CN117695356A - Traditional Chinese medicine composition for removing freckles and acnes and preparation method thereof - Google Patents

Traditional Chinese medicine composition for removing freckles and acnes and preparation method thereof Download PDF

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CN117695356A
CN117695356A CN202211086284.1A CN202211086284A CN117695356A CN 117695356 A CN117695356 A CN 117695356A CN 202211086284 A CN202211086284 A CN 202211086284A CN 117695356 A CN117695356 A CN 117695356A
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余灵玉
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    • A61K36/484Glycyrrhiza (licorice)
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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Abstract

The invention discloses a traditional Chinese medicine composition for removing freckles and acnes, which comprises the following raw material medicines: radix Angelicae Dahuricae, rhizoma Bletillae, radix Trichosanthis, bulbus Fritillariae Cirrhosae, and Glycyrrhrizae radix. The raw material composition provided by the invention has the effects of activating blood and removing stasis, promoting tissue regeneration, astringing, softening hard masses, detoxifying and whitening, is suitable for treating pigmentation on the surface of skin to form color spots, such as freckle, sunburn, black speck, chloasma, senile plaque and other pigment-obstructing skin diseases, and is also suitable for treating acne caused by excessive damp-heat accumulation and spleen deficiency and excessive dampness. The traditional Chinese medicine composition disclosed by the invention has the advantages of freckle and acne removal, clinical curative effect improvement, patient life quality improvement, safety in clinical application and no side effect.

Description

Traditional Chinese medicine composition for removing freckles and acnes and preparation method thereof
The invention relates to a traditional Chinese medicine composition for treating pigment spots and acnes, a preparation method and application thereof, and belongs to the field of traditional Chinese medicines.
Background
Ultraviolet light has a strong skin irritation and when exposed to ultraviolet radiation for a long period of time, it causes pigmentation and plaque formation on the face, commonly known as sunburn. The traditional Chinese medicine disease name corresponding to chloasma is liver spots, and the liver spots are related to liver failure due to one of the pathogenesis reasons of the liver spots. In addition, it is also related to endocrine, post partum and sun exposure. Since liver spots are called, the traditional Chinese medicine can be used for treating the liver spots by using the medicines of nourishing blood, softening liver, soothing liver and regulating qi of the traditional Chinese medicine; the conventional treatment comprises applying vitamin C and vitamin E to relieve symptoms, applying Chinese medicinal powder, taking SANBAITANG for treatment, and laser or freezing for treatment, or applying hydroquinone cream for external use. The Yu-containing powder needs to be prepared by white spirit, strong smell is not acceptable to most people, and excessive vitamin taking has adverse effect on health, and laser cryotherapy obviously causes damage to skin. Cyasma is common in gestation and occurs due to increased melanin production stimulated by estrogen, resulting in yellow brown spots. Cyasma is usually caused by endocrine dyscrasia, is particularly obvious during pregnancy, and can be relieved or eliminated after production. When female is suffering from cyasma, medicines with the functions of activating qi and blood, nourishing yin and expelling toxin and maintaining beauty and keeping young are usually used for treatment, such as oral ease pills, black chicken white phoenix pills, six-ingredient rehmannia pills, chinese aster Liangfang Yuyan pills, qiju Dihuang pills, taohong four-ingredient soup and the like, and the medicines have relatively stable treatment effects, but for pregnant women, the worry that the fetal development is influenced by the medicines is inevitably caused by the oral traditional Chinese medicine preparation. Acne is a skin disease which is common in clinic, is usually called acne, is well developed on the face, and is mainly represented by acne formed by seborrhea or red inflammatory pimples, nodules and even cysts, and the sequelae of acne comprise post-acne rosacea, post-acne pigmentation and post-acne scar. The pathogenesis of acne is mainly considered to be that hormone secretion disorder, namely androgen level is high in western medicine, bacterial infection, and dietary stimulation or genetic factors are caused, and antibiotics and external application of dovudine and tretinoin are mainly used for treatment. However, dialectical differentiation is needed in the treatment of traditional Chinese medicine, which considers that acne is mostly affected by skin dampness, heat, toxin and the like and pathological changes occur. In young people, qi and blood are exuberant, while the head and face parts are the regions of the face, and many yang meridians are distributed on the face, which are the meridians of qi and blood, so that the problems of dampness, heat and toxicity are easy to occur, and if the viscera function of a patient is abnormal, such as liver depression and qi stagnation, spleen deficiency and failure of transportation, and disharmony of thoroughfare and conception vessels, the pathological problems of dampness, heat and toxicity, even blood stasis and phlegm can also be caused. The disease is well developed in young people, and for some patients, the effect on life of the disease is even more than that of acne lesions due to post-inflammatory pigmentation caused by acne. Because of the difficulty in treating pigmentation, it is significant to find safe and effective treatments and daily care.
