, isatis root 15kg add the water of 6 times of drug weight respectively, decoct in the extractor of packing into to extract soup in 3 hours, isolate soup again, add medicine more respectively and weigh 8 times of water continuation decoctions extraction in 2 hours soup, isolated soup and soup merging for the first time carry out the vacuum concentration soup after the filtration, obtain 54.1 kilograms of soups, its Baume degrees is 12, feeds in the edible alcohol jar with pump again, carries out " wine is heavy ", the control soup contains edible alcohol 12kg, separate alcohol and reclaim adding turpentine oil 5kg in soup, 4017 emulsifier 15kg, stabilizing agent 8kg, transdermal agent 5kg fully mixes, and is product.

Embodiment 2:

Get selected kuh-seng 40kg, tobacco 40kg, tuber of stemona 2kg, golden cypress 15kg, yellow Siberian cocklebur 15kg, coptis 2kg, isatis root 10kg add the water of 7 times of drug weight respectively, decoct in the extractor of packing into to extract soup in 3.5 hours, isolate soup again, add medicine more respectively and weigh 6 times of water continuation decoctions extraction in 2.5 hours soup, isolated soup and soup merging for the first time carry out the vacuum concentration soup after the filtration, obtain 49.6 kilograms of soups, its Baume degrees is 11, feeds in the edible alcohol jar with pump again, carries out " wine is heavy ", the control soup contains edible alcohol 8kg, separate alcohol and reclaim adding turpentine oil 10kg in soup, 4017 emulsifier 10kg, stabilizing agent 6kg, transdermal agent 10kg fully mixes, and is product.

Embodiment 3:

Get selected kuh-seng 50kg, tobacco 30kg, tuber of stemona 6kg, golden cypress 10kg, yellow Siberian cocklebur 20kg, coptis 5kg, isatis root 5kg add the water of 9 times of drug weight respectively, decoct in the extractor of packing into to extract soup in 4 hours, isolate soup again, add medicine more respectively and weigh 5 times of water continuation decoctions extraction in 3 hours soup, isolated soup and soup merging for the first time carry out the vacuum concentration soup after the filtration, obtain 41.58 kilograms of soups, its Baume degrees is 10, feeds in the edible alcohol jar with pump again, carries out " wine is heavy ", the control soup contains edible alcohol 5kg, separate alcohol and reclaim adding turpentine oil 15kg in soup, 4017 emulsifier 5kg, stabilizing agent 5kg, transdermal agent 15kg fully mixes, and is product.

Claims (2)

1, a kind of plant protection product is characterized in that it is made up of the raw material of following weight ratio, and each component consumption proportion (by weight) is:

The yellow Siberian cocklebur 10-20 of kuh-seng 30-50 part tobacco 30-50 part tuber of stemona 2-6 part golden cypress 10-20 part part

Coptis 2-7 part isatis root 5-15 part turpentine oil 5-15 part edible alcohol 5-15 part

Transdermal agent 5-15 part 4017 emulsifier 5-15 part stabilizing agent 5-8 parts.

2, the preparation method of plant protection product is characterized in that it is undertaken by the following step:

A) selected kuh-seng, tobacco, the tuber of stemona, golden cypress, Huang Ling, the coptis, each Chinese medicine of isatis root;

B) with the kuh-seng 30-50 weight portion of (a), tobacco 30-50 weight portion, tuber of stemona 2-6 weight portion, golden cypress 10-20 weight portion, yellow Siberian cocklebur 10-20 weight portion, coptis 2-7 weight portion, isatis root 5-15 weight portion, respectively through washing, fragmentation or section add the heavy 6-9 of medicine water doubly respectively and decoct 3-4 hour extraction soup in extractors, and separate various soups in various medicines, its dregs of a decoction add the heavy 5-8 of medicine water doubly again and carry out secondary decoction 2-3 hour, and the soup of separation merges with a soup and mixes;

C) the various admixing medical solutions with (b) filter respectively, vacuum concentration, the Baume degrees that makes soup is squeezed in the edible alcohol jar with pump then and is carried out " wine is heavy " at 10-12, makes when containing edible alcohol 5-15 weight portion in the soup and separates, and obtains intermediate products;

D) in intermediate products, add turpentine oil 5-15 weight portion and transdermal agent 5-15 weight portion, 4017 emulsifier 5-15 weight portions, stabilizing agent 5-8 weight portion fully mixes the back filling bottle;

E) test vanning, warehouse-in.