CN114099962A

CN114099962A - Tumor electric field treatment system and electrode plate assembly thereof

Info

Publication number: CN114099962A
Application number: CN202111580142.6A
Authority: CN
Inventors: 张军; 孙虎; 于晶; 孙义冬
Original assignee: Jiangsu Hailai Xinchuang Medical Technology Co Ltd
Current assignee: Jiangsu Hailai Xinchuang Medical Technology Co Ltd
Priority date: 2021-12-22
Filing date: 2021-12-22
Publication date: 2022-03-01
Also published as: CN116920275A

Abstract

The invention provides a tumor electric field treatment system and an electrode plate assembly thereof, which are used for tumor electric field treatment. The electrode plate of the electrode plate assembly is detachably inserted with the electric connector through the first lead, and the electrode plate only comprises one electrode unit, so that when the electrode unit is damaged and cannot work, only the damaged electrode plate is replaced, and the tumor treatment cost of a patient is reduced; the electrode sheet assembly can be freely combined in quantity and adjusted in position according to the tumor part, the tumor position and the tumor size of a patient, the coverage area of the electrode sheet assembly for tumor electric field treatment is ensured, the electric field intensity of the electrode sheet assembly for tumor electric field treatment is ensured, and the treatment effect is improved.

Description

Tumor electric field treatment system and electrode plate assembly thereof

Technical Field

The invention relates to an electric field tumor treatment system and an electrode plate assembly thereof, belonging to the technical field of medical instruments.

Background

At present, the treatment modes of tumors mainly comprise operations, radiotherapy, chemotherapy and the like, but the methods have corresponding defects, for example, radiotherapy and chemotherapy can generate side effects and kill normal cells. The electric field therapy of tumor is one of the current development fronts, and the electric field therapy of tumor generates a tumor therapy method which interferes the mitosis process of tumor cells through a low-intensity, medium-high frequency and alternating electric field by a special electric field generating device. Research shows that the electric field treatment has obvious effect in treating diseases such as glioblastoma, non-small cell lung cancer, malignant pleural mesothelioma and the like, and the electric field applied by the treatment method can influence the aggregation of tubulin, prevent spindle formation, inhibit mitosis process and induce cancer cell apoptosis.

The conventional electric field treatment system for tumor generally comprises an electric field generator and two pairs of electrode sheet assemblies electrically connected with the electric field generator and attached to the body surface of the tumor part of the patient. The electric field generator generates alternating voltage required by tumor electric field treatment, applies the alternating voltage to the two pairs of electrode sheet assemblies electrically connected with the electric field generator, and further applies the alternating electric field to the patient for tumor electric field treatment through the electrode sheet assemblies adhered to the corresponding body surface of the tumor part of the patient. Each conventional electrode sheet assembly includes a flexible circuit board, a plurality of ceramic sheets disposed on the flexible circuit board, and a lead electrically connected to the flexible circuit board, as disclosed in chinese patent publication No. 11271272 or No. 113164745. The flexible circuit board comprises a flexible substrate, a plurality of paths of conductive traces embedded in the flexible substrate and a plurality of conductive pads exposed on the flexible substrate and electrically connected with the same conductive trace. The ceramic plates are arranged on the flexible circuit board by being welded with the corresponding conductive discs and are connected in series through a conductive trace electrically connected with all the conductive discs. One end of the lead is electrically connected with the flexible circuit board, and the other end of the lead is provided with a plug which can be inserted with the electric field generator.

Above-mentioned tumour electric field treatment system's electrode slice subassembly is pegged graft with electric field generator through the plug of locating its wire one end and is realized the electric connection between electrode slice subassembly and the electric field generator, and then transmit the alternating current signal that electric field generator produced to the flexible circuit board through the wire, the rethread flexible circuit board transmits alternating current signal to each electrically conductive dish with the equal electric connection's of all electrically conductive dishes conducting trace all the way, and then transmit alternating current signal to all potsherds through this way conducting trace series connection together simultaneously through electrically conductive dish, thereby exert alternating electric field to patient's tumour position through a plurality of potsherds on locating the flexible circuit board and carry out tumour electric field treatment. Although the tumor electric field treatment system can apply an alternating electric field to the tumor part of the patient through a plurality of ceramic plates arranged on the flexible circuit board, because the ceramic plates are connected in series through the same path of conducting trace of the flexible circuit board, the problems that an electric signal cannot be transmitted to the ceramic plates due to the breakage of the path of conducting trace of the flexible circuit board or poor welding of one ceramic plate, an electrode plate assembly is integrally scrapped and cannot be used due to unqualified detection during manufacturing, the manufacturing yield of products is low, the manufacturing cost is increased, and the treatment effect is influenced due to insufficient intensity of the alternating electric field applied to the tumor part of the patient during use can exist; in addition, since the conductive pads on the flexible circuit board are all connected in series through one conductive trace, the flexible circuit board needs to be electrically detected before the ceramic sheet is welded to the flexible circuit board, and the electrical detection needs to be carried out again to confirm one by one after the ceramic sheet is welded to the flexible circuit board, which causes complicated working procedures and low efficiency.

In addition, because the above-mentioned tumor electric field treatment system is used for applying the ceramic wafer of the electrode plate assembly of the alternating electric field to the tumor site of the patient to weld to the flexible circuit board through the conducting pad on the flexible circuit board, the relative position between a plurality of ceramic wafers is fixed and unchangeable, the quantity is also fixed, can't increase or reduce freely, but the position, size that the patient suffers from the tumor are different, also can have the electric field intensity that causes to apply to the tumor site and treat because the quantity of the ceramic wafer that is used for applying the alternating electric field is not enough or some ceramic wafer positions are improper when all adopting above-mentioned electrode plate assembly to treat, or the electric field does not cover the regional problem that influences the therapeutic effect of tumor.

