CN117598315A - Pesticide composition for preventing and treating Siraitia grosvenorii southern blight - Google Patents
Pesticide composition for preventing and treating Siraitia grosvenorii southern blight Download PDFInfo
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- CN117598315A CN117598315A CN202310860186.7A CN202310860186A CN117598315A CN 117598315 A CN117598315 A CN 117598315A CN 202310860186 A CN202310860186 A CN 202310860186A CN 117598315 A CN117598315 A CN 117598315A
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- 239000000203 mixture Substances 0.000 title claims abstract description 30
- 241001409321 Siraitia grosvenorii Species 0.000 title claims abstract description 26
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 title claims abstract description 26
- 239000000575 pesticide Substances 0.000 title claims abstract description 21
- 239000005783 Fluopyram Substances 0.000 claims abstract description 20
- KVDJTXBXMWJJEF-UHFFFAOYSA-N fluopyram Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CCNC(=O)C1=CC=CC=C1C(F)(F)F KVDJTXBXMWJJEF-UHFFFAOYSA-N 0.000 claims abstract description 19
- 239000005839 Tebuconazole Substances 0.000 claims abstract description 18
- PXMNMQRDXWABCY-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Chemical compound C1=NC=NN1CC(O)(C(C)(C)C)CCC1=CC=C(Cl)C=C1 PXMNMQRDXWABCY-UHFFFAOYSA-N 0.000 claims abstract description 17
- FEACDOXQOYCHKU-UHFFFAOYSA-N Gougerotin Natural products CNCC(=O)NC1=NC(=O)N(C=C1)C2OC(C(O)C(NC(=O)C(N)CO)C2O)C(=O)N FEACDOXQOYCHKU-UHFFFAOYSA-N 0.000 claims abstract description 17
- AMNAZJFEONUVTD-KEWDHRJRSA-N (2s,3s,4s,5r,6r)-6-(4-amino-2-oxopyrimidin-1-yl)-4,5-dihydroxy-3-[[(2s)-3-hydroxy-2-[[2-(methylamino)acetyl]amino]propanoyl]amino]oxane-2-carboxamide Chemical compound O1[C@H](C(N)=O)[C@@H](NC(=O)[C@H](CO)NC(=O)CNC)[C@H](O)[C@@H](O)[C@@H]1N1C(=O)N=C(N)C=C1 AMNAZJFEONUVTD-KEWDHRJRSA-N 0.000 claims abstract description 16
- WHAAPCGHVWVUEX-GGWOSOGESA-N (E,E)-Piperlonguminine Chemical compound CC(C)CNC(=O)\C=C\C=C\C1=CC=C2OCOC2=C1 WHAAPCGHVWVUEX-GGWOSOGESA-N 0.000 claims description 9
- WHAAPCGHVWVUEX-UHFFFAOYSA-N Piperlonguminine Natural products CC(C)CNC(=O)C=CC=CC1=CC=C2OCOC2=C1 WHAAPCGHVWVUEX-UHFFFAOYSA-N 0.000 claims description 9
- 230000000844 anti-bacterial effect Effects 0.000 claims description 8
- 239000003899 bactericide agent Substances 0.000 claims description 8
- 239000004562 water dispersible granule Substances 0.000 claims description 2
- 239000004563 wettable powder Substances 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000007900 aqueous suspension Substances 0.000 claims 1
- 230000000855 fungicidal effect Effects 0.000 claims 1
- 239000000417 fungicide Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000000361 pesticidal effect Effects 0.000 claims 1
- VABYUUZNAVQNPG-BQYQJAHWSA-N Piplartine Chemical compound COC1=C(OC)C(OC)=CC(\C=C\C(=O)N2C(C=CCC2)=O)=C1 VABYUUZNAVQNPG-BQYQJAHWSA-N 0.000 abstract description 8
- 230000002195 synergetic effect Effects 0.000 abstract description 8
- 238000011161 development Methods 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
- 206010059866 Drug resistance Diseases 0.000 abstract description 5
- 244000052616 bacterial pathogen Species 0.000 abstract description 3
- 239000003795 chemical substances by application Substances 0.000 description 13
- 239000003814 drug Substances 0.000 description 8
- 235000019510 Long pepper Nutrition 0.000 description 7
- 240000003455 Piper longum Species 0.000 description 7
- 150000001408 amides Chemical class 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 241001530056 Athelia rolfsii Species 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- 239000013043 chemical agent Substances 0.000 description 3
