CN114099954A - Electric field therapeutic apparatus and electrode patch thereof - Google Patents

Electric field therapeutic apparatus and electrode patch thereof Download PDF

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Publication number
CN114099954A
CN114099954A CN202111578531.5A CN202111578531A CN114099954A CN 114099954 A CN114099954 A CN 114099954A CN 202111578531 A CN202111578531 A CN 202111578531A CN 114099954 A CN114099954 A CN 114099954A
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electrode
electrode units
electrode patch
patch
adjacent
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CN202111578531.5A
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CN114099954B (en
Inventor
陈晟
孙虎
沈琪超
于晶
张军
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Jiangsu Hailai Xinchuang Medical Technology Co Ltd
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Jiangsu Hailai Xinchuang Medical Technology Co Ltd
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Priority to CN202111578531.5A priority Critical patent/CN114099954B/en
Publication of CN114099954A publication Critical patent/CN114099954A/en
Priority to PCT/CN2022/134677 priority patent/WO2023051845A1/en
Priority to PCT/CN2022/134717 priority patent/WO2023051846A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002—Cancer treatment, e.g. tumour
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K1/00—Printed circuits
    • H05K1/02—Details
    • H05K1/0277—Bendability or stretchability details
    • H05K1/028—Bending or folding regions of flexible printed circuits

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The invention provides an electric field therapeutic apparatus and an electrode patch thereof, which are used for electric field therapy of tumors, wherein the electrode patch comprises a plurality of electrode units for applying an alternating electric field to a tumor part of a patient, a plurality of connecting parts for connecting two adjacent electrode units and a wiring part connected with the connecting parts, the plurality of electrode units are arranged in at least three rows and four columns, each electrode unit is connected with at least two connecting parts, the plurality of electrode units are arranged at intervals to form a plurality of open spaces positioned between the electrode units, and the wiring part is arranged in a manner of penetrating through one open space. The electric field therapeutic apparatus and the electrode patch thereof have the open space positioned among the plurality of electrode units, so that heat accumulated on the surface of the skin corresponding to the electrode patch applied to a patient and water vapor generated by sweating can be discharged to the external air through the open space in the electric field treatment process of tumors, and skin discomfort symptoms such as erythema, pruritus, follicular inflammation, pain, pimple and the like can be avoided.

Description

Electric field therapeutic apparatus and electrode patch thereof
Technical Field
The invention relates to an electric field therapeutic apparatus and an electrode patch thereof, belonging to the technical field of medical instruments.
Background
At present, the treatment modes of tumors mainly comprise operations, radiotherapy, chemotherapy and the like, but the methods have corresponding defects, for example, radiotherapy and chemotherapy can generate side effects and kill normal cells. The electric field treatment of tumor is one of the current development fronts, and the tumor electric field treatment generates a tumor treatment method which interferes the mitosis process of tumor cells through a low-intensity, medium-high frequency and alternating electric field by a special electric field generator. Research shows that the electric field treatment has obvious effect in treating diseases such as glioblastoma, non-small cell lung cancer, malignant pleural mesothelioma and the like, and the electric field applied by the treatment method can influence the aggregation of tubulin, prevent spindle formation, inhibit mitosis process and induce cancer cell apoptosis.
The electric field therapeutic apparatus for treating tumor mainly comprises an electric field generator and an electrode patch electrically connected with the electric field generator. The electrode patch comprises an electrode array capable of transmitting an alternating electric field, wherein the electrode array comprises a flexible circuit board, an insulation board fixedly arranged on one side of the flexible circuit board, which is far away from the skin, and a dielectric element welded on one side of the flexible circuit board, which is facing the skin. In order to achieve better therapeutic effects, it is necessary to dispose the electrode patch on the skin surface corresponding to the tumor site of the patient for a long time to perform the alternating electric field tumor therapy. When an alternating electric field is applied to a tumor part of a patient through an electrode patch for a long time to treat tumors, heat is collected on the surface of the skin, and sweat is generated to generate water vapor. If the water vapor can not be discharged in time, sweat glands and hair follicles on the outer part of the skin can be blocked, and skin discomfort symptoms such as skin erythema, pruritus, hair follicle inflammation, pain, pimple and the like can be caused.
Therefore, there is a need to provide an improved electrode patch and an electric field treatment apparatus, which overcome the above-mentioned problems of the electrode patch and the electric field treatment apparatus.
Disclosure of Invention
The invention provides an electrode patch and an electric field therapeutic apparatus, which can dissipate heat and drain steam and avoid skin discomfort.
The electrode patch is realized by the following technical scheme: the utility model provides an electrode patch for tumour electric field treatment, its includes a plurality of electrode units, a plurality of connecting portion of connecting two adjacent electrode units and a wiring portion of being connected with connecting portion that apply alternating electric field to patient's tumour position, a plurality of electrode units are the triplex row four rows at least and arrange, every electrode unit all is connected with two connecting portions at least, a plurality of electrode units are the form setting of interval in order to form a plurality of open spaces that are located between the electrode unit, wiring portion is and passes an open space form setting.
Further, the distance between two adjacent electrode units in the same row is the same.
Further, the distance between two adjacent electrode units in the same row is 8mm-22 mm.
Further, the distance between two adjacent electrode units in the same column is the same.
Further, the distance between two adjacent electrode units in the same column is 6.5mm-25 mm.
Furthermore, the distances between two adjacent electrode units which are positioned in adjacent rows and adjacent columns and arranged diagonally are the same.
Furthermore, the distance between two adjacent electrode units which are positioned in adjacent rows and adjacent columns and arranged diagonally is 19mm-33.3 mm.
