CN117482385A - Electrode patch and tumor electric field treatment system - Google Patents
Electrode patch and tumor electric field treatment system Download PDFInfo
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- CN117482385A CN117482385A CN202311589199.1A CN202311589199A CN117482385A CN 117482385 A CN117482385 A CN 117482385A CN 202311589199 A CN202311589199 A CN 202311589199A CN 117482385 A CN117482385 A CN 117482385A
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- 230000005684 electric field Effects 0.000 title claims abstract description 77
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 51
- 230000026683 transduction Effects 0.000 claims abstract description 51
- 238000010361 transduction Methods 0.000 claims abstract description 51
- 239000000758 substrate Substances 0.000 claims abstract description 29
- 239000000853 adhesive Substances 0.000 claims description 21
- 230000001070 adhesive effect Effects 0.000 claims description 21
- 238000002560 therapeutic procedure Methods 0.000 claims description 9
- 239000011159 matrix material Substances 0.000 claims description 5
- 239000000919 ceramic Substances 0.000 description 60
- 238000003466 welding Methods 0.000 description 12
- 238000010586 diagram Methods 0.000 description 9
- 238000000034 method Methods 0.000 description 6
- 230000008054 signal transmission Effects 0.000 description 6
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- 239000000463 material Substances 0.000 description 3
- 230000003014 reinforcing effect Effects 0.000 description 3
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- 230000011278 mitosis Effects 0.000 description 2
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- 238000001959 radiotherapy Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 210000004881 tumor cell Anatomy 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 201000010915 Glioblastoma multiforme Diseases 0.000 description 1
- 102000004243 Tubulin Human genes 0.000 description 1
- 108090000704 Tubulin Proteins 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
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- 238000011109 contamination Methods 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- 208000006178 malignant mesothelioma Diseases 0.000 description 1
- 201000005282 malignant pleural mesothelioma Diseases 0.000 description 1
- 230000000394 mitotic effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
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- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0492—Patch electrodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/048—Electrodes characterised by a specific connection between lead and electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0488—Details about the lead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Electrotherapy Devices (AREA)
Abstract
The invention provides an electrode patch and a tumor electric field treatment system. Each electrode unit comprises a flexible board substrate, a transduction piece and a male seat, wherein the transduction piece and the male seat are respectively arranged at two opposite ends of the flexible board substrate and are electrically connected with each other; the adapter plate is provided with a body and a plurality of female seats, and a plurality of female seats are arranged on the body at intervals. One end of the electrode unit, which is provided with a male seat, is clamped between the adapter plate and the backing, and one end of the electrode unit, which is provided with the transduction piece, is exposed out of the adapter plate through a hollowed-out hole or a space on the body, and the male seat is in plug-in fit with the female seat. The adapter plate is provided with a second AC line, and the plurality of transduction plates are connected to the second AC line in parallel. The electrode patch of the tumor electric field treatment system realizes the detachable arrangement of a plurality of electrode units through the arrangement of the adapter plate, is convenient for replacing the damaged electrode units, and can reduce the treatment cost of patients.
Description
Technical Field
The application relates to an electrode patch and a tumor electric field treatment system, and belongs to the technical field of medical appliances.
Background
At present, the treatment modes of tumors mainly comprise operation, radiotherapy, chemotherapy and the like, but have corresponding defects, such as side effects caused by radiotherapy and chemotherapy, and normal cells can be killed. The use of electric fields to treat tumors is also one of the leading edges of current research and development, and tumor electric field treatment generates a tumor treatment method by using a special electric field generator to interfere with the mitotic progress of tumor cells through low-intensity, medium-high-frequency and alternating electric fields. Research shows that the electric field treatment has obvious effect in treating glioblastoma, non-small cell lung cancer, malignant pleural mesothelioma and other diseases, and the electric field applied by the treatment method can influence the aggregation of tubulin, prevent spindle body formation, inhibit mitosis process and induce cancer cell apoptosis.
The tumor electric field treatment system for treating tumor mainly comprises an electric field generator and electrode patches electrically connected with the electric field generator, wherein the electrode patches are applied to the skin of a human body in pairs, and an alternating electric field is applied to focus of the human body for alternating electric field treatment. Each electrode patch comprises a flexible circuit board, a plurality of ceramic plates arranged on the flexible circuit board at intervals and a lead electrically connected with the flexible circuit board, as disclosed in Chinese patent publication No. 11271272 or 113164745. The flexible circuit board comprises a flexible board substrate, a plurality of conductive traces embedded in the flexible board substrate and a plurality of conductive pads exposed on the flexible board substrate and electrically connected with the same conductive trace. The ceramic plates are welded with the corresponding conductive plates and arranged on the flexible circuit board, and are further connected in series through a path of conductive trace electrically connected with all the conductive plates. One end of the lead is electrically connected with the flexible circuit board, and the other end of the lead is provided with a plug which can be spliced with the electric field generator.
Because the ceramic plate is hard material and the flexible circuit board is flexible material, the flexible circuit board of the electrode patch of the tumor electric field treatment system has stronger mechanical strength at the positions where a plurality of ceramic plates are arranged at intervals than at the positions where the ceramic plates are not arranged, and further the flexible circuit board is easy to bend at the joint of the positions where the ceramic plates are arranged and the positions where the ceramic plates are not arranged, and the risk of breakage of the conductive traces in the flexible circuit board matrix is also caused if the bending is serious. The plurality of ceramic plates of the electrode patch are connected in series through the same conductive trace of the flexible circuit board, and the problems that the electric signal for tumor electric field treatment cannot be transmitted to all the ceramic plates due to the breakage of the conductive trace of the flexible circuit board, so that the electrode patch cannot apply an alternating electric field to the tumor part of a patient to perform tumor electric field treatment, the electrode patch cannot be used, the product manufacturing yield is low and the manufacturing cost is increased can exist.
Therefore, there is a need to provide an improved electrode patch and a tumor electric field therapy system, which solve the technical problems of the electrode patch of the tumor electric field therapy system.
Disclosure of Invention
The invention provides an electrode patch capable of improving stability of an electric signal for tumor electric field treatment and a tumor electric field treatment system.
Aiming at the problems existing in the prior art, the electrode patch provided by the invention is realized by the following technical scheme: an electrode patch for tumor electric field treatment comprises a plurality of electrode units, an adapter plate formed by a flexible circuit board and a back lining, wherein the electrode units and the adapter plate are adhered to the back lining, each electrode unit comprises a flexible board matrix, a transduction piece and a male seat, and the transduction piece and the male seat are respectively arranged at two opposite ends of one side surface of the flexible board matrix, which is far away from the back lining, and are electrically connected with each other; the adapter plate is provided with a body and a plurality of female seats, the female seats are arranged on the body at intervals, and the body is provided with hollowed holes or intervals; the electrode unit is provided with a plurality of electrode units, one end of each electrode unit is provided with a male seat, one end of each electrode unit is clamped between the adapter plate and the backing, one end of each electrode unit is provided with a replaceable energy piece, the adapter plate is exposed out through the hollow hole or the interval, the male seats are inserted with the corresponding female seats so that the plurality of electrode units are detachably and electrically connected to the adapter plate, a second AC line for transmitting alternating electric signals is embedded in the adapter plate, and the plurality of energy pieces are connected to the second AC line in parallel through the electrical connection of the male seats and the female seats.