Therefore, there is a need to provide an improved electrode sheet assembly and tumor electric field treatment system to overcome the problems of the prior art.

Disclosure of Invention

The invention provides an electrode plate assembly and a tumor electric field treatment system, wherein the electrode plate assembly can be easily replaced when the electrode plate is damaged, and can be freely combined to ensure the treatment effect.

The electrode plate assembly is realized by the following technical scheme: an electrode plate assembly for electric field therapy of tumor comprises at least one electrode plate capable of applying an alternating electric field and an electric connector detachably connected with the electrode plate, wherein the electrode plate comprises an independent electrode unit and a first lead electrically connected with the electrode unit, and the electrode plate is detachably connected with the electric connector through the first lead.

Further, the plurality of electrode pads are connected in parallel to the electrical connector by respective first wires.

Furthermore, the first lead of the electrode plate is provided with a first plug detachably connected with the electric connector in an inserting mode, and the first plug and the electrode unit are respectively located at two opposite ends of the first lead.

Further, the electric connector is provided with a plurality of sockets which are detachably plugged with the first plugs of the first leads of the corresponding electrode plates.

Furthermore, the electric connector is further provided with a second lead, and the second lead and the plurality of sockets are respectively positioned at two opposite ends of the electric connector.

Further, the second wire has a second plug provided at an end thereof.

Furthermore, the electric connector is provided with a body, and the plurality of sockets and the second lead are respectively arranged at two opposite ends of the body.

Furthermore, the electrode plate further comprises a wiring portion connected with the electrode unit, and the wiring portion is welded with one end, far away from the first plug, of the first lead.

Furthermore, the electrode unit comprises a main body part and a dielectric element welded on one side of the main body part, and the wiring part extends from the main body part in the lateral direction.

Further, the main body part and the wire connecting part of the electrode unit form a flexible circuit board of the electrode sheet.

Furthermore, the electrode unit further comprises at least one temperature sensor, and the temperature sensor is arranged on the main body part and is located on the same side as the dielectric element.

Furthermore, at least one through hole is formed in the middle of the dielectric element, and the temperature sensors are contained in the corresponding through holes of the dielectric element respectively.

Furthermore, the electrode unit further comprises an insulating plate adhered to the side of the main body part far away from the dielectric element.

Furthermore, a heat-shrinkable sleeve is coated on the periphery of the welding position of the first lead and the wiring part.

Further, the first lead is detachably connected with the electrode unit.

Furthermore, the electrode plate comprises a wiring portion electrically connected with the electrode unit, and a butt joint socket is arranged at one end, far away from the electrode unit, of the wiring portion.

Furthermore, one end of the first wire, which is far away from the first plug, is provided with a butt joint plug, and the butt joint plug is detachably connected with the butt joint socket in an inserting mode.

Furthermore, the electrode plate also comprises a backing adhered to the electrode unit, a support piece arranged around the electrode unit and adhered to the backing, and an adhering piece covering the electrode unit and one side of the support piece far away from the backing.

The tumor electric field treatment system is realized by the following technical scheme: an electric field treatment system for tumor comprises an electric field generator and the electrode sheet assembly connected with the electric field generator.

Furthermore, the electrode plate assembly is detachably assembled on the adapter and is electrically connected with the electric field generator through the adapter.

Further, the electrode plate assembly is detachably assembled on the electric field generator.

The electrode plate of the electrode plate assembly is detachably connected with the electric connector in an inserting mode through the first lead, the electrode plate only comprises one electrode unit, the electrode plate with the damaged electrode unit can be replaced when the electrode unit is damaged and cannot work, all the electrode plates do not need to be scrapped, and the cost of tumor treatment of a patient can be reduced. In addition, the electrode slice of the electrode slice assembly can be freely adjusted in quantity and position according to the tumor part, the tumor position and the tumor size of a patient, so that the coverage area of the electrode slice assembly for tumor electric field treatment is ensured, the electric field intensity of the electrode slice assembly for tumor electric field treatment is ensured, and the electric field treatment effect is ensured; meanwhile, the adjustment of the relative positions of the electrode plates can allow the body surface skin of the part of the patient, which is pasted with the electrode plates, to freely breathe, so that the phenomenon that sweat, pores are blocked and skin inflammation is caused due to the fact that heat of the body surface skin corresponding to the tumor part of the patient is accumulated due to long-time treatment is avoided.

Drawings

FIG. 1 is a plan view of an electrode pad assembly of a first embodiment of the electric field tumor treatment system of the present invention.

Fig. 2 is an exploded view of an electrode tab and an electrical connector of the electrode tab assembly shown in fig. 1.

Fig. 3 is an exploded perspective view of the electrode sheet shown in fig. 2.

Fig. 4 is an exploded perspective view of the electrode unit and the first lead of the electrode sheet shown in fig. 3.

Fig. 5 is a plan view of a flexible circuit board of the electrode pad shown in fig. 4.

Fig. 6 is a plan view of an electrode pad assembly of a second embodiment of the electric field tumor treatment system of the present invention.

Fig. 7 is an exploded perspective view of the electrode sheet shown in fig. 6.

FIG. 8 is a schematic block diagram of the electric field tumor therapy system of the present invention.

