CN118161584A - Traditional Chinese medicine composition for treating fever cough and expectoration - Google Patents
Traditional Chinese medicine composition for treating fever cough and expectoration Download PDFInfo
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- CN118161584A CN118161584A CN202410301041.8A CN202410301041A CN118161584A CN 118161584 A CN118161584 A CN 118161584A CN 202410301041 A CN202410301041 A CN 202410301041A CN 118161584 A CN118161584 A CN 118161584A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating cough with fever and expectoration, which is prepared from the following raw materials in parts by weight: 5-15 parts of kelp, 5-10 parts of hawthorn, 5-10 parts of sea buckthorn, 10-20 parts of roxburgh rose, 5-15 parts of mint, 15-20 parts of dried orange peel, 5-15 parts of wrinkled gianthyssop herb, 5-20 parts of platycodon root, 15-25 parts of papaya, 5-10 parts of mulberry leaf, 5-10 parts of almond, 10-20 parts of perilla, 10-20 parts of kudzuvine root, 10-20 parts of cape jasmine, 15-25 parts of villous amomum fruit, 15-20 parts of radish seed, 5-10 parts of astragalus root, 5-15 parts of cogongrass rhizome, 5-20 parts of chrysanthemum, 5-20 parts of boat-fruited sterculia seed, 5-20 parts of dandelion, 5-20 parts of reed rhizome, 5-15 parts of elsholtzia and 15-25 parts of honeysuckle. The traditional Chinese medicine composition has the effects of clearing heat and cooling down the heat, nourishing yin and cooling blood, dispersing wind heat, promoting diuresis, eliminating dampness and removing cataract, detoxifying, nourishing vital qi and strengthening vital qi to eliminate pathogenic factors.
Description
Technical Field
The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition for treating fever cough and expectoration.
Background
Cough with fever and sputum is a common disease of respiratory tract, is mostly caused by bacterial and/or viral infection, is clinically accompanied with various symptoms such as headache, cough, fever and the like, and can endanger life safety when serious. At present, most of clinical treatments adopt antibiotics or antiviral drugs, but the drug resistance is easy to generate, which is unfavorable for the control of the disease condition, or the injury of liver and kidney or stomach. With recent advances in modern pharmacology, traditional Chinese medicine has made good progress in treating respiratory diseases. The traditional Chinese medicine considers that respiratory diseases belong to the category of lung system diseases with phlegm heat resistance and lung syndrome, and symptoms are fever, cough, uncomfortable expectoration, sore throat and the like. It is caused by pathogenic wind-heat affecting the lung, heat obstructing the lung qi and loss of lung qi. The traditional Chinese medicine treatment method of respiratory system diseases is rich and rich, has characteristics, and is mainly focused at present: strengthening body resistance, regulating immunity, preventing infection, resisting virus, improving clinical symptoms, shortening disease course, relieving toxic and side effects of western medicines, and has remarkable curative effects on external chronic cough, chronic obstructive pulmonary disease, bronchial asthma and pulmonary heart disease in remission stage.
However, most of traditional Chinese medicine compounds for treating respiratory diseases are cold and cool formulas, cannot be taken for a long time, and cannot tonify healthy qi due to lack of nourishment to spleen and stomach, so that the body cannot effectively resist exogenous evils, and the treatment effect is unsatisfactory. Yu Li, provides a Chinese herbal compound in < application analysis of Chinese herbal tea in pneumonia prevention and treatment >, which has the effects of immunoregulation and anti-inflammatory, can enhance the body resistance and resist exogenous evil, but needs to be combined with acupuncture treatment when relieving clinical symptoms, especially fever. It is necessary to provide a Chinese medicinal preparation which has not only remarkable effect in enhancing body resistance but also advantage in improving clinical symptoms.