Further, the body is provided with a trunk and a plurality of branches positioned at two sides of the trunk, the plurality of female seats are distributed on the trunk and the branches, and the interval is arranged between two adjacent branches positioned at the same side of the trunk.
Furthermore, the trunk is provided with the hollowed-out hole.
Further, the electrode unit further comprises a temperature sensor arranged on the flexible board substrate, the transduction piece is provided with a penetrating hole for accommodating the temperature sensor, the temperature sensor is provided with a grounding end and a signal end, one path of second grounding wires and multiple paths of parallel second signal wires are embedded in the adapter plate, the grounding ends of the electrode units are connected in parallel to the second grounding wires through the electrical connection of the male base and the female base, and the signal ends of the electrode units are connected with the corresponding second signal wires through the electrical connection of the male base and the female base.
Further, the second AC line and the second grounding line are all arranged in a dendritic wiring mode.
Further, the adapter plate further comprises a wire, the adapter plate is provided with a wiring part connected with one end of the body, the surfaces of two sides of the wiring part are provided with a plurality of fourth bonding pads welded with the wire, the fourth bonding pads comprise a plurality of conducting bonding pads, and the conducting bonding pads are electrically connected with the corresponding second AC wire, second grounding wire or second signal wire.
Further, at least one dummy pad is further included in the fourth pads, and none of the dummy pads is electrically connected to the second AC line, the second ground line, and the second signal line.
Further, the backing is provided in a sheet shape and has a plurality of through holes exposing a plurality of the electrode units.
Further, the electrode unit comprises a support member and an adhesive member, wherein the support member is arranged around the corresponding parts of the electrode units and adhered to the back lining, the adhesive member covers the support member and the electrode units, and the support member is provided with a first perforation for accommodating the electrode units and a second perforation arranged among the first perforation.
The tumor electric field treatment system provided by the invention is realized by the following technical scheme: an electric field tumor therapeutic system comprises an electric field generator and at least one pair of electrode patches electrically connected with the electric field generator.
The electrode patch of the tumor electric field treatment system is formed by detachably connecting the electrode units with the adapter plate, and the electrode units are connected to the adapter plate in parallel, so that the AC signals of the electrode units are not affected by each other, even if the electrode units are damaged in the use process, the other electrode units are not affected to continuously apply an alternating electric field to the tumor part of a patient for tumor electric field treatment, the stability of electric signals of tumor electric field treatment is improved, and the treatment cost of the patient can be reduced to a certain extent.
Drawings
FIG. 1 is a schematic diagram of an electrode patch of a tumor electric field therapy system according to the present invention;
FIG. 2A is an exploded view of the electrode unit of FIG. 1;
FIG. 2B is a schematic diagram of the electrode unit of FIG. 1;
FIG. 3 is a wiring diagram of a flexible board base of the electrode unit of FIG. 2A;
fig. 4 is a schematic structural diagram of the interposer of fig. 1;
fig. 5A is a front wiring diagram of the interposer of fig. 4;
FIG. 5B is a reverse wiring diagram of the interposer of FIG. 4;
FIG. 6A is a schematic diagram of a front side combination of the electrode unit, interposer, wires and backing of FIG. 1;
FIG. 6B is a schematic view of the reverse side combination of the electrode unit, interposer, wires, and backing of FIG. 1;
FIG. 7 is a schematic diagram of the electrode unit, interposer, wire, backing, and support combination of FIG. 1;
FIG. 8A is a front side assembled schematic view of the electrode patch of FIG. 1;
FIG. 8B is a schematic view of the electrode patch of FIG. 1 from another perspective;
fig. 9 is a schematic diagram of a tumor electric field therapy system according to the present invention.
Detailed Description
Reference will now be made in detail to exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, the same numbers in different drawings refer to the same or similar elements, unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present application. Rather, they are merely examples of apparatus, devices, and systems that are consistent with aspects of the present application as detailed in the accompanying claims.
Fig. 1 to 9 show a tumor electric field treatment system 1000 according to the present invention, which includes an electric field generator 200 and an electrode patch 100 connected to the electric field generator 200. The electrode patch 100 is applied to the skin surface of the human body, and the therapeutic electric field generated by the electric field generator 200 is applied to the human body to perform tumor electric field therapy. The electrode patch 100 of the embodiment of the present application is applied to the head of a human body for assisting in treating brain tumors, such as glioblastoma multiforme. In other embodiments, an adapter 300 may also be provided between the electrode patch 100 and the electric field generator 200 of the tumor electric field therapy system 1000. The adapter 300 is electrically connected between the electrode patch 100 and the electric field generator 200.
Fig. 1 to 8 show an electrode patch 100 according to an embodiment of the present invention. The electrode patch 100 may be directly plugged into the electric field generator 200 to electrically connect with the electric field generator 200, or may be directly plugged into the adapter 300 to electrically connect with the electric field generator 200 via the adapter 300, so as to electrically connect with the electric field generator 200. The electrode patch 100 includes at least one electrode unit 10, an adapter plate 20 detachably connected to the at least one electrode unit 10, a lead 30 electrically connected to the adapter plate 20, a backing 40 attached to respective portions of the electrode unit 10 and the adapter plate 20, a support member 50 surrounding the respective portions of the electrode unit 10 and attached to the backing 40, and an adhesive member 60 covering the support member 50 and the respective portions of the electrode unit 10 and adhering to the body surface skin corresponding to the tumor site of the patient. The electrode patch 100 is attached to the body surface corresponding to the tumor site of the patient through the backing 40, and an alternating electric field is applied to the tumor site of the patient through at least one electrode unit 10 detachably connected with the adapter plate 20 to interfere or prevent the mitosis of tumor cells of the patient, thereby achieving the purpose of treating tumors. The electrode patch 100 is formed by detachably connecting at least one electrode unit 10 and the adapter plate 20, so that the electrode unit 10 with failure can be detachably replaced or the adapter plate 20 with failure can be detachably replaced, the loss of the whole electrode patch 100 can be reduced before the product is delivered, the yield loss of the electrode patch 100 is reduced, the scrapping of the whole electrode patch 100 can be avoided when the electrode patch 100 is used, and the cost is saved; the intensity of the alternating electric field applied by the electrode patch 100 can also be adaptively adjusted according to the tumor size by freely selecting the number of electrode units 10 plugged onto the adapter plate 20.
