CN117642668A - 物镜和样本分析装置 - Google Patents

物镜和样本分析装置 Download PDF

Info

Publication number
CN117642668A
CN117642668A CN202280048537.8A CN202280048537A CN117642668A CN 117642668 A CN117642668 A CN 117642668A CN 202280048537 A CN202280048537 A CN 202280048537A CN 117642668 A CN117642668 A CN 117642668A
Authority
CN
China
Prior art keywords
objective lens
light
lens
flow channel
sample analyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280048537.8A
Other languages
English (en)
Chinese (zh)
Inventor
野中干修
长江聪史
畠山丈司
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Group Corp
Original Assignee
Sony Group Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Group Corp filed Critical Sony Group Corp
Publication of CN117642668A publication Critical patent/CN117642668A/zh
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B13/00Optical objectives specially designed for the purposes specified below
    • G02B13/18Optical objectives specially designed for the purposes specified below with lenses having one or more non-spherical faces, e.g. for reducing geometrical aberration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/02Objectives
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN202280048537.8A 2021-07-21 2022-06-20 物镜和样本分析装置 Pending CN117642668A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163224125P 2021-07-21 2021-07-21
US63/224,125 2021-07-21
PCT/JP2022/024507 WO2023002788A1 (ja) 2021-07-21 2022-06-20 対物レンズ及び試料分析装置

Publications (1)

Publication Number Publication Date
CN117642668A true CN117642668A (zh) 2024-03-01

Family

ID=84979960

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280048537.8A Pending CN117642668A (zh) 2021-07-21 2022-06-20 物镜和样本分析装置

Country Status (5)

Country Link
US (1) US20240329370A1 (https=)
EP (1) EP4375724A4 (https=)
JP (1) JPWO2023002788A1 (https=)
CN (1) CN117642668A (https=)
WO (1) WO2023002788A1 (https=)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60209715A (ja) * 1984-04-03 1985-10-22 Nippon Kogaku Kk <Nikon> 高倍率アポクロマ−ト対物レンズ
US6510007B1 (en) 2001-08-21 2003-01-21 Becton Dickinson And Company Flow cytometry lens system
JP4033651B2 (ja) * 2001-09-03 2008-01-16 オリンパス株式会社 顕微鏡対物レンズ
JP4236893B2 (ja) * 2002-10-04 2009-03-11 シスメックス株式会社 菌計数方法および菌計数装置
JP5536995B2 (ja) * 2007-07-17 2014-07-02 オリンパス株式会社 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム
JP5985140B2 (ja) 2010-04-28 2016-09-06 ソニー株式会社 蛍光強度補正方法、蛍光強度算出方法及び蛍光強度算出装置
JP5885537B2 (ja) * 2012-02-28 2016-03-15 オリンパス株式会社 顕微鏡対物レンズ
JP2014021274A (ja) * 2012-07-18 2014-02-03 Hamamatsu Photonics Kk 共焦点光生成レンズユニット、光学装置および顕微鏡
JP2015145829A (ja) * 2014-02-03 2015-08-13 ソニー株式会社 蛍光信号取得装置及び蛍光信号取得方法
CN104459967B (zh) * 2014-12-29 2017-02-22 中国科学院长春光学精密机械与物理研究所 一种用于流式细胞仪宽波带大景深显微物镜光学系统
JP2017116845A (ja) * 2015-12-25 2017-06-29 オリンパス株式会社 顕微鏡対物レンズ
JP7338336B2 (ja) 2018-09-10 2023-09-05 ソニーグループ株式会社 微小粒子分取装置、細胞治療薬製造装置、微小粒子分取方法、及びプログラム
JP2021076451A (ja) * 2019-11-07 2021-05-20 ソニー株式会社 検出光学系、検出装置、フローサイトメータ及びイメージングサイトメータ

Also Published As

Publication number Publication date
JPWO2023002788A1 (https=) 2023-01-26
EP4375724A4 (en) 2024-11-13
US20240329370A1 (en) 2024-10-03
EP4375724A1 (en) 2024-05-29
WO2023002788A1 (ja) 2023-01-26

Similar Documents

Publication Publication Date Title
JP6352713B2 (ja) フローサイトメータ、粒子分析装置およびフローサイトメトリー法
CN103852409B (zh) 用于流式细胞仪中血细胞的成像系统
US20240142366A1 (en) Methods and systems for fast recompensation of flow cytometery data
CN107209102B (zh) 光学检测系统及其使用方法
US7724371B2 (en) Device for examining a fluid by uniform illumination using a configured light guide
CN115335682A (zh) 信息处理装置、信息处理方法、程序和光学测量系统
US12578259B2 (en) Biological sample analyzer
Ojaghi et al. Label-free deep-UV microscopy detection and grading of neutropenia using a passive microfluidic device
Yang et al. Deep ultraviolet high-resolution microscopic hyperspectral imager and its biological tissue detection
Huang et al. Deep learning-assisted smartphone-based quantitative microscopy for label-free peripheral blood smear analysis
US20120215456A1 (en) System and method for cellular optical wavefront sensing
US20240329370A1 (en) Objective lens and sample analyzer
WO2021070847A1 (en) Particle detection apparatus, information processing apparatus, information processing method, and particle detection method
US20250067653A1 (en) Information processing device and information processing system
JP2024127759A (ja) フローサイトメータ、生体試料分析システム、及び光検出装置
US12596123B2 (en) Information processing apparatus, biological specimen analysis method, biological specimen detection apparatus, and biological specimen detection system
US12379304B2 (en) Particle analyzer, particle analysis method, and optical measurement device
US20220404262A1 (en) Optical measurement device and lens structure
EP4624896A1 (en) Biological sample analysis device, biological sample analysis system, and method for verifying status of biological sample analysis device
US12078586B2 (en) Microparticle measurement device, microparticle sorting device, microparticle measurement system, and microparticle sorting system
US12613182B2 (en) Concentration measurement device
JP7786459B2 (ja) 濃度測定装置
Ma et al. Design of a digital PCR optical detection system with multiple fluorescent microdroplets
CN121605338A (zh) 用于生物样本观察的光学系统、测量装置、测量方法和分析程序
WO2023171463A1 (ja) 情報処理装置及び情報処理システム

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination