CN117915932A - 通用受体免疫细胞疗法 - Google Patents

通用受体免疫细胞疗法 Download PDF

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Publication number
CN117915932A
CN117915932A CN202280058322.4A CN202280058322A CN117915932A CN 117915932 A CN117915932 A CN 117915932A CN 202280058322 A CN202280058322 A CN 202280058322A CN 117915932 A CN117915932 A CN 117915932A
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cells
molecule
subject
days
cell
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CN202280058322.4A
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Chinese (zh)
Inventor
S·L·亚托米-克拉克
R·利姆
P·K·达西
D·A·谢利
K·瑟克
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Foresight Therapy Co ltd
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Foresight Therapy Co ltd
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Priority claimed from AU2021902320A external-priority patent/AU2021902320A0/en
Application filed by Foresight Therapy Co ltd filed Critical Foresight Therapy Co ltd
Publication of CN117915932A publication Critical patent/CN117915932A/zh
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • C—CHEMISTRY; METALLURGY
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
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CN202280058322.4A 2021-07-28 2022-07-28 通用受体免疫细胞疗法 Pending CN117915932A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2021902320A AU2021902320A0 (en) 2021-07-28 Universal receptor immune cell therapy
AU2021902320 2021-07-28
PCT/AU2022/050795 WO2023004461A1 (en) 2021-07-28 2022-07-28 Universal receptor immune cell therapy

Publications (1)

Publication Number Publication Date
CN117915932A true CN117915932A (zh) 2024-04-19

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Application Number Title Priority Date Filing Date
CN202280058322.4A Pending CN117915932A (zh) 2021-07-28 2022-07-28 通用受体免疫细胞疗法

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US (1) US20240366665A1 (https=)
EP (1) EP4376855A4 (https=)
JP (1) JP2024527963A (https=)
KR (1) KR20240043774A (https=)
CN (1) CN117915932A (https=)
AU (1) AU2022316596A1 (https=)
CA (1) CA3227128A1 (https=)
IL (1) IL310386A (https=)
WO (1) WO2023004461A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9233125B2 (en) * 2010-12-14 2016-01-12 University Of Maryland, Baltimore Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer
US11377481B2 (en) * 2015-12-22 2022-07-05 The Trustees Of The University Of Pennsylvania SpyCatcher and SpyTag: universal immune receptors for T cells
EP3529268B1 (en) * 2016-10-19 2025-02-26 The Scripps Research Institute Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
CA3055200A1 (en) * 2017-03-03 2018-09-07 Obsidian Therapeutics, Inc. Compositions and methods for immunotherapy
EP4588483A3 (en) * 2018-10-03 2025-09-24 University of Pittsburgh- Of the Commonwealth System of Higher Education Covalent adaptor synnotch and chimeric antigen receptors (cars) for programmable antigen-targeting
US20210107969A1 (en) * 2019-07-09 2021-04-15 The Johns Hopkins University Molecules, compositions and methods for treatment of cancer
CN115397439A (zh) * 2020-01-24 2022-11-25 宾夕法尼亚大学理事会 表达通用免疫受体的工程化细胞活性的定量控制

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KR20240043774A (ko) 2024-04-03
AU2022316596A1 (en) 2024-02-15
WO2023004461A1 (en) 2023-02-02
EP4376855A4 (en) 2025-10-15
JP2024527963A (ja) 2024-07-26
IL310386A (en) 2024-03-01
US20240366665A1 (en) 2024-11-07
EP4376855A1 (en) 2024-06-05
CA3227128A1 (en) 2023-02-02

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