Disclosure of Invention
In order to solve the problems, the invention provides a traditional Chinese medicine composition for treating fever cough and expectoration, which is prepared from the following raw materials in parts by weight:
5-15 parts of kelp, 5-10 parts of hawthorn, 5-10 parts of sea buckthorn, 10-20 parts of roxburgh rose, 5-15 parts of mint, 15-20 parts of dried orange peel, 5-15 parts of wrinkled gianthyssop herb, 5-20 parts of platycodon root, 15-25 parts of papaya, 5-10 parts of mulberry leaf, 5-10 parts of almond, 10-20 parts of perilla, 10-20 parts of kudzuvine root, 10-20 parts of cape jasmine, 15-25 parts of villous amomum fruit, 15-20 parts of radish seed, 5-10 parts of astragalus root, 5-15 parts of cogongrass rhizome, 5-20 parts of chrysanthemum, 5-20 parts of boat-fruited sterculia seed, 5-20 parts of dandelion, 5-20 parts of reed rhizome, 5-15 parts of elsholtzia and 15-25 parts of honeysuckle.
Further, the traditional Chinese medicine is prepared from the following raw materials in parts by weight:
10 parts of kelp, 8 parts of hawthorn, 8 parts of sea buckthorn, 10 parts of roxburgh rose, 10 parts of mint, 20 parts of dried orange peel, 10 parts of wrinkled gianthyssop herb, 15 parts of platycodon root, 25 parts of papaya, 7 parts of mulberry leaf, 8 parts of almond, 11 parts of perilla, 11 parts of kudzuvine root, 15 parts of cape jasmine fruit, 25 parts of villous amomum fruit, 20 parts of radish seed, 9 parts of astragalus root, 14 parts of cogongrass rhizome, 14 parts of chrysanthemum, 6 parts of boat-fruited sterculia seed, 15 parts of dandelion, 14 parts of reed rhizome, 13 parts of elsholtzia and 25 parts of honeysuckle.
Further, the cogongrass rhizome is fresh cogongrass rhizome, and the reed rhizome is fresh reed rhizome.
Further, the preparation is prepared by taking medicinal powder of the raw material medicine or water or organic solvent extract of the raw material medicine as an active ingredient and adding pharmaceutically acceptable auxiliary materials.
Still further, the formulation is an oral formulation.
Still further, the oral preparation comprises granules, solutions, pills, powders, pastes, tablets.
The invention also provides a preparation method of the traditional Chinese medicine composition, which comprises the following steps:
(1) Weighing the raw materials according to the proportion;
(2) Grinding the raw materials into powder, or extracting with water or organic solvent, and adding adjuvants or auxiliary components commonly used in medicine.
The invention finally provides application of the traditional Chinese medicine composition in preparing a medicine for treating fever cough and expectoration.
Further, the medicine is a medicine for relieving fever and/or resolving phlegm and relieving cough.
Further, the medicine has the effects of eliminating pathogenic factors and strengthening body resistance.
The fresh cogongrass rhizome refers to cogongrass rhizome which is not processed after being collected.
The fresh reed rhizome refers to reed rhizome which is not processed after collection.
The traditional Chinese medicine composition disclosed by the invention has the effects of removing qi and regulating the middle warmer, removing the heat in the chest, reversing qi, treating laryngeal and pharyngalgia, tonifying deficiency and eliminating phlegm, breaking the syndrome of the abdominal mass, clearing upper phlegm through mint, relieving sore throat and diaphragmatic, treating wind heat, clearing wind and cooling through chrysanthemum, removing chest restlessness and benefiting five vessels, clearing heat and detoxicating through dandelion, eliminating carbuncles and resolving masses, dispelling wind and heat through mulberry leaves, cooling and relieving exterior syndrome, clearing lung and moistening dryness through the lung, and the six effects of clearing heat and detoxicating, ventilating and activating lung qi, dispelling wind and cooling are achieved, so that the traditional Chinese medicine composition is beneficial to harmonizing ying and wei, clearing heart fire and relieving restlessness. Has the functions of clearing away heat and toxic material, cooling blood and expelling toxin for the inflammation and heat syndrome which are accumulated in the body and are formed in viscera.
Semen Scaphii Lychnophori has effects of clearing lung heat, relieving sore throat, and flos Lonicerae clearing pathogenic fire, removing Wen Yihui foul evil, semen Armeniacae amarum relieving cough, eliminating phlegm, moistening lung, lalang grass rhizome clearing heat, cooling blood, clearing heat, relieving sore throat, and cough, and can be used for relieving sore throat and cough, removing toxic substances, cooling blood, and relieving fever.
