CN117916371A - 用于加工的装置、系统和方法 - Google Patents

用于加工的装置、系统和方法 Download PDF

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Publication number
CN117916371A
CN117916371A CN202280052362.8A CN202280052362A CN117916371A CN 117916371 A CN117916371 A CN 117916371A CN 202280052362 A CN202280052362 A CN 202280052362A CN 117916371 A CN117916371 A CN 117916371A
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CN
China
Prior art keywords
reservoir
filter
fluid
inlet port
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN202280052362.8A
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English (en)
Chinese (zh)
Inventor
图斯哈尔·甘迪·米斯拉
奥尔加·塞尔策
丹尼尔·P·西尼科拉
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Flagship Venture & Innovation No6 Co ltd
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Flagship Venture & Innovation No6 Co ltd
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Application filed by Flagship Venture & Innovation No6 Co ltd filed Critical Flagship Venture & Innovation No6 Co ltd
Publication of CN117916371A publication Critical patent/CN117916371A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
  • Filtration Of Liquid (AREA)
CN202280052362.8A 2021-07-27 2022-07-27 用于加工的装置、系统和方法 Pending CN117916371A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163203638P 2021-07-27 2021-07-27
US63/203,638 2021-07-27
PCT/US2022/038427 WO2023009568A1 (en) 2021-07-27 2022-07-27 Devices systems and methods for processing

Publications (1)

Publication Number Publication Date
CN117916371A true CN117916371A (zh) 2024-04-19

Family

ID=82899110

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280052362.8A Pending CN117916371A (zh) 2021-07-27 2022-07-27 用于加工的装置、系统和方法

Country Status (7)

Country Link
US (1) US20250002898A1 (https=)
EP (1) EP4377454A1 (https=)
JP (1) JP2024528875A (https=)
KR (1) KR20240047986A (https=)
CN (1) CN117916371A (https=)
AU (1) AU2022318881A1 (https=)
WO (1) WO2023009568A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230203192A1 (en) * 2020-05-20 2023-06-29 Flagship Pioneering, Inc. Compositions and methods for producing human polyclonal antibodies
MX2024003262A (es) 2021-09-17 2024-06-19 Flagship Pioneering Innovations Vi Llc Composiciones y metodos para producir poliribonucleotidos circulares.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030064951A1 (en) * 1998-11-12 2003-04-03 Valentis, Inc. Methods for purifying nucleic acids
WO2015034925A1 (en) 2013-09-03 2015-03-12 Moderna Therapeutics, Inc. Circular polynucleotides
US10407683B2 (en) 2014-07-16 2019-09-10 Modernatx, Inc. Circular polynucleotides
EP4660315A3 (en) * 2015-05-29 2026-03-18 CureVac Manufacturing GmbH A method for producing and purifying rna, comprising at least one step of tangential flow filtration
EP4219532A3 (en) 2015-06-05 2023-08-16 Dana-Farber Cancer Institute, Inc. Compositions and methods for transient gene therapy with enhanced stability
WO2017222911A1 (en) 2016-06-20 2017-12-28 The Board Of Trustees Of The Leland Stanford Junior University Circular rnas and their use in immunomodulation
AU2018251187B2 (en) 2017-04-14 2024-03-28 Dana-Farber Cancer Institute, Inc. Compositions and methods for transient gene therapy with enhanced stability
CN111819185A (zh) 2017-12-15 2020-10-23 旗舰创业创新第六有限责任公司 包含环状多核糖核苷酸的组合物及其用途
CN112399860B (zh) 2018-06-06 2024-08-16 麻省理工学院 用于在真核细胞中翻译的环状rna
WO2020023655A1 (en) 2018-07-24 2020-01-30 Flagship Pioneering, Inc. Compositions comprising circular polyribonucleotides and uses thereof
AU2019310448A1 (en) 2018-07-24 2021-03-11 Mayo Foundation For Medical Education And Research Circularized engineered rna and methods
WO2020160087A1 (en) * 2019-01-29 2020-08-06 Flagship Pioneering Innovations V, Inc. Methods of separating long polynucleotides from a composition
US20220143062A1 (en) 2019-03-04 2022-05-12 Flagship Pioneering Innovations Vi, Llc Circular polyribonucleotides and pharmaceutical compositions thereof
BR112021023411A2 (pt) 2019-05-22 2022-02-01 Massachusetts Inst Technology Composições e métodos de rna circular
US20220288176A1 (en) 2019-08-28 2022-09-15 The Board Of Trustees Of The Leland Stanford Junior University Circular rna modification and methods of use

Also Published As

Publication number Publication date
JP2024528875A (ja) 2024-08-01
AU2022318881A1 (en) 2024-02-08
KR20240047986A (ko) 2024-04-12
WO2023009568A8 (en) 2023-03-23
WO2023009568A1 (en) 2023-02-02
EP4377454A1 (en) 2024-06-05
US20250002898A1 (en) 2025-01-02

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