Aiming at pigmentation caused by the reasons, the inventor researches from the perspective of traditional Chinese medicine, considers the purposes of convenient use and reduction of toxic and side effects, and aims at pathogenesis and symptoms similar to the symptoms of the symptoms, the invention provides a traditional Chinese medicine composition, a group of medicines for detoxification, anti-inflammation, pus discharge and detumescence are selected, and the medicines are ground, mixed into paste with purified water for external application or purified for external application, so that the traditional Chinese medicine composition is beneficial to patients unsuitable for oral medicines, such as pregnant women or women in lactation; or grinding, and mixing with warm boiled water for oral administration. The traditional Chinese medicine composition contains active ingredients such as volatile oil, and can fully integrate the effects of the medicines, thereby achieving the treatment effects of fading spots, removing acnes, diminishing inflammation and moistening facial complexion.
The prior art discloses a composition for whitening and removing freckles, a preparation method and a using method thereof (publication number: CN 113893205A), wherein the composition for whitening and removing freckles comprises the following components in parts by weight: 35-40 parts of bletilla striata, 25-30 parts of Japanese ampelopsis root, 25-30 parts of dahurian angelica root, 35-40 parts of giant typhonium rhizome, 15-21 parts of fragrant solomonseal rhizome, 28-34 parts of amur corktree bark, 5-8 parts of liquoric root, 11-15 parts of Chinese dodder seed and 10-12 parts of borneol; the traditional Chinese medicine for removing chloasma and the mask (publication number is CN 113318190A) comprise semen cuscutae, ligusticum chuanxiong, radix salviae miltiorrhizae, rhodiola rosea, liquorice, radix scutellariae, centella asiatica, purslane, poria cocos, bighead atractylodes rhizome, radix angelicae, bletilla striata, radix paeoniae alba, radix ampelopsis and pearl powder. The composition disclosed in the prior art has the advantages of complex components, high manufacturing cost and certain side effects. The invention relates to a traditional Chinese medicine composition for removing freckle and acne and a preparation method thereof, wherein the composition for removing freckle and acne has relatively simple components, and main components only comprise five components of dahurian angelica root, bletilla striata, radix trichosanthis, unibract fritillary bulb and liquorice, and the composition has the advantages of simple preparation method, relatively low cost and no toxic or side effect.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating pigmentation, speckle reduction and acne removal. The purposes of lightening color spots, clearing heat and removing acnes are achieved by selectively damaging melanocytes and clearing heat and purging fire, detoxifying and relieving swelling on facial skin.
The invention further aims to provide a preparation method of the traditional Chinese medicine composition for removing spots and acnes.
In order to achieve the aim of the invention, the traditional Chinese medicine composition for spot-removing and acne-removing is a brand new Chinese patent medicine formula, which is a preparation containing the following raw materials, different from the Chinese patent medicine disclosed in the prior art:
20-30 parts of radix angelicae, 10-20 parts of bletilla striata, 10-20 parts of radix trichosanthis, 20-30 parts of fritillaria cirrhosa and 20-30 parts of liquorice.
Among them, preferred are: 10-20 parts of radix angelicae, 5-10 parts of bletilla striata, 5-10 parts of radix trichosanthis, 10-20 parts of fritillaria cirrhosa and 10-20 parts of liquorice.
More preferably: 15-25 parts of radix angelicae, 15-20 parts of bletilla striata, 8-15 parts of radix trichosanthis, 15-25 parts of fritillaria cirrhosa and 15-25 parts of liquorice.
Most preferably: 15 parts of radix angelicae, 15 parts of bletilla striata, 8 parts of radix trichosanthis, 15 parts of fritillaria cirrhosa and 15 parts of liquorice.
In order to obtain better medicinal effects, the fritillaria cirrhosa is wild fritillaria cirrhosa.
The weight parts of the invention are gram, two, kilogram, ton and other weight units commonly used in the field.
The composition of the traditional Chinese medicine composition is shown in Table 1 in detail compared with the composition of the traditional Chinese patent medicine in the prior art.
