CN117860718A - 金刚烷胺组合物、其制备和使用方法 - Google Patents
金刚烷胺组合物、其制备和使用方法 Download PDFInfo
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- CN117860718A CN117860718A CN202410045779.2A CN202410045779A CN117860718A CN 117860718 A CN117860718 A CN 117860718A CN 202410045779 A CN202410045779 A CN 202410045779A CN 117860718 A CN117860718 A CN 117860718A
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- Prior art keywords
- amantadine
- pharmaceutical composition
- pharmaceutically acceptable
- hours
- acceptable salt
- Prior art date
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- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
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|---|---|---|---|
| US201762549921P | 2017-08-24 | 2017-08-24 | |
| US62/549,921 | 2017-08-24 | ||
| CN201880058525.7A CN111372578A (zh) | 2017-08-24 | 2018-08-23 | 金刚烷胺组合物、其制备和使用方法 |
| PCT/US2018/047754 WO2019040748A1 (en) | 2017-08-24 | 2018-08-23 | AMANTADINE COMPOSITIONS, THEIR PREPARATION, AND METHODS OF USE |
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| CN201880058525.7A Division CN111372578A (zh) | 2017-08-24 | 2018-08-23 | 金刚烷胺组合物、其制备和使用方法 |
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| CN117860718A true CN117860718A (zh) | 2024-04-12 |
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| CN202410045779.2A Pending CN117860718A (zh) | 2017-08-24 | 2018-08-23 | 金刚烷胺组合物、其制备和使用方法 |
| CN201880058525.7A Pending CN111372578A (zh) | 2017-08-24 | 2018-08-23 | 金刚烷胺组合物、其制备和使用方法 |
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| CN201880058525.7A Pending CN111372578A (zh) | 2017-08-24 | 2018-08-23 | 金刚烷胺组合物、其制备和使用方法 |
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| BR112012013487A2 (pt) | 2009-12-02 | 2017-10-03 | Adamas Pharmaceuticals Inc | Composições de amantadina e métodos de uso |
| WO2014204933A1 (en) | 2013-06-17 | 2014-12-24 | Adamas Pharmaceuticals, Inc. | Amantadine compositions and methods of use |
| IL272834B2 (en) | 2017-08-24 | 2024-08-01 | Adamas Pharma Llc | Amantadine compositions, preparations thereof, and methods of use |
| US11441653B1 (en) | 2021-05-20 | 2022-09-13 | Dana Automotive Systems Group, Llc | Integrated gearbox in electric motor systems |
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2019
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| US11065213B2 (en) | 2021-07-20 |
| US20220117914A1 (en) | 2022-04-21 |
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| JP2020531543A (ja) | 2020-11-05 |
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| WO2019040748A1 (en) | 2019-02-28 |
| US11077073B2 (en) | 2021-08-03 |
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| EP3672581A1 (en) | 2020-07-01 |
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| US12233033B2 (en) | 2025-02-25 |
| AU2018320946A1 (en) | 2020-04-16 |
| EP3672581A4 (en) | 2021-05-19 |
| IL272834B2 (en) | 2024-08-01 |
| US20190262285A1 (en) | 2019-08-29 |
| JP2024159885A (ja) | 2024-11-08 |
| AU2018320946B2 (en) | 2024-05-02 |
| US20200069614A1 (en) | 2020-03-05 |
| JP2023009251A (ja) | 2023-01-19 |
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