CN102671091A - Medicine composition for preventing surgical postoperative uroschesis - Google Patents
Medicine composition for preventing surgical postoperative uroschesis Download PDFInfo
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- CN102671091A CN102671091A CN2012101698539A CN201210169853A CN102671091A CN 102671091 A CN102671091 A CN 102671091A CN 2012101698539 A CN2012101698539 A CN 2012101698539A CN 201210169853 A CN201210169853 A CN 201210169853A CN 102671091 A CN102671091 A CN 102671091A
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- uroschesis
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Abstract
The invention discloses a medicine composition for preventing surgical postoperative uroschesis. The medicine composition is characterized in that raw material medicine consists of aralis tengyuch euonymus bark, cowherb seed, resurrection lily rhizome, saponin, fistular onion stalk, almond, mother chrysanthemum, elecampane, borneol and peach gum. Clinical study results show that the medicine composition can reduce the occurrence rate of the surgical postoperative uroschesis, the urination condition of patients is effectively relieved, the safety performance is good, the operation is simple and convenient, the painlessness is realized, and the medicine composition can be easily accepted by patients.
Description
[technical field]
The present invention relates to the field of Chinese medicines, be specifically related to treat a kind of pharmaceutical composition that is used for the prevention of surgical postoperative urine retention.
[background technology]
The surgical postoperative urine retention is the abdominal surgery most common complication; Polyphyly anesthesia reaction inhibition micturition reflex or abdominal muscular relaxation, bladder muscle Tension Difference; Pressure to inside increases is insensitive; The incision pain reflexive causes that sphincter of urethra spasm and uncomfortable urinates in bed, due to the reasons such as tearing wound of being afraid of firmly to urinate.Especially for the elderly men patient, possibly cause that the incidence rate of urine retention more is higher than general patient because of recessiveness or dominance prostate hyperplasia.In case urine retention fails in time to get rid of, expansion of the bladder is of a specified duration excessively, and muscle loses contractility, then is difficult in a short time recovering, and brings adverse consequences to the patient.The normal employing of the method for traditional treatment urine retention listened a singing of the stream, hot compress, massage hypogastric region induced uresis, also adopts intramuscular injection neostigmine method, invalid after, finally need urethral catheterization.And indwelling catheter can cause suffering and inconvenience to the patient, also can increase the chance of urinary tract infection.
[summary of the invention]
Technical assignment of the present invention is the deficiency to above prior art, provides a kind of curative effect certainly, can be used for the pharmaceutical composition of prevention of surgical postoperative urine retention.
The technical scheme that the present invention solves its technical problem is: a kind of pharmaceutical composition that is used for the prevention of surgical postoperative urine retention is characterized in that processing 14 ~ 20 parts of: Cortex araliae chinensis by following materials of weight proportions medicine 10 ~ 16 parts of Semen Vaccariae; 10 ~ 16 parts of Rhizoma Kaempferiae, 10 ~ 16 parts of Fructus Gleditsia, very light blue 10 ~ 16 parts; 6 ~ 10 parts in Semen Armeniacae Amarum, 14 ~ 20 parts of Flos Chrysanthemi Indicis, 14 ~ 20 parts of Radix Inulaes; 1 ~ 2 part of Borneolum Syntheticum, 3 ~ 5 parts of gumshiraz.
It optimizes weight proportion is 16 parts of: Cortex araliae chinensis, 12 parts of Semen Vaccariae, 12 parts of Rhizoma Kaempferiae, 12 parts of Fructus Gleditsia, very light blue 12 parts, 8 parts in Semen Armeniacae Amarum, 16 parts of Flos Chrysanthemi Indicis, 16 parts of Radix Inulaes, 1 part of Borneolum Syntheticum, 4 parts of gumshiraz.
Wherein said:
Cortex araliae chinensis adds the phloem of the Zhi Wu of section Cortex araliae chinensis for Wu.Warm in nature, it is little salty to distinguish the flavor of.Go into liver, the heart, kidney three warps.Have and be good for the stomach, convergence, diuresis and sugaring effect.
Semen Vaccariae is the seed of pinkwort Vaccaria segetalis.Hardship, flat.Return liver, stomach warp.Promoting blood circulation to restore menstrual flow, the stimulating milk secretion detumescence.
Rhizoma Kaempferiae is the dry rhizome of zingiberaceous plant Rhizoma Kaempferiae.Nature and flavor are hot, temperature.Return the stomach warp.In the feasible temperature of merit, help digestion pain relieving.
