CN117547476A - Tianshan Jimei repair nourishing face cream - Google Patents
Tianshan Jimei repair nourishing face cream Download PDFInfo
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- CN117547476A CN117547476A CN202210931293.XA CN202210931293A CN117547476A CN 117547476 A CN117547476 A CN 117547476A CN 202210931293 A CN202210931293 A CN 202210931293A CN 117547476 A CN117547476 A CN 117547476A
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/985—Skin or skin outgrowth, e.g. hair, nails
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine repairing and nourishing face cream, which comprises the following raw materials in percentage by mass: 0.5-5% of various traditional Chinese medicine extracts, 2-5% of nicotinamide, 70-80% of water, 2-6% of glycerin, 2-4% of betaine, 1-3% of propylene glycol, 0.1-0.5% of sodium hyaluronate, 1-3% of caprylic/capric triglyceride, 4-6% of hydrogenated polyisobutene, 1-3% of cetylstearyl alcohol, 0.1-0.5% of tocopheryl succinate, 0.2-0.5% of carbomer, 0.1-0.5% of triethanolamine, 0.1-1% of vitamin C, 0.01-0.04% of disodium edetate, 0.4-1% of phenoxyethanol, 0.05-0.1% of essence and the like. The face cream provided by the invention takes the 'mild and efficient' effect as the key point, integrates the principles of traditional Chinese medicine and ancient prescription, combines the natural extracts of the traditional Chinese medicinal materials in the road, and is supplemented with the restoration star-like component nicotinamide, so that the skin sensitive state can be quickly relieved, and the face cream has a powerful restoration effect. The face cream provided by the invention is wide in applicable crowd, and natural raw materials are nontoxic and nonirritating, so that daily demands of people can be met.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to research and preparation of traditional Chinese medicine face cream with repairing and nourishing effects.
Background
Many factors in life have a certain impact on our skin. Such as ultraviolet irradiation, polluted environment and bad emotion, too long wearing mask, etc., can cause different problems of our skin. For dry autumn and winter, the cream has high water content and is easy to be absorbed by skin, and is an indispensable single product in skin care products. The face cream with repairing and nourishing effects can repair damaged sebum membranes, can better ensure the health of the sebum membranes, and has better effects on improving redness and swelling, stinging and discomfort caused by skin sensitivity. The conventional face cream is mainly prepared from chemical components, and the face cream prepared from pure natural traditional Chinese medicines for repairing and nourishing is less.
The existing pure natural traditional Chinese medicine face cream has poor quality, and the selection of raw materials also has defects. The face cream provided by the invention integrates the ancient Chinese medicine prescription, and the dominant medicinal materials are compatible to improve the repairing and nourishing effects.
Therefore, the design of the traditional Chinese medicine repairing and nourishing face cream with natural and nontoxic raw materials and no stimulation is imperative.
The cornu Cervi Pantotrichum is young horn of Cervus Nippon Temminck (Cervus nippon Temminck) or Cervus Nippon Temminck (Cervus elaphus Linnaeus) of Cervus Nippon Temminck of Cervus of Vertebrata, and is a Jilin provincial medicine. The data show that the main components of the composition comprise polysaccharides, polypeptides, steroid compounds, polyamines and the like. The hairy antler is compatible with extracts of Xinjiang dominant medicines such as liquorice, lithospermum and the like, has the effects of repairing, resisting oxidation and resisting inflammation, and is supplemented with extracts of coptis chinensis, prepared rehmannia root, scutellaria baicalensis, angelica sinensis, lavender and purslane, so that the repairing and nourishing effects are enhanced.
Disclosure of Invention
(one) solving the technical problems
The technical problem to be solved by the invention is that most of daily facial creams for repairing and nourishing are chemical components or prepared by adding a little of traditional Chinese medicine extract, the effect is weak and the traditional Chinese medicine components are good and bad. The invention aims to provide a natural traditional Chinese medicine face cream which takes dominant traditional Chinese medicines as functional components and has good repairing and nourishing effects. The traditional Chinese medicine repairing and nourishing face cream provided by the invention is obtained through a large number of experiments by the inventor, the formula is based on the principle of compatibility of traditional Chinese medicine theory, and the repairing and nourishing effect is achieved by focusing on using natural animal and plant components, so that the damage to the skin caused by excessive chemical additives in the face cream is avoided.
The traditional Chinese medicine repairing and nourishing face cream provided by the invention is prepared by carefully selecting raw materials such as hairy antler, coptis chinensis, prepared rehmannia root, lithospermum, liquorice, baical skullcap root, chinese angelica, lavender, purslane extract, nicotinamide and the like according to a traditional Chinese medicine compatibility principle, and adopting methods such as orthogonal design and the like to obtain the optimal formula components. Wherein radix Arnebiae and Glycyrrhrizae radix are Xinjiang cortex Linderae medicinal materials, and the extract can be added to achieve antiinflammatory and tranquilizing effects, and strengthen skin barrier. Aiming at the problems of local red and swelling of skin and the like caused by wearing a mask at present, the former is combined with extracts of coptis chinensis, scutellaria baicalensis, purslane, angelica and the like, and plays a better role in resisting inflammation and relieving. The invention has the advantages that the compatibility of the pilose antler with the prepared rehmannia root and lavender extract can slow down skin aging, maintain skin activity and have mild effect.