Further, the electrode unit is in a circular sheet-shaped structure, and the diameter of the electrode unit is approximately 21mm-22 mm.
Further, the plurality of electrode units are distributed at intervals in an area of 242mm × 166mm at most.
Further, the plurality of electrode units are distributed at intervals in an area of 166mm × 103.5mm at the minimum.
Further, the width of the connecting part is 4.5mm-6 mm.
Further, the width of the connecting part is 4.5 mm.
Furthermore, at least two adjacent electrode units in the same row or the same column in the plurality of electrode units are arranged in a disconnected manner, and an interval C is formed between the two adjacent electrode units arranged in the disconnected manner.
Further, the wire connection portion passes through the space C.
Furthermore, the wire connecting part is laterally extended towards the direction of the interval C from the connecting part.
Further, the wire connecting portion is substantially in a line shape.
Further, the wiring portion is bridged between two connecting portions respectively connected to the two electrode units arranged at intervals.
Further, the wire connecting portion is arranged in a T shape.
Further, the wire connecting portion includes a bridge section bridged between the two connecting portions and a wire connecting section extended from the bridge section toward the space C.
Further, the bridging section of wiring portion all is perpendicular form setting rather than two connecting portion of being connected, the wiring section and the bridging section of wiring portion are perpendicular form setting.
Furthermore, the width of the bridging section of the wiring part is 4.5mm-6mm, and the width of the wiring section of the wiring part is 4mm-8 mm.
Furthermore, the number of the electrode units is 20, and the electrode units are distributed in an array area surrounded by four rows and six columns.
Furthermore, the 20 electrode units are distributed in an array area with four rows and six columns in a mode that the first row and the last row are respectively provided with four electrode units, and the middle two rows are respectively provided with six electrode units.
Further, the area of the largest open space of the plurality of open spaces is approximately 4428mm2. Further, the area of the smallest open space among the plurality of open spaces is 452mm2。
Furthermore, the wire connecting structure also comprises a wire which is welded with the wire connecting part.
Further, the wire-passing device comprises a backing supporting the plurality of electrode units, and the backing is provided with wire-passing holes for the wires to pass through.
The electric field therapeutic apparatus is realized by the following technical scheme: an electric field therapeutic apparatus comprises an electric field generator and the electrode patch electrically connected with the electric field generator.
The electrode patch provided by the invention is provided with the open space among the plurality of electrode units, so that heat accumulated on the surface of the skin corresponding to the electrode plate applied to a patient and water vapor generated by sweating can be discharged to the external air through the open space in the tumor electric field treatment process, and skin discomfort symptoms such as erythema, pruritus, follicular inflammation, pain, pimple and the like can be avoided.
Drawings
FIG. 1 is a perspective view of an electrode patch of an electric field treatment apparatus according to an embodiment of the present invention.
Fig. 2 is an exploded perspective view of the electrode patch of fig. 1.
Fig. 3 is an exploded perspective view of the electrode array and the lead of fig. 2.
Fig. 4 is a schematic plan view of a dielectric element of the electrode array of fig. 3.
Description of reference numerals:
the electrode patch 100, the electrode array 1, the electrode unit 10, the flexible circuit board 11, the main body portion 111, the connection portion 112, the wire connection portion 113, the bridge section 1130, the wire connection section 1131, the gold finger 1132, the conductive pad 114, the conductive core 1140, the insulating plate 12, the dielectric element 13, the through hole 131, the metal layer 132, the temperature sensor 14, the open space 15, the backing 2, the wire through hole 21, the support 3, the support unit 30, the through hole 31, the lead wire 4, the heat shrinkable sleeve 41, the plug 42, the adhesive 5, the insulating substrate B, and the space C.
Detailed Description
Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, like numbers in different drawings represent the same or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present invention. Rather, they are merely examples of devices, systems, apparatus, and methods consistent with certain aspects of the invention.
The therapeutic electric field apparatus (not shown) for treating tumor of the present invention comprises an electric field generator (not shown) and an electrode patch 100 connected to the electric field generator (not shown), wherein the electrode patch 100 is attached to the skin surface of a human body to apply a therapeutic electric field generated by the electric field generator (not shown) to the human body. The electrode patch 100 of the embodiment of the invention is applied to the trunk part of a human body for assisting in treating tumors of the corresponding part.
Referring to fig. 1 to 4, the electrode patch 100 includes a backing 2, an electrode array 1 adhered to the backing 2, a support 3 adhered to the backing 2, an adhesive member 5 covering a portion of the support 3 corresponding to the electrode array 1, and a lead wire 4 electrically connected to the electrode array 1. The electrode patch 100 is attached to the body surface of a patient corresponding to the tumor part through the backing 2, and an alternating electric field is applied to the tumor part of the patient through the electrode array 1 to interfere or prevent mitosis of tumor cells of the patient, so that the purpose of treating tumors is achieved.
The electrode array 1 is arranged in a grid shape and comprises a plurality of electrode units 10 arranged in an array, a plurality of connecting parts 112 for connecting two adjacent electrode units 10 and a wiring part 113 welded with the lead 4. The plurality of electrode units 10 are distributed at intervals on grid points of the electrode array 1. Each of the electrode units 10 is connected to at least two adjacent electrode units 10 by a connecting portion 112. Each of the electrode units 10 is connected to at least two connection portions 112. The plurality of electrode units 10 is at least ten and distributed in an array area with at least three rows and four columns. The plurality of adjacent electrode units 10 are arranged at intervals and form an open space 15 to allow the skin of the patient, which is covered by the electrode patch 100 and corresponds to the tumor region of the patient, to freely breathe after the electrode patch 100 is disposed on the body surface of the patient corresponding to the tumor region. The wiring portion 113 is located between the plurality of electrode units 10 and disposed in the open space 15 surrounded by the plurality of electrode units 10, so that the overall size of the electrode array 1 can be prevented from being too large, which leads to an increase in manufacturing cost.