Fructus Gleditsia is the dry Fructus Gleditsia of leguminous plant.Nature and flavor are hot, temperature.Return liver, stomach warp.The merit poison holding of can subsiding a swelling, evacuation of pus, parasite killing.
Very light blue, be the cauloid of Liliaceae allium Herba Alii fistulosi, merit can be delivered and activate yang, the detoxifcation parasite killing.
Semen Armeniacae Amarum is the seed of rosaceous plant Fructus Pruni, wild apricot, Prunus armeniaca L.var.ansu Maxim., prunus mandshuricaKoehne, but the merit lung qi dispersing, loosening bowel to relieve constipation.
Flos Chrysanthemi Indici is the head inflorescence of Compositae herbaceos perennial Herba Dendranthematis indici, but the merit heat-clearing and toxic substances removing, detumescence.
Radix Inulae is the dry root of feverfew Radix Inulae or Radix Inulae.Nature and flavor are hot, bitter, temperature.Return liver, spleen channel.But the merit invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, pain relieving is antiabortive.
Borneolum Syntheticum is the processed goods of Dipterocarpaceae plant Borneolum Syntheticum resin, or is that Camphora, Lignum Pini Nodi wet goods are with the synthetic article of being processed into of chemical method.Nature and flavor are hot, bitter, are slightly cold.GUIXIN, spleen, lung meridian.The merit refreshment of can having one's ideas straightened out, clearing away heat to alleviate pain.
Gumshiraz is gone up effusive resin for the rosaceous plant peach tree does, and is water-soluble gum.But the merit removing heat from blood and promoting blood circulation, benefiting qi for promoting granulation.
Composition principle: the surgical postoperative urine retention is meant that the surgical postoperative intravesical is full of urine and can not discharges, and primary disease belongs to the traditional Chinese medical science " difficulty in urination ", " stranguria with turbid discharge " category.Its major lesions is controlled and should be transferred smooth three warmers mechanism of qi, tonneau bladder at bladder.Cortex araliae chinensis can play diuresis; The Semen Vaccariae promoting blood circulation to restore menstrual flow, Rhizoma Kaempferiae circulation of qi promoting warming middle-JIAO is controlled from vim and vigour respectively; Fructus Gleditsia detumescence poison holding, very light blue activating yang, Semen Armeniacae Amarum a surname send out, the unobstructed yang-energy of this three; The Flos Chrysanthemi Indici heat-clearing and toxic substances removing; The Radix Inulae promoting the flow of QI for relieving the stagnancy; Borneolum Syntheticum increases transdermal absorption factor; Gumshiraz removing heat from blood and promoting blood circulation and can increase local adhesive ability.
In sum, these article compound basis Chinese herb decoction opinion is administered opinion and the result of study cooperation of combination modern medicine and pharmacology and is got, and plays logical urinary bladder channel yang-energy altogether; The heat clearing away of invigorating blood circulation, the effect of diuresis resolving depression, thus can reduce the incidence rate of surgical postoperative urine retention; Effectively improve patient's the situation of urinating, safety is good, and is easy and simple to handle; Painless, the patient is easy to accept.
[specific embodiment]
Below in conjunction with practical situation, specific embodiments of the invention elaborates.
Embodiment 1,14 parts of crude drug weight proportion: Cortex araliae chinensis, 10 parts of Semen Vaccariae, 10 parts of Rhizoma Kaempferiae, 10 parts of Fructus Gleditsia, very light blue 10 parts, 6 parts in Semen Armeniacae Amarum, 14 parts of Flos Chrysanthemi Indicis, 14 parts of Radix Inulaes, 1 part of Borneolum Syntheticum, 3 parts of gumshiraz.
Method for preparing is following: get broken mistake 100 mesh sieves of above-mentioned raw materials medicated powder, mix homogeneously during use, adds 60 ℃ of hot water, stir thick paste shape product.
Embodiment 2,20 parts of crude drug weight proportion: Cortex araliae chinensis, 16 parts of Semen Vaccariae, 16 parts of Rhizoma Kaempferiae, 16 parts of Fructus Gleditsia, very light blue 16 parts, 10 parts in Semen Armeniacae Amarum, 20 parts of Flos Chrysanthemi Indicis, 20 parts of Radix Inulaes, 2 parts of Borneolum Syntheticums, 5 parts of gumshiraz.