Description of reference numerals:

tumor electric field treatment system 1000, electrode pad assembly 100, 100 ', electrode pad 1, 1 ', electrode unit 10, 10 ', body portion 101, 101 ', insulating plate 102, 102 ', dielectric element 103, 103 ', perforation 1031, 1031 ', temperature sensor 104, 104 ', conductive disc 105, conductive core 1051, pad 106, first pad 106A, second pad 106B, wire connection portion 11, 11 ', gold finger 111, first lead 12, 12 ', first plug 121, 121 ', heat shrinkable sleeve 122, connector 123 ', docking socket 123A ', docking plug 123B ', backing 13, 13 ', reentrant corner 131 ', support member 14, 14 ', through hole 141,

adhesive member

15, 15 ', electrical connector 2, 2 ', body 20, 20 ', socket 21, 21 ', second lead 22, second plug 221, flexible circuit board 16, 16 ', insulating substrate B, B ', electrical field generator 200, An adaptor 300.

Detailed Description

Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, like numbers in different drawings represent the same or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present invention. Rather, they are merely examples of devices, systems, apparatus, and methods consistent with certain aspects of the invention.

Referring to fig. 1 to 8, an electric field therapy system 1000 for treating tumor according to the present invention includes an electric field generator 200, an adaptor 300 electrically connected to the electric field generator 200, and a plurality of electrode sheet assemblies 100, 100' electrically connected to the electric field generator 200 through the adaptor 300. The electrode sheet assemblies 100, 100' are pasted on the body surface corresponding to the tumor part of the patient, and the treatment electric field generated by the electric field generator 200 is acted on the human body to carry out the tumor electric field treatment. In other embodiments, the electrode plate assembly 100, 100' of the electric field tumor therapy system can be directly plugged into the electric field generator 200 to electrically connect the electric field generator 200 to the electrode plate assembly.

Fig. 1 to 5 show an electrode sheet assembly 100 according to a first embodiment of the present invention. The electrode plate assembly 100 can be directly connected with the electric field generator 200 in an inserting manner to realize the electric connection between the electrode plate assembly and the electric field generator 200, or can be directly connected with the adaptor 300 in an inserting manner, and then is electrically connected with the electric field generator 200 through the adaptor 300 to realize the electric connection between the electrode plate assembly and the electric field generator 200. The electrode plate assembly 100 includes an electrical connector 2 electrically connected to the electric field generator 200 or the adaptor 300, and a plurality of electrode plates 1 detachably assembled to the electrical connector 2. The tumor electric field treatment system 1000 of the present invention generates an alternating electrical signal required for tumor electric field treatment by the electric field generator 200 and transmits the alternating electrical signal to the electrical connector 2 of the electrode plate assembly 100, and then transmits the alternating electrical signal to the plurality of electrode plates 1 electrically connected thereto by the electrical connector 2, and further applies the alternating electric field to the tumor part of the patient by the plurality of electrode plates 1 to perform tumor electric field treatment. Moreover, the electrode plates 1 of the electrode plate assembly 100 are detachably assembled on the electric connector 2, and the electrode plates 1 are connected to the electric connector 2 in parallel, so that the damaged electrode plate 1 can be easily replaced when one electrode plate 1 is damaged and cannot work, and the electrode plates 1 do not need to be scrapped, so that the manufacturing cost can be reduced, the waste can be avoided, and the electrode plates are ensured to have enough electric field intensity during tumor electric field treatment; meanwhile, the electrode plates 1 can be freely combined in quantity and adjusted in position according to the body difference, the tumor part, the tumor size and the like of a patient, so that the electric field intensity applied to the tumor part of the patient is optimal; in addition, the application positions and the intervals of the electrode plates 1 can be freely adjusted according to the self condition of a patient, so that the skin at the tumor part of the patient can be ensured to freely breathe, and the phenomenon that the heat generated at the part of the electrode plates 1 applied to the tumor part of the patient is quickly accumulated and cannot be timely dissipated to cause the body surface of the electrode plates 1 applied to the patient to sweat and block pores to cause skin inflammation due to long-time electric field treatment is avoided.

Please refer to fig. 3 to 5, in which a plurality of electrode plates 1 are detachably inserted into corresponding portions of the electrical connector 2, so as to achieve parallel connection between the electrode plates 1 and the electrical connector 2, and to achieve electrical connection with the electric field generator 200 through the electrical connector 2, so that the electrode plates 1 can be replaced in time and conveniently when damaged, thereby ensuring sufficient electric field strength applied to the tumor portion and improving the therapeutic effect. Each electrode sheet 1 includes an electrode unit 10 for applying an alternating electric field to a tumor region of a patient, a wire connecting portion 11 electrically connected to the electrode unit 10, a first lead 12 welded to the wire connecting portion 11, a backing 13 adhered to the electrode unit 10, a support member 14 adhered to the backing 13 in a shape surrounding the electrode unit 10, and an adhesive member 15 covering the electrode unit 10 and a corresponding portion of the support member 14. One end of the first wire 12 is welded to the wiring portion 11, and the other end is detachably connected to the electrical connector 2 through a first plug 121 disposed at the end of the first wire in an inserting manner, so as to electrically connect the electrode unit 10 to the electrical connector 2, and further transmit an alternating electrical signal generated by the electric field generator 200 to the electrode unit 10 through the electrical connector 2 for tumor electric field treatment. Optionally, the electrode plate 1 may be directly plugged into the electric field generator 200 through the first plug 121 of the first wire 12 or first plugged into the adaptor 300, and then electrically connected to the electric field generator 200 through the adaptor 300 to realize the electrical connection between the electrode plate 1 and the electric field generator 200.