Fructus Gardeniae has effects of clearing heat and promoting urination, cooling blood and removing toxic substances, thallus laminariae has effects of promoting diuresis, removing dampness by draining water, removing food stagnation and softening hard masses, fructus Hippophae has effects of relieving cough and eliminating phlegm, resolving food stagnation, promoting blood circulation and removing blood stasis, fructus Rosae Normalis has effects of clearing heat and removing toxic substances and eliminating dampness, and can be used for dredging diuresis.
Herba Moslae can stop four times typhoid fever, lower qi, relieve dysphoria and heat, treat vomiting and cold, herba Pogostemonis can dispel cold, damp, summer-heat and damp Yu Reshi heat, tonify qi and replenish stomach qi, and the two are matched with fragrance to induce resuscitation, relieve headache and head distress, and enhance vital qi of human body.
The radix puerariae has the effects of relieving exterior syndrome, relieving muscles, removing pathogenic factors, promoting digestion, promoting the circulation of qi, invigorating stomach, expelling diaphragmatic, removing blood stasis, relieving stuffiness and distention, digesting food grains by fructus amomi, warming spleen and stomach, promoting qi circulation, regulating middle warmer, removing stagnancy, supplementing qi, promoting circulation of qi, astringing lung, regulating stomach, regulating spleen, removing liver fire, removing food stagnation, quenching thirst, promoting circulation of qi, expelling phlegm, benefiting lung, expelling radish seed, reducing phlegm, relieving roar dyspnea, clearing heat, promoting salivation, relieving restlessness, promoting urination, removing stomach heat, relieving vomiting, treating lung abscess, expelling pus, and the eight are matched with spleen and stomach, invigorating spleen, removing dampness, warming middle warmer, dispelling cold, lowering adverse qi, relieving vomiting, warming middle warmer, and descending qi to guide down evil.
The whole formula takes fructus amomi, radish seed, papaya, dried orange peel and honeysuckle as monarch, peppermint, wrinkled giant hyssop, platycodon grandiflorum, almond, perilla, kudzuvine root, cape jasmine, astragalus root, cogongrass rhizome, dandelion, reed rhizome and elsholtzia as ministerial, kelp, hawthorn, sea buckthorn and roxburgh rose as auxiliary materials, chrysanthemum, boat-fruited sterculia seed and mulberry leaf as auxiliary materials, has the effects of clearing heat and detoxicating, ventilating and activating lung qi, dispelling wind and cooling blood and expelling toxin, is beneficial to clearing heart and relieving restlessness, relieving sore throat, and is beneficial to strengthening spleen and stomach and eliminating dampness, warming middle-jiao and dispelling cold and warming middle-jiao and descending qi to promote the discharge of the external evil on one hand and the center of the spleen and stomach on the other hand helps to enhance the absorption of medicines so as to form positive circulation. Meanwhile, by guiding qi downward, the cough caused by the upward reverse qi movement can be reduced.
Animal experiments prove that: the traditional Chinese medicine composition has the effects of clearing heat and allaying fever, nourishing yin and cooling blood, and dispersing wind-heat, has remarkable effects on reducing the body temperature during fever, and also has the effects of promoting diuresis, eliminating dampness and removing cataract, and has remarkable phlegm-resolving and cough-relieving effects. Not only has advantages in improving clinical symptoms, but also has outstanding advantages in enhancing organism anti-inflammatory and immunoregulation, and has the effects of detoxification, vital qi nourishing, body resistance strengthening and pathogenic factor eliminating.
It should be apparent that, in light of the foregoing, various modifications, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.
The above-described aspects of the present invention will be described in further detail below with reference to specific embodiments in the form of examples. It should not be understood that the scope of the above subject matter of the present invention is limited to the following examples only. All techniques implemented based on the above description of the invention are within the scope of the invention.
Detailed Description
The raw materials and equipment used in the specific embodiment of the invention are all known products and are obtained by purchasing commercial products, wherein the preparation process of the granules, solutions, pills, tablets, powder or paste prepared from the composition of the invention is mature, and the preparation can be prepared by referring to the conventional method in the prior art.