Referring to fig. 2A and 2B, each electrode unit 10 includes a flexible board base 11, support plates 13 and ceramic transduction plates 12 respectively disposed at both sides of the flexible board base 11, and a male base 15 disposed at the same side surface of the flexible board base 11 as the ceramic transduction plates 12. The ceramic transduction piece 12 and the male seat 15 are respectively positioned at two opposite ends of the flexible board substrate 11, and the ceramic transduction piece 12 and the supporting plate 13 are positioned at the same end of the flexible board substrate 11. In this embodiment, the dimensions of the support plate 13 and the ceramic transduction piece 12 are slightly smaller than those of the flexible plate substrate 11.
The ceramic transducer sheet 12 is made of a high dielectric constant material, and has conductive properties that prevent the conduction of direct current and allow the passage of alternating current, so that the safety of users can be ensured during tumor electric field treatment. The ceramic transduction sheet 12 has a through-hole 121 at its center. The electrode unit 10 further includes a temperature sensor 14 provided on the flexible board base 11 and located on the same side as the ceramic transduction sheet 12. The temperature sensor 14 is accommodated in the opening 121 in the center of the ceramic transduction sheet 12 to sense the temperature of the skin of the patient to which the electrode patch 100 is applied. The temperature sensor 14 has a ground terminal 14A and a signal terminal 14B. Preferably, the temperature sensor 14 is a thermistor.
Referring to fig. 3, the flexible board base 11 is embedded with three first conductive traces 114. The three first conductive traces 114 include a first ground line 114A electrically connected to the ground end 14A of the temperature sensor 14 and the male base 15, a first signal line 114B electrically connected to the signal end 14B of the temperature sensor 14 and the male base 15 for transmitting a temperature signal, and a first AC line 114C disposed in a ring shape and electrically connected to the ceramic transducer 12 and the male base 15. The first ground line 114A and the first signal line 114B are each extended in the longitudinal direction of the flexible board substrate 11. The first AC line 114C is annularly disposed along the periphery of the flexible board substrate 11 and is in a two-section structure electrically connected end to end at the location of the flexible board substrate 11 where the male seat 15 is disposed, that is, the male seat 15 is electrically connected with the ceramic transduction piece 12 through two sections of lines, so when one section of the first AC line 114C is broken due to bending, an electrical signal can be transmitted to the ceramic transduction piece 12 through the other section of the first AC line 114C, thereby ensuring the electrical reliability of the electrode unit 10, improving the product quality and reducing the defective rate of the product. The first ground line 114A and the first signal line 114B are both located inside the annular first AC line 114C, so as to facilitate wiring and reduce wiring difficulty.
Specifically, the first AC line 114C is disposed along the periphery of the flexible board substrate 11 in a sealed ring shape, and includes a first AC line segment 115 disposed at the same end as the ceramic transduction piece 12 in a circular arc shape, and a second AC line segment 116 extending from the first AC line segment 115 and disposed in an inverted "n" shape. The first AC line segment 115 is electrically connected to the ceramic transduction sheet 12 disposed on the flexible board substrate 11. One end of the first AC line segment 116 is connected to opposite ends of the first AC line segment 115, and the other end is welded to the male socket 15 provided on the flexible board base 11. The electrode unit 10 is electrically connected with the first AC line segment 115 of the first AC line 114C of the flexible board substrate 11 through the ceramic transduction piece 12, one end of the first AC line segment 115 of the first AC line 114C of the flexible board substrate 11 is connected with the second AC line segment 116, and the other end of the second AC line segment 116 of the first AC line 114C of the flexible board substrate 11 is electrically connected with the male socket 15, so that the electrical connection between the ceramic transduction piece 12 and the male socket 15 is realized.
The second AC line segment 116 is closed at an end far from the first AC line segment 115 after extending from opposite ends of the first AC line segment 115 along the length direction of the flexible board base 11, respectively. The second AC line segment 116 extends from one end of the first AC line segment 115 toward a direction away from the ceramic transduction piece 12, then bends and extends toward the other end of the first AC line segment 115, and then extends toward the other end of the first AC line segment 115 until being connected to the other end of the first AC line segment 115. The second AC line segment 116 includes a portion extending from one end of the first AC line segment 115 and having an "L" configuration and a portion extending from the other end of the first AC line segment 115 and having an "I" configuration. The second AC line segment 116 has two parts respectively connected to two opposite ends of the first AC line segment 115, and can be connected to the other end of the first AC line segment 115 through the other part thereof when one part thereof is disconnected from the one end of the first AC line segment 115 due to bending, so as to ensure the electrical connection between the second AC line segment and the first AC line segment 115, thereby realizing good and stable electrical connection between the ceramic transducer 12 and the male base 15. That is, the second AC line segment 116 of the first AC line 114C is connected to opposite ends of the arc-shaped first AC line segment 115 at the same time, and even when one end of the second AC line segment 116 and the first AC line segment 115 is disconnected by bending, an electrical signal can be transmitted to the ceramic transduction piece 12 through the connection between the second AC line segment 116 and the other end of the first AC line segment 115, so that the reliability of the electrical connection between the ceramic transduction piece 12 of the electrode unit 10 and the flexible board substrate 11 is ensured, the product quality is improved, and the product reject ratio is reduced. The first ground line 114A and the first signal line 114B are both located in the area surrounded by the first AC line 114C, so as to facilitate wiring and reduce wiring difficulty.
The same side surface of the flexible board substrate 11 is also provided with a plurality of conductive pads 111 which are arranged at intervals and welded with the ceramic transduction piece 12, two first bonding pads 112 which are respectively welded with the grounding end 14A and the signal end 14B of the temperature sensor 14, and a plurality of second bonding pads 113 which are welded with the male base 15. The conductive pad 111 and the first pad 112 are both positioned at the same end of the flexible board base 11, and the second pad 113 is positioned at the other end of the flexible board base 11. The plurality of conductive plates 111 are respectively electrically connected with the first AC line segments 115 of the first AC lines 114C embedded in the flexible board substrate 11, and are connected in series through the arc-shaped first AC line segments 115. The flexible board substrate 11 is electrically connected with the conductive disc 111 through the first AC line segment 115 of the first AC line 114C, and the conductive disc 111 is welded with the ceramic transduction piece 12 to realize the electrical connection between the conductive disc and the ceramic transduction piece 12.