The electrode unit 10 of the electrode tab 1 includes a main body 101 disposed at an end of the wire connecting portion 11 and electrically connected to the wire connecting portion 11, an insulating plate 102 and a dielectric element 103 respectively disposed at two opposite sides of the main body 101, and a temperature sensor 104 disposed on the main body 101 and located at the same side as the dielectric element 103. The electrode unit 10 has a circular sheet-like configuration as a whole. The main body 101, the insulating plate 102, and the dielectric element 103 are all circular sheet-shaped structures, and have substantially the same size and are disposed in one-to-one correspondence along the thickness direction. The centers of the main body 101, the insulating plate 102, and the dielectric element 103 are located on the same straight line.

The main body 101 is provided with a conductive plate 105 on the side facing the skin of the human body. The conductive pads 105 are soldered to the dielectric element 103 to assemble the dielectric element 103 to the body portion 101. The conductive pads 105 can be completely covered by the dielectric element 103 such that the conductive pads 105 are soldered (not shown) to the dielectric element 103 by a solder. The conductive disc 105 is centered on the centerline of the main body 101. The conductive pad 105 includes a plurality of conductive cores 1051 arranged in a central symmetrical manner, which can effectively prevent the dielectric element 103 from being displaced due to stacking of solder (not shown) during the soldering process. The top surfaces of the conductive cores 1051 are located on the same plane, so that cold joint with the dielectric element 103 can be avoided. A pair of soldering pads 106 is further disposed between the plurality of conductive cores 1051, and can be soldered to corresponding portions of the temperature sensor 104 to electrically connect the temperature sensor 104 and the main body 101. The two pads 106 include a first pad 106A and a second pad 106B. The temperature sensor 104 has a signal terminal (not shown) and a ground terminal (not shown). The first pad 106A is soldered to a ground terminal (not shown) of the temperature sensor 104, and the second pad 106B is soldered to a signal terminal (not shown) of the temperature sensor 104.

The insulating plate 102 is made of an insulating material. Preferably, the insulating plate 102 is an epoxy glass cloth laminate. The insulating plate 102 is adhered to the surface of the main body 101 away from the skin of a human body through a sealant (not shown), so that on one hand, the strength of the main body 101 can be enhanced to provide a flat welding plane for the welding operation between the main body 101 and the dielectric element 103; on the other hand, moisture in the air on the side of the electrode sheet 1 away from the skin can be isolated from contacting with solder (not shown) between the main body 101 and the dielectric element 103, so that the moisture can be prevented from corroding the solder (not shown) between the main body 101 and the dielectric element 103 to influence the electrical connection between the main body 101 and the dielectric element 103. The size of the insulating plate 102 is substantially the same as that of the main body 101, so that when the insulating plate 102 is attached to the side, away from the skin of the human body, of the main body 101 through a sealant (not shown), the sealant (not shown) climbs to the side, facing the skin of the human body, of the main body 101 through a capillary effect, and the filling of the sealant (not shown) in a gap (not shown) formed by welding the dielectric element 103 and the main body 101 is affected, so that a cavity exists in the sealant (not shown), and further, the phenomenon that when the sealant (not shown) is cured at a high temperature, because the difference between the water vapor in the cavity and the thermal expansion coefficient of the sealant (not shown) is large, the water vapor rapidly expands to cause bursting, so that popcorn phenomenon is generated, and the product is damaged is avoided.

The dielectric element 103 is made of a high dielectric constant material, and has the conductive characteristics of blocking the conduction of direct current and allowing alternating current to pass through, so that the safety of a user can be ensured during tumor electric field treatment. Preferably, the dielectric element 103 is a dielectric ceramic sheet. A through hole 1031 corresponding to the pair of pads 106 of the main body 101 is provided through the dielectric element 103 to accommodate the temperature sensor 104. A metal layer (not shown) is attached to a surface of the dielectric element 103 facing the body 101. The metal layer (not shown) of the dielectric element 103 and the conductive core 1051 of the conductive pad 105 of the main body 101 are welded point-to-surface, so that high welding alignment accuracy is not required, and welding is facilitated. The inner edge of the metal layer (not shown) of the dielectric element 103 is spaced from the edge of the through hole 1031 of the dielectric element 103, so that the solder (not shown) provided between the metal layer (not shown) of the dielectric element 103 and the main body 101 is prevented from diffusing in the direction of the through hole 1031 of the dielectric element 103 when melted by heat, thereby preventing the temperature sensor 104 from being short-circuited. The outer edge of the metal layer (not shown) of the dielectric element 103 and the outer edge of the dielectric element 103 are also spaced apart from each other, so that it is possible to prevent the solder (not shown) provided between the metal layer (not shown) of the dielectric element 103 and the main body 101 from overflowing to the outside of the main body 101 when melted by heat, and thus, when the electrode sheet 1 is applied to the surface of the tumor site of the patient, the direct current that is not blocked by the dielectric element 103 passes through and acts on the surface of the tumor site of the patient.