The preparation is powder, paste, capsule, tablet and granule. In addition, the traditional Chinese medicine composition can also comprise a medicinal carrier.
The medicine property and efficacy of the raw materials used in the traditional Chinese medicine composition are as follows:
radix angelicae: pungent and warm in flavor, is mainly used for treating wind-cold, headache, nasal obstruction or wind-cold-dampness arthralgia, and can dispel wind-cold-moving of skin. Bai Zhi is combined with jin Yin Hua and Tian Hua fen to dispel swelling and expel pus, and combined with Gua and Bei mu to treat sores, abscess and toxic swelling. The radix Angelicae Dahuricae contains natural antibacterial components, has effects of dispelling pathogenic wind, removing dampness, inducing resuscitation, relieving pain, resisting bacteria, etc., and has inhibiting effects on various bacteria such as Escherichia coli, bacillus dysenteriae, bacillus proteus, typhoid bacillus, paratyphoid bacillus, pseudomonas aeruginosa, cholera bacillus, etc., and also has effects of inhibiting virus activity, and improving disease resistance of human body. The angelica dahurica contains volatile oil, 29 compounds are detected in the volatile oil, and the volatile oil contains methyl cycloartane, 1-tetradecene, ethyl laurate and a plurality of furocoumarins with higher content. In addition, imperatorin, dahurian angelica toxin, scopoletin, angelicin, isopsornolactone, hydrated Bai Danggui element, isopsornolactone, oxidized imperatorin, anethole, carvacrol, palmitic acid, etc. are also included.
Bletilla striata: bitter and sweet in flavor and cool in nature. The main effects are hemostasis, promoting granulation, detumescence and tonifying lung, the traditional Chinese medicines are mainly used for treating diseases such as human tuberculosis, cough, tracheitis, traumatic hemorrhage and the like in traditional Chinese medicine, when the tuberculosis, gastroduodenal ulcer hemorrhage and the like are treated, the bletilla striata can be ground into fine powder in proper amount, the bletilla striata is taken for 3-9 times per day with boiled water, 3-6 g each time, and when the traumatic hemorrhage is treated, the bletilla striata can be ground into fine powder in proper amount, and the wound is externally rubbed. In addition, the bletilla striata has good treatment effect on scalds and burns, and the bletilla striata can be processed into powder during treatment, mixed into ointment by sesame oil, and then directly applied to the injured part.
Radix trichosanthis: cold-expelling, which is mainly used for treating symptoms such as thirst, diabetes, jaundice, lung dryness, hemoptysis, carbuncle, and hemorrhoid, etc., is a Chinese medicine with effects of clearing heat and purging pathogenic fire, promoting salivation to quench thirst, expelling pus and detumescence.
Bulbus Fritillariae Cirrhosae: bitter in nature and cold in taste, has a certain heat-clearing effect, can effectively reduce liver fire, contains alkaloid in fritillaria cirrhosa, and can directly act on central nerves to inhibit nerve reflex. The fritillaria cirrhosa has a certain antibacterial effect, and scientific experiments show that the fritillaria cirrhosa has obvious inhibition effect on the division of partial bacteria such as escherichia coli, staphylococcus aureus and the like, and can play roles in resisting bacteria, detoxifying and diminishing inflammation by inhibiting the propagation of the bacteria, so that the fritillaria cirrhosa has the effect of assisting in treating some viral inflammations, such as parotitis, and particularly has the optimal detoxification and diminishing inflammation effect of fritillaria cirrhosa.
White atractylodes rhizome: bitter and sweet taste, warm nature, and medical science origin states that white atractylodes rhizome has the functions of removing dampness, tonifying dryness, regulating the middle warmer, tonifying qi, warming the middle warmer, removing dampness in the spleen and stomach, removing stomach heat, strengthening the spleen and stomach, feeding diet and preventing abortion. The white atractylodes rhizome has a plurality of medicinal functions, has the effects of strengthening spleen and supplementing qi, drying dampness and promoting diuresis, stopping sweat and preventing miscarriage, is used for spleen deficiency and anorexia, abdominal distention and diarrhea, phlegm-fluid, dizziness and palpitation, edema, spontaneous sweat and fetal movement disorder, and is suitable for pregnant women. Animal experiments show that the white atractylodes rhizome contains volatile oil, mainly atractylol, atractylone, vitamin A substances and the like, has a sedative effect and an inhibitory effect on animal tumor growth, and has an inhibitory rate of 31% -49% on mouse sarcoma 180 [ in medical science report ].
