CN118045156A - Heat-clearing and healing-promoting lotion and formula and application method thereof - Google Patents
Heat-clearing and healing-promoting lotion and formula and application method thereof Download PDFInfo
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Abstract
The invention relates to the technical field of medicament preparation, in particular to a heat-clearing and healing-promoting lotion and a formula and a using method thereof, wherein the heat-clearing and healing-promoting lotion comprises the following components in parts by mass: 30-60 parts of Chinese brake herb, 30-60 parts of garden burnet root, 15-30 parts of bletilla striata, 15-30 parts of ash bark, 15-30 parts of catechu, 10-20 parts of baked ginger charcoal and 5-10 parts of liquorice; decocting the above materials with water to obtain decoction; is used by means of enema cleaning. After clinical specific use, the invention can reduce the first pass effect generated by oral administration of the medicine, lead the medicine to be in direct contact with intestinal mucosa, improve the local blood concentration of focus, quickly act on lesion sites and directly play the role of anti-inflammatory and sterilizing, thereby better improving the treatment effect of ulcerative colitis.
Description
Technical Field
The invention relates to the technical field of medicament preparation, in particular to a heat-clearing and healing-promoting lotion and a formula and a using method thereof.
Background
The main means for diagnosis of ulcerative colitis are currently based on clinical evaluations, combined with endoscopic, histological, radiological and biochemical indicators. In the aspect of treatment medication, the corresponding selection is mainly carried out according to the following conditions: ① For patients with mild ulcerative colitis, the clinical treatment of the medicine is preferably mesalamine, sulfasalazine, balsalazide and other amino acid salicylic acid salt medicines; ② For patients with severe ulcerative colitis, medicines for relieving symptoms such as corticosteroids are often selected, and sometimes the symptoms can be controlled, but the cure rate is low, and the patients are easy to relapse after stopping the medicines, so that the medicines cannot be used for maintenance treatment; ③ When necessary, the operation treatment is carried out, however, the purpose of radically treating the disease can not be achieved by the operation treatment, and complications possibly generated after the operation, such as anastomotic stoma stenosis, pelvic infection, small intestinal obstruction, ostomy bag inflammation and the like, limit the clinical application range and are difficult to implement comprehensively. Therefore, the medicine lacks a specific medicine with obvious curative effect, convenient use and no toxic or side effect clinically. Therefore, finding effective drugs for treating ulcerative colitis from traditional Chinese medicines is a focus of attention of many pharmaceutical students.
Disclosure of Invention
Therefore, in order to solve the problems, a lotion for clearing heat and promoting healing and a formula and a using method thereof are provided.
In order to achieve the technical effects, the invention is realized by the following technical scheme: the formula of the heat clearing and healing promoting lotion is characterized by comprising the following components in parts by mass: 30-60 parts of Chinese brake herb, 30-60 parts of garden burnet root, 15-30 parts of bletilla striata, 15-30 parts of ash bark, 15-30 parts of catechu, 10-20 parts of baked ginger charcoal and 5-10 parts of liquorice.
Further, the composition comprises the following components in parts by mass: 30 parts of Chinese brake herb, 30 parts of garden burnet, 15 parts of bletilla striata, 15 parts of ash bark, 15 parts of catechu, 10 parts of baked ginger charcoal and 5 parts of liquorice.
The invention further aims at providing a heat-clearing and healing-promoting lotion, which is characterized by comprising the following steps of:
s1.1, taking all the traditional Chinese medicines, and soaking all the traditional Chinese medicines in clear water for 90-120 min;
S1.2, placing the soaked traditional Chinese medicine into a medicine decocting pot, decocting with medium and large fire until boiling, then decocting with small fire until boiling, decocting for 30-45 min, filtering with gauze, pouring out the liquid medicine, and standing at room temperature to obtain a first liquid medicine for later use;
S1.3, adding 400-600 ml of water into the decoction pot again, decocting for 30-40 min again by the same method, filtering with gauze, pouring out the liquid medicine, and standing at room temperature to obtain a second liquid medicine for later use;
s1.4, mixing and uniformly stirring the first liquid medicine and the second liquid medicine to obtain a mixed liquid medicine for later use;
and S5, finally, placing the uniformly mixed liquid medicine in a constant-temperature water bath kettle with the temperature of 38-40 ℃ to carry out concentrated decoction on the liquid medicine to 130-170 ml, then placing the liquid medicine in a storage bottle for sealing and storing, and refrigerating in an environment with the temperature of 3-5 ℃ for standby, thus obtaining the heat clearing and healing promoting lotion.
The invention further aims at providing a use method of the heat clearing and healing promoting lotion, which is characterized by comprising the following steps of:
s1, adding warm boiled water into the lotion, and stirring and mixing uniformly;
S2, placing the mixed medicament into an enema device;
S3, placing the enema equipment into the human body, and then conveying the medicine to the focus position of ulcerative colitis in the patient through an external medicine conveying mechanism of the enema equipment, and carrying out medicated bath cleaning on the focus position.