The two first pads 112 are located at intermediate positions surrounded by the plurality of conductive pads 111. The first pad 112 soldered to the ground terminal 14A of the temperature sensor 14 is a first pad 112A, and the first pad 112 soldered to the signal terminal 14B of the temperature sensor 14 is a first pad 112B. The first pad 112A is disposed at an end of the first ground line 114A within the first AC line segment 115 of the first AC line 114C, and the first pad 112B is disposed at an end of the first signal line 114B within the first AC line segment 115 of the first AC line 114C. The first pad 112A is electrically connected to an end of the first ground line 114A, and the first pad 112B is electrically connected to an end of the first signal line 114B. The flexible board substrate 11 is electrically connected with the temperature sensor 14 by welding the grounding end 14A of the temperature sensor 14 through the first bonding pad 112A connected with the first grounding wire 114A and welding the signal end 14B of the temperature sensor 14 through the first bonding pad 112B connected with the first signal wire 114B.
The second pads 113 and the first pads 112 are respectively provided at opposite ends of the flexible board base 11. The second bonding pad 113 is disposed at one end of the flexible board substrate 11 far away from the ceramic transduction piece 12 and is welded with the male seat 15, so as to realize electrical connection with the male seat 15. The at least 3 second pads 113 include a second pad 113A electrically connected to the first pad 112A through the first ground line 114A, a second pad 113B electrically connected to the first pad 112B through the first signal line 114B, and at least one second pad 113C electrically connected to the conductive pad 111 through the first AC line 114. The second bonding pad 113A and the first bonding pad 112A are respectively disposed at two opposite ends of the first ground line 114A, and are electrically connected through the first ground line 114A. The second bonding pad 113B and the first bonding pad 112B are respectively disposed at two opposite ends of the first signal line 114B, and are electrically connected in time through the first signal line 114B. The second pads 113C and the conductive pads 111 are respectively disposed at opposite ends of the first AC line 114, and electrically connected to each other through the first AC line 114. The second pad 113C is disposed at an end of the second AC line segment 116 of the first AC line 114, and the conductive pad 111 is disposed on the first line segment 115 of the first AC line 114. The flexible board substrate 11 is welded with the ceramic transduction piece 12 through the conductive disc 111 arranged on the first AC line segment 115 of the first AC line 114C, and the second bonding pad 113C arranged at the tail end of the second line segment 116 of the first AC line 114C is welded with the male seat 15, so that the electrical connection between the male seat 15 and the ceramic transduction piece 12 is realized. The flexible board substrate 11 is welded with the grounding end 14A of the temperature sensor 14 through a first bonding pad 112A arranged at one end of the first grounding wire 114A, a first bonding pad 112B arranged at one end of the first signal wire 114B is welded with the signal end 14B of the temperature sensor 14, a second bonding pad 113A arranged at the other end of the first grounding wire 114A and a second bonding pad 113B arranged at the other end of the first signal wire 114B are welded with the male seat 15, so that the electrical connection between the temperature sensor 14 and the male seat 15 is realized.
At least three second bonding pads 113 are welded with the male base 15, so that the male base 15 and the flexible board base 11 can be firmly welded when the male base 15 is welded to the flexible board base 11 through the second bonding pads 113, and good electrical connection between the male base 15 and the flexible board base 11 is ensured. And the conductive plate 111 is welded to the male socket 15 through at least one second bonding pad 113C disposed on the second AC line segment 116 of the first AC line 114C, so as to ensure stable electrical connection between the conductive plate 111 and the male socket 15, so that an electrical signal for tumor therapy is transmitted to the conductive plate 111 through the first AC line 114C, and then transmitted to the ceramic transducer 12 through the conductive plate 111. In this embodiment, the four second pads 113C soldered to the male socket 15 are respectively connected to the second AC line segments 116 of the first AC line 114C. Other embodiments are possible for the purpose of achieving the weld tightness between the reinforcing male socket 15 and the flexible board base 11. For example, one of the plurality of second pads 113 is connected to the first ground line 114A, one of the second AC line segments 116 connected to the first AC line 114C, and the remaining ones are connected to the corresponding first signal lines 114B in one-to-one correspondence, respectively. For another example, one of the plurality of second pads 113 is connected to the first signal line 114B, one is connected to the first AC line 114C, and the remaining is connected to the first ground line 114A, respectively. That is, two of the plurality of second pads 113 are connected to two lines of the first ground line 114A, the first signal line 114B, and the first AC line 114C, respectively, and the remaining second pads 113 are connected to the remaining one lines of the first ground line 114A, the first signal line 114B, and the first AC line 114C.
The grounding signal of the temperature sensor 14 is transmitted to the corresponding second bonding pad 113A electrically connected with the first grounding wire 114A through the first grounding wire 114A electrically connected with the grounding end 14A; the temperature signal detected by the temperature sensor 14 is transmitted to the corresponding second bonding pad 113B electrically connected to the first signal line 114B through the first signal line 114B electrically connected to the signal end 14B; and the temperature signal detected by the temperature sensor 14 is transmitted to the electric field generator 200 through the welding of the second welding pad 113 and the male seat 15, the plugging of the male seat 15 and the adapter plate 20, the electric connection of the adapter plate 20 and the lead 30 and the plugging of the lead 30 and the electric field generator 200, so that the purpose that the electric field generator 200 controls the alternating electric signal transmitted to the ceramic transduction piece 12 through the detected temperature signal to avoid the low-temperature scalding of the tumor body surface of a patient caused by overhigh temperature is achieved. The AC signal generated by the electric field generator 200 is transmitted to the first AC line 114C disposed in a ring shape through the corresponding at least two second bonding pads 113C, and then transmitted to the ceramic transduction sheet 12 through the plurality of conductive pads 111 welded to the first AC line 114C, so as to apply the AC electric signal to the tumor site for tumor electric field treatment. The AC signal required for the ceramic transduction sheet 12 is an alternating current signal, which is output by the electric field generator 200. The electric field generator 200 also outputs a direct current signal to the temperature sensor 14, which causes the temperature sensor 14 to be connected to a ground signal and operate to generate a temperature signal.
The support plate 13 is adhered to a side surface of the flexible plate base 11 remote from the conductive plate 111 by an adhesive (not shown). The support plates 13 are in one-to-one correspondence with the ceramic transduction plates 12 in the thickness direction. The temperature sensor 14 is welded at the positions of the flexible board substrate corresponding to the two first bonding pads 112, the ceramic transduction piece 12 is welded at the positions of the flexible board substrate 11 corresponding to the plurality of conductive plates 111, and the male seat 15 is welded at the position of the second bonding pad 113 of the flexible board substrate 11. The temperature sensor 14, the ceramic transduction piece 12 and the supporting plate 13 are all arranged at the same end of the flexible plate base body 11. When the temperature sensor 14 and the ceramic transduction piece 12 are welded, the supporting plate 13 provides strength support for the flexible plate base 11, provides a flat welding plane for welding operation between the flexible plate base 11 and the temperature sensor 14 and the ceramic transduction piece 12, and improves the product yield. The stiffening plate 16 is stuck and arranged at one end of the flexible board base 11, which is positioned at the welded male base 15, the stiffening plate 16 is arranged on the surface of one side of the flexible board base 11, which is opposite to the male base 15, so as to provide strength support for the flexible board base 11, so that the male base 15 is welded on the stiffening plate base, and meanwhile, the situation that the welding part of the flexible board base 11 and the male base 15 bends when the male base 15 of the electrode unit 10 is plugged and unplugged with the adapter plate 20 is avoided, so that the conductive trace embedded in the flexible board base 11 is broken. The reinforcing plate 16 and the male seat 15 are respectively arranged on two opposite sides of the flexible board base 11. The reinforcing plate 16 and the male seat 15 are positioned at the same end of the flexible board base 11.