Advantageous effects
The traditional Chinese medicine repairing and nourishing face cream is different from the conventional face cream, wherein a plurality of traditional Chinese medicine additives are added to repair skin barriers, inhibit excessive free radical generation, promote cell metabolism and improve repairing and nourishing effects. The material is a pure natural raw material, has few chemical additives, no toxic or side effect, no irritation, excellent repairing and nourishing effects, wide applicable crowd and capability of meeting the daily skin care requirements of people.
(II) technical scheme
In order to solve the technical problems, the technical scheme provided by the invention is as follows: a traditional Chinese medicine repairing and nourishing face cream comprises the following raw materials in percentage by mass: the phase A raw materials comprise 1-3% of caprylic/capric triglyceride, 1-3% of cetostearyl alcohol and 4-6% of hydrogenated polyisobutene; the phase B raw material comprises water balance, 2-6% of glycerol, 1-3% of propylene glycol, 0.1-0.5% of sodium hyaluronate, 0.01-0.04% of disodium ethylenediamine tetraacetate, 0.2-0.5% of carbomer and 2-4% of betaine; the C phase raw material comprises 0.1-0.5% of tocopheryl succinate, 0.1-0.5% of triethanolamine, 0.1-0.4% of stabilizer, 0.4-1% of phenoxyethanol and 0.05-0.1% of essence; the D phase raw material comprises 0.5-5% of various traditional Chinese medicine extracts (including 0.75% of licorice extract, 0.5% of coptis extract, 0.5% of pilose antler extract, 0.2% of lithospermum extract, 0.35% of angelica extract, 0.35% of purslane extract, 0.1% of radix scutellariae extract, 0.01% of prepared rehmannia root extract, 0.008% of lavender extract), 2-5% of nicotinamide and 0.1-1% of vitamin C.
The preparation method comprises the following steps:
s1, placing the phase A raw material into a water bath kettle at 75-80 ℃ and uniformly stirring for 30min until the phase A raw material is completely dissolved, thus obtaining a mixture A.
S2, adding other raw materials of the phase B after the carbomer is uniformly dispersed in water in advance, and then placing the mixture in a water bath kettle at 75-80 ℃ for uniform stirring for 30min until the phase B is completely dissolved, thus obtaining the mixture B.
S3, pouring the mixture B into the mixture A, uniformly mixing, then starting to reduce the speed and the temperature, adding the C-phase raw material when the temperature reaches 40-45 ℃, and heating and stirring to obtain the mixture C.
And S4, adding the D-phase raw material into the cooled mixture C, uniformly stirring until the cream texture is uniform and fine, and obtaining the repairing and nourishing cream.
Detailed Description
Embodiment one: traditional Chinese medicine repairing and nourishing face cream and performance test
According to the technical scheme, 6 traditional Chinese medicine repairing and nourishing face creams S1 to S6 are prepared.
To verify the eligibility of the traditional Chinese medicine repairing and nourishing cream, performance test is carried out on the cream.
Sensory performance assessment: taking a small amount of samples S1 to S6, and observing the appearance, color and aroma of the paste under daily illumination at room temperature.
And (3) testing the pH value: 2.0g of each of the S1 to S6 samples was weighed and uniformly dispersed with 30mL of distilled water at 40 ℃. The p H value of the aqueous solution was measured at room temperature using a calibrated p H meter.
Stability test: and respectively placing the S1 to S6 samples in a constant temperature oven at 48 ℃ for 24 hours, then transferring the samples into a refrigerator at minus 10 ℃ for 24 hours, and observing whether oil-water separation occurs in the samples.
The test result shows that the ointment is uniform and fine, the color is white to light brown, and the ointment has slight smell of Chinese herbal medicine; p H is in the range of 6.55-6.67; oil-free water separation phenomenon.
Embodiment two: traditional Chinese medicine repairing and nourishing face cream and efficacy evaluation
Since nourishing includes repair and moisturizing, in this example, repair efficacy evaluation of the face cream was mainly performed.
In vitro cell migration assay was performed: and (3) using fibroblasts, a 96-well plate, MTT, DMSO stock solution and the like, screening the intervention concentration of the active ingredients by using an MTT method, performing a cell scratch experiment, and finally calculating the healing rate.
The method for testing the epidermis model by adopting an in vitro recombination 3D skin test method comprises the following steps: the test needs to set a blank control group, a negative control group, a positive control group and a test object group for different administration treatments, and each group has 9 models. In ET50 assay 3 time points were set, 3 models were repeated for each time point, totaling 9 models. The absorbance (OD) was read at 570nm using isopropanol as a zeroing control. And finally, calculating the ET50 according to the test result.
