CN111481823A

CN111481823A - Device for treating multiple organ tumors based on electric field

Info

Publication number: CN111481823A
Application number: CN202010376458.2A
Authority: CN
Inventors: 段红杰; 刘胜军; 张建义
Original assignee: Hebei Puni Medical Technology Co ltd
Current assignee: Hebei Puni Medical Technology Co ltd
Priority date: 2020-05-07
Filing date: 2020-05-07
Publication date: 2020-08-04
Also published as: DE202020106283U1

Abstract

The invention relates to a device for treating multiple organ tumors based on an electric field, comprising: the electric field generating device is used for outputting alternating current signals with adjustable voltage waveform, amplitude and frequency; one end of the lead is connected with the electric field generating device, and the other end of the lead is connected with the field energy electrode patch; the field energy electrode patch comprises a flexible substrate and a plurality of electrode plate bodies made of insulating capacitor materials, wherein the electrode plate bodies are arranged on the substrate in an array mode, can effectively excite an electric field and avoid generation of conduction current, and are connected with the conducting wires; a wearable device, a plurality of the field energy electrode patches arranged inside the wearable device; the wearable device comprises one or more of hat, waistcoat, bra and shorts in any combination.

Description

Device for treating multiple organ tumors based on electric field

Technical Field

The invention relates to an electric field applying device for selectively inhibiting the growth of specific cells, in particular to a device for treating multi-organ tumors based on an electric field.

Background

The electric field tumor therapy is a method for treating tumors by electrically polarizing a device part consisting of a plurality of capacitance electrodes by using low-intensity low-frequency electrostatic waves. See patent No. 201820261308.5 for Chinese invention.

The response of living cells to an applied alternating electric field is frequency dependent based on the biological effects of the electric field on the cells and living tissue. At low frequencies (below 1 khz), alternating electric fields can stimulate nerves and muscles by depolarizing cell membranes. In addition, low frequency or pulsed electric fields can also accelerate fracture healing. At high frequencies (frequencies above 10 mhz), the alternating electric field can cause tissue heating, which can be used for tumor ablation.

In recent years, research and clinical application show that when the frequency of the electric field is in the range of 100-. Such studies have subsequently led to the development of new electric field therapies in the field of tumor therapy. Specific techniques have been used in some countries for medical research and clinical treatment of brain tumors and other cancers. It has been shown in particular that the application of alternating electric fields of low intensity and medium frequency can inhibit the mitotic growth of active tumor cells by disrupting mitosis. In addition, finite element modeling calculations have also demonstrated that the application of an electric field can affect the division and growth of tumor cells.

Under alternating electric field conditions, different electric dipoles rotate due to the alternating electric field direction. In contrast to tumor cells, normal cells have a different dielectric response due to their different local chemical composition inside them corresponding to different electric dipoles. For example, the chemical bond details of the DNA strands of normal cells differ from those of tumor cells, meaning that the DNA strands of two cells will respond with different dielectric responses. Experimental evidence has shown that an alternating electric field at a specific frequency can cause the breakage and destruction of DNA bonds inside tumor cells, and thus cause the death of the tumor cells, but the applied electric field has no obvious influence on the DNA chains of normal cells, and does not influence the growth of normal cells.

Many physicians are doubtful about the electric field treatment of tumors, which is thought to fail to cure the cancer, but to prolong survival. While the U.S. electric field therapy treatment costs are very expensive ($ 21000 per month). However, in this study, chemotherapy combined with electric field treatment, more than twice as many patients as the control group were still alive after five years of treatment, with a five-year survival rate of 13% and only 5% with chemotherapy alone.

The brain tumor specialist Roger Stupp, university in northwest chicago: "this technique has proven effective", as to how cancer is treated, many physicians currently do not know or believe that electric field therapy can help patients. Roger Stupp bosch led research at the university of zurich hospital, switzerland and reported in 2017 at the washington cancer research association conference.

Disclosure of Invention

The invention aims to provide a device for treating multi-organ tumors based on an electric field.

In order to solve the problems, the technical scheme adopted by the invention is as follows:

the utility model provides a device of multiple organ tumour based on electric field treatment, its key technology lies in, it includes:

the electric field generating device is used for outputting alternating current signals with adjustable voltage waveform, amplitude and frequency;

one end of the lead is connected with the electric field generating device, and the other end of the lead is connected with the field energy electrode patch;

the field energy electrode patch comprises a flexible substrate and a plurality of electrode plate bodies made of insulating capacitor materials, wherein the electrode plate bodies are arranged on the substrate in an array mode, can effectively excite an electric field and avoid generation of conduction current, and are connected with the conducting wires;

a wearable device, a plurality of the field energy electrode patches arranged inside the wearable device; the wearable device comprises one or more of hat, waistcoat, bra and shorts in any combination.