The adapter plate 20 is provided with at least one female seat 25 corresponding to and electrically connected with the male seat 15 of the electrode unit 10. The electrode patch 100 with at least one electrode unit 10 can be formed by plugging and combining the plurality of electrode units 10 with the corresponding female seats 25 on the adapter plate 20 through the corresponding male seats 15, and the electrode unit 10 and the adapter plate 20 can be detachably combined, so that the electrode unit 10 with failure can be detachably replaced, or the adapter plate 20 with failure can be detachably replaced, the scrapping of the whole electrode patch 100 is avoided, and the yield loss of the electrode patch 100 is reduced; the whole electrode patch 100 is prevented from being scrapped, waste is avoided, and the cost is reduced; meanwhile, the number of the electrode units 10 inserted onto the adapter plate 20 can be freely combined and selected to increase or decrease the electric field intensity generated by the electrode patch 100, so as to ensure that the electrode patch 100 generates the electric field intensity of the required size of the tumor part of the patient.
The adapter plate 20 is in a sheet-like arrangement and has a body 28 for plugging and combining at least one electrode unit 10 and a connection portion 27 for electrically connecting with a lead 30. The wire connection portion 27 is integrally provided with the body 28. The wire connection portion 27 is located at one side end of the body 28. The female socket 25, which is inserted into the male socket 15 of the electrode unit 10, is provided on the body 28 by welding. The lead 30 is electrically connected to the interposer 20 by soldering with the wiring portion 27. The electrode unit 10 of the electrode patch 100 is connected with the adapter plate 20 through the male seat 15 and the female seat 25 welded on the adapter plate 20 in an inserting manner, and the adapter plate 20 is connected with the lead 30 through the wiring portion 27 and the lead 30 in an electric manner. The electrode unit 10 of the electrode patch 100 is electrically connected to the lead 30 through the interposer 20. Preferably, the interposer 20 is a flexible circuit board. Preferably, the plurality of electrode units 10 are all connected to the interposer 20 in parallel, and even if the electrical connection between one electrode unit 10 and the interposer 20 is interrupted, the electrical connection between the rest of the electrode units 10 and the interposer 20 is not affected.
Referring to fig. 5A and 5B, the interposer 20 has at least one set of third pads 23 disposed on the body 28 and soldered to the corresponding female sockets 25, and a plurality of fourth pads 24 disposed on opposite sides of the wiring portion 27 and soldered to the wires 30. The configuration of each group of third pads 23 is the same as that of the second pads 113 of the electrode unit 10, each group of third pads 23 has a plurality of third pads 23, one third pad 23A of the plurality of third pads 23 is connected to a ground signal, one third pad 23B is connected to a temperature signal, and the remaining third pads 23C are connected to an AC signal. A set of fourth pads 24 has a plurality of fourth pads 24. The fourth pads 24 include a fourth pad 24A transmitting a ground signal, a fourth pad 24C transmitting an AC signal, and a plurality of fourth pads 24B transmitting respective temperature signals. The third pads 23A transmitting the ground signal among the plurality of sets of third pads 23 are each connected in parallel to one fourth pad 24A, the plurality of third pads 23C transmitting the AC signal among the plurality of sets of third pads 23 are each connected in parallel to one fourth pad 24C, and the third pads 23B transmitting the temperature signal among the plurality of sets of third pads 23 are each connected to the corresponding fourth pad 24B.
The interposer 20 has embedded therein a plurality of second conductive traces 26. The third pads 23 and the fourth pads 24A, 24B, and 24C are respectively disposed at two opposite ends of the multiple second conductive traces 26, and are electrically connected with each other through the second conductive traces 26. The plurality of groups of third bonding pads 23 are arranged at one end of the plurality of second conductive traces 26 in parallel, and the plurality of electrode units 10 can be connected to the adapter plate 20 in parallel after the plurality of electrode units 10 are respectively inserted into the female sockets 25 welded with the plurality of groups of third bonding pads 23 through the corresponding male sockets 15, so that signal transmission between each electrode unit 10 and the adapter plate 20 is independent and is not affected by each other, and even if one electrode unit 10 is damaged, signal transmission between the rest electrode units 10 and the adapter plate 20 is not affected, and normal operation of the rest electrode units 10 is ensured without replacing or scrapping the whole electrode patch 100.
The multiplexed second conductive trace 26 includes a second ground line 26A that transmits a ground signal, a second AC line 26C that transmits an AC signal, and a second signal line 26B that transmits a corresponding temperature signal, respectively. The second AC lines 26C transmit AC signals, are arranged in a dendritic wiring manner, and are electrically connected with one third pad 23C connected with AC signals in each group of third pads 23 and one fourth pad 24C connected with AC signals in the fourth pad 24, so that each electrode unit 10 assembled with the corresponding female socket 25 of the third pad 23 is in an equipotential state, and the AC signal stability of the electrode patch 100 is ensured. One third pad 23C of each set of third pads 23, to which an AC signal is connected, is connected to the second AC line 26C in parallel, i.e., AC signal on-off of each electrode unit 10 assembled with the female socket 25 corresponding to the corresponding third pad 23 does not affect each other. Even if the electrode unit 10 is damaged during the use process, the other electrode units 10 are not influenced to continuously apply an alternating electric field to the tumor site of the patient for tumor electric field treatment. The second ground line 26A transmits a ground signal, is arranged in a dendritic wiring manner, and is electrically connected with one third pad 23A connected with the ground signal in each group of third pads 23 and one fourth pad 24A connected with the ground signal in the fourth pad 24. One third pad 23A of each set of third pads 23, to which a ground signal is connected, is connected to the second ground line 26A in parallel, i.e., the ground signal on-off of each electrode unit 10 assembled with the female socket 25 corresponding to the corresponding third pad 23 does not affect each other. The plurality of second signal lines 26B respectively transmit corresponding temperature signals and are electrically connected to one third pad 23B of the corresponding group of third pads 23, and a corresponding fourth pad 24B of the group of fourth pads 24, to which the temperature signals are connected, in a one-to-one correspondence. By means of the connection relationship between the third bonding pads 23, the fourth bonding pads 24 and the multiple second conductive traces 26, at least one group of the third bonding pads 23 are connected in parallel, so as to realize that at least one electrode unit 10 is connected to the adapter board 20 in parallel, and the connection and disconnection of the AC signal, the ground signal and the temperature signal of each electrode unit 10 are not affected.
