JP2024527963A - ユニバーサル受容体免疫細胞療法 - Google Patents

ユニバーサル受容体免疫細胞療法 Download PDF

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JP2024527963A
JP2024527963A JP2024504944A JP2024504944A JP2024527963A JP 2024527963 A JP2024527963 A JP 2024527963A JP 2024504944 A JP2024504944 A JP 2024504944A JP 2024504944 A JP2024504944 A JP 2024504944A JP 2024527963 A JP2024527963 A JP 2024527963A
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JP2024527963A5 (https=
Inventor
エル. ヤトミ-クラーク,スティーブン
リム,レベッカ
ケー. ダーシー,フィリップ
エイ. シェリー,ダニエル
セク,ケビン
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プレシャント セラピューティクス リミテッド
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    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31Chimeric antigen receptors [CAR]
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70521CD28, CD152
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/15Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
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    • A61K40/4203Receptors for growth factors
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    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
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    • A61K40/42Cancer antigens
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    • A61K40/4214Receptors for cytokines
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    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • C07K16/2851Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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    • A61K2239/23On/off switch
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    • A61K2239/48Blood cells, e.g. leukemia or lymphoma
    • AHUMAN NECESSITIES
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2024504944A 2021-07-28 2022-07-28 ユニバーサル受容体免疫細胞療法 Pending JP2024527963A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2021902320A AU2021902320A0 (en) 2021-07-28 Universal receptor immune cell therapy
AU2021902320 2021-07-28
PCT/AU2022/050795 WO2023004461A1 (en) 2021-07-28 2022-07-28 Universal receptor immune cell therapy

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Publication Number Publication Date
JP2024527963A true JP2024527963A (ja) 2024-07-26
JP2024527963A5 JP2024527963A5 (https=) 2025-08-05

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JP2024504944A Pending JP2024527963A (ja) 2021-07-28 2022-07-28 ユニバーサル受容体免疫細胞療法

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US (1) US20240366665A1 (https=)
EP (1) EP4376855A4 (https=)
JP (1) JP2024527963A (https=)
KR (1) KR20240043774A (https=)
CN (1) CN117915932A (https=)
AU (1) AU2022316596A1 (https=)
CA (1) CA3227128A1 (https=)
IL (1) IL310386A (https=)
WO (1) WO2023004461A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9233125B2 (en) * 2010-12-14 2016-01-12 University Of Maryland, Baltimore Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer
US11377481B2 (en) * 2015-12-22 2022-07-05 The Trustees Of The University Of Pennsylvania SpyCatcher and SpyTag: universal immune receptors for T cells
EP3529268B1 (en) * 2016-10-19 2025-02-26 The Scripps Research Institute Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
CA3055200A1 (en) * 2017-03-03 2018-09-07 Obsidian Therapeutics, Inc. Compositions and methods for immunotherapy
EP4588483A3 (en) * 2018-10-03 2025-09-24 University of Pittsburgh- Of the Commonwealth System of Higher Education Covalent adaptor synnotch and chimeric antigen receptors (cars) for programmable antigen-targeting
US20210107969A1 (en) * 2019-07-09 2021-04-15 The Johns Hopkins University Molecules, compositions and methods for treatment of cancer
CN115397439A (zh) * 2020-01-24 2022-11-25 宾夕法尼亚大学理事会 表达通用免疫受体的工程化细胞活性的定量控制

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KR20240043774A (ko) 2024-04-03
AU2022316596A1 (en) 2024-02-15
WO2023004461A1 (en) 2023-02-02
EP4376855A4 (en) 2025-10-15
IL310386A (en) 2024-03-01
US20240366665A1 (en) 2024-11-07
EP4376855A1 (en) 2024-06-05
CN117915932A (zh) 2024-04-19
CA3227128A1 (en) 2023-02-02

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