Further, the wearable device is made of elastic fabric, and the wearable device can be wrapped on a human body to enable the field energy electrode patch to be tightly attached to the human body.

Furthermore, the output frequency intensity of the electric field generating device is 0-55Vpp, the electric field intensity is 0-5V/cm, and the modulation frequency is 50-500 KHz.

Furthermore, the maximum output voltage of the electric field generating device is adjustable and ranges from 50 to 120Vpp, the output waveform of the power supply device is sine wave, triangular wave and square wave, the output signals of the power supply device are sequentially output by at least 4 ports to provide voltages in at least 2 directions, and the output time of each port can be adjusted within the range from 0.1 second to 10 seconds.

Further, the air conditioner is provided with a fan,

the field energy electrode patch in the hat is used for treating intracranial tumors, and the frequency of an electric field is 170-230 KHz;

the vest internal field energy electrode patch is used for treatment:

intestinal tumor with electric field frequency of 30-70 KHz;

the electric field frequency of the small cell lung cancer is 170-230 KHz;

the frequency of the electric field of the non-small cell lung cancer is 120-170 KHz;

the field energy electrode patch in the bra is used for treating breast cancer, and the frequency of an electric field is 100-180 KHz;

the pant-in-pant field energy electrode patch is used to treat:

bladder cancer, the frequency of the electric field is 100-180 KHz;

ovarian cancer with an electric field frequency of 170-230 KHz.

Further, the air conditioner is provided with a fan,

the field energy electrode patch in the cap is used for treating intracranial tumors, and the frequency of an electric field is 200 KHz;

the vest internal field energy electrode patch is used for treatment:

intestinal tumor with electric field frequency of 50 KHz;

small cell lung cancer with an electric field frequency of 200 KHz;

non-small cell lung cancer with an electric field frequency of 150 KHz;

the field energy electrode patch in the bra is used for treating breast cancer, and the frequency of an electric field is 120-150 KHz;

the pant-in-pant field energy electrode patch is used to treat:

bladder cancer, the frequency of the electric field is 130-150 KHz;

ovarian cancer with an electric field frequency of 200 KHz.

Further, a thermistor is arranged behind the electrode plate body, when the temperature of the electrode plate body rises to exceed a specific value, the electric field generating device reduces the output or immediately blocks the output, and meanwhile, an alarm prompt is accompanied.

Further, the electrode plate body is made of a ceramic sheet with a high dielectric constant; in biomedical and clinical applications, if an electric field is applied to a human body directly by using a metal electrode, under the action of a conduction current, charged mineral ions in human body cells can migrate, so that the concentration of ions in the cells changes, which is harmful to the human body. In addition, because high conduction current is directly related to the life safety of human bodies, the metal electrodes are used for applying electric fields to carry out medical research and treatment, the voltage cannot be too high, and the applied voltage is limited. Since the pure capacitor is insulated for conducting current and conducted for alternating current electric field, in the experiment of applying alternating voltage in clinic, if the alternating voltage is applied by using the insulated capacitor material with high dielectric constant as an electrode, the side effect of the conducting current on the cell can be avoided. The electric field applied to the body by the capacitive electrodes is localized, and only the localized areas are subjected to the electric field and no conduction current passes through the areas of the body to which the electric field is applied.

Further, the number of the electrode slice bodies arrayed on the field energy electrode patch is as follows: 2, 3, 4, 9, 12, 16 or 32 electrode plates, and a plurality of electrode plate bodies are mutually connected in parallel.

Further, the distance between the adjacent electrode plate bodies is equivalent to the diameter of the electrode plate body.

Further, the wearable device is made of mesh cloth having elasticity.

Adopt the produced beneficial effect of above-mentioned technical scheme to lie in:

the wearable electric field applying device capable of selectively inhibiting the growth of specific cells is formed by combining the electric field generating device with wearable clothes devices such as a hat, a vest, a bra and shorts, a patient can effectively inhibit the growth of various tumor cells by wearing corresponding clothes and communicating field energy electrode patches at corresponding positions and adjusting the electric field intensity and the frequency of pulse signals according to different tumor cells, and the wearable electric field applying device is convenient to use, safe, reliable, suitable for the treatment of tumors of multiple organs and convenient to use for a long time.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic view of the structure of an electric field generating apparatus according to the present invention.