The beneficial effects of the invention are as follows:
The eight medicines in the formula of the heat-clearing and healing-promoting lotion are monarch medicines, the Chinese brake herb and the garden burnet are monarch medicines, the cortex fraxini and the catechu are ministerial medicines, the pseudo-ginseng and the bletilla striata are adjuvant medicines, the baked ginger charcoal is an anti-adjuvant medicine, and the liquorice is a guiding medicine, and all medicines cooperate to play roles of clearing heat and detoxicating and dredging collaterals, stopping bleeding and relieving diarrhea and activating blood and promoting granulation together; meanwhile, the invention can reduce the first pass effect generated by oral administration of the medicine, so that the medicine directly contacts intestinal mucosa, improves the local blood concentration of focus, rapidly acts on lesion sites, directly plays the role of anti-inflammatory and sterilization, and further better improves the treatment effect of ulcerative colitis.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a flow chart of the preparation of the heat clearing and healing promoting lotion of the invention;
FIG. 2 is a flow chart of a method for using the heat-clearing and healing-promoting lotion.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
Referring to fig. 1, a preparation process of the swelling and pain relieving lotion is shown;
Step one, material preparation: weighing 30 parts of Chinese brake herb, 30 parts of garden burnet root, 15 parts of bletilla striata, 15 parts of ash bark, 15 parts of catechu, 10 parts of baked ginger charcoal and 5 parts of liquorice according to mass parts; preparation equipment (decocting pot or pan), and clear water (purified water);
Step two, preparation of a medicament: soaking 30 parts of selected Chinese brake herb, 30 parts of garden burnet, 15 parts of bletilla striata, 15 parts of ash bark, 15 parts of catechu, 10 parts of baked ginger charcoal and 5 parts of liquorice in clear water for 100min;
Step three, placing the soaked traditional Chinese medicine into a decoction pot, decocting with medium and strong fire until boiling, then decocting with small fire until boiling, decocting for 35min, filtering with gauze, pouring out the liquid medicine, and standing at room temperature to obtain a first liquid medicine for later use;
Adding 500ml of water into the decoction pot again, decocting for 40min by the same method again, filtering with gauze, pouring out the liquid medicine, and standing at room temperature to obtain a second liquid medicine for later use;
step five, mixing and uniformly stirring the first liquid medicine and the second liquid medicine to obtain a mixed liquid medicine for later use;
Step six, finally, placing the uniformly mixed liquid medicine in a constant-temperature water bath kettle at 40 ℃ to carry out thick decoction on the liquid medicine to 160ml, then placing the liquid medicine in a storage bottle for sealing and preservation, and refrigerating in an environment at 4 ℃ for standby; the heat-clearing and healing-promoting lotion is prepared.
When the heat-clearing and healing-promoting lotion prepared by the steps is used, an enema cleaning mode is adopted, and the method specifically comprises the following steps:
s1, taking a certain amount of heat clearing and healing promoting lotion at a time, adding a proper amount of warm boiled water, and then stirring and mixing uniformly;
S2, placing the mixed medicament into an enema device;
S3, placing the enema equipment into the human body, and then conveying the medicine to the focus position of ulcerative colitis in the patient through an external medicine conveying mechanism of the enema equipment, and carrying out medicated bath cleaning on the focus position.
S4, performing enema cleaning for 1 to 2 times a day according to the mode of S1 to S3; or follow the doctor's advice.
Example 2
This example describes the situation after use for a particular patient as follows:
step one: the patient is diagnosed as follows:
Patient Wang Mou, male, 80 years old, is admitted to 2023-07-17 wheelchair for more than 10 years old, more than 2 months old due to "repeated bloody purulent stool". Ulcerative colitis was diagnosed with bleeding. After admission, the related examination such as electrocardiogram, blood routine and the like is perfected. The method is characterized by performing symptomatic treatment such as colon inflammation inhibition, energy supplementation, acid inhibition, stomach protection and the like, monitoring blood pressure and closely observing the stool condition of a patient.
Step two, treatment recovery, specifically as follows:
The patient is admitted on the 2 nd day, the general condition can be that the vital sign is stable, the patient complains about bloody pus and stool 6 times per day, the pus is more, the abdominal pain is sometimes cough, expectoration, sticky phlegm, grey white color, dry mouth, frequent dizziness, tinnitus, hypodynamia, shortness of breath, no palpitation, chest distress and the like, poor sleep and incontinence of urine and feces.
Medical staff sets up therapeutic drugs: 40 parts of Chinese brake herb, 40 parts of garden burnet, 30 parts of bletilla striata, 30 parts of ash bark, 20 parts of catechu, 10 parts of baked ginger charcoal and 10 parts of liquorice; 7 doses, one dose per day, are decocted with water to obtain decoction, and are reserved for clysis for 20min.