A gap (not shown) formed by welding the dielectric element 103 and the main body 101 is filled with a sealant (not shown) to protect a soldering tin (not shown) between the dielectric element 103 and the main body 101, so as to prevent the dielectric element 103 from being influenced by an external force to cause the welding part to break, and further cause that an alternating electric field cannot be applied to the tumor part of the patient through the dielectric element 103; meanwhile, it is avoided that moisture in the air enters the gap (not shown) to erode solder (not shown) between the dielectric element 103 and the main body 101, thereby affecting the electrical connection between the dielectric element 103 and the main body 101. The outer diameter of the dielectric element 103 is slightly smaller than the diameter of the main body 101, so that when the sealant (not shown) is filled, the sealant (not shown) can be filled into the gap (not shown) along the edge of the main body 101 located outside the dielectric element 103 through capillary phenomenon, which is beneficial to filling the sealant (not shown) in the gap (not shown) formed by welding the dielectric element 103 and the main body 101. When the sealant (not shown) is filled in the gap (not shown) formed by welding the dielectric element 103 and the body 101, air in the gap (not shown) can be discharged from the through hole 1031 of the dielectric element 103, so that the sealant (not shown) filled in the gap (not shown) is prevented from generating a cavity, and the product quality is improved.

The temperature sensor 104 is soldered to a first land 106A provided on the main body 101 via a ground terminal (not shown) thereof and to a second land 106B provided on the main body 101 via a signal terminal (not shown) thereof. The temperature sensor 104 is welded to the body 101 and then accommodated in the through hole 1031 of the dielectric element 103. Preferably, the temperature sensor 104 is a thermistor. The temperature sensor 104 is used for monitoring the temperature of the adhesive member 15 covering the side of the dielectric member 103 of the electrode unit 10 facing the skin of the human body, and further detecting the temperature of the skin of the human body to which the adhesive member 15 is attached. When the temperature monitored by the temperature sensor 104 exceeds the upper limit of the human body safe temperature, the tumor electric field treatment system 1000 can timely reduce or turn off the alternating voltage applied to the electrode plate 1 by the electric field generator 200 so as to avoid low-temperature scald of the human body. The temperature sensor 104 is soldered to the main body 101 through a pair of soldering pads 106 of the main body 101 and then sealed with a sealant (not shown) to prevent moisture from attacking the temperature sensor 104 and causing the temperature sensor 104 to fail.

The wire connecting portion 11 extends laterally from the main body portion 101 of the electrode unit 10. The periphery of the welding position of the wire connecting portion 11 and the first lead 12 is covered with a heat-shrinkable sleeve 122. The heat-shrinkable sleeve 122 performs insulation protection on the joint of the first lead 12 and the wiring portion 11, provides support, prevents the joint of the first lead 12 and the wiring portion 11 from being broken, and is dustproof and waterproof.

The main body portion 101 of the electrode unit 10 and the wire connection portion 11 together constitute the flexible circuit board 16 of the electrode tab 1. From the perspective of forming the electrode unit 10, the insulating plate 102 is disposed on the side of the main body portion 101 of the flexible circuit board 16 facing away from the skin of the human body, the dielectric element 103 is disposed on the side of the main body portion 101 of the flexible circuit board 16 facing the skin of the human body, and the temperature sensor 104 is disposed on the side of the main body portion 101 of the flexible circuit board 16 facing the skin of the human body.

The flexible circuit board 16 includes an insulating substrate B and a plurality of conductive traces (not shown) embedded in the insulating substrate B, that is, the main body 101 and the wire connecting portion 11 of the electrode unit 10 are both configured of the insulating substrate B and the plurality of conductive traces (not shown) embedded in the insulating substrate B. The plurality of conductive traces (not shown) in the insulating substrate B of the main body portion 101 are electrically connected to the corresponding plurality of conductive traces (not shown) in the insulating substrate B of the wire connecting portion 11, respectively. In this embodiment, the flexible circuit board 16 has three paths of conductive traces (not shown), including one conductive trace (not shown) connecting all the conductive cores 1051 of the conductive pads 105 of the main body 101 in series, one conductive trace (not shown) electrically connected to a ground terminal (not shown) of the temperature sensor 104 on the main body 101, and one conductive trace (not shown) electrically connected to a signal terminal (not shown) of the temperature sensor 104 on the main body 101. The side of the wire connecting part 11 facing the skin of the human body is provided with three golden fingers 111. The three gold fingers 111 of the wire connection portion 11 are electrically connected to three conductive traces (not shown), respectively. The three gold fingers 111 of the wire connecting portion 11 are welded to one end of the first lead 12 away from the first plug 121, so as to electrically connect the main body portion 101 of the electrode unit 10 and the first lead 12, and further electrically connect the dielectric element 103 and the temperature sensor 104 with the first lead 12 through the main body portion 101.

The conductive core 1051 is exposed to the insulating substrate B of the main body 101. The insulating substrate B of the flexible circuit board 16 can isolate moisture in the air around the electrode sheet 1 from solder (not shown) between the conductive pad 105 and the dielectric element 103, so as to prevent moisture in the air away from the skin from eroding the solder (not shown) between the conductive pad 105 and the dielectric element 103 on the main body 101 of the flexible circuit board 16. The insulating substrate B of the flexible circuit board 16 and the insulating plate 102 play a dual-isolation role, so that the service life of the electrode plate 1 can be prolonged.

The backing 13 is in the form of a sheet-like arrangement, which is mainly made of a flexible, gas-permeable insulating material. The backing 13 is a mesh fabric. Specifically, the backing 13 is a mesh nonwoven fabric, has the characteristics of softness, lightness, thinness, moisture resistance and air permeability, and can keep the skin surface of the patient dry after being pasted on the body surface of the patient for a long time. The surface of the backing 13 facing the patient's body surface is further coated with a biocompatible adhesive (not shown) for adhering the backing 13 closely to the body surface corresponding to the tumor site of the patient. In the present embodiment, only one electrode unit 10 is adhered to the backing 13. The backing 13 is of a generally square sheet-like configuration. The four corners of the backing 13 are rounded corner-shaped.