Embodiment III: traditional Chinese medicine repairing and nourishing face cream and human body test
Selection of test personnel: according to the requirements of the face cream test, the testers are 30 healthy women (except for the lactation period of pregnancy) or men aged 20-40 years. No active allergic history, non-dermatological, was entered into other clinical trials within one month prior to the trial. According to the test requirement, the people with obvious skin injury phenomena such as red blood streak, skin redness, dryness and the like on the face and obvious fine lines on the skin are selected.
The standard patch test material is used for carrying out the patch test of human skin, and the dosage of each person is about 0.020g-0.025g. The patch test with the test substance was applied to the face of the subject with hypoallergenic tape, and applied to the skin uniformly for 24 hours. As a result, the skin lesions such as facial red blood streaks and redness of the subject were slightly improved.
The repeated open type smearing test is carried out, a proper amount of facial cream sample is smeared on the face of a subject, the tested part is kept dry, and the facial cream sample is uniformly smeared on the tested part twice a day for 7 continuous days. The skin reaction results were observed, and the facial redness of most subjects was significantly improved.
Experimental data can only represent an audience population of the age range of 20-40 years old, with limitations. Compared with the existing repairing and nourishing face cream in the market, the product has Chinese herbal medicine smell, and the color may not reach pure white.
Through the test, compared with the existing face cream, the face cream provided by the invention is natural traditional Chinese medicine repairing and nourishing face cream, local dominant medicinal materials are added, and various natural traditional Chinese medicines are mutually compatible, so that repairing and nourishing effects are improved. The extracts of the pilose antler, the baical skullcap root, the lithospermum, the liquoric root and the like are added, so that the skin care cream has the effects of anti-inflammatory, antioxidation, anti-aging and the like, and the effects of repairing and nourishing are enhanced, so that the daily skin care requirements of people are met.
Although the above embodiments have been described in detail, it should be understood that they are merely some, but not all embodiments of the invention, and that other embodiments can be obtained by equivalent variations or modifications without departing from the scope of the invention.
Claims (5)
1. A traditional Chinese medicine repairing and nourishing face cream is characterized by comprising a plurality of dominant medicinal materials for compatibility, and a plurality of skin conditioning agents are added to enhance repairing and nourishing effects.
2. The traditional Chinese medicine repair face cream of claim 1, wherein: the multi-place comprises dominant medicinal materials in Jilin, xinjiang, sichuan and Gansu areas, and the dominant medicinal materials are mainly the dominant medicinal materials.
3. The traditional Chinese medicine nourishing cream according to claim 1, wherein: the multiple advantageous medicinal materials comprise cornu Cervi Pantotrichum extract, coptidis rhizoma extract, radix rehmanniae Preparata extract, radix Arnebiae extract, glycyrrhrizae radix extract, scutellariae radix extract, radix Angelicae sinensis extract, lavender extract, and herba Portulacae extract.
4. The traditional Chinese medicine repairing and nourishing face cream according to claim 1, which is characterized in that: the skin conditioning agents include cornu Cervi Pantotrichum extract, coptidis rhizoma extract, radix rehmanniae Preparata extract, radix Arnebiae extract, glycyrrhrizae radix extract, scutellariae radix extract, radix Angelicae sinensis extract, lavender extract, herba Portulacae extract, nicotinamide, sodium hyaluronate, and vitamin C.
5. The traditional Chinese medicine repairing and nourishing face cream according to claim 1 is characterized by comprising the following preparation method:
s1, respectively weighing the phase A components with corresponding mass, and putting the phase A components into a water bath kettle with the temperature of 75-80 ℃ to be slowly stirred for about 30min until all the phase A components are dissolved, thus obtaining a mixture A.
S2, adding other raw materials of the phase B after the carbomer is uniformly dispersed in water in advance, and then placing the mixture in a water bath kettle at 75-80 ℃ for uniform stirring for about 30min until the phase B is completely dissolved, thus obtaining the mixture B.
S3, pouring the mixture B into the mixture A, uniformly mixing, then starting to reduce the speed and the temperature, adding the C-phase raw material when the temperature reaches 40-45 ℃, and heating and stirring to obtain the mixture C.
And S4, adding the phase D into the cooled mixture C, uniformly stirring until the cream texture is uniform and fine, and obtaining the repairing and nourishing cream.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210931293.XA CN117547476A (en) | 2022-08-04 | 2022-08-04 | Tianshan Jimei repair nourishing face cream |
| ZA2022/11761A ZA202211761B (en) | 2022-08-04 | 2022-10-28 | Tianshan jimei repairing and nourishing facial cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210931293.XA CN117547476A (en) | 2022-08-04 | 2022-08-04 | Tianshan Jimei repair nourishing face cream |
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| CN117547476A true CN117547476A (en) | 2024-02-13 |
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|---|---|---|---|
| CN202210931293.XA Pending CN117547476A (en) | 2022-08-04 | 2022-08-04 | Tianshan Jimei repair nourishing face cream |
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| Country | Link |
|---|---|
| CN (1) | CN117547476A (en) |
| ZA (1) | ZA202211761B (en) |
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2022
- 2022-08-04 CN CN202210931293.XA patent/CN117547476A/en active Pending
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| ZA202211761B (en) | 2023-02-22 |
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