The following: Qu of method for preparing Cortex araliae chinensis, Semen Vaccariae, Rhizoma Kaempferiae, Fructus Gleditsia, very light blue, Semen Armeniacae Amarum, Flos Chrysanthemi Indici, Radix Inulae decoct twice, each 0.5 hour, boil liquid and filter; Boil the gumshiraz coarse powder that adds in the liquid after pulverizing; Heat 80 ℃ and melt fully to gumshiraz, be concentrated into relative density 1.20 ~ 1.25, add the Borneolum Syntheticum after pulverizing when temperature is reduced to 40 ℃; And stir, get thick paste shape product.
Embodiment 3,16 parts of crude drug weight proportion: Cortex araliae chinensis, 12 parts of Semen Vaccariae, 12 parts of Rhizoma Kaempferiae, 12 parts of Fructus Gleditsia, very light blue 12 parts, 8 parts in Semen Armeniacae Amarum, 16 parts of Flos Chrysanthemi Indicis, 16 parts of Radix Inulaes, 1 part of Borneolum Syntheticum, 4 parts of gumshiraz.Method for preparing such as embodiment 1.
Embodiment 4,16 parts of crude drug weight proportion: Cortex araliae chinensis, 12 parts of Semen Vaccariae, 12 parts of Rhizoma Kaempferiae, 12 parts of Fructus Gleditsia, very light blue 12 parts, 8 parts in Semen Armeniacae Amarum, 16 parts of Flos Chrysanthemi Indicis, 16 parts of Radix Inulaes, 1 part of Borneolum Syntheticum, 4 parts of gumshiraz.Method for preparing such as embodiment 2.
The method for using of embodiment 1 ~ 4 is: get 30 ~ 40 gram gained thick pastes, fill up umbilical opening and around, gauze soaked in hot water wrings out, spread on umbilical part, the insulation of loam cake hot water bag, each 1 hour, 2 times on the one after folding.
The present invention can effectively reach and improve surgical postoperative urine retention symptom, and side effect is less.The above results is that clinical data proves that fully interrelated data is following, wherein studies drug use and is the crude drug weight proportion among the embodiment 4.
1 object and method
1.1 object: be in January, 2010 ~ 2010 year December inpatient 120 examples in my institute's anorectal disease postoperative urine retention, be divided into two groups at random, 60 examples are organized in treatment, male 44 examples, women 16 examples, 34～62 years old age, average (43.6 ± 6.7) year.Matched group 60 examples, male 46 examples, women 14 examples, 33～63 years old age, average (45.6 ± 7.4) year.Two groups of ages, sex, mixed hemorrhoid are by stages, consuming time, the operative incision number of operation etc. is through statistical procedures, and difference there are no significant meaning (P>0.05), have comparability.
1.2 method:
1.2.1 research method: treatment group application implementation example 4 gained pharmaceutical compositions, method for using are for getting 30 ~ 40 gram gained thick pastes, fill up around umbilical opening reaches; Gauze soaked in hot water wring out, spread on umbilical part, the insulation of loam cake hot water bag after folding; Each 1 hour, 2 times on the one.The conventional intramuscular injection neostigmine of matched group medicinal liquid 2ml.
1.2.2 voluntary micturition patient's urination time first, postoperative 10 hours total volume of urine of voided volume, postoperative, the postoperative >=10 routine number that (being urine retention) take place of hour not urinating yet first in the observation index record 10 hours.
1.2.3 statistical analysis adopts SPSS16.0 to set up data base's line data analysis of going forward side by side.Measurement data adopts the t check; Enumeration data adopts X 2 test.< 0.05 expression has the significance meaning to P.
2 results
2.1 in two groups of postoperatives 10 hours urine retention a situation arises relatively: urine retention incidence rate treatment group is 10.0% in two groups of patient's postoperatives 10 hours, matched group be 28.3%, two group of urine retention incidence rate relatively, difference has significance meaning (P < 0.05).
2.2 urination time is relatively first for two groups of postoperative voluntary micturition patients: two groups of postoperative voluntary micturition patient's numbers and the group of urination time treatment first are 54 examples, (6.34 ± 0.17) hour; Matched group is 43 examples, (9.56 ± 0.36) hour; Two groups relatively, and difference has highly significant property meaning (P < 0.01).