The electrode unit 10 is of a generally circular sheet-like configuration. The diameter of the electrode unit 10 is approximately 21mm-22 mm. The spacing between two adjacent electrode units 10 arranged in a row is the same. The spacing between two adjacent electrode units 10 in the same row is at least 8 mm. The distance between two adjacent electrode units 10 arranged in a row is the same. The spacing between two adjacent electrode units 10 in the same column is at least 6.5 mm. The distances between the two adjacent electrode units 10 which are located in adjacent rows and adjacent columns and arranged diagonally are the same. The spacing between two adjacent electrode units 10 located in adjacent rows and adjacent columns and arranged diagonally is at least about 19 mm.
Preferably, in the present embodiment, the number of the electrode units 10 is 20, and the plurality of electrode units 10 are distributed in an array of four rows and six columns at intervals. From the line arrangement perspective, each line of the first line and the last line is provided with 4 electrode units 10, and each line of the middle two lines is provided with 6 electrode units 10; from the column arrangement perspective, the first column and the sixth column are respectively provided with 2 electrode units 10, and the middle four columns are respectively provided with 4 electrode units 10. Specifically, the first row of 4 electrode units 10 is located in each of the second to fifth columns, the middle two rows of 6 electrode units 10 are located in each of the first to sixth columns, and the last row of 4 electrode units 10 is located in each of the second to fifth columns. The plurality of electrode units 10 of the electrode array 1 are arranged in a line-direction axisymmetric manner and a column-direction axisymmetric manner. The electrode array 1 is generally in the form of an octagonal plate with a minimum length of 166mm and a minimum width of 103.5 mm. That is, all the electrode units 10 of the electrode array 1 are distributed at intervals in an area of at least 166mm × 103.5 mm. The electrode patch with the size can be suitable for children with small waistlines.
In order to prevent the electrode patch 100 from being applied to the body surface of the tumor region of the patient and then the electrode array 1 from overlapping to affect the treatment effect, the distance between two adjacent electrode units 10 in the same row is at most 22mm, the distance between two adjacent electrode units 10 in the same column is at most 25mm, and the distance between two adjacent electrode units 10 in adjacent rows and adjacent columns and arranged diagonally is at least about 33.3 mm. The diameter of the combined electrode unit 10 is 22mm at most, and the length of the electrode array 1 is 242mm at most and the width is 166mm at most. That is, all the electrode units 10 of the electrode array 1 are distributed at intervals in an area of 242mm × 166mm at maximum. The maximum size of the electrode array 1 may be suitable for most adult patients. If the waist of the patient is larger, the two pairs of electrode patches 100 can be transversely attached to the waist of the patient for a circle. If the waist circumference of the patient is small, the two pairs of electrode patches 100 can be longitudinally applied to the waist circumference of the patient. If the waist of the patient is proper, one pair of electrode patches 100 may be transversely applied to the waist of the patient, the other pair of electrode patches 100 may be longitudinally applied to the waist of the patient, and the two pairs of electrode patches 100 are applied around the waist of the patient.
The connecting portion 112 is located between two adjacent electrode units 10. Each of the electrode units 10 is connected to at least three adjacent electrode units 10 by a connecting portion 112. Each of the electrode units 10 is connected to at least three connecting portions 112. At least one adjacent two electrode units 10 arranged in a row or a column among the plurality of electrode units 10 are arranged in a broken state, and a space C is formed between the adjacent two electrode units 10 arranged in the broken state and through which the wire connecting portion 113 passes. In the present embodiment, two electrode units 10 located in the second row, the third column, and the fourth column are provided in a broken state, and two electrode units 10 located in the third row, the third column, and the fourth column are also provided in a broken state.
The connecting portions 112 are located between two adjacent electrode units 10 in the same row, between two adjacent electrode units 10 in the same column, and between two adjacent electrode units 10 in adjacent rows and adjacent columns and arranged diagonally. The connecting parts 112 connecting two adjacent electrode units 10 in the same row have the same length, and the connecting parts 112 connecting two adjacent electrode units 10 in the same column have the same length. The plurality of adjacent two electrode units 10 connected in adjacent rows and adjacent columns and arranged diagonally have the same length. The length dimension of the connecting portion 112 is substantially the same as the interval between the two electrode units 10 connected thereto. The length of the connecting parts 112 connecting two adjacent electrode units 10 in the same row is about 8mm-22mm, and the length of the connecting parts 112 connecting two adjacent electrode units 10 in the same column is about 6.5mm-25 mm. The length of the two adjacent electrode units 10 which are connected and positioned in adjacent rows and adjacent columns and arranged in a diagonal shape is about 19mm-33.3 mm. The width of all the connecting parts 112 between two adjacent electrode units 10 is 4.5mm-6 mm. Preferably, the width of the connecting portion 112 is 4.5 mm.
