TW202328163A - 化合物、化合物之鹽、抗體修飾試劑、修飾抗體之製造方法及修飾抗體 - Google Patents

化合物、化合物之鹽、抗體修飾試劑、修飾抗體之製造方法及修飾抗體 Download PDF

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Publication number
TW202328163A
TW202328163A TW111134182A TW111134182A TW202328163A TW 202328163 A TW202328163 A TW 202328163A TW 111134182 A TW111134182 A TW 111134182A TW 111134182 A TW111134182 A TW 111134182A TW 202328163 A TW202328163 A TW 202328163A
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TW
Taiwan
Prior art keywords
igg
compound
group
formula
salt
Prior art date
Application number
TW111134182A
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English (en)
Chinese (zh)
Inventor
伊東祐二
吉矢拓
津田修吾
Original Assignee
國立大學法人鹿兒島大學
日商胜肽研究所股份有限公司
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Application filed by 國立大學法人鹿兒島大學, 日商胜肽研究所股份有限公司 filed Critical 國立大學法人鹿兒島大學
Publication of TW202328163A publication Critical patent/TW202328163A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
TW111134182A 2021-09-08 2022-09-08 化合物、化合物之鹽、抗體修飾試劑、修飾抗體之製造方法及修飾抗體 TW202328163A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021146504 2021-09-08
JP2021-146504 2021-09-08

Publications (1)

Publication Number Publication Date
TW202328163A true TW202328163A (zh) 2023-07-16

Family

ID=85506405

Family Applications (1)

Application Number Title Priority Date Filing Date
TW111134182A TW202328163A (zh) 2021-09-08 2022-09-08 化合物、化合物之鹽、抗體修飾試劑、修飾抗體之製造方法及修飾抗體

Country Status (9)

Country Link
US (1) US20250304617A1 (https=)
EP (1) EP4400509A1 (https=)
JP (1) JPWO2023038082A1 (https=)
KR (1) KR20240052833A (https=)
CN (1) CN117916251A (https=)
AU (1) AU2022342928A1 (https=)
CA (1) CA3231257A1 (https=)
TW (1) TW202328163A (https=)
WO (1) WO2023038082A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026058917A1 (ja) * 2024-09-10 2026-03-19 味の素株式会社 抗体親和性物質を含む化合物、修飾抗体およびそれらの塩ならびに抗体誘導体または抗体－機能性物質コンジュゲートの製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008054030A1 (fr) 2006-11-02 2008-05-08 Kagoshima University Peptide liant l'igg
JP5994068B2 (ja) 2011-08-24 2016-09-21 国立大学法人 鹿児島大学 ＩｇＧ結合性ペプチド及びそれによるＩｇＧの検出および精製方法
ES3058443T3 (es) 2015-05-20 2026-03-10 Univ Kagoshima Modificación específica de anticuerpo con péptido de unión a IgG
DK3470418T3 (da) 2016-06-13 2024-09-30 Univ Kagoshima Site-specifik radioisotop-mærket antistof ved brug af using iggbindende peptid
AU2018259856B2 (en) 2017-04-28 2025-05-01 Ajinomoto Co., Inc. Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof
JP7291395B2 (ja) 2017-06-16 2023-06-15 国立大学法人 鹿児島大学 ＩｇＧ結合ペプチド、及び該ペプチドによる抗体の特異的修飾
TWI886164B (zh) * 2019-10-24 2025-06-11 國立大學法人鹿兒島大學 1價ccap生成物之製造方法
JP7461180B2 (ja) 2020-03-16 2024-04-03 五洋建設株式会社 プレキャスト部材の鉄筋挿入孔の形成方法、プレキャスト部材の接合方法およびプレキャスト部材の製造方法

Also Published As

Publication number Publication date
EP4400509A1 (en) 2024-07-17
US20250304617A1 (en) 2025-10-02
AU2022342928A1 (en) 2024-03-28
JPWO2023038082A1 (https=) 2023-03-16
WO2023038082A1 (ja) 2023-03-16
CA3231257A1 (en) 2023-03-16
CN117916251A (zh) 2024-04-19
KR20240052833A (ko) 2024-04-23

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