Licorice root: the liquorice has better toxin expelling effect and reduces inflammatory stimulus, so that the liquorice can be used for treating carbuncles, sores, sore throat and swelling and pain, pesticide, food poisoning and the like. It can be used singly or combined with jin Yin Hua and Lian Qiao to treat common cold with the actions of clearing heat and removing toxicity. Licorice is often used to harmonize the intensity of certain drugs, and therefore is used in many prescriptions to harmonize various drugs.
The researchers of the invention consider that the mechanism of pigmentation caused by common skin diseases such as sunburn, cyasma and acne is different, for example, the in vivo hormone is possibly changed, so that the skin presents different colors; or oxidizing cells by sunlight and ultraviolet radiation to generate melanin to protect skin; or pigmentation after inflammation elimination; or pigmentation due to cosmetic effects, drug irritation; and genetic factors and the like can not be excluded. The optimal scheme of the treatment is to apply the Chinese medicine theory to make internal regulation and external treatment, wherein the internal regulation is to treat different etiologies based on differentiation of symptoms, and the general external treatment method for the symptoms is a group of Chinese medicinal compositions which can activate blood stasis, promote tissue regeneration, astringe, soften hardness and detoxify, and are simple, free from toxic and side effects and free from stimulation. The angelica dahurica in the formula has antibacterial efficacy and contains volatile oil, the common action of the active ingredients such as atractylol or atractylone in the bighead atractylodes rhizome is added, the bletilla striata with the effects of stopping bleeding, promoting granulation and relieving swelling, the radix trichosanthis with the effects of clearing heat and purging fire, promoting the production of body fluid to quench thirst, expelling pus and relieving swelling, the fritillaria cirrhosa capable of resisting bacteria and inhibiting viruses and diminishing inflammation and the liquorice with the effects of expelling toxin and relieving inflammation stimulus and harmonizing various medicines are matched, the active ingredients are fully exerted, and the practice proves that the traditional Chinese medicine composition has good treatment effect on sunburn, cyasma and acne, is simple and convenient to use, and is safe and free of side effects.
The invention also aims at providing a preparation method of the traditional Chinese medicine composition. A preparation method of a traditional Chinese medicine composition for removing spots and acnes comprises the following steps:
1. mixing radix Angelicae Dahuricae, rhizoma Bletillae, radix Trichosanthis, bulbus Fritillariae Cirrhosae, and Glycyrrhrizae radix, stirring, and mixing;
2. cleaning the above mixture rapidly, oven drying, pulverizing, sieving with 80-120 mesh sieve, and sterilizing.
The traditional Chinese medicine composition can be added with conventional auxiliary materials (starch, vegetable oil and the like) and prepared into clinically acceptable paste, powder, tablets, capsules or granules according to a conventional method; preferably a powder.
In addition to the effective pharmaceutical ingredients, the Chinese medicinal composition of the invention can also comprise carriers such as excipients and auxiliary materials which are allowed to be used in the pharmacy, wherein the carriers have the functions of helping the processing of the effective ingredients into preparations and transporting the effective ingredients to the action sites in the body.
The Chinese medicinal composition can be applied in the form of a medicinal preparation, for example, a solid, semi-solid or liquid medicinal preparation, which contains the Chinese medicinal composition as an effective component, and is mixed with an organic or inorganic excipient and auxiliary materials, so that the Chinese medicinal composition is suitable for external application and gastrointestinal tract internal administration and absorption. For example, the active ingredient may be formulated into tablets, pills, capsules, solutions, emulsions, suspensions, and any other dosage form that may be employed, in combination with conventional non-toxic pharmaceutical excipients. Excipients or adjuvants of the present invention include talc, water, dextrose, lactose, acacia, gelatin, mannitol, starches, magnesium trisilicate, corn starch, keratin, colloidal silicon, potato starch and any carrier capable of being prepared in solid, semi-solid or liquid form. In addition, auxiliary agents such as auxiliary agents, stabilizing agents, thickening agents, coloring agents, flavoring agents, and the like may also be used.
The Chinese medicinal composition can also be prepared into liquid preparations, such as oral liquid, including aqueous solution, syrup with proper taste, water or oil suspension, and the like.
The external preparation of the traditional Chinese medicine composition is usually powder and paste.
The oral administration of the traditional Chinese medicine composition is generally powder, capsules and tablets.