That is, the plurality of third pads 23C are connected to the second AC line 26C in parallel. The plurality of third pads 23A are also connected in parallel to the second ground line 26A. The plurality of third pads 23B are connected to respective corresponding one of the signal lines 26B, and are connected to their respective fourth pads 24B through respective corresponding one of the signal lines 26B. Each female seat 25 is welded with the third bonding pad 23 of the corresponding group and is arranged on the adapter plate 20 in parallel, each electrode unit 10 can be connected to the adapter plate 20 in parallel after each electrode unit 10 is plugged onto the corresponding female seat 25 through the corresponding male seat 15, and therefore signal on-off between each electrode unit 10 and the adapter plate 20 is not affected, and even if one electrode unit 10 is damaged or the electrical connection between the electrode unit 10 and the adapter plate 20 is disconnected, the electrical connection and signal transmission between the other electrode units 10 and the adapter plate 20 are not affected.
The plurality of third bonding pads 23A for transmitting the grounding signal and one fourth bonding pad 24A for transmitting the grounding signal are respectively arranged at two opposite ends of one path of second grounding wire 26A, and the corresponding electrical connection between the third bonding pads 23A and the fourth bonding pads 24A is realized through the path of second grounding wire 26A, and the plurality of third bonding pads 23A are arranged at one end of the second grounding wire 26A in parallel connection, so that the grounding signal transmission of each electrode unit 10 is independent and does not affect each other after the plurality of electrode units 10 are inserted into the corresponding mother seat 25 of the adapter plate 20. One end of each second signal line 26B for transmitting temperature signals is connected with a third bonding pad 23B for transmitting temperature signals, and the other end is connected with a fourth bonding pad 24B for transmitting temperature signals and corresponding to the third bonding pad 23B so as to respectively transmit temperature signals collected by the temperature sensors 14 of the electrode units 10, so that the temperature signal transmission between the electrode units 10 can be independent and not affected after the electrode units 10 are plugged onto the adapter plate 20.
The third pads 23C for transmitting AC signals and the fourth pad 24C for transmitting AC signals are respectively disposed at opposite ends of a path of second AC line 26C, and electrically connected to the fourth pad 24C through the path of second AC line 26C, and the third pads 23C are disposed at one end of the second AC line 26C in parallel connection. The second AC lines 26C for transmitting AC signals are dendritic wires, one end of each second AC line is electrically connected to one third pad 23C of each third pad 23, and the other end of each second AC line is electrically connected to one fourth pad 24C of the fourth pads 24, so that the AC signal transmission of each electrode unit 10 can be independent and not affected after each electrode unit 10 is plugged into the corresponding female socket 25 of the interposer 20 through the corresponding male socket 15.
In the present embodiment, the number of fourth pads 24 is greater than the number of second conductive traces 26, which includes fourth pads 24A, 24B, 24C electrically connected to the corresponding second conductive traces 26, all being conductive pads. The fourth bonding pad 24 further includes a dummy bonding pad 24D disposed in a disconnected state from the second conductive trace 26, so as to enhance the bonding firmness between the flexible interposer 20 and the conductive leads 30.
In this embodiment, multiple second conductive traces 26 embedded in the interposer 20 are separated into two wiring layers, so as to avoid mutual interference between the second conductive traces 26. In this embodiment, the second AC lines 26C are distributed in one layer, and the second ground lines 26A and the second signal lines 26B are distributed in two wiring layers so as to avoid the second AC lines 26C. In other embodiments, the multiple second conductive traces 26 embedded in the interposer 20 are separated into three or more wiring layers, so as to improve flexibility of wiring the multiple second conductive traces 26.
As shown in fig. 4, 5A and 5B, in the present embodiment, the interposer 20 has a plurality of female sockets 25 respectively soldered with the corresponding sets of third pads 23. The plurality of female seats 25 are welded on the body 28 at intervals. The body 28 of the adapter plate 20 also has a trunk 21 and at least one limb 22. The wire connection portion 27 is located at one end of the trunk 21 of the body 28. The second conductive trace 26 of the interposer 20 is embedded in the trunk 21 and the branch 22 of the body 28. The plurality of female seats 25 are respectively welded on one trunk 21 and at least one branch 22 at intervals, so that the plurality of electrode units 10 are assembled on the adapter plate 20 at intervals through the plug-in cooperation of the female seats 25 and the male seats 15 of the electrode units 10, and meanwhile, the plurality of electrode units 10 are electrically connected with the adapter plate 20.
In this embodiment, the trunk 21 of the body 28 of the adapter plate 20 is provided with at least one through hole 211. The hollow hole 211 of the body 28 of the adapter plate 20 can allow the ceramic transduction piece 12 of the corresponding electrode unit 10 to pass through, so that the ceramic transduction piece 12 of the corresponding electrode unit 10 can be exposed to one side of the adapter plate 20 far away from the mother seat 25, and further the ceramic transduction piece 12 of the corresponding electrode unit 10 can pass through the adapter plate 20 to be configured on the skin surface of a human body.
In this embodiment, the adapter board 20 has 1 trunk 21 and 4 branches 22 extending from the trunk 21 toward two sides, and two sides of the trunk 21 are respectively provided with 2 branches 22. The branches 22 on different sides of the trunk 21 are aligned in pairs. The interval 221 which can allow the ceramic transduction piece 12 of the corresponding electrode unit 10 to pass through is arranged between the two adjacent limbs 22 positioned on the same side of the trunk 21, so that the ceramic transduction piece 12 of the corresponding electrode unit 10 can be exposed to the side of the adapter plate 20 far away from the mother seat 25, and the ceramic transduction piece 12 of the corresponding electrode unit 10 can be arranged on the skin surface of a human body through the adapter plate 20.
In this embodiment, 13 female sockets 25 are disposed on the adapter board 20, and the 13 female sockets 25 are respectively disposed on 1 trunk 21 and 4 branches 22 of the body 28. The trunk 21 is provided with 3 female seats, two limbs 22 close to the wiring part 27 are respectively provided with 2 female seats, and the other two limbs 22 are respectively provided with 3 female seats. Two hollow holes 211 are formed in the trunk 21 in a penetrating manner so as to accommodate the ceramic transduction plates of the corresponding 1 electrode unit 10 respectively. The 3 female seats 25 on the main body 21, the two hollow holes 211 on the main body 21 and the wiring portion 27 are all axisymmetrically arranged, and the symmetry axes of the three are in line coincidence. As shown in fig. 4, the 3 female seats 25 on the trunk 21 are aligned with two hollow holes 211 on the trunk 21 in a longitudinal direction. 2 of the 3 female seats 25 on the trunk 21 are arranged on the same side of one hollow hole 211 far away from the wiring part 27, and the other is arranged at a position between the two hollow holes 211 of the trunk 21.