2.3 two groups of postoperative voluntary micturition patient voided volume, postoperative total volume of urine comparisons in 10 hours first: see the following form.Two groups of postoperatives first voided volume relatively, difference has highly significant property meaning (P < 0.01); 10 hours total volume of urine of two groups of postoperatives relatively, difference has highly significant property meaning (P < 0.01).
Table two group postoperative voluntary micturition patient voided volume, 10 hours total volume of urine of postoperative first compares (ml)
| n | Voided volume first | 10 hours total volume of urine of postoperative | |
| The treatment group | 54 | 130.00±25.22 | 977.89±104.12 |
| Matched group | 43 | 56.14±14.36 | 746.48±83.69 |
2.4 untoward reaction patient's vital sign (blood pressure, heart rate, body temperature, breathing), physical examination, blood biochemical analysis, electrocardiogram and routine urinalysis Non Apparent Abnormality during treating.
3. conclusion: the prompting of this result of study, the present invention is not only being played a role aspect the generation of prevention of postoperative urine retention, and has certain effect promoting postoperative patient to urinate as early as possible, and the untoward reaction that occurs is few.
Claims (2)
1. a pharmaceutical composition that is used for the prevention of surgical postoperative urine retention is characterized in that being processed by following materials of weight proportions medicine: 14 ~ 20 parts of Cortex araliae chinensis, 10 ~ 16 parts of Semen Vaccariae; 10 ~ 16 parts of Rhizoma Kaempferiae, 10 ~ 16 parts of Fructus Gleditsia, very light blue 10 ~ 16 parts; 6 ~ 10 parts in Semen Armeniacae Amarum, 14 ~ 20 parts of Flos Chrysanthemi Indicis, 14 ~ 20 parts of Radix Inulaes; 1 ~ 2 part of Borneolum Syntheticum, 3 ~ 5 parts of gumshiraz.
2. a kind of pharmaceutical composition that is used for the prevention of surgical postoperative urine retention according to claim 1 is characterized in that processing 16 parts of: Cortex araliae chinensis by following materials of weight proportions medicine 12 parts of Semen Vaccariae; 12 parts of Rhizoma Kaempferiae, 12 parts of Fructus Gleditsia, very light blue 12 parts; 8 parts in Semen Armeniacae Amarum, 16 parts of Flos Chrysanthemi Indicis, 16 parts of Radix Inulaes; 1 part of Borneolum Syntheticum, 4 parts of gumshiraz.
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| CN2012101698539A CN102671091B (en) | 2012-05-28 | 2012-05-28 | Medicine composition for preventing surgical postoperative uroschesis |
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| CN2012101698539A CN102671091B (en) | 2012-05-28 | 2012-05-28 | Medicine composition for preventing surgical postoperative uroschesis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341108A (en) * | 2013-07-01 | 2013-10-09 | 王海水 | Pharmaceutical composite for treating stress urinary incontinence after prostatectomy |
| CN104547594A (en) * | 2015-01-29 | 2015-04-29 | 陈柍汛 | Traditional Chinese medicine for treating qi stagnation type urinary retention after abdominal operation |
| CN105288179A (en) * | 2015-10-13 | 2016-02-03 | 陈希云 | Traditional Chinese medicine hot-compress agent for treating postoperative urinary retention of mixed hemorrhoid and nursing method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102228603A (en) * | 2011-06-16 | 2011-11-02 | 莫忆鸣 | Chinese medicine for treating retention of urine |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102228603A (en) * | 2011-06-16 | 2011-11-02 | 莫忆鸣 | Chinese medicine for treating retention of urine |
Non-Patent Citations (2)
| Title |
|---|
| 宁在芳: "坐浴治疗妇科病", 《医药与保健》 * |
| 秦臻: "癃闭的古代中药外治法探析", 《遵义医学院学报》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341108A (en) * | 2013-07-01 | 2013-10-09 | 王海水 | Pharmaceutical composite for treating stress urinary incontinence after prostatectomy |
| CN104547594A (en) * | 2015-01-29 | 2015-04-29 | 陈柍汛 | Traditional Chinese medicine for treating qi stagnation type urinary retention after abdominal operation |
| CN105288179A (en) * | 2015-10-13 | 2016-02-03 | 陈希云 | Traditional Chinese medicine hot-compress agent for treating postoperative urinary retention of mixed hemorrhoid and nursing method |
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| CN102671091B (en) | 2013-12-04 |
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Granted publication date: 20131204 Termination date: 20140528 |