The support 14 is adhered to the backing 13 and surrounds the outside of the electrode unit 10. A through hole 141 is formed through the support 14 to receive the electrode unit 10. The support 14 may be made of a foam material. The support 14 is flush with the surface of the electrode unit 10 on the side remote from the backing 13. That is, the support member 14 is flush with the surface of the electrode unit 10 on the side facing the adhesive 15.

The adhesive member 15 has double-sided adhesive properties. One surface of the adhesive member 15 is adhered to the support member 14 and the surface of the electrode unit 10 on the side away from the backing 13. The other side of the adhesive member 15 is used as a coating layer and is applied to the skin of the human body surface to keep the skin surface moist and relieve local pressure. Preferably, the adhesive member 15 may employ a conductive hydrogel to serve as a conductive medium. The adhesive member 15 has better application to the skin of the human body under the supporting action of the supporting member 14.

Referring to fig. 1 to 2, the electrical connector 2 is provided with a plurality of sockets 21 for receiving the first plugs 121 of the first wires 12 of the corresponding electrode pads 1, and a second wire 22 for receiving the adaptor 300 or the electric field generator 200. The end of the second wire 22 away from the electrical connector 2 is provided with a second plug 221, which can be directly inserted into the electric field generator 200 or inserted into the adaptor 300, and then inserted into the electric field generator 200 through the adaptor 300 to realize the electrical connection between the electric field generator 200 and the electric field generator 200. The plurality of sockets 21 and the second wires 22 are respectively disposed at two opposite ends of the electrical connector 2. The electric connector 2 is inserted into the first plug 121 of the first lead 12 of the electrode plate 1 through the socket 21 thereof, so as to connect the electrode plates 1 to the electric connector 2 respectively to realize the electric connection between the electrode plates 1 and the electric connector 2, and further realize the electric connection between the electrode plates 1 and the electric field generator 200 through the second plug 221 inserted into the electric field generator 200 or the adaptor 300. When the electric field generator is used, the electrode plates 1 are attached to the corresponding body surface of a tumor part of a patient, the electrode plates 1 are inserted into the corresponding sockets 21 of the electric connector 2 through the first plugs 121 of the electrode plates, and the electric connector 2 is electrically connected with the electric field generator 200 through the second plugs 221 of the electric connector, so that an alternating electric field generated by the electric field generator 200 is transmitted to the electrode plates 1 through the electric connector 2, and acts on the tumor part of the patient through the electrode plates 1 to interfere or prevent the mitosis of tumor cells of the patient, and the purpose of treating tumors is achieved. The electrode plate 1 of the electrode plate assembly 100 is detachably inserted into the electric connector 2, the electrode plate 1 only comprises one electrode unit 10, each electrode unit 10 is electrically connected with the electric field generator 200 through a first lead 12 electrically connected with the electrode unit 10, and when the electrode unit 10 or the first lead 12 is damaged and cannot work, only the corresponding electrode plate 1 needs to be replaced, so that the cost of tumor treatment of a patient can be reduced. The number of the electrode plates 1 of the electrode plate assembly 100 can be freely combined according to the tumor position and the tumor size of a patient, so that the coverage area of the electrode plate assembly 100 for tumor electric field treatment is ensured, the electric field intensity of the electrode plate assembly 100 for tumor electric field treatment is ensured, and the tumor electric field treatment effect is improved. In addition, the relative positions of the electrode plates 1 of the electrode plate assembly 100 can be freely adjusted according to the body difference, the tumor positions and the tumor sizes of the patients, so that the optimal electric field intensity and electric field coverage area for tumor treatment can be obtained, and meanwhile, the skin on the body surface of the patient, which is pasted with the electrode plates 1, can freely breathe, so that the phenomenon that the heat on the body surface of the patient cannot be timely dissipated due to the fact that the tumor electric field treatment is carried out for a long time, and the skin inflammation caused by sweat blocking pores is avoided.

In the present embodiment, the number of the sockets 21 of the electrical connector 2 is 9, and the number of the electrode tabs 1 is 9. The electrical connector 2 is provided with a body 20, the body 20 being of a substantially polyhedral configuration. In the present embodiment, the body 20 has a generally hexagonal prism configuration. The 9 sockets 21 are respectively arranged on a plurality of adjacent side surfaces of the body 20, and an obtuse angle is formed between the adjacent side surfaces. The second lead 22 is disposed on a side of the body 20 away from the socket 21. In the present embodiment, 9 sockets 21 are equally disposed on 3 adjacent side surfaces of the body 20, and each 3 sockets 21 are disposed on the same side surface of the body 20 of the electrical connector 2. Terminals (not shown) in the 9 sockets 21 of the electrical connector 2 may be connected in series so that the 9 electrode tabs 1 are connected in series. Terminals (not shown) in the 9 sockets 21 of the electrical connector 2 may be connected in parallel so that the 9 electrode tabs 1 are connected in parallel. When terminals (not shown) in the socket 21 of the electrical connector 2 are connected in series, all the electrode tabs 1 need to be inserted into the electrical connector 2 for use. When the terminals (not shown) in the socket 21 of the electrical connector 2 are connected in parallel, a part of the electrode plate 1 can be selected to be plugged into the electrical connector 2 according to requirements, so that the use is more convenient and flexible. Alternatively, the terminals (not shown) in the 9 sockets 21 of the electrical connector 2 may be connected partially in series and partially in parallel. Terminals (not shown) in the socket 21 of the electrical connector 2 may be connected in series, in parallel, partially in series, or partially in parallel as needed, so that the plurality of electrode tabs 1 connected to the electrical connector 2 are connected in series, in parallel, partially in series, or partially in parallel. When the size of the tumor is large, a proper number of electrode plates 1 can be selected and the interval between the electrode plates 1 can be freely adjusted according to the requirement, so that the coverage area and the electric field treatment effect of the electrode plate assembly 100 for tumor electric field treatment can be ensured. When the tumor position is deviated to one side of the corresponding part of the body, the body surface corresponding to one side far away from the tumor can properly increase the number of the electrode plates 1 of the electrode plate assembly 100 for pasting, so as to enhance the electric field intensity of one side far away from the tumor.