In this embodiment, the wire connecting portion 113 is located between two rows of electrode units 10 in the middle. That is, the wire portion 113 is located between the electrode units 10 of the third and fourth columns. The wire connecting portion 113 has a T-shaped configuration, and the wire connecting portion 113 is bridged between two connecting portions 112 connected to two adjacent electrode units 10 arranged in a disconnected state, respectively. The wire connecting portions 113 are arranged in an axisymmetrical manner. One of the two connecting portions 112 connected to the wire connecting portion 113 is located between the middle two electrode units 10 of the third column, and the other is located between the middle two electrode units 10 of the fourth column. The wire connecting portion 113 includes a bridge section 1130 bridged between two opposite connecting portions 112 and a wire connecting section 1131 connected to the lead wire 4. The wiring section 1131 and the bridge section 1130 are arranged perpendicularly. The bridge section 1130 of the wiring portion 113 and the two connecting portions 112 connected thereto are both arranged vertically, and the wiring section 1131 of the wiring portion 113 and the two connecting portions 112 connected to the wiring portion 113 are both arranged in parallel. The bridging section 1130 of the wire connecting portion 113 is bridged between two adjacent connecting portions 112 located in the middle, and the wire connecting section 1131 of the wire connecting portion 113 is laterally extended from the middle of the bridging section 1130.
The width of the wire connecting section 1131 of the wire connecting portion 113 is at least 4mm, and the distance between the wire connecting section 1131 of the wire connecting portion 113 and the adjacent electrode unit 10 is at least 2 mm. Preferably, the width of the wire section 1131 of the wire connecting portion 113 is 4mm to 8 mm. The width of the bridging section 1130 of the wire connecting portion 113 is 4.5mm-6mm, and the distance between the bridging section 1130 of the wire connecting portion 113 and the adjacent electrode unit 10 is at least 1 mm. Preferably, the bridge segment 1130 of the wire connecting portion 113 has the same width as the connecting portion 112. Alternatively, the wire connecting portion 113 is disposed substantially in a line shape, and is laterally extended in the direction of the interval C from the connecting portion 112 between two adjacent electrode units 10.
Preferably, in the present embodiment, referring to fig. 2 and 3, the electrode sheetThe diameter of the element 10 is 21 mm. The spacing between two adjacent electrode units 10 arranged in a row is 15 mm. The distance between two adjacent electrode units 10 arranged in a row is 23 mm. The length of the connecting parts 112 connecting the two adjacent electrode units 10 in the same row is 15mm, the length of the connecting parts 112 connecting the two adjacent electrode units 10 in the same column is 23mm, and the length of the two adjacent electrode units 10 connecting the two adjacent electrode units 10 in the adjacent rows and the adjacent columns and arranged diagonally is about 27.5 mm. The width of the connecting portion 112 is 4.5 mm. The width of the bridge section 1130 of the wire connecting portion 113 is 4.5mm, the width of the wire connecting section 1131 of the wire connecting portion 113 is 8mm, and the length of the wire connecting section 1131 of the wire connecting portion 113 is 42 mm. The electrode array 1 has a length of 201mm and a width of 153 mm. The electrode array 1 is formed such that the areas of the open spaces 15 between the plurality of electrode units 10 are not completely the same. In the present embodiment, of all the open spaces 15, the open space 15, which is located between the eight electrode units 10 in the two columns in the middle and through which the wire bonding portion 113 passes, has the largest area, which is about 4428mm2. The open spaces 15 at the four corners of the electrode array 1 have the smallest area. The open space 15 at the corner of the electrode array 1 is formed by the common surrounding of three electrode units 10 which are adjacent in pairs and in the same row, adjacent in pairs and in the same column, form adjacent rows and adjacent columns in pairs and are arranged in a diagonal shape, and the area of the open space is about 452mm2. The area of other open spaces 15 formed by the surrounding of four electrode units 10 in adjacent rows and adjacent columns is about 1066mm2。
One end of the wiring portion 113 of the electrode array 1, which is far away from the connecting portion 112 connected thereto, is electrically connected to the lead wire 4. The lead 4 is electrically connected to one end of the wiring section 1131 of the wiring portion 113 away from the bridge section 1130. In the present embodiment, a row of gold fingers 1132 welded to the lead wire 4 is provided in a staggered manner on both side surfaces of one end of the wire connecting section 1131 of the wire connecting portion 113 away from the bridge section 1130 connected thereto. One end of the lead wire 4 is electrically connected to the gold finger 1132 of the wire connecting portion 113; the other end is electrically connected to an electric field generator (not shown) through a plug 42 disposed at the end, so as to provide the electrode patch 100 with an alternating current signal for tumor therapy during tumor electric field therapy. The periphery of the welding position of the lead wire 4 and the gold finger 1132 of the wire connecting portion 113 is covered with a heat shrinkable sleeve 41. The heat-shrinkable sleeve 41 performs insulation protection on the connection part of the lead 4 and the wiring part 113 of the electrode array 1, provides support, prevents the connection part of the lead 4 and the wiring part 113 of the electrode array 1 from being broken, and is dustproof and waterproof.
The electrode unit 10 includes a main body 111 provided at a distal end of a connecting portion 112, an insulating plate 12 provided on a side of the main body 111 remote from the skin of the human body, a dielectric element 13 provided on a side of the main body 111 facing the skin of the human body, and a temperature sensor 14 selectively provided on the main body 111 and located on the same side as the dielectric element 13. The main body 111, the insulating plate 12, and the dielectric element 13 are all of a circular sheet-like structure. The insulating plate 12, the main body 111, and the dielectric element 13 are disposed in one-to-one correspondence in the thickness direction, and the centers of the three are located on the same straight line.