The 2 female sockets 25 provided on the limbs 22 near the wire connection portion 27 are disposed on the corresponding limbs 22 in a substantially "L" shape. The 3 female seats 25 arranged on the branch 22 far from the wiring part 27 are approximately n-shaped and are arranged on the corresponding branch 22, and the opening of the n-shaped formed by the 3 female seats 25 faces the trunk 21. The plurality of female seats 25 provided on the limbs 22 are symmetrically arranged along the longitudinal symmetry axis of the trunk 21. 2 of the 5 female seats 25 on the two limbs 22 on the same side of the trunk 21 are respectively arranged at the end parts of the corresponding limbs 22 in a longitudinal alignment manner, and the remaining 3 are respectively arranged at the positions of the corresponding limbs 22 close to the trunk 21 in a longitudinal alignment manner. The 3 female seats 25 provided on the trunk 21 are arranged in longitudinal alignment. The 4 female seats 25 on the branches 22 located on opposite sides of the trunk 21 and both close to the connection portion 27 are arranged in a transverse alignment manner, specifically, the two female seats 25 respectively located on the ends of the two branches 22 close to the connection portion 27 are arranged in a transverse alignment manner, and the two female seats 25 respectively located on the two branches 22 close to the connection portion 27 and close to the trunk 21 are also arranged in a transverse alignment manner. Two female seats 25 which are arranged on two limbs 22 far from the wiring part 27 and are positioned at the end parts of the corresponding limbs 22 are arranged in a transverse alignment mode, 2 of 4 female seats 25 which are arranged on two limbs 22 far from the wiring part 27 and are positioned at the position, close to the trunk 21, of the corresponding limbs 22 are arranged in a transverse alignment mode, and the other 2 female seats are also arranged in a transverse alignment mode.
In this embodiment, the female sockets 25 located on the limbs 22 are uniformly distributed on the edges of the corresponding limbs 22, and the female sockets 25 located on the trunk 21 and the corresponding female sockets 25 located on the limbs 22 are respectively arranged in a transverse alignment manner, so that the second conductive traces 26 of the interposer 20 are arranged in a wiring manner, and each female socket 25 is arranged on the interposer in parallel through the second conductive traces 26. As shown in fig. 4 and 6B, the electrode units 10 detachably connected to the female sockets 25 located at the ends of the respective limbs 22 are horizontally assembled to the adapter plate 20, and the electrode units 10 detachably assembled to the female sockets 25 located outside the ends of the respective limbs 22 are longitudinally assembled to the adapter plate 20. In other embodiments, since the electrode units 10 are connected to the adapter plate 20 in parallel, the AC signal, the ground signal and the temperature signal of each electrode unit 10 are not affected by each other, and the number of the electrode units 10 detached from the adapter plate 20 is less than the number of the female sockets 25 on the adapter plate 20.
Referring to fig. 4, 5A, 5B and 8A, one end of the wire 30 is electrically connected to the connection portion 27 of the interposer 20, and the other end is provided with a plug 32. Preferably, the lead 30 is a lightning Mo Mu head sheathed wire. The wire 30 has a plurality of wire cores (not shown), each wire core (not shown) being soldered to a corresponding fourth pad 24 on both side surfaces of the wire connection portion 27, respectively. In the present embodiment, the number of electrode units 10 of the electrode patch 100 is 13, and the number of cores (not shown) of the wires 30 is 16. Accordingly, the wire 30 has a core (not shown) soldered to the fourth pads 24A, 24B, 24C and a core (not shown) soldered to the dummy pad 24D. The periphery of the welding position of the lead 30 and the wiring part 27 is also covered with a circle of heat-shrinkable sleeve 31 for sealing and insulating the welding position of the adapter plate 20 and the lead 30, so that the welding position of the adapter plate 20 and the lead 30 is prevented from being broken, and meanwhile, the waterproof and dustproof welding device can be used for preventing dust and water.
The wire 30 further includes shielding grid lines (not shown) wrapped around the plurality of wire cores (not shown). The fourth bonding pad 24 further includes a fourth bonding pad 24E at an end of the connection portion 27, which is soldered to a shielding grid line (not shown) of the wire 30 to shield the wire 30 from external signals interfering with signals transmitted from a plurality of cores (not shown) of the wire 30. The fourth pad 24E for shielding and the fourth pad 24A for transmitting a ground signal are connected to the second ground line 26A of the second conductive trace 26.
As shown in fig. 8A and 8B, the plug 32 of the lead 30 may be plugged with a patch cord 33, and the electrical connection between the plug and the electric field generator 200 may be achieved by plugging the patch cord 33 into the electric field generator 200, or the plug may be plugged with a patch cord 33 into the adapter 300, and then the plug and the electric field generator 200 may be plugged into the adapter 300 to achieve the electrical connection between the plug and the electric field generator 200. The patch cord 33 is detachably connected with the lead 30, so that the distance between the lead 30 and the electric field generator 200 or the adapter 300 can be increased or shortened as required, and only the lead 30 welded with the patch panel 20 can be scrapped when the electrode patch 100 is scrapped and needs to be replaced, without scrapping the patch cord 33, the cost can be reduced, and unnecessary waste can be avoided. The number of cores (not shown) of the patch cord 33 is identical to the number of cores (not shown) of the wire 30, and corresponds one by one. The patch cord 33 is a Rameret double-male-head sheath cord.
The backing 40 is provided in a sheet form and has at least one through hole 41 corresponding to the electrode unit 10 and provided therethrough. The through holes 41 of the backing 40 allow the corresponding portions of the electrode unit 10 to be exposed on a side surface thereof remote from the adapter plate 20, which is advantageous for dissipating heat generated by the electrode patch 100 during tumor electric field therapy. In this embodiment, the support plate 13 of the electrode unit 10 passes through the through hole 41 of the backing 40 and exposes a side surface of the backing 40 remote from the interposer 20. The through holes 41 of the backing 40 are slightly larger in size than the support plate 13.