Fig. 6 and 7 disclose an electrode sheet assembly 100 ' according to a second embodiment of the present invention, which also includes a plurality of electrode sheets 1 ' for applying an alternating electric field to a tumor site of a patient and an electrical connector 2 ' electrically connected to an adaptor 300 or an electric field generator 200. The electrode plates 1 'are detachably assembled on the electric connector 2' in an inserting manner so as to realize the electric connection between the electrode plates and the electric connector 2 ', and further realize the electric connection between the electrode plates and the electric field generator 200 through the electric connector 2'. Each electrode tab 1 'includes an electrode unit 10', a connection portion 11 'connected to the electrode unit 10', a first lead 12 'welded to the connection portion 11', a backing 13 'adhered to the electrode unit 10', a support member 14 'surrounding the electrode unit 10' and adhered to the backing 13 ', and an adhesive member 15' covering the electrode unit 10 'and the support member 14'. The electrode sheet assembly 100' differs from the electrode sheet assembly 100 of the first embodiment in that: the electrode pad assembly 100 ' includes 3 electrode pads 1 ', the body 20 ' of the electrical connector 2 ' is substantially in a triangular prism configuration, the electrical connector 2 ' is provided with 3 sockets 21 ', and the 3 sockets 21 ' are all disposed on the same side of the body 20 ' of the electrical connector 2 '. The connection portion 11 ' of each electrode plate 1 ' is detachably connected with the corresponding first lead 12 ' in an inserting manner. The connection portion 11 'of the electrode plate 1' is electrically connected to the first lead 12 'through a connector 123'. The connector 123 ' includes a pair of sockets 123A ' and a pair of plugs 123B '. The mating receptacle 123A ' is connected to the wire connecting portion 11 ', and the mating plug 123B ' is connected to an end of the first conductor 12 ' remote from the first plug 121 '. Also, the mating receptacle 123A ' is provided at the end of the wire connecting portion 11 ', and the mating plug 123B ' is provided at the end of the first wire 12 ' remote from the first plug 121 '. The docking socket 123A ' and the electrode unit 10 ' are located at opposite ends of the wire connection part 11 ', respectively. The mating plug 123B ' and the first plug 121 ' are respectively disposed at two opposite ends of the first wire 12 '. When the electrode unit 10 ' of the electrode plate 1 ' cannot work due to damage, only the part of the electrode plate 1 ' except the first lead 12 ' can be replaced, and the first lead 12 ' can be continuously used, so that the tumor treatment cost of a patient is further reduced.

The backing 13 'of the electrode sheet 1' is substantially of a "convex" configuration. The backing 13 'has two concave corners 131' recessed inwardly from two corners thereof, respectively. The two recessed corners 131 ' are located at two corners of the backing 13 ' away from the wire connecting portion 11 ', respectively. The concave angle 131 'at the corner of the backing 13' is communicated with the outside and is arranged in an L shape. The included angle between the two side edges of the concave angle 131 ' formed by the back lining 13 ' is greater than or equal to 90 degrees, so that when the electrode plate 1 ' is pasted on the body surface corresponding to the tumor position of a patient, the corner of the back lining 13 ' is prevented from being arched to cause wrinkles, and further, air enters the space between the electrode unit 10 ' and the skin from the wrinkles to increase the impedance between the electrode unit 10 ' and the skin, so that the heat of the electrode unit 10 ' is increased to cause low-temperature scald.

The electrode unit 10' has a substantially square sheet-like configuration. The main body 101 ', the insulating plate 102', and the dielectric element 103 'of the electrode unit 10' are all square sheet-shaped. Two temperature sensors 104 ' are provided on the side of the main body 101 ' where the dielectric element 103 ' is provided. The dielectric element 103 ' is provided with two through holes 1031 ' that respectively receive the temperature sensors 104 '. The two temperature sensors 104 'are symmetrically arranged on the main body part 101', so that the temperature of the human skin corresponding to different positions can be detected, and the accuracy of the detected data is ensured. Four conductive traces (not shown) are embedded in the insulating substrate B ' of the flexible circuit board 16 ' formed by the main body portion 101 ' of the electrode unit 10 ' and the wire connection portion 11 '. The four conductive traces (not shown) of the flexible circuit board 16 ' are respectively a conductive trace (not shown) connecting all the conductive cores (not shown) of the conductive pads (not shown) of the main body 101 ' in series, a conductive trace (not shown) connecting the ground terminals (not shown) of the two temperature sensors 104 ' on the main body 101 ' in series, and two conductive traces (not shown) connecting the signal terminals (not shown) of the two temperature sensors 104 ' in parallel. The wire connection portion 11' is provided with four gold fingers (not shown) on a side facing the skin of the human body. The four conductive traces (not shown) are electrically connected to four gold fingers (not shown) of the wire connection portion 11'.