- 239000000447 pesticide residue Substances 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- 241000233866 Fungi Species 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 238000003912 environmental pollution Methods 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000010413 mother solution Substances 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241000219104 Cucurbitaceae Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 239000005782 Fluopicolide Substances 0.000 description 1
- 206010019799 Hepatitis viral Diseases 0.000 description 1
- 239000005794 Hymexazol Substances 0.000 description 1
- 241000243785 Meloidogyne javanica Species 0.000 description 1
- 241000218984 Momordica Species 0.000 description 1
- 235000009815 Momordica Nutrition 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241000758706 Piperaceae Species 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- JNVCSEDACVAATK-UHFFFAOYSA-L [Ca+2].[S-]SSS[S-] Chemical compound [Ca+2].[S-]SSS[S-] JNVCSEDACVAATK-UHFFFAOYSA-L 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- -1 carrier Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002888 effect on disease Effects 0.000 description 1
- GBOYJIHYACSLGN-UHFFFAOYSA-N fluopicolide Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CNC(=O)C1=C(Cl)C=CC=C1Cl GBOYJIHYACSLGN-UHFFFAOYSA-N 0.000 description 1
- FQKUGOMFVDPBIZ-UHFFFAOYSA-N flusilazole Chemical compound C=1C=C(F)C=CC=1[Si](C=1C=CC(F)=CC=1)(C)CN1C=NC=N1 FQKUGOMFVDPBIZ-UHFFFAOYSA-N 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 244000000004 fungal plant pathogen Species 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000004009 herbicide Substances 0.000 description 1
- KGVPNLBXJKTABS-UHFFFAOYSA-N hymexazol Chemical compound CC1=CC(O)=NO1 KGVPNLBXJKTABS-UHFFFAOYSA-N 0.000 description 1
- 230000028644 hyphal growth Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 201000001862 viral hepatitis Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P3/00—Fungicides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the technical field of pesticides, and particularly relates to a pesticide composition for preventing and treating Siraitia grosvenorii southern blight. The pesticide composition for preventing and treating Siraitia grosvenorii southern blight is compounded with Ningnan mycin, fluopyram or tebuconazole and piperlongumin as effective components. The pesticide composition provided by the invention has a synergistic effect on the Siraitia grosvenorii southern blight after being compounded, can improve the control effect, and can delay the generation and development of drug resistance of pathogenic bacteria.
Description
Technical Field
The invention belongs to the technical field of pesticides, and particularly relates to a pesticide composition for preventing and treating Siraitia grosvenorii southern blight.
Background
Momordica grosvenori is a vine plant of the Cucurbitaceae family. Momordica grosvenori is sweet and cool in taste and has great medicinal value besides edible value. The grosvenor momordica fruit is easily affected by diseases such as southern blight, root rot, root knot nematode, anthracnose and the like in the growth process. Wherein, the sclerotium rolfsii (Sclerotium rolfsii) can cause Siraitia grosvenorii southern blight (soil-borne disease), which mainly damages the basal part of stems, the diseased part is in a dark brown water-immersed spot, when serious, the surface grows white spun silk mycelium, and the surrounding surface spreads to be radial; in severe cases, the cortex of the stem decays exposing the xylem, leading to wilting and death of the whole plant.
At present, chemical agents such as lime sulfur, flusilazole, hymexazol and the like are still used as main agents for preventing and treating the southern blight of the momordica grosvenori. However, the long-term use of single chemical agent easily causes the generation and development of disease drug resistance, resulting in reduced prevention effect, and simultaneously, the environmental pollution and the exceeding of pesticide residues are easily caused, thus having the requirement of sustainable and healthy development of agricultural violations.