The support 50 is provided in the form of a sheet having a plurality of perforations 51 provided therethrough. The plurality of through holes 51 of the support 50 include a plurality of first through holes 51A distributed corresponding to the respective electrode units 10 and two second through holes 51B arranged in a long bar shape and located between the plurality of first through holes 51A. Each first through hole 51A accommodates the ceramic transduction sheet 12 of the corresponding electrode unit 10. The surface of the support member 50 near the patient's body surface is flush with the surface of the ceramic transducer sheet 12 near the patient's body surface, so that the adhesive member 60 can be smoothly covered on the support member 50 and the ceramic transducer sheet 12, and the application comfort of the electrode patch 100 is improved. The two second through holes 51B correspond to the positions where the trunk 21 of the adapter plate 20 extends laterally to form the branches 22, so that part of heat of the electrode patch 100 can be transferred from the adapter plate 20 to the external environment through the backing 40 to achieve the purpose of heat dissipation. Both the second through holes 51B are long holes. The first through holes 51A are each slightly larger in size than one end of the electrode unit 10 to which the ceramic transducer sheet 12 is welded. Preferably, the support 50 is foam.
The adhesive member 60 is provided with a plurality of strips. Each adhesive member 60 is generally in the form of a strip having a double-sided adhesive surface that engages the corresponding portion of the support member 50 and ceramic transducer sheet 12 on one side and engages the patient's body surface on the other side. Preferably, the adhesive member 60 is an electrically conductive hydrogel. Each adhesive member 60 covers at least one ceramic transducer sheet 12 of an electrode unit 10. In this embodiment, the adhesive member 60 is provided with 5 pieces of ceramic transducer sheet 12 each covering 2 or 3 electrode units 10. The 3 adhesive pieces 60 are arranged transversely in parallel and cover the ceramic transduction plates 12 of the 3 electrode units 10; there are 2 adhesive members 60 arranged in parallel in the longitudinal direction and each covering 2 ceramic transduction plates 12 of the electrode unit 10. The 2 strips of adhesive means 60 arranged longitudinally in parallel are distributed on both sides of the 3 strips of adhesive means 60 arranged transversely in parallel.
The electrode patch 100 may further include at least one release paper 70. The release paper 70 is positioned on the side of the adhesive element 60 facing away from the backing 40 and covers the adhesive element 60 and the corresponding portion of the backing 40 to protect the adhesive element 60 and the backing 40 from contamination of the adhesive element 60 and the backing 40. In this embodiment, the electrode patch 100 has two release papers 70. Two release papers 70 collectively cover the adhesive 60 and the backing 40.
The electrode patch 100 of the tumor electric field treatment system 1000 is formed by detachably connecting the plurality of electrode units 10 with the adapter plate 20, and the plurality of electrode units 10 are connected to the adapter plate 20 in parallel, so that the AC signals of the plurality of electrode units 10 are not affected by each other, even if the electrode units 10 are damaged in the use process, the other electrode units 10 are not affected, and the alternating electric field is continuously applied to the tumor part of a patient for tumor electric field treatment, the stability of the electric signals of the tumor electric field treatment is improved, and the treatment cost of the patient can be reduced to a certain extent.
The foregoing description of the preferred embodiments of the present application is not intended to be limiting, but rather is intended to cover any and all modifications, equivalents, alternatives, and improvements that fall within the spirit and principles of the present application.
Claims (10)
1. The electrode patch is used for tumor electric field treatment and is characterized by comprising a plurality of electrode units, an adapter plate and a back lining, wherein the adapter plate is formed by a flexible circuit board, the electrode units and the adapter plate are adhered to the back lining, each electrode unit comprises a flexible plate matrix, a transduction piece and a male seat, and the transduction piece and the male seat are respectively arranged at two opposite ends of one side surface of the flexible plate matrix, which is far away from the back lining, and are electrically connected with each other; the adapter plate is provided with a body and a plurality of female seats, the female seats are arranged on the body at intervals, and the body is provided with hollowed holes or intervals; the electrode unit is provided with a plurality of electrode units, one end of each electrode unit is provided with a male seat, one end of each electrode unit is clamped between the adapter plate and the backing, one end of each electrode unit is provided with a replaceable energy piece, the adapter plate is exposed out through the hollow hole or the interval, the male seats are inserted with the corresponding female seats so that the plurality of electrode units are detachably and electrically connected to the adapter plate, a second AC line for transmitting alternating electric signals is embedded in the adapter plate, and the plurality of energy pieces are connected to the second AC line in parallel through the electrical connection of the male seats and the female seats.
2. The electrode patch according to claim 1, wherein the body is provided with a trunk and a plurality of branches located on both sides of the trunk, the plurality of female seats are distributed on the trunk and the branches, and the interval is provided between two adjacent branches located on the same side of the trunk.
3. The electrode patch of claim 2, wherein the stem is provided with the hollowed-out hole.
4. The electrode patch of claim 1, wherein the electrode unit further comprises a temperature sensor disposed on the flexible board substrate, the transduction piece has a through hole for accommodating the temperature sensor, the temperature sensor has a grounding end and a signal end, the interposer is embedded with a second grounding wire and multiple parallel second signal wires, the grounding ends of the electrode units are connected in parallel to the second grounding wire through the electrical connection between the male base and the female base, and the signal ends of the electrode units are connected to the corresponding second signal wires through the electrical connection between the male base and the female base.
5. The electrode patch of claim 4, wherein the second AC line and the second ground line are each in a dendritic wiring arrangement.
6. The electrode patch according to claim 4, further comprising a wire, wherein the interposer is provided with a wiring portion connected to one end of the body, and a plurality of fourth bonding pads welded to the wire are provided on both side surfaces of the wiring portion, and the plurality of fourth bonding pads include a plurality of conductive bonding pads, and the conductive bonding pads are electrically connected to the corresponding second AC line, second ground line, or second signal line.
7. The electrode patch of claim 6, wherein at least one dummy pad is further included in the fourth plurality of pads, and none of the dummy pads is electrically connected to the second AC line, the second ground line, and the second signal line.
8. The electrode patch of claim 1, wherein the backing is sheet-like and has a plurality of through holes exposing a plurality of the electrode units.
9. The electrode patch of claim 1, further comprising a support member surrounding respective portions of the plurality of electrode units and adhered to the backing, and an adhesive member covering the support member and the plurality of electrode units, the support member being provided with first perforations for receiving the electrode units and second perforations between the plurality of first perforations.
10. A tumor electric field therapy system comprising an electric field generator and at least one pair of electrode patches according to any one of claims 1 to 9 electrically connected to the electric field generator.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311589199.1A CN117482385A (en) | 2022-12-26 | 2022-12-26 | Electrode patch and tumor electric field treatment system |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311589199.1A CN117482385A (en) | 2022-12-26 | 2022-12-26 | Electrode patch and tumor electric field treatment system |
| CN202211678884.7A CN115814263B (en) | 2022-12-26 | 2022-12-26 | Electrode patch and tumor electric field treatment system |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211678884.7A Division CN115814263B (en) | 2022-10-27 | 2022-12-26 | Electrode patch and tumor electric field treatment system |
Publications (1)
| Publication Number | Publication Date |
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| CN117482385A true CN117482385A (en) | 2024-02-02 |
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