A conductive plate 114 is disposed on a surface of the main body 111 facing the dielectric element 13. The conductive pad 114 of the main body 111 can be completely covered by the dielectric element 13, so that the conductive pad 114 and the dielectric element 13 are soldered by a solder (not shown). The conductive pad 114 of the main body 111 includes a plurality of conductive cores 1140 disposed in a central symmetry, which can effectively prevent the dielectric element 13 from being displaced due to stacking of solder (not shown) during the soldering process. The conductive pad 114 of the main body 111 is centered on the centerline of the main body 111. The top surfaces of the conductive cores 1140 of the conductive pad 114 are located on the same plane, so as to avoid the occurrence of solder joint cold joint between the conductive cores 1140 and the dielectric element 13. The center of the conductive pad 114 is also located on the centerline of the dielectric element 13.
In this embodiment, the conductive pad 114 of the same main body 111 includes 4 conductive cores 1140 arranged at intervals and in a central symmetry. The conductive core 1140 adopts a multipoint interval arrangement mode, so that the consumption of copper foil for manufacturing the conductive core 1140 can be reduced, and the material cost is reduced; meanwhile, the amount of solder (not shown) used for welding the conductive core 1140 and the dielectric element 13 can be saved, thereby further reducing the material cost. All of the 4 conductive cores 1140 of the same conductive pad 114 are petal-shaped. Each conductive core 1140 includes inner arcs (not numbered) and outer arcs (not numbered) that are connected end to end. The inner arcs (not numbered) and the outer arcs (not numbered) of the conductive core 1140 are arranged in an axial symmetry. The inner arcs (not numbered) of the 4 conductive cores 1140 of the same conductive pad 114 are all recessed toward the center of the conductive pad 114. The outer arcs (not numbered) of the 4 conductive cores 1140 of the same conductive pad 114 all protrude away from the center of the conductive pad 114. The 4 conductive cores 1140 forming the conductive disc 114 are arranged in a central symmetry manner and in an axial symmetry manner, and each conductive core 1140 is also arranged in an axial symmetry manner, so that when the 4 conductive cores 1140 of the conductive disc 114 of the main body part 111 are welded with the dielectric element 13, the stress balance of each welding point between the conductive disc 114 and the dielectric element 13 is ensured, the integral welding balance of the dielectric element 13 is ensured, the welding quality is improved, and the situation that the welding part on the side with larger interval between the dielectric element 13 and the main body part 111 is weak in strength and easy to break due to the inclination of the dielectric element 13 caused by the unbalanced welding stress is avoided; while also avoiding an impact on the degree of fit of the electrode patch 100.
The insulating plate 12 is made of an insulating material. Preferably, the insulating plate 12 is an epoxy glass cloth laminate. The insulating plate 12 is adhered to the surface of the main body 111 away from the skin of the human body by a sealant (not shown), so that the strength of the main body 111 can be enhanced, a flat welding plane can be provided for the welding operation between the main body 111 and the dielectric element 13, and the product yield can be improved. Meanwhile, the insulating plate 12 can also isolate the moisture in the air on the side of the electrode patch 100 away from the skin from contacting the solder (not shown) between the main body 111 and the dielectric element 13, so as to prevent the moisture from eroding the solder (not shown) between the main body 111 and the dielectric element 13 and affecting the electrical connection between the main body 111 and the dielectric element 13.
The size of the insulating plate 12 is the same as that of the main body portion 111, so that when the insulating plate 12 is stuck to one side, far away from the human skin, of the main body portion 111 through a sealant (not shown), the sealant (not shown) climbs to one side, facing the human skin, of the main body portion 111 through a capillary effect, and the filling of the sealant (not shown) in a gap (not shown) formed by welding the dielectric element 13 and the main body portion 111 is affected, a cavity exists in the sealant (not shown), and further, the phenomenon that when the sealant (not shown) is cured at a high temperature, because the difference between the thermal expansion coefficients of water vapor in the cavity and the sealant (not shown) is large, the water vapor rapidly expands to cause bursting, popcorn is generated, and the product is damaged is avoided.
The dielectric element 13 is made of a high dielectric constant material, has a conductive characteristic of blocking conduction of direct current and allowing alternating current to pass through, and can ensure safety of a human body. Preferably, the dielectric element 13 is a dielectric ceramic sheet. The dielectric element 13 is in a ring-shaped configuration, and a through hole 131 is formed through the middle thereof for accommodating the temperature sensor 14. An annular metal layer 132 is attached to a surface of the dielectric element 13 facing the body 111. The metal layer 132 of the dielectric element 13 and the conductive core 1140 of the conductive pad 114 of the main body 111 are welded point to surface, so that high welding alignment precision is not required, and welding is more convenient. A gap (not shown) formed by welding the dielectric element 13 and the main body part 111 is filled with a sealant (not shown) to protect a soldering tin (not shown) between the dielectric element 13 and the main body part 111, so as to avoid the fracture of the welding position caused by the influence of an external force on the dielectric element 13, and further prevent an alternating electric field from being applied to a tumor part of a patient through the dielectric element 13; while also ensuring that the dielectric element 13 is secured to the body portion 111 by a sealant (not shown). The inner ring of the metal layer 132 of the dielectric element 13 is spaced from the edge of the through hole 131 of the dielectric element 13, so that it is possible to prevent a solder (not shown) provided between the metal layer 132 of the dielectric element 13 and the main body 111 from diffusing in the direction of the through hole 131 of the dielectric element 13 when melted by heat and causing a short circuit of the temperature sensor 14. The outer ring of the metal layer 132 of the dielectric element 13 is spaced from the outer edge of the dielectric element 13, so that solder (not shown) between the metal layer 132 of the dielectric element 13 and the main body 111 can be prevented from overflowing to the outside of the main body 111 when being melted by heat, and direct current which is not blocked by the dielectric element 13 can be prevented from passing through and acting on the body surface of the patient when the electrode patch 100 is attached to the body surface of the tumor region of the patient.