Piperlonguminide (CAS: 20069-09-4) is mainly present in the roots of Piper longum belonging to Piperaceae, and has the following molecular structural formula:
piperlongum amide has important medicinal value, including being used for treating viral hepatitis, stomach ache, tumor, bronchitis, diarrhea, respiratory tract infection, etc., wherein, the research of anti-tumor activity of piperlongum amide is most widely. In addition, the application of piperlonguminine in agriculture is disclosed in the prior art, and the application of piperlonguminine in preventing and controlling agricultural weed herbicides is disclosed in the patent of publication No. CN 113812412A; the patent of publication No. CN113826629A discloses the use of piperlonguminide for controlling plant pathogenic fungi; the patent publication No. CN113796379A discloses the use of piperlonguminine in bacterial diseases of steel plants.
Compounding or blending different pesticide varieties is an effective way for developing novel medicaments and preventing and treating resistant diseases. At present, no report on the compounding of Ningnanmycin, fluopyram or tebuconazole and piperlongumin is found.
The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person of ordinary skill in the art.
Disclosure of Invention
The invention aims to provide a pesticide composition for preventing and treating Siraitia grosvenorii southern blight, which solves the problems that the long-term use of a single variety of chemical agent easily causes the generation and development of disease drug resistance, causes the reduction of prevention effect, simultaneously easily causes the environmental pollution and the exceeding of pesticide residues, and has the requirement of sustainable and healthy development of agricultural violations.
In order to achieve the above purpose, the present invention provides the following technical solutions:
the pesticide composition for preventing and treating Siraitia grosvenorii southern blight is compounded with Ningnan mycin, fluopyram or tebuconazole and piperlongumin as effective components.
Preferably, the mass ratio of the ningnanmycin to the piperlongumin is 1-8:20-1.
Preferably, the mass ratio of fluopyram to piperlongumin is 1-35:25-1.
Preferably, the mass ratio of the tebuconazole to the piperlonguminine is 1-9:9-1.
The invention also provides a bactericide which is prepared from the pesticide composition and other auxiliary components; wherein, other auxiliary components can be one or more of dispersing agent, wetting agent, carrier, solvent, binder, disintegrating agent, defoaming agent, antifreezing agent, preservative, etc. in the prior art according to the formulation of the bactericide.
Preferably, the mass of the pesticide composition accounts for 0.5-80% of the total mass of the bactericide.
Preferably, the bactericide is in the form of wettable powder, water dispersible granules, suspending agent or water aqua.
Compared with the prior art, the invention has the following beneficial effects:
(1) The pesticide composition has good control effect on diseases such as Siraitia grosvenorii southern blight and the like caused by sclerotium rolfsii.
(2) The pesticide composition can reduce the dosage, thereby reducing the prevention and control cost and pesticide residue and reducing the pollution to the environment.
(3) The pesticide composition provided by the invention has a synergistic effect on the Siraitia grosvenorii southern blight after being compounded, can improve the control effect, and can delay the generation and development of drug resistance of pathogenic bacteria.
Detailed Description
The following description of the embodiments of the present invention will be apparent from, and is intended to provide a thorough description of, the embodiments of the present invention, and not a complete description of, the embodiments of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present invention without making any inventive effort, are intended to fall within the scope of the present invention.
Examples: screening of control agents
1. Test strain
Sclerotium rolfsii (Sclerotium rolfsii), isolated from diseased momordica grosvenori seedlings, was stored on PDA medium for later use.
2. Test agent
40% Ningnanmycin (Sichuan gold bead ecological agriculture technology Co., ltd.), 98% fluopyram (Bayer Co., ltd.), 97% tebuconazole (Shenyang chemical Co., ltd.), 97% Piperlongum longum amide (Shanghai Ala Biochemical technology Co., ltd.).
After the test agent is prepared into a single-agent mother solution, a plurality of groups of proportions are arranged, and each single-agent mother solution and the proportion mixture are provided with 5 mass concentration gradients according to an equal ratio method.