EXAMPLE 1 preparation of the medicament of the invention
The formula comprises the following components: 10g of kelp, 8g of hawthorn, 8g of sea buckthorn, 10g of roxburgh rose, 10g of peppermint, 20g of dried orange peel, 10g of wrinkled gianthyssop herb, 15g of platycodon root, 25g of papaya, 7g of mulberry leaf, 8g of almond, 11g of perilla, 11g of kudzuvine root, 15g of cape jasmine fruit, 25g of villous amomum fruit, 20g of radish seed, 9g of astragalus root, 14g of cogongrass rhizome, 14g of chrysanthemum, 6g of boat-fruited sterculia seed, 15g of dandelion, 14g of reed rhizome, 13g of elsholtzia and 25g of honeysuckle.
The preparation method comprises the following steps: weighing the raw materials according to the proportion, adding 15 times of water, soaking for 20min, decocting for 20-30 min, filtering, adding 15 times of water into residues, repeatedly decocting and filtering for 1 time, combining the two filtrates, and concentrating under reduced pressure to obtain decoction.
EXAMPLE 2 preparation of the medicament of the invention
The formula comprises the following components: kelp 5g, haw 5g, sea buckthorn 5g, roxburgh rose 10g, peppermint 5g, dried orange peel 5g, wrinkled gianthyssop 5g, balloonflower 5g, papaya 5g, mulberry leaf 5g, almond 5g, perilla 10g, kudzuvine root 10g, cape jasmine 10g, amomum fruit 5g, radish seed 5g, astragalus root 5g, cogongrass rhizome 5g, chrysanthemum 5g, boat-fruited sterculia seed 5g, dandelion 5g, reed rhizome 5g, elsholtzia 5g, honeysuckle 5g
The preparation method comprises the following steps: weighing the raw materials according to the proportion, adding 12 times of water to soak for 20min, decocting for 20-30min, filtering, adding 12 times of water into residues, repeatedly decocting and filtering for 1 time, combining the two filtrates, concentrating the filtrate under reduced pressure to obtain thick paste, adding common auxiliary materials on medicines, and preparing into tablets.
EXAMPLE 3 preparation of the medicament of the invention
The formula comprises the following components: 15g of kelp, 10g of hawthorn, 10g of sea buckthorn, 20g of roxburgh rose, 15g of peppermint, 20g of dried orange peel, 15g of wrinkled gianthyssop herb, 20g of platycodon root, 10g of papaya, 10g of mulberry leaf, 10g of almond, 20g of perilla, 20g of kudzuvine root, 20g of cape jasmine fruit, 10g of villous amomum fruit, 20g of radish seed, 10g of astragalus root, 15g of cogongrass rhizome, 20g of chrysanthemum, 20g of boat-fruited sterculia seed, 20g of dandelion, 20g of reed rhizome, 15g of elsholtzia and 15g of honeysuckle flower
The preparation method comprises the following steps: weighing the raw materials according to the proportion, adding 10 times of water to soak for 20min, decocting for 20-30 min, filtering, adding 10 times of water into the residues, repeatedly decocting and filtering for 1 time, combining the two filtrates, concentrating the filtrate under reduced pressure to obtain thick paste, adding common auxiliary materials on medicines, and preparing into granules.
The composition of the invention is a formulation with good effect, which is formed by a large number of screening, and the curative effect is poor when the traditional Chinese medicine taste is replaced by other medicine taste, and the beneficial effects of the invention are further illustrated by the partial comparison group listed in the test examples.
Experimental example 1 pharmacodynamic study based on animal experiments
In experiments, 9 or 10 groups are set for drug effect observation, specifically, in addition to a blank group, a model group, a control group and a 1 group (the drug prepared in example 1), the formulation in example 1 is split to form another 6 control groups, and the corresponding split formulas and numbers are respectively as follows:
Group 2: 20g of dried orange peel, 15g of platycodon grandiflorum, 10g of mint, 14g of chrysanthemum, 15g of dandelion and 7g of mulberry leaf
Group 3: boat-fruited sterculia seed 6g, dried orange peel 20g, apricot kernel 8g
Group 4: 15g of cape jasmine fruit, 10g of kelp, 8g of sea buckthorn and 10g of roxburgh rose
Group 5: 13g of elsholtzia, 10g of wrinkled giant hyssop and 9g of astragalus root
Group 6: radix Puerariae 11g
7 Groups: 8g of hawthorn, 25g of fructus amomi, 20g of dried orange peel, 25g of papaya, 11g of perilla and 20g of radish seed
The formulation of each split control group was prepared into decoction containing the same crude drug amount as that of the split control group according to the preparation method of example 1.