Route of administration: the administration route of the composition of the invention comprises external application to affected parts and oral administration.
Dosage is as follows: the dosage to be administered depends on the age, weight, health condition, course of treatment, individual differences and differences in dosage form and route of administration of the patient. The optimum range of effective amounts of each component can be determined by one skilled in the art according to individual needs.
Detailed Description
To further illustrate the invention and its advantages, the following specific examples are given with the understanding that they are merely illustrative and are in no way limiting. In the examples which follow, all parts and percentages are given by weight unless otherwise indicated.
Example 1: clinical observation of the Chinese medicinal composition for preventing/treating sunburn
The beneficial effects of the present invention are illustrated by the summary of the clinical efficacy of the present invention for the treatment/prevention of sunburn in the following approximately 3 years.
1 object and method
1.1 clinical data sunburn patients were all from the department of clinical medicine, the institute of the hall, the island kernel hospital, the sea, and the sea, in the Hainan province, 23 cases.
1.2 method of treatment the traditional Chinese medicine composition of the invention is ground into fine powder, purified water is used for preparing a facial mask, and the facial mask is externally applied to the face: 15g of angelica dahurica, 15g of bletilla striata, 8g of radix trichosanthis, 15g of fritillaria cirrhosa and 15g of liquorice,
the using method comprises the following steps: after cleaning face in the morning and evening, each application is carried out once, each time is kept for 45 minutes, and the face is cleaned by clear water
1.3 observations and follow-up
Follow-up treatment is carried out at 1-2 weeks after treatment is started, all indexes and facial stain changes are recorded by medication, and if the patients still do not recover, follow-up treatment is continued until recovery. The observation items and indices are shown in table 2 below:
table 2: observation item and index
1.4 evaluation of Total efficacy
And (3) healing: efficacy index = 1;
the effect is shown: the curative effect index is 0.6-0.99;
the method is effective: the curative effect index is 0.3-0.59;
invalidation: the efficacy index is <0.3.
Efficacy index = (pre-treatment score-post-treatment score)/pre-treatment score
1.3 statistical methods
All data were processed using Excel 2007 software statistical analysis.
2 results
2.1 general data
Table 3: case cases
Number of examples Man's body Female Average age (age)
23 10 13 29
Table 4: efficacy comparison for treating sunburn
Number of examples Before treatment After treatment
13 1.50±0.75 0.36±0.32
Table 5 comparative efficacy of treatment of cyasma
Number of examples Before treatment After treatment
3 2.50±1.14 0.32±0.34
Table 6 comparison of efficacy of treatment of acne
Number of examples Before treatment After treatment
7 2.5±0.74 0.33±0.34
TABLE 7 Total efficacy comparison
Number of examples Healing of the wound Has obvious effect Effective and effective Invalidation of Total effective rate (%)
23 15 7 1 0 100
2.2 adverse reactions
No obvious abnormality is found, and no adverse reaction is found after the treatment is finished
2.3 case analysis
Case 1 Dragon, woman, age 38
Yellow brown plaque on the cheekbones of the face has been known for 3 years; the face is dark, has no luster, can aggravate after sunburn, and at ordinary times mood is dysphoria, irritability, bad sleep, and the last differentiation is: chloasma caused by liver depression and blood deficiency.
The treatment method comprises the following steps: the Chinese medicinal composition is orally taken after being mixed with warm water.
Prescription (Unit) g
25 parts of dahurian angelica root, 20 parts of bletilla striata, 10 parts of radix trichosanthis, 15 parts of fritillary bulb and 20 parts of liquorice
After ten days of external application, the facial plaque is obviously reduced, the external application is continued for 20 days, and the chloasma plaque is basically reduced.
Case 2 Zhang Mou, male, 27 years old
The two sides face repeatedly make nodular acne for one year, and there is red pimple on the two sides face when seeing a doctor, there is little itching, has little pustule, and facial grease secretes exuberantly, and diagnosis is: acne.
The treatment method comprises the following steps: the traditional Chinese medicine composition is pulverized, is taken orally after being mixed with warm boiled water twice a day.
Prescription (Unit) g
25 parts of dahurian angelica root, 20 parts of bletilla striata, 10 parts of radix trichosanthis, 15 parts of fritillary bulb and 20 parts of liquorice,
after ten days of continuous administration, facial symptoms are relieved by 80%; the external application is changed into continuous use for ten days, and the symptoms completely disappear.