The patient is admitted on the 3 rd day, the general condition can be measured, the vital sign is stable, the patient complains about purulent stool for 4 times/day, the purulent stool is reduced forehand, the abdominal pain is relieved, nausea, acid regurgitation, heartburn and the like are avoided, and the patient has cough, expectoration, sticky phlegm, grey white color, dry mouth, common sense dizziness, tinnitus, hypodynamia, shortness of breath, palpitation, chest distress and the like, insomnia and incontinence of urine and feces; continuing traditional Chinese medicine retention enema according to the doctor's advice;
Patient admission day 5, general case can, and it is steady to survey vital sign, patient complains: the bloody pus is better before, the stool is shaped, the times of the stool are reduced before, the times of the stool are 3 times per day, abdominal pain is occasionally caused, the sleep is poor, and urination dropout is forbidden. The traditional Chinese medicine retention enema is continued according to the doctor's advice.
Patient admission, day 11, patient complaint: the purulent blood is obviously relieved, the stool is shaped, mucus is sometimes formed, the frequency is reduced in comparison with the former frequency, the frequency is 2 times daily, no abdominal pain exists, the vital sign measurement is stable, the sleep is poor, and the automatic control can be realized. The traditional Chinese medicine retention enema is continued according to the doctor's advice.
In conclusion, compared with the traditional Chinese medicine symptom improvement condition before and after treatment of patients, the heat-clearing and healing-promoting lotion is used for observing the change condition of enteroscopy and serum inflammatory factors, and comparing the difference before and after treatment can obtain the effect of the heat-clearing and healing-promoting lotion on treating ulcerative colitis toxin damage intestinal collaterals, has obvious curative effects on relieving symptoms and improving intestinal mucosa inflammation degree, can further develop and prevent and delay the occurrence of diseases, and has definite effect and obvious curative effect.
Claims (4)
1. The formula of the heat clearing and healing promoting lotion is characterized by comprising the following components in parts by mass: 30-60 parts of Chinese brake herb, 30-60 parts of garden burnet root, 15-30 parts of bletilla striata, 15-30 parts of ash bark, 15-30 parts of catechu, 10-20 parts of baked ginger charcoal and 5-10 parts of liquorice.
2. The formula of the heat-clearing and healing-promoting lotion according to claim 1, which is characterized by comprising the following components in parts by mass: 30 parts of Chinese brake herb, 30 parts of garden burnet, 15 parts of bletilla striata, 15 parts of ash bark, 15 parts of catechu, 10 parts of baked ginger charcoal and 5 parts of liquorice.
3. The heat clearing and healing promoting lotion according to claim 1, wherein the preparation comprises the following steps:
s1.1, taking all the traditional Chinese medicines in the claims 1 or 2, and soaking all the traditional Chinese medicines in clear water for 90-120 min;
S1.2, placing the soaked traditional Chinese medicine into a medicine decocting pot, decocting with medium and large fire until boiling, then decocting with small fire until boiling, decocting for 30-45 min, filtering with gauze, pouring out the liquid medicine, and standing at room temperature to obtain a first liquid medicine for later use;
S1.3, adding 400-600 ml of water into the decoction pot again, decocting for 30-40 min again by the same method, filtering with gauze, pouring out the liquid medicine, and standing at room temperature to obtain a second liquid medicine for later use;
s1.4, mixing and uniformly stirring the first liquid medicine and the second liquid medicine to obtain a mixed liquid medicine for later use;
S1.5, finally placing the uniformly mixed liquid medicine in a constant-temperature water bath kettle with the temperature of 38-40 ℃ to carry out concentrated decoction on the liquid medicine to 130-170 ml, then placing the liquid medicine in a storage bottle for sealing and storing, and refrigerating in an environment with the temperature of 3-5 ℃ for standby; the heat-clearing and healing-promoting lotion is prepared.
4. A method of using a swelling and pain relieving lotion according to claim 3, comprising the steps of:
s2.1, adding the lotion into warm boiled water, and stirring and mixing uniformly;
s2.2, placing the mixed medicament into an enema device;
s2.3, placing the enema equipment into a patient body at the end of the human body, then conveying the medicine to the focus position of ulcerative colitis in the patient body through an external medicine conveying mechanism of the enema equipment, and carrying out medicated bath cleaning on the focus position;
s2.4, performing enema cleaning for 1 to 2 times a day according to the mode of S1 to S3; or follow the doctor's advice.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410184997.4A CN118045156A (en) | 2024-02-19 | 2024-02-19 | Heat-clearing and healing-promoting lotion and formula and application method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202410184997.4A CN118045156A (en) | 2024-02-19 | 2024-02-19 | Heat-clearing and healing-promoting lotion and formula and application method thereof |
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