1. Experiment for clearing heat and abating fever
1. Method of
As a result of a large number of studies, LPS is considered to be an active ingredient of endotoxin of gram-negative bacteria, has high water solubility, is a bacterial heat source with a strong effect, and is similar to the type of fever caused by clinical infectious inflammation in that the type of fever induced by LPS is shown as biphasic fever or triphasic fever. Therefore, 80 healthy Kunming mice with normal development and no fever lesions are selected and randomly divided into 10 groups (blank group, model group, control group and 1-7 groups), 8 mice in each group have a weight of about 18-22 g, and other groups of mice except the blank group adopt LPS to induce fever modeling.
And the water is not forbidden after fasted for 8 hours before molding. The blank group and the model group are filled with physiological saline according to the ratio of 0.2mL/10g, the body temperature is measured for 1 time every 0.5h, and the continuous monitoring is carried out for 10h. Except for the blank group, the other groups respectively inject LPS (20 mug/kg) into the abdominal cavity of the mice to induce animals to generate heat, and the stomach is irrigated by different medicines while molding; the control group was dosed with acetaminophen at 1.5mg/20 g; 1 to 7 groups of Chinese medicinal decoction are infused according to groups, and the dosage is 0.2mL/10g. The body temperature was measured 1 time every 0.5h after LPS injection, and the monitoring was continued for 10h, and the maximum body temperature elevation DeltaT (difference between the body temperature at the time of fever and the basal body temperature) was recorded.
2. Results
The specific results are shown in tables 1 to 3
TABLE 1 measurement of DeltaT (. Degree. C.) data at 0.5h intervals
TABLE 2 measurement of DeltaT (. Degree. C.) data at 0.5h intervals
TABLE 3 measurement of DeltaT (. Degree. C.) data at 0.5h intervals
Note that: p is less than or equal to 0.05 compared with a blank group; the ratio of the material to the model group is #p is less than or equal to 0.05; compared with the #1 group, the p is less than or equal to 0.05.
From the above results, it can be seen that: for mice with a model of fever induced by LPS, the prescription provided by the invention can play a role in reducing temperature within 1.5 hours and lasts for 8.5 hours, and has definite effects of reducing body temperature, relieving fever and bringing down fever, and is quick in action speed and strong in action. After the components of the invention are split differently, the antipyretic and antipyretic effects of the respective split items are not obvious. Therefore, the prescription has the effects of clearing heat, reducing fever, nourishing yin, cooling blood and dispersing wind-heat through specific medicinal components.
2. Phlegm resolving experiment
1. Method of
72 Healthy Kunming mice with normal development and no fever lesions are selected, the weight of the mice is about 18-22 g, the mice are randomly divided into 9 groups (blank group, control group and 1-7 groups), and 8 mice in each group are subjected to a tracheal phenol red excretion experiment. The experimental principle is that after phenol red is used as an indicator, if a mouse takes a medicine with the function of resolving phlegm after the phenol red is injected into the abdominal cavity of the mouse, the bronchogenic secretion of the mouse is increased, so that the excretion amount of the phenol red in the mucous membrane of the respiratory tract is increased, the excretion of the phenol red is more, the expectoration of the sputum is predicted to be promoted, and the phlegm resolving function of the medicine can be deduced from the influence of the experimental medicine on the excretion amount of the intratracheal phenol red.
The blank group is filled with normal saline according to 0.2mL/10g, the control group is compound fresh bamboo juice, and 1-7 groups are filled with corresponding traditional Chinese medicine decoction according to grouping, and the dosage is 0.2mL/10g. Fasted for 8h before the experiment, 30min after administration, each mouse was intraperitoneally injected with 0.7mL of 2.5% phenol red solution, immediately sacrificed after 30min, fixed in position, the trachea was separated, 0.5mL of 5% NaHCO 3 solution was extracted with a 1mL syringe, the trachea was flushed 3 times by inserting about 0.3-0.5 cm into the trachea from the thyroid cartilage, 3 times of aspiration back and forth each time, the 3 times of eluates were combined, centrifuged for 15min, the supernatant was diluted 5 times with distilled water, and the phenol red absorption (A) was measured at a wavelength of 546nm with an ultraviolet spectrophotometer.