Case 3 Xu Mou, female, 31 years old
Facial acne spreads with pus head
The treatment method comprises the following steps: the Chinese medicinal composition is externally applied
Prescription (Unit) g
25 parts of dahurian angelica root, 20 parts of bletilla striata, 10 parts of radix trichosanthis, 15 parts of fritillary bulb and 20 parts of liquorice
Seven days after external application, the acne is shriveled, the pus head is crusted, the red swelling is basically disappeared, the external application is continued for seven days, the crusted is completely removed, and the skin is basically restored.
Case 4 Zhong Mou, female, age 38
Acne, and skin induration with pain and redness.
The treatment method comprises the following steps: the Chinese medicinal composition is externally applied
Prescription (Unit) g
25 parts of dahurian angelica root, 20 parts of bletilla striata, 10 parts of radix trichosanthis, 15 parts of fritillary bulb and 20 parts of liquorice
After seven days of external application, the red swelling is improved, the pain is not caused, the external application is continued for seven days, the red swelling is basically disappeared, and the skin is basically restored.
Case 5 Lin Mou, female, 28 years old
Facial acne repeatedly attacks, skin reddening and local reddening and swelling, and facial grease secretion is vigorous.
The treatment method comprises the following steps: the Chinese medicinal composition is externally applied
Prescription (Unit) g
25 parts of dahurian angelica root, 20 parts of bletilla striata, 10 parts of radix trichosanthis, 15 parts of fritillary bulb and 20 parts of liquorice
Seven days after external application, the red swelling is improved, the condition of facial redness is improved, the external application is continued for ten days, the red swelling is basically disappeared, and the facial skin is better recovered.
Case 6 Huang Mou, female, 29 years old
Dark face, no luster, large area of black spots, and sunburn
The treatment method comprises the following steps: the Chinese medicinal composition is externally applied
Prescription (Unit) g
25 parts of dahurian angelica root, 20 parts of bletilla striata, 10 parts of radix trichosanthis, 15 parts of fritillary bulb and 20 parts of liquorice
Seven days after the external application, the black color spots become shallow, the facial symptoms are improved, the external application is continued for ten days, the color spots basically disappear, the face is shiny, and the skin is basically restored.

Claims (6)

1. The traditional Chinese medicine composition for removing freckles and acnes is characterized by being a preparation prepared from the following raw materials:
20-30 parts of radix angelicae, 10-20 parts of bletilla striata, 10-20 parts of radix trichosanthis, 20-30 parts of fritillaria cirrhosa and 20-30 parts of liquorice.
2. The traditional Chinese medicine composition for removing freckles and acnes according to claim 1, which is characterized by being a preparation prepared from the following raw materials:
10-20 parts of radix angelicae, 5-10 parts of bletilla striata, 5-10 parts of radix trichosanthis, 10-20 parts of fritillaria cirrhosa and 10-20 parts of liquorice.
3. The freckle and acne removing traditional Chinese medicine composition according to claim 1, which is characterized in that
Thus, it is a preparation made from the following raw materials:
15-25 parts of radix angelicae, 15-20 parts of bletilla striata, 8-15 parts of radix trichosanthis, 15-25 parts of fritillaria cirrhosa and 15-25 parts of liquorice.
4. The freckle and acne removing traditional Chinese medicine composition according to claim 1, which is characterized in that
Thus, it is a preparation made from the following raw materials:
15 parts of radix angelicae, 15 parts of bletilla striata, 8 parts of radix trichosanthis, 15 parts of fritillaria cirrhosa and 15 parts of liquorice.
5. The freckle and acne removing traditional Chinese medicine composition according to any one of claims 1 to 4, wherein the fritillaria cirrhosa is wild fritillaria cirrhosa.
6. A method for preparing the traditional Chinese medicine composition for removing freckles and acnes according to any one of claims 1 to 5, which is characterized by comprising the following steps:
(1) Mixing radix Angelicae Dahuricae, rhizoma Bletillae, radix Trichosanthis, bulbus Fritillariae Cirrhosae, and Glycyrrhrizae radix, stirring, and mixing;
(2) Cleaning the above mixture rapidly, oven drying, pulverizing, sieving with 80-120 mesh sieve, and sterilizing.
CN202211086284.1A 2022-09-06 2022-09-06 Traditional Chinese medicine composition for removing freckles and acnes and preparation method thereof Pending CN117695356A (en)

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CN117695356A true CN117695356A (en) 2024-03-15

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