Fig. 2 is a schematic diagram of an electric field therapy device for brain tumors, which is formed by connecting an electric field generating device and a cap with a built-in field energy electrode patch.

Fig. 3 is a schematic view of the inside of the cap of fig. 2 after unfolding.

Fig. 4 is a schematic diagram of a field energy electrode patch.

Fig. 5 is an expanded view of the cap of fig. 2 made of mesh cloth.

Fig. 6 is a schematic diagram of the position of the field energy electrode patch attached to the head of the cap of fig. 2 after the cap is worn on the head.

Fig. 7 is a schematic view of an electric field treatment apparatus for tumor, which is composed of an electric field generator and a vest with a built-in field energy electrode patch.

Figure 8 is a schematic view of the inside of the vest of figure 7 after deployment.

Fig. 9 is a schematic view of the vest of fig. 7 in an expanded configuration using a mesh cloth.

Fig. 10 is a schematic view of an electric field treatment apparatus for breast tumor, which is composed of an electric field generator and a brassiere with a built-in field energy electrode patch.

Fig. 11 is a schematic view of the bra of fig. 10 with field energy electrode patches positioned on the inside of the bra.

Fig. 12 is a schematic view of an electric field treatment apparatus for tumor comprising an electric field generator and shorts having a built-in field energy electrode patch.

Fig. 13 is a schematic view of the panty of fig. 12 shown inside after unfolding.

Fig. 14 is an expanded view of the panty of fig. 12 made of a mesh cloth.

FIG. 15 is a more detailed schematic diagram of the electric field generating apparatus of the present invention.

Figure 16 is an embodiment of the field energy electrode patch of the present invention.

Wherein: 100 electric field generating device, 101 charging battery, 102 waveform signal generator, 103 voltage amplifier, 104 output switching port, 105 output plug port, 106 electrode connecting plug and 107 lead;

200 caps, 201 top cloth pieces, 202 front cloth pieces, 203 rear cloth pieces, 204 left cloth pieces and 205 right cloth pieces;

300-field energy electrode patches, 301 electrode slice bodies, 302 substrates, 303 adjacent electrode slice body spacing, 304 positioning pieces, 305 flexible circuit boards, 306 external leads, 307 sleeves, 308 accommodating grooves and 309 gaps;

400 waistcoats, 401 back cloth pieces, 402 left cloth pieces and 403 right cloth pieces;

500 brassieres, 501 pads;

600 shorts, 601 back panel, 602 left panel, 603 right panel;

001 mesh cloth, 002 head.

Detailed Description

For purposes of clarity and a complete description of the present invention, and the like, in conjunction with the detailed description, it is to be understood that the terms "central," "vertical," "lateral," "up," "down," "front," "back," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for convenience in describing and simplifying the present invention, but do not indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the present invention.

Referring to fig. 1-14, an electric field-based device for treating a multi-organ tumor includes an electric field generating device 100, a lead 107, a field energy electrode patch 300, and a wearable device (200, 400,500, 600). As shown in fig. 1, an electric field generating apparatus 100 includes four components connected to each other: a rechargeable battery 101, a waveform signal generator 102, a voltage amplifier 103 and a voltage output switching port 104. The electric field generating device 100 is provided with 4 output interfaces 105 connected with the voltage output switching interface 104, and the 4 output interfaces 105 sequentially output voltages with the same frequency or different frequencies. Each output jack 105 has two jacks to form a loop with an external circuit.

The electric field generating device 100 is used for outputting alternating current signals with adjustable voltage waveforms, amplitudes and frequencies, the output voltage of the electric field generating device is continuously adjustable and ranges from 0 volt to 65 volts, the output waveforms of the power supply device are sine waves, triangular waves and square waves, the output signals of the power supply device are sequentially output through 4 output interfaces 105, voltages in 4 directions can be provided, and the output time of each port can be adjusted within the range from 0.1 second to 10 seconds.

As shown in fig. 2, one end of the lead 107 is connected to the output interface 105 of the electric field generating device 100 through an electrode connecting plug 106, and the other end is connected to the field energy electrode patch 300; as shown in fig. 4, the field energy electrode patch 300 includes a flexible substrate 302 and a plurality of electrode pad bodies 301 made of insulating capacitor material and arranged on the substrate 302 in an array, wherein the electrode pad bodies 301 can effectively excite an electric field and prevent conduction current from being generated, and the electrode pad bodies 301 are connected to the lead 107. The number of the electrode slice bodies 301 arrayed on the field energy electrode patch 300 is as follows: 2, 3, 4, 9, 12, 16 or 32 electrode plates, and a plurality of electrode plate bodies 301 are connected in parallel. The electrode plate bodies 301 are circular or oval, and the distance 303 between adjacent electrode plate bodies 301 is equal to the diameter of the electrode plate bodies 301. Under the condition that the electrode plate bodies 301 have the same diameter, the coverage area of the field energy electrode patches 300 can be increased by properly increasing the number of the electrode plate bodies 301, so that the distribution range of tumors which can be treated by the whole device is increased, or the positions of the field energy electrode patches 300 are adjusted to adapt to the positions of the tumors.