The outer diameter of the dielectric element 13 is slightly smaller than the diameter of the main body 111, and the sealant (not shown) fills the gap (not shown) along the edge of the main body 111 outside the dielectric element 13 by capillary phenomenon, so as to facilitate filling of the sealant (not shown) in the gap (not shown) formed by welding the dielectric element 13 and the main body 111. Preferably, the outer diameter of the dielectric element 13 is smaller than the diameter of the body 111 by 1 mm. When the through hole 131 of the dielectric element 13 is connected and a sealant (not shown) is filled in a gap (not shown) formed by welding the dielectric element 13 and the main body 111, air in the gap (not shown) can be discharged from the through hole 131 of the dielectric element 13, so that a void is prevented from being generated in the sealant (not shown) filled in the gap (not shown), and the product quality is improved.
The plurality of temperature sensors 14 are accommodated in the through holes 131 of the corresponding dielectric elements 13. In the present embodiment, the number of the temperature sensors 14 is eight, and the four temperature sensors are respectively located on the four electrode units 10 at the four corners of the electrode array 1 and the four electrode units 10 located on the second row, the second column, the third row, the second column, the second row, the fourth column, and the third row, the fourth column. The eight temperature sensors 14 are respectively provided at the centers of the main body portions 111 of the corresponding electrode units 10. The temperature sensor 14 is used for monitoring the temperature of the adhesive member 5 covering the side of the dielectric element 13 of the electrode array 1 facing the skin of the human body, and further detecting the temperature of the skin of the human body to which the adhesive member 5 is attached. When the temperature monitored by the temperature sensor 14 exceeds the upper limit of the human body safety temperature, an electric field generator (not shown) timely reduces or turns off the alternating current so as to avoid low-temperature scald of the human body. The temperature sensor 14 is welded to the body portion 111 and then sealed with a sealant (not shown) to securely fix the temperature sensor 14 while preventing moisture from corroding the temperature sensor 14 and causing the temperature sensor 14 to fail. The temperature sensor 14 has a signal terminal (not shown) and a ground terminal (not shown). In other embodiments, the specific number of temperature sensors 14 may be set as desired. The temperature sensor 14 is preferably a thermistor.
Referring to fig. 3, the main body portions 111 of the electrode units 10 arranged in four rows and six columns, the connecting portions 112 connecting two adjacent electrode units 10, and the wire connecting portions 113 connecting two adjacent connecting portions 112 together constitute the flexible circuit board 11 of the electrode array 1. From the perspective of forming the electrode unit 10, the insulating plate 12 is disposed on the side of the main body portion 111 of the flexible circuit board 11 facing away from the skin of the human body, the dielectric element 13 is disposed on the side of the main body portion 111 of the flexible circuit board 11 facing the skin of the human body, and the temperature sensor 14 is selectively disposed on the side of the main body portion 111 of the flexible circuit board 11 facing the skin of the human body. The main body portion 111 of the flexible circuit board 11 is arranged in conformity with the arrangement of the electrode unit 10.
The flexible circuit board 11 is composed of an insulating substrate B and a plurality of conductive traces (not shown) embedded in the insulating substrate B. The conductive trace (not shown) embedded in the insulating substrate B of the main body portion 111, the conductive trace (not shown) embedded in the insulating substrate B of the connecting portion 112, and the conductive trace (not shown) embedded in the insulating substrate B of the wire connecting portion 113 are electrically connected. The insulating substrate B of the connecting portion 112 is embedded with a conductive trace (not shown), and the remaining connecting portion 112 only includes the insulating substrate B to reinforce the strength of the flexible circuit board 11. The conductive core 1140 is exposed or protruded from the insulating substrate B of the main body 111. The insulating substrate B of the flexible circuit board 11 can isolate moisture in the air around the electrode patch 100 from the solder (not shown) between the conductive core 1140 of the conductive pad 114 of the main body 111 of the flexible circuit board 11 and the dielectric element 13, so as to prevent the moisture in the air away from the skin from eroding the solder (not shown) between the main body 111 and the dielectric element 13 of the flexible circuit board 11. The insulating substrate B of the flexible circuit board 11 and the insulating plate 12 perform a dual isolation function, which may extend the lifespan of the electrode patch 100. The gold finger 1132 of the wire portion 113 is exposed to the insulating substrate B.
The conductive traces (not shown) of the flexible circuit board 11 include a conductive trace (not shown) connecting all the conductive cores 1140 of the conductive pads 114 located on each main body portion 111 in series, a conductive trace (not shown) connecting the ground terminals (not shown) of the temperature sensors 14 located on each main body portion 111 in series, and a plurality of conductive traces (not shown) respectively connecting the signal terminals (not shown) of the temperature sensors 14 located on the corresponding main body portions 111 in parallel. The conductive traces (not shown) are electrically connected to the gold fingers 1132 of the wire connecting portion 113 in a one-to-one correspondence.