At least one electrode plate 1, 1 'of the electrode plate assembly 100, 100' of the present invention is detachably inserted into the electric field generator 200 through the first lead 12, 12 'disposed thereon, or is detachably inserted into the adaptor 300, and then is electrically connected to the electric field generator 200 through the adaptor 300, or is detachably inserted onto the electric connector 2, 2', and then is electrically connected to the electric field generator 200 through the electric connector 2, 2 ', so as to realize the electrical connection between the electrode plate and the electric field generator 200, and each electrode plate 1, 1' only includes one electrode unit 10, 10 'electrically connected to the corresponding first lead 12, 12', when the electrode unit 10, 10 'is damaged and cannot work, only the corresponding electrode plate 1, 1' needs to be replaced, so as to reduce the cost of tumor treatment for the patient. In addition, the electrode plate assemblies 100 and 100 'of the invention can freely combine the number of the electrode plates 1 and 1' or freely adjust the positions of the electrode plates according to the tumor position, the tumor position and the tumor size of a patient, so as to ensure the coverage area of the electrode plate assemblies 100 and 100 'for tumor electric field treatment, ensure the electric field intensity of the electrode plate assemblies 100 and 100' for tumor electric field treatment and improve the electric field treatment effect; meanwhile, the relative interval between the electrode plates 1 and 1' can allow the skin of the patient to freely breathe and exchange heat with the outside air, so that the skin diseases caused by sweat and pore blockage due to the accumulation of heat on the body surface of the patient after long-time electric field treatment are avoided.

The present invention is not limited to the above preferred embodiments, but rather should be construed as broadly within the spirit and scope of the invention as defined in the appended claims.

Claims

1. An electrode plate assembly for electric field therapy of tumor comprises at least one electrode plate capable of applying an alternating electric field and an electric connector detachably connected with the electrode plate, wherein the electrode plate comprises an independent electrode unit and a first lead electrically connected with the electrode unit, and the electrode plate is detachably connected with the electric connector through the first lead.

2. The electrode pad assembly of claim 1, wherein a plurality of electrode pads are connected in parallel to the electrical connector by respective first wires.

3. An electrode strip assembly according to claim 1 or 2, wherein the first conductor of the electrode strip has a first plug for detachably engaging with the electrical connector, the first plug and the electrode unit being located at opposite ends of the first conductor.

4. The electrode tab assembly of claim 3 wherein the electrical connector has a plurality of sockets for removably receiving the first plugs of the first wires of the respective electrode tabs.

5. The electrode tab assembly of claim 4 wherein the electrical connector is provided with a second wire, the second wire and the plurality of receptacles being located at opposite ends of the electrical connector.

6. The electrode tab assembly of claim 5 wherein the second lead has a second plug disposed at an end thereof.

7. The electrode sheet assembly of claim 6, wherein the electrical connector has a body, and the plurality of sockets and the second wire are disposed at opposite ends of the body.

8. The electrode tab assembly of claim 3 wherein the electrode tab further comprises a wire connecting portion to the electrode unit, the wire connecting portion being welded to an end of the first wire remote from the first plug.

9. The electrode tab assembly of claim 8 wherein the electrode unit includes a body portion and a dielectric member welded to one side of the body portion, the wire connecting portion extending laterally from the body portion.

10. The electrode tab assembly of claim 9, wherein the main body portion and the terminal portion of the electrode unit constitute a flexible circuit board of the electrode tab.

11. The electrode pad assembly of claim 9, wherein the electrode unit further comprises at least one temperature sensor disposed on the same side of the body portion as the dielectric element.

12. The electrode sheet assembly of claim 11, wherein the dielectric member has at least one through hole formed therein, and the temperature sensors are received in the corresponding through holes of the dielectric member.

13. The electrode sheet assembly of claim 9, wherein the electrode unit further comprises an insulating sheet adhered to a side of the main body portion remote from the dielectric element.

14. The electrode tab assembly of claim 8 wherein the periphery of the junction of said first wire and said wire connecting portion is covered with a heat shrink sleeve.

15. The electrode tab assembly of claim 3 wherein the first lead is removably connected to the electrode unit.

16. An electrode sheet assembly according to claim 15, wherein the electrode sheet includes a terminal portion electrically connected to the electrode unit, and a docking socket is provided at an end of the terminal portion remote from the electrode unit.

17. The electrode tab assembly of claim 16 wherein an end of the first wire remote from the first plug is provided with a mating plug which removably mates with the mating receptacle.

18. The electrode sheet assembly of claim 1, further comprising a backing adhered to the electrode unit, a support member disposed around the electrode unit and adhered to the backing, and an adhesive member covering the electrode unit and the support member on a side away from the backing.

19. An electric field tumor treatment system comprising an electric field generator and an electrode sheet assembly according to any one of claims 1 to 18 connected to the electric field generator.

20. The electric field tumor therapy system according to claim 19, further comprising an adapter electrically connected to said electric field generator, wherein said electrode sheet assembly is detachably assembled to said adapter and electrically connected to said electric field generator through said adapter.

21. The electrical field tumor treatment system of claim 19, wherein said electrode pad assembly is removably assembled to said electrical field generator.