CN117795082A - 抗EGFRviii抗体、多肽、表达前述多肽的细胞、包含前述细胞的医药组合物、前述细胞的制造方法、及包含编码前述多肽的碱基序列的多核苷酸或载体 - Google Patents

抗EGFRviii抗体、多肽、表达前述多肽的细胞、包含前述细胞的医药组合物、前述细胞的制造方法、及包含编码前述多肽的碱基序列的多核苷酸或载体 Download PDF

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CN117795082A
CN117795082A CN202280048712.3A CN202280048712A CN117795082A CN 117795082 A CN117795082 A CN 117795082A CN 202280048712 A CN202280048712 A CN 202280048712A CN 117795082 A CN117795082 A CN 117795082A
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amino acid
cells
acid sequence
cell
seq
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玉田耕治
佐古田幸美
安达圭志
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Neuer Immune Biotechnology Co ltd
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Neuer Immune Biotechnology Co ltd
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4203—Receptors for growth factors
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CN202280048712.3A 2021-07-16 2022-07-14 抗EGFRviii抗体、多肽、表达前述多肽的细胞、包含前述细胞的医药组合物、前述细胞的制造方法、及包含编码前述多肽的碱基序列的多核苷酸或载体 Pending CN117795082A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021118056 2021-07-16
JP2021-118056 2021-07-16
PCT/JP2022/027735 WO2023286840A1 (ja) 2021-07-16 2022-07-14 抗ＥＧＦＲｖｉｉｉ抗体、ポリペプチド、前記ポリペプチドを発現する細胞、前記細胞を含む医薬組成物、前記細胞の製造方法、及び、前記ポリペプチドをコードする塩基配列を含むポリヌクレオチド又はベクター

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CN117795082A true CN117795082A (zh) 2024-03-29

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CN202280048712.3A Pending CN117795082A (zh) 2021-07-16 2022-07-14 抗EGFRviii抗体、多肽、表达前述多肽的细胞、包含前述细胞的医药组合物、前述细胞的制造方法、及包含编码前述多肽的碱基序列的多核苷酸或载体

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US (1) US20250121002A1 (https=)
EP (1) EP4372088A4 (https=)
JP (1) JPWO2023286840A1 (https=)
KR (1) KR20240034205A (https=)
CN (1) CN117795082A (https=)
AU (1) AU2022312311A1 (https=)
CA (1) CA3225682A1 (https=)
TW (1) TW202317634A (https=)
WO (1) WO2023286840A1 (https=)

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US20250332195A1 (en) * 2021-07-16 2025-10-30 Noile-Immune Biotech Inc. Chimeric antigen receptor, cell expressing said receptor, pharmaceutical composition including said cell, method for producing said cell, and polynucleotide or vector including nucleotide sequence encoding said chimeric antigen receptor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2832540C (en) * 2011-04-08 2020-09-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-epidermal growth factor receptor variant iii chimeric antigen receptors and use of same for the treatment of cancer
JP6647868B2 (ja) * 2013-02-20 2020-02-14 ノバルティス アーゲー ヒト化抗ＥＧＦＲｖＩＩＩキメラ抗原受容体を用いたがんの処置
ES2857226T3 (es) * 2014-03-15 2021-09-28 Novartis Ag Receptor de antígeno quimérico regulable
WO2016016341A1 (en) * 2014-07-29 2016-02-04 Cellectis EGFRvIII SPECIFIC CHIMERIC ANTIGEN RECEPTORS FOR CANCER IMMUNOTHERAPY
TWI755547B (zh) * 2016-01-21 2022-02-21 美商輝瑞股份有限公司 靶向表皮生長因子受體變異體iii之嵌合型抗原受體
CN109219618B (zh) * 2016-01-21 2022-08-09 辉瑞大药厂 针对表皮生长因子受体变体iii和cd3的单特异性和双特异性抗体及其用途
CA3017442A1 (en) 2016-03-17 2017-09-21 Yamaguchi University Immunocompetent cell and expression vector expressing regulatory factors of immune function
CN110461881B (zh) 2017-03-27 2023-06-23 诺伊尓免疫生物科技株式会社 嵌合抗原受体
EP3753952A4 (en) * 2017-12-13 2022-04-13 XDCExplorer (Shanghai) Co., Ltd. EGFRVIII ANTIBODY AND CONJUGATE, AND METHODS FOR ITS PRODUCTION AND USE
KR101953299B1 (ko) * 2018-08-02 2019-02-28 의료법인 성광의료재단 EGFRvIII에 대한 항체 및 이의 이용

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TW202317634A (zh) 2023-05-01
EP4372088A4 (en) 2025-07-23
US20250121002A1 (en) 2025-04-17
EP4372088A1 (en) 2024-05-22
JPWO2023286840A1 (https=) 2023-01-19
CA3225682A1 (en) 2023-01-19
KR20240034205A (ko) 2024-03-13
AU2022312311A1 (en) 2024-02-08
WO2023286840A1 (ja) 2023-01-19

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