The electrode plate body 301 is made of a ceramic sheet with a high dielectric constant (the relative dielectric constant is more than 8000). In biomedical and clinical applications, if an electric field is applied to a human body directly by using a metal electrode, under the action of a conduction current, charged mineral ions in human body cells can migrate, so that the concentration of ions in the cells changes, which is harmful to the human body. In addition, because high conduction current is directly related to the life safety of human bodies, the metal electrodes are used for applying electric fields to carry out medical research and treatment, the voltage cannot be too high, and the applied voltage is limited. Since the pure capacitor is insulated for conducting current and conducted for alternating current electric field, in the experiment of applying alternating voltage in clinic, if the alternating voltage is applied by using the insulated capacitor material with high dielectric constant as an electrode, the side effect of the conducting current on the cell can be avoided. The electric field applied to the body by the capacitive electrodes is localized, and only the localized areas are subjected to the electric field and no conduction current passes through the areas of the body to which the electric field is applied.

A thermistor is arranged behind the electrode plate body 301, the electric field generating device 100 further comprises an alarm device, when the temperature of the electrode plate body 301 rises to exceed a specific value, the electric field generating device 100 reduces the output electric field intensity or immediately blocks the output, and meanwhile, an alarm prompt is accompanied; in order to avoid excessive heat generation in the area to be treated, causing discomfort or burning to the patient.

The electric field generating device 100 is further provided with an electrode temperature detection module, the electrode temperature detection module induces the temperature of the electrode plate body through the thermistor, feeds back a corresponding temperature detection signal to a control module of the electric field generating device, and reduces the output of the electric field generating device 100 or immediately blocks the output when the temperature exceeds 41 ℃.

The substrate 302 can be a cloth piece with adhesive sticker on two sides, one side of the substrate is pasted on the inner side of the wearable device, and the other side of the substrate is pasted with the electrode plate body 301; the electrode sheet body 301 is coated with a conductive gel, which may be made of hydrogel, gelatin, agar, etc., and may have salt dissolved therein to improve its electrical conductivity. The exact thickness of the gel is not critical as long as it is thick enough that the gel layer does not dry out during treatment. The outermost side of the field energy electrode patch 300 is also attached with a protective film, and the protective film is removed to expose the conductive gel when in use.

Fig. 16 shows a specific embodiment of a field energy electrode patch 300, wherein a substrate 302 is a medical adhesive tape patch, a plurality of notches 309 are formed in the edge of the substrate 302, and are suitable for wrapping the head or other body parts of a patient, a plurality of positioning pieces 304 are adhered to the substrate 302, the positioning pieces 304 are silica gel positioning pieces for fixing an electrode plate body 301, a plurality of positioning holes are formed in the positioning pieces 304, the electrode plate body 301 is adhered in the positioning holes, the electrode plate body 301 is a ceramic electrode plate and is welded on a flexible circuit board 305, the plurality of electrode plate bodies 301 are connected with an external lead 306 through the flexible circuit board 305, a sleeve 307 is sleeved at the welding position of the flexible circuit board 305 and the external lead 306, and the sleeve 307 is a silica gel sleeve for preventing the welding point from injuring the human. The external lead 306 is connected to the lead 107.

Preferably, in order to ensure that the electrode plate body 301 is in good contact with a human body, the electrode plate body 301 protrudes out of the positioning piece by 0.1-0.2 mm. In order to enable the electrode plate body 301 to be more attached to the head and the like, and to be convenient for a patient to wear, the positioning plate 304 is provided with a containing groove 308 for the flexible circuit board 305 to pass through.

A plurality of the field energy electrode patches 300 are arranged inside the wearable device; the wearable device comprises one or more of hat 200, vest 400, bra 500, shorts 600, and the wearable device can be a blanket, a cape, an overcoat, etc.