2. Results
The specific results are shown in Table 4
Table 4 comparison of tracheal phenol Red excretion in mice of each group
Note that: p is less than or equal to 0.05 compared with a blank group; compared with the #1 group, the p is less than or equal to 0.05.
From the above results, it can be seen that: the prescription can promote the secretion of the tracheal phenol red of the mice, and has obvious phlegm-resolving effect and reduces phlegm dampness, and after the prescription is split differently, the phlegm-resolving effect of the split items is not obvious. Therefore, the prescription of the invention can take the functions of spleen and stomach transportation and transformation into account through specific medicine composition, and has the effects of dredging channels, resolving dampness and removing cataract.
3. Acute upper respiratory tract infection simulation experiment
1. Method of
Acute upper respiratory tract infection belongs to the category of external infection of traditional Chinese medicine, no matter whether the external infection is wind-cold or wind-heat or epidemic disease, the external pathogenic factors disturb the lung qi to lose the benefit, exterior cold can enter the interior to transform heat, and the heat burns the body fluid to form phlegm heat, and the pathogenic heat flows along the channel to form lung heat. The nature of exogenous pathogenic factors is considered by traditional Chinese medicine to be due to the internal cause of 'deficiency of healthy qi'. Therefore, the Chinese medicinal composition aims at strengthening body resistance to eliminate pathogenic factors, improving the immunity of the organism, inhibiting bacteria and resisting inflammation, and controlling the illness state, relieving symptoms and shortening the illness course by regulating the immunity of the organism.
80 Healthy Kunming mice with normal development and no fever lesions are selected, the weight of the mice is about 18-22 g, the mice are randomly divided into 10 groups (blank group, model group, control group and 1-7 groups), 8 mice in each group except the blank group, 50 mu l of staphylococcus aureus bacterial liquid is slowly dripped from the nasal cavity of the mice in the rest groups under the state of diethyl ether anesthesia, and after the mice are automatically inhaled, the mice begin to be treated by medicaments after molding for 1 hour. Wherein the blank group and the model group are filled with physiological saline according to 0.2mL/10g, and the control group is filled with azithromycin according to 1.5mg/20g.1 to 7 groups of Chinese medicinal decoction are infused according to groups, and the dosage is 0.2mL/10g. Fasted for 8 hours before the experiment, the administration is carried out for 1 time/d for 7 days, and the materials are taken for 7 days after the modeling to detect TNF-alpha and IL-6.
2. Results
The specific results are shown in tables 5 to 6.
TABLE 5 Lung TNF-alpha content (pg/ml) in mice of each group
Note that: p is less than or equal to 0.05 compared with a blank group; the ratio of the material to the model group is #p is less than or equal to 0.05; compared with the #1 group, the p is less than or equal to 0.05.
TABLE 6 Lung IL-6 content (pg/ml) in mice of each group
Note that: p is less than or equal to 0.05 compared with a blank group; the ratio of the material to the model group is #p is less than or equal to 0.05; compared with the #1 group, the p is less than or equal to 0.05.
TNF-alpha has various activities such as inflammation, immunity, internal environment stabilization and the like, and TNF-alpha and IL-6 are important links in an organism immunity regulation system after infection, have the effect of improving organism immunity response and have the important effect of resisting infection. Experimental results show that compared with healthy and active mice in a blank group, the concentration and content of TNF-alpha and IL-6 in a model group are improved, the mice are poor in mental state, are curled, have poor response to the surrounding environment, have upright and matt hair, have increased conjunctival secretion of partial mice, have symptoms of cough caused by shortness of breath, and are positively correlated with the degree of fever caused by clinical verification infection. In mice treated by the drug lavage, the content of TNF-alpha and IL-6 in the lung tissue homogenate of mice in the control group and the group 1 is obviously reduced compared with that in the model group, and the mice have gradually improved spirit, stable respiration and no cough symptom. Compared with other experimental groups after the group prescription is disassembled, the group 1 is obviously superior to other groups, which proves that the formula of the invention can activate the immune mechanism of the organism in a short time, strengthen the anti-inflammatory and immunoregulatory effects of the organism, shorten the anti-inflammatory process of the organism and accelerate the recovery of respiratory tract infectious diseases, but other formulas after the group prescription is disassembled have no obvious effect.