3. Test method
Hyphal growth rate method (Mu Liyi, 1994) was used. Sucking 1mL of the liquid medicine, mixing with 9mL of PDA culture medium melted and cooled to 50-55 ℃, pouring into a sterile culture dish with the diameter of 9cm, and preparing a medicine-containing flat plate with corresponding concentration; treatments without agent were included as blank, and 8 plates were set for each treatment. The center of each drug-containing plate and the blank control plate is inoculated with a test fungus cake with the diameter of 5mm, and the test fungus cake is placed at the constant temperature of 27 ℃ for culture after a dish cover is covered. When the diameter of the blank control colony reaches more than 2/3 of the diameter of the culture dish, measuring the colony diameter by a crisscross method, and calculating the growth inhibition rate of different treatments on hyphae.
4. Data analysis
Data statistics analysis is carried out by adopting DPS software to obtain a virulence regression equation of each single dose and the mixture and EC of each single dose and each mixture to test pathogens 50 Calculating co-toxicity coefficient (CTC) according to grand cloud Pel method, evaluating synergistic effect of the medicament according to calculated co-toxicity coefficient (CTC), wherein CTC is less than or equal to 80 and is antagonistic, CTC is less than or equal to 120 and is additive, CTC is more than or equal to 120 and is synergistic,
in the above formula: ati—the measured virulence index of the mixture; s- -EC of standard pharmaceutical agent 50 The unit is mg/L; m- -EC of mixture 50 The unit is mg/L.
TTI＝TI A ×P A +TI B ×P B
In the above: TTI- -theoretical toxicological index of the mixture; TI (TI) A -a toxicity index of the agent; p (P) A - -A the percentage of agent in the blend in percent (%); TI (TI) B -a toxicity index of the agent; p (P) B The percentage content of the agent in the mixture is shown as percentage (%).
In the above formula: ctc—co-toxicity coefficient; ati—actual measured virulence index of the mixture; tti—the theoretical toxicity index of the mixture.
5. Measurement results
The results are shown in tables 1-3.
Table 1 determination of indoor biological Activity of Ningnanmycin and Piper longum amide Complex against Momordica grosvenori southern blight
| Medicament name and ratio | EC50(mg/L) | ATI | TTI | CTC |
| Ningnan mycin | 17.329 | 100.000 | -- | -- |
| Piperlonguminide | 46.573 | 37.208 | -- | -- |
| Ningnanmycin 1: piperlonguminide 20 | 23.447 | 73.907 | 40.198 | 183.856 |
| Ningnanmycin 1: piperlonguminide 10 | 18.191 | 95.261 | 42.917 | 221.969 |
| Ningnanmycin 1: piperlonguminide 5 | 25.858 | 67.016 | 47.674 | 140.573 |
| Ningnanmycin 1: piperlonguminide 1 | 15.339 | 112.973 | 68.604 | 164.674 |
| Ningnanmycin 4: piperlonguminide 1 | 13.289 | 130.401 | 87.442 | 149.129 |
| Ningnanmycin 8: long pepperBolongamide 1 | 10.677 | 162.302 | 93.023 | 174.475 |
As can be seen from Table 1, after Ningnanmycin and piperlongumin are compounded, the mass ratio is 1-8: the co-toxicity coefficient of the momordica grosvenori and the southern blight germ is greater than 120 in the range of 20-1, and the synergistic effect is shown.
Table 2 determination of indoor Activity of Fluopyram and Piper longum amide Complex against Momordica grosvenori southern blight
| Medicament name and ratio | EC50(mg/L) | ATI | TTI | CTC |
| Fluopicolide | 2.581 | 100.000 | -- | -- |
| Piperlonguminide | 46.573 | 5.542 | -- | -- |
| Fluopyram 1: piperlonguminide 25 | 20.232 | 12.757 | 9.175 | 139.043 |
| Fluopyram 1: piperlonguminide 15 | 17.672 | 14.605 | 11.445 | 127.605 |
| Fluopyram 1: piperlonguminide 10 | 14.184 | 18.197 | 14.129 | 128.789 |
| Fluopyram 1: piperlonguminide 5 | 10.078 | 25.610 | 21.285 | 120.321 |
| Fluopyram 1: piperlonguminide 1 | 3.599 | 71.714 | 52.771 | 135.898 |
| Fluopyram 5: piperlonguminide 1 | 2.437 | 105.909 | 84.257 | 125.697 |
| Fluopyram 10: piperlonguminide 1 | 2.294 | 112.511 | 91.413 | 123.080 |
| Fluopyram 15: piperlonguminide 1 | 1.851 | 139.438 | 94.096 | 148.187 |
| Fluopyram 25: piperlonguminide 1 | 1.174 | 219.847 | 96.367 | 228.135 |
| Fluopyram 35: piperlonguminide 1 | 0.695 | 371.367 | 97.376 | 381.374 |
As shown in table 2, after fluopyram and piperlongumin are compounded, the mass ratio is 1-35: the co-toxicity coefficient of the momordica grosvenori and the southern blight germ is greater than 120 in the range of 25-1, and the synergistic effect is shown.
Table 3 indoor bioactivity assay of tebuconazole and piperlonguminine complex against siraitia grosvenorii southern blight
| Medicament name and ratio | EC50(mg/L) | ATI | TTI | CTC |
| Tebuconazole | 8.273 | 100.000 | -- | -- |
| Piperlonguminide | 46.573 | 17.764 | -- | -- |
| Tebuconazole 1: piperlonguminide 9 | 25.340 | 32.648 | 25.987 | 125.631 |
| Tebuconazole 1: piperlonguminide 7 | 19.144 | 43.215 | 28.043 | 154.101 |
| Tebuconazole 1: piperlonguminide 3 | 11.780 | 70.229 | 38.323 | 183.258 |
| Tebuconazole 1: piperlonguminide 1 | 8.819 | 93.809 | 58.882 | 159.317 |
| Tebuconazole 3: piperlonguminide 1 | 6.975 | 118.609 | 79.441 | 149.305 |
| Tebuconazole 7: piperlonguminide 1 | 4.725 | 175.090 | 89.720 | 195.151 |
| Tebuconazole 9: piperlonguminide 1 | 7.107 | 116.406 | 91.776 | 126.837 |
As can be seen from table 3, after tebuconazole and piperlonguminine are compounded, the mass ratio is 1-9: the co-toxicity coefficient of the Siraitia grosvenorii and the southern blight germ is greater than 120 in the range of 9-1, and the synergistic effect is shown.
In conclusion, after Ningnanmycin, fluopyram or tebuconazole are compounded with piperlongum amide, the synergistic effect on Siraitia grosvenorii southern blight is achieved, the control effect can be improved, and meanwhile, the generation and development of drug resistance of pathogenic bacteria can be delayed.
The foregoing descriptions of specific exemplary embodiments of the present invention are presented for purposes of illustration and description. It is not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain the specific principles of the invention and its practical application to thereby enable one skilled in the art to make and utilize the invention in various exemplary embodiments and with various modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims and their equivalents.
Claims (7)
1. The pesticide composition for preventing and treating the Siraitia grosvenorii southern blight is characterized in that the effective components are compounded by Ningnanmycin, fluopyram or tebuconazole and piperlonguminine.
2. The pesticide composition for preventing and treating southern blight of momordica grosvenori according to claim 1, wherein the mass ratio of Ningnanmycin to piperlonguminine is 1-8:20-1.
3. The pesticide composition for preventing and treating the southern blight of momordica grosvenori according to claim 1, wherein the mass ratio of fluopyram to piperlonguminum is 1-35:25-1.
4. The pesticide composition for preventing and treating southern blight of momordica grosvenori according to claim 1, wherein the mass ratio of tebuconazole to piperlonguminine is 1-9:9-1.
5. A fungicide characterized in that it is prepared from the pesticidal composition of claim 1 and other auxiliary ingredients.
6. The bactericide according to claim 5, characterized in that the mass of the pesticide composition is 0.5 to 80% of the total mass of the bactericide.
7. The bactericide according to claim 5, wherein the bactericide is in the form of wettable powder, water dispersible granule, suspension or aqueous solution.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310860186.7A CN117598315A (en) | 2023-07-13 | 2023-07-13 | Pesticide composition for preventing and treating Siraitia grosvenorii southern blight |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310860186.7A CN117598315A (en) | 2023-07-13 | 2023-07-13 | Pesticide composition for preventing and treating Siraitia grosvenorii southern blight |
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| Country | Link |
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| CN (1) | CN117598315A (en) |
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