The wearable device is made of elastic fabric, and can be wrapped on a human body to enable the field energy electrode patch 300 to be tightly attached to the human body; by adopting the high-elasticity skin-friendly fiber textile, the field energy electrode patch 300 can be tightly attached to a human body (such as a head, a chest and the like) without generating strong constraint feeling to the human body, and the material of the field energy electrode patch is the same as or similar to that of a tight-fitting garment and can be nylon, polyester fiber and the like. Further, the wearable device can be made of mesh cloth 001 with high elasticity, so that the wearable device can avoid increasing burden on the user and causing discomfort in other aspects, such as in summer and other time periods with high temperature, and the wearable device made of the mesh cloth can not cause overheating of the wearing part of the user.

The electric field generating device 100 outputs low-intensity low-frequency electrostatic waves with frequency intensity of 0-55Vpp, electric field intensity of 0-5V/cm and modulation frequency of 50-500 KHz. Furthermore, the maximum output voltage of the electric field generating device is adjustable and ranges from 50 to 120Vpp, the output waveform of the power supply device is sine wave, triangular wave and square wave, the output signals of the power supply device are sequentially output by at least 4 ports to provide voltages in at least 2 directions, and the output time of each port can be adjusted within the range from 0.1 second to 10 seconds. The ability to rupture the membrane and disrupt other cellular structures is enhanced by applying a pulsed alternating electric field at a frequency of about 50KHz to 500KHz, and when this type of electric field is applied to the tissue, the force exerted on the intercellular organelles has a "hammering" effect, whereby the organelles are pulsed (or struck) with an infinite number of forces per second, thereby enhancing the movement of different sized organelles and materials from the two subcellular to the bridge (or neck) portion, thereby increasing the likelihood of rupture of the cell membrane at the bridge site. The forces exerted on intracellular organelles also have an effect on the organelles themselves and may cause the organelles to collapse or break.

As shown in fig. 2, the electric field therapy device for brain tumors is formed by connecting an electric field generating device 100 with a cap 200 with a built-in field energy electrode patch; FIG. 3 is a schematic view of the inside of the cap 200 shown in FIG. 2 after unfolding, which includes a top cloth 201 at the middle, a front cloth 202, a rear cloth 203, a left cloth 204 and a right cloth 205 arranged around the top cloth 201; the top cloth piece 201 is arranged on the top cloth piece 201, the front cloth piece 202, the rear cloth piece 203, the left cloth piece 204 and the right cloth piece 205, and the field energy electrode patches 300 are arranged on the top cloth piece 201, the front cloth piece 202, the rear cloth piece 203, the left cloth piece 204 and the right cloth piece 205, and each field energy electrode patch 300 is connected with the electric field generating device 100 through a lead. When in use, the corresponding electrode connecting plug 106 can be plugged in and pulled out to enable the field energy electrode patches 300 at different positions to conduct an electric field. As shown in FIG. 5, the cap 200 of FIG. 2 is shown in an expanded view and made of a mesh cloth 001. The mesh cloth 001 is preferably made of a material having elasticity.

It should be understood that the left panel 204 and the right panel 205 are shown from the perspective of the viewer, with the left panel 204 positioned to the right of the user and the right panel 205 positioned to the left of the user at the user's perspective.

As shown in fig. 6, which is a schematic diagram of the position where the field energy electrode patch 300 is attached to the head 002 after the cap 200 is worn on the head 002, the field energy electrode patch 300 at the corresponding position can conduct the electric field according to the difference of the brain tumor-repairing positions.

The field energy electrode patch in the cap 200 is used for treating intracranial tumors, and the frequency of an electric field is 170-230 KHz; preferably, the frequency of the electric field is 200 KHz.

As shown in fig. 7, the electric field therapy apparatus for treating tumor is composed of an electric field generating device 100 and a vest 400 having a field energy electrode patch 300 built therein, and as shown in fig. 8, the vest 200 shown in fig. 7 is shown as an inside schematic view after being unfolded, and includes a back cloth 401, and a left cloth 402 and a right cloth 403 respectively provided on both sides of the back cloth 401. The upper part and the lower part of the back cloth piece 401 are respectively provided with a field energy electrode patch 300, the field energy electrode patch 300 positioned at the upper part of the back cloth piece 401 corresponds to the part of the human body vest, and the field energy electrode patch 300 positioned at the lower part of the back cloth piece 401 corresponds to the human body waist organ. The left cloth piece 402 and the right cloth piece 403 are also provided with field energy electrode patches 300; as shown in fig. 8 and 9, the field electrode patch 300 is disposed at a position where the left cloth 402 and the right cloth 403 are connected to the back cloth 401, where the field electrode patch 300 corresponds to both side portