CN117916251A - 化合物、化合物的盐、抗体修饰试剂、修饰抗体的制造方法及修饰抗体 - Google Patents

化合物、化合物的盐、抗体修饰试剂、修饰抗体的制造方法及修饰抗体 Download PDF

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Publication number
CN117916251A
CN117916251A CN202280060866.4A CN202280060866A CN117916251A CN 117916251 A CN117916251 A CN 117916251A CN 202280060866 A CN202280060866 A CN 202280060866A CN 117916251 A CN117916251 A CN 117916251A
Authority
CN
China
Prior art keywords
igg
compound
group
salt
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280060866.4A
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English (en)
Chinese (zh)
Inventor
伊东祐二
吉矢拓
津田修吾
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shengpeptide Research Institute Co ltd
Kagoshima University NUC
Original Assignee
Shengpeptide Research Institute Co ltd
Kagoshima University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shengpeptide Research Institute Co ltd, Kagoshima University NUC filed Critical Shengpeptide Research Institute Co ltd
Publication of CN117916251A publication Critical patent/CN117916251A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
CN202280060866.4A 2021-09-08 2022-09-08 化合物、化合物的盐、抗体修饰试剂、修饰抗体的制造方法及修饰抗体 Pending CN117916251A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021146504 2021-09-08
JP2021-146504 2021-09-08
PCT/JP2022/033713 WO2023038082A1 (ja) 2021-09-08 2022-09-08 化合物、化合物の塩、抗体修飾試薬、修飾抗体の製造方法及び修飾抗体

Publications (1)

Publication Number Publication Date
CN117916251A true CN117916251A (zh) 2024-04-19

Family

ID=85506405

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280060866.4A Pending CN117916251A (zh) 2021-09-08 2022-09-08 化合物、化合物的盐、抗体修饰试剂、修饰抗体的制造方法及修饰抗体

Country Status (9)

Country Link
US (1) US20250304617A1 (https=)
EP (1) EP4400509A1 (https=)
JP (1) JPWO2023038082A1 (https=)
KR (1) KR20240052833A (https=)
CN (1) CN117916251A (https=)
AU (1) AU2022342928A1 (https=)
CA (1) CA3231257A1 (https=)
TW (1) TW202328163A (https=)
WO (1) WO2023038082A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026058917A1 (ja) * 2024-09-10 2026-03-19 味の素株式会社 抗体親和性物質を含む化合物、修飾抗体およびそれらの塩ならびに抗体誘導体または抗体－機能性物質コンジュゲートの製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008054030A1 (fr) 2006-11-02 2008-05-08 Kagoshima University Peptide liant l'igg
JP5994068B2 (ja) 2011-08-24 2016-09-21 国立大学法人 鹿児島大学 ＩｇＧ結合性ペプチド及びそれによるＩｇＧの検出および精製方法
ES3058443T3 (es) 2015-05-20 2026-03-10 Univ Kagoshima Modificación específica de anticuerpo con péptido de unión a IgG
DK3470418T3 (da) 2016-06-13 2024-09-30 Univ Kagoshima Site-specifik radioisotop-mærket antistof ved brug af using iggbindende peptid
AU2018259856B2 (en) 2017-04-28 2025-05-01 Ajinomoto Co., Inc. Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof
JP7291395B2 (ja) 2017-06-16 2023-06-15 国立大学法人 鹿児島大学 ＩｇＧ結合ペプチド、及び該ペプチドによる抗体の特異的修飾
TWI886164B (zh) * 2019-10-24 2025-06-11 國立大學法人鹿兒島大學 1價ccap生成物之製造方法
JP7461180B2 (ja) 2020-03-16 2024-04-03 五洋建設株式会社 プレキャスト部材の鉄筋挿入孔の形成方法、プレキャスト部材の接合方法およびプレキャスト部材の製造方法

Also Published As

Publication number Publication date
EP4400509A1 (en) 2024-07-17
US20250304617A1 (en) 2025-10-02
AU2022342928A1 (en) 2024-03-28
JPWO2023038082A1 (https=) 2023-03-16
WO2023038082A1 (ja) 2023-03-16
CA3231257A1 (en) 2023-03-16
TW202328163A (zh) 2023-07-16
KR20240052833A (ko) 2024-04-23

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