From the experimental results, it can be seen that: the prescription has the effects of detoxification, vital qi nourishing, vital qi strengthening and evil eliminating through specific medicine composition, has advantages in improving clinical symptoms of cough with fever and phlegm, and has outstanding advantages in enhancing organism anti-inflammatory and immunoregulation.
Claims (10)
1. A traditional Chinese medicine composition for treating fever cough and expectoration is characterized in that: the traditional Chinese medicine is prepared from the following raw materials in parts by weight:
5-15 parts of kelp, 5-10 parts of hawthorn, 5-10 parts of sea buckthorn, 10-20 parts of roxburgh rose, 5-15 parts of mint, 15-20 parts of dried orange peel, 5-15 parts of wrinkled gianthyssop herb, 5-20 parts of platycodon root, 15-25 parts of papaya, 5-10 parts of mulberry leaf, 5-10 parts of almond, 10-20 parts of perilla, 10-20 parts of kudzuvine root, 10-20 parts of cape jasmine, 15-25 parts of villous amomum fruit, 15-20 parts of radish seed, 5-10 parts of astragalus root, 5-15 parts of cogongrass rhizome, 5-20 parts of chrysanthemum, 5-20 parts of boat-fruited sterculia seed, 5-20 parts of dandelion, 5-20 parts of reed rhizome, 5-15 parts of elsholtzia and 15-25 parts of honeysuckle.
2. The traditional Chinese medicine composition according to claim 1, wherein: the traditional Chinese medicine is prepared from the following raw materials in parts by weight:
10 parts of kelp, 8 parts of hawthorn, 8 parts of sea buckthorn, 10 parts of roxburgh rose, 10 parts of mint, 20 parts of dried orange peel, 10 parts of wrinkled gianthyssop herb, 15 parts of platycodon root, 25 parts of papaya, 7 parts of mulberry leaf, 8 parts of almond, 11 parts of perilla, 11 parts of kudzuvine root, 15 parts of cape jasmine fruit, 25 parts of villous amomum fruit, 20 parts of radish seed, 9 parts of astragalus root, 14 parts of cogongrass rhizome, 14 parts of chrysanthemum, 6 parts of boat-fruited sterculia seed, 15 parts of dandelion, 14 parts of reed rhizome, 13 parts of elsholtzia and 25 parts of honeysuckle.
3. The traditional Chinese medicine composition according to claim 2, wherein: the rhizoma Imperatae is fresh rhizoma Imperatae, and rhizoma Phragmitis is fresh rhizoma Phragmitis.
4. The traditional Chinese medicine composition according to any one of claims 1 to 3, characterized in that: the preparation is prepared by taking medicinal powder of the raw materials or water or organic solvent extracts of the raw materials as active ingredients and adding pharmaceutically acceptable auxiliary materials.
5. The traditional Chinese medicine composition according to claim 4, wherein: the preparation is an oral preparation.
6. The traditional Chinese medicine composition according to claim 5, wherein: the oral preparation comprises granules, solutions, pills, powder, paste and tablets.
7. The method for preparing the traditional Chinese medicine composition according to any one of claims 1 to 6, which is characterized in that: it comprises the following steps:
(1) Weighing the raw materials according to the proportion of claim 1;
(2) Grinding the raw materials into powder, or extracting with water or organic solvent, and adding adjuvants or auxiliary components commonly used in medicine.
8. Use of the Chinese medicinal composition according to any one of claims 1 to 5 in the preparation of a medicament for treating cough with fever and sputum.
9. Use according to claim 8, characterized in that: the medicine is a medicine for relieving fever and/or resolving phlegm and relieving cough.
10. Use according to claim 8 or 9, characterized in that: the medicine has effects of eliminating pathogenic factors and strengthening body resistance.
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