The backing 2 is in the form of a sheet-like arrangement, which is mainly made of a flexible, gas-permeable insulating material. The backing 2 is a mesh fabric. Specifically, the back lining 2 is a mesh non-woven fabric, has the characteristics of softness, lightness, thinness, moisture resistance and air permeability, and can keep the skin surface of a patient dry after being pasted on the body surface of the patient for a long time. The surface of the backing 2 facing the patient's body surface is further coated with a biocompatible adhesive (not shown) for adhering the backing 2 to the body surface corresponding to the tumor site of the patient. The electrode array 1 is centrally adhered to the backing 2 by a biocompatible adhesive (not shown). The back lining 2 is provided with a threading hole 21 corresponding to the terminal position of the wire connecting part 113. The threading hole 21 is used for one end of the lead 4 to pass through and electrically connect with the wiring portion 113, so as to prevent the lead 4 from being applied between the backing 2 and the skin to affect the close fit between the electrode patch 100 and the skin, and further prevent air from entering between the electrode array 1 and the skin of a human body to increase the impedance between the electrode array 1 and the skin, which leads to the increase of heat generation of the electrode array 1 and the low-temperature scald.
The supporting member 3 is made of a soft material, and can be made of a Polyethylene (PE) material, a PET material, a heat-conducting silica gel sheet, or an insulating material which is formed by compounding polyurethane, polyethylene, a dispersing agent, a flame retardant, carbon fibers and the like, is soft, stable in chemical performance, light in weight, not easy to deform and nontoxic. The support 3 is preferably foam. The support 3 has a plurality of through holes 31 disposed therethrough, the through holes 31 corresponding to the electrode units 10. The support member 3 may be of an integral sheet-like construction, which may improve the overall strength of the electrode patch 100. The through holes 31 are arranged at intervals and are respectively arranged on the support 3 in a shape of surrounding the corresponding electrode unit 10. In the present embodiment, the support 3 is formed by a plurality of support units 30 having the same structure and being independent. The plurality of supporting units 30 are arranged at intervals. Each of the support units 30 surrounds the periphery of a corresponding plurality of the electrode units 10. Each supporting unit 30 has two through holes 31 penetrating therethrough for receiving two adjacent electrode units 10 in the same column. The support 3 is composed of 10 support units 30. The thickness of the support 3 is substantially the same as that of the electrode unit 10, and after the support 3 and the electrode array 1 are applied to the backing 2, the upper surfaces of the support 3 and the electrode unit 10 are substantially flush. In other embodiments, each support unit 30 may be provided with a single larger-sized through hole 31 surrounding the periphery of the plurality of electrode units 10 in the column.
The adhesive member 5 is applied to the support member 3 and the electrode unit 10 on the side away from the backing 2. The adhesive member 5 has double-sided adhesive property, and can keep the skin surface moist and relieve local pressure when being contacted with the skin. The adhesive element 5 is preferably an electrically conductive gel. The shape of the adhesive member 5 is substantially the same as the shape of the support member 3. Since the upper surfaces of the support member 3 and the electrode unit 10 are flush with each other so that the sticker 5 is smoothly laid on the support member 3 and the electrode unit 10.
The electrode patch 100 of the present invention has the open space 15 between the plurality of electrode units 10, so that heat and moisture generated by sweating, which are collected on the surface of the skin to which the electrode patch 100 is applied, can be discharged to the outside air through the open space 15 during the electric field treatment of tumors, thereby preventing skin disorders such as erythema, pruritus, inflammation of hair follicle, pain, pimple, etc.
The present invention is not limited to the above preferred embodiments, but rather should be construed as broadly within the spirit and scope of the invention as defined in the appended claims.

Claims (28)

1. An electrode patch for electric field therapy of tumor comprises a plurality of electrode units for applying alternating electric field to tumor part of patient, a plurality of connecting parts for connecting two adjacent electrode units, and a wiring part connected with the connecting parts, characterized in that: the plurality of electrode units are arranged in at least three rows and four columns, each electrode unit is at least connected with two connecting parts, the plurality of electrode units are arranged at intervals to form a plurality of open spaces between the electrode units, and the wiring parts are arranged in a manner of penetrating through one open space.
2. The electrode patch as claimed in claim 1, wherein the spacing between two adjacent electrode units in the same row is the same.
3. The electrode patch as claimed in claim 2, wherein the spacing between two adjacent electrode units in the same row is 8mm to 22 mm.
4. The electrode patch as claimed in claim 1, wherein the spacing between two adjacent electrode units in the same column is the same.
5. The electrode patch as claimed in claim 4, wherein the spacing between two adjacent electrode units in the same column is 6.5mm to 25 mm.
6. The electrode patch as claimed in claim 1, wherein the pitch between two adjacent electrode units located in adjacent rows and adjacent columns and arranged diagonally is the same.
7. The electrode patch as claimed in claim 6, wherein the spacing between two adjacent electrode units located in adjacent rows and adjacent columns and arranged diagonally is 19mm to 33.3 mm.
8. The electrode patch as claimed in claim 1, wherein the electrode unit is in a circular sheet-like configuration having a diameter of approximately 21mm-22 mm.
9. The electrode patch as claimed in claim 1, wherein the plurality of electrode units are spaced apart over an area of 242mm x 166mm at the maximum.
10. The electrode patch as claimed in claim 9, wherein the plurality of electrode units are spaced apart over an area of at least 166mm x 103.5 mm.
11. The electrode patch as claimed in claim 1, wherein the connection part has a width of 4.5mm to 6 mm.
12. The electrode patch as claimed in claim 11, wherein the width of the connection portion is 4.5 mm.
13. The electrode patch according to claim 1, wherein at least two adjacent electrode units in a same row or a same column are arranged in a disconnected manner, and a gap C is formed between the two adjacent electrode units arranged in the disconnected manner.
14. The electrode patch as claimed in claim 13, wherein the wire portion passes through the space C.
15. The electrode patch as claimed in claim 14, wherein the wire portion is laterally extended in the direction of the interval C by a connection portion.
16. The electrode patch as claimed in claim 14, wherein the wire portion is provided substantially in a line shape.
17. The electrode patch as claimed in claim 14, wherein the connection portion is bridged between two connection portions respectively connected to two electrode units disposed in a spaced-apart manner.
18. The electrode patch as claimed in claim 17, wherein the wire portion is provided in a substantially "T" shape.
19. The electrode patch as claimed in claim 17, wherein the wire portion includes a bridge section bridging between the two connection portions and a wire section extending from the bridge section toward the space C.
20. The electrode patch as claimed in claim 19, wherein the bridge section of the connection portion is disposed perpendicularly to the two connection portions connected thereto, and the connection section of the connection portion is disposed perpendicularly to the bridge section.
21. The electrode patch as claimed in claim 19, wherein the bridge section of the terminal portion has a width of 4.5mm to 6mm, and the terminal section of the terminal portion has a width of 4mm to 8 mm.
22. The electrode patch as claimed in claim 1, wherein the number of the electrode units is 20, and the electrode units are distributed in an array area surrounded by four rows and six columns.
23. The electrode patch as claimed in claim 22, wherein the 20 electrode units are distributed in an array area of four rows and six columns in such a manner that the first row and the last row are respectively provided with four electrode units, and the middle two rows are respectively provided with six electrode units.
24. The electrode patch of claim 23, wherein the largest open space of the plurality of open spaces has an area of approximately 4428mm2。
25. The electrode patch of claim 24, wherein the smallest of the plurality of open spaces has an area of approximately 452mm2。
26. The electrode patch as claimed in any one of claims 1 to 25, further comprising a wire welded to the terminal portion.
27. The electrode patch as claimed in claim 26, further comprising a backing supporting the plurality of electrode units, the backing being provided with threading holes through which wires are passed.
28. An electric field treatment apparatus comprising an electric field generator and an electrode patch according to any one of claims 1 to 27 electrically connected to the electric field generator.
CN202111578531.5A 2021-09-28 2021-12-22 Electric field therapeutic instrument and electrode patch thereof Active CN114099954B (en)

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CN202111578531.5A CN114099954B (en) 2021-12-22 2021-12-22 Electric field therapeutic instrument and electrode patch thereof
PCT/CN2022/134677 WO2023051845A1 (en) 2021-09-28 2022-11-28 Tumor electric field treatment system
PCT/CN2022/134717 WO2023051846A1 (en) 2021-09-28 2022-11-28 Tumor electric field treatment system

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023051846A1 (en) * 2021-09-28 2023-04-06 江苏海莱新创医疗科技有限公司 Tumor electric field treatment system
WO2024155827A1 (en) * 2023-01-18 2024-07-25 Somnial Inc. Treatment of tissue using electrical stimulation

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004207267A (en) * 2002-12-20 2004-07-22 Matsushita Electric Ind Co Ltd Semiconductor device and manufacturing method therefor
CN102389618A (en) * 2004-12-07 2012-03-28 斯坦顿有限公司 Electrodes for applying an electric field in-vivo over an extended period of time
CN112007840A (en) * 2016-01-18 2020-12-01 奥赛拉公司 Compact ultrasonic device having annular ultrasonic array peripherally electrically connected to flexible printed circuit board and method of assembling same
CN113008403A (en) * 2021-02-08 2021-06-22 清华大学 Electric field generating device and temperature measuring electrode device
CN113180629A (en) * 2021-04-23 2021-07-30 上海交通大学 Optical genetics self-adaptive tachycardia suppression system based on negative resistance material
CN113509646A (en) * 2021-08-13 2021-10-19 杭州维纳安可医疗科技有限责任公司 Electrode patch, cell division inhibition device and control method thereof
CN113577535A (en) * 2021-09-14 2021-11-02 河北普尼医疗科技有限公司 Novel electrode array for electric field treatment of tumors
CN113749762A (en) * 2021-08-27 2021-12-07 江苏海莱新创医疗科技有限公司 High heat radiation performance electrode

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004207267A (en) * 2002-12-20 2004-07-22 Matsushita Electric Ind Co Ltd Semiconductor device and manufacturing method therefor
CN102389618A (en) * 2004-12-07 2012-03-28 斯坦顿有限公司 Electrodes for applying an electric field in-vivo over an extended period of time
CN112007840A (en) * 2016-01-18 2020-12-01 奥赛拉公司 Compact ultrasonic device having annular ultrasonic array peripherally electrically connected to flexible printed circuit board and method of assembling same
CN113008403A (en) * 2021-02-08 2021-06-22 清华大学 Electric field generating device and temperature measuring electrode device
CN113180629A (en) * 2021-04-23 2021-07-30 上海交通大学 Optical genetics self-adaptive tachycardia suppression system based on negative resistance material
CN113509646A (en) * 2021-08-13 2021-10-19 杭州维纳安可医疗科技有限责任公司 Electrode patch, cell division inhibition device and control method thereof
CN113749762A (en) * 2021-08-27 2021-12-07 江苏海莱新创医疗科技有限公司 High heat radiation performance electrode
CN113577535A (en) * 2021-09-14 2021-11-02 河北普尼医疗科技有限公司 Novel electrode array for electric field treatment of tumors

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023051846A1 (en) * 2021-09-28 2023-04-06 江苏海莱新创医疗科技有限公司 Tumor electric field treatment system
WO2024155827A1 (en) * 2023-01-18 2024-07-25 Somnial Inc. Treatment of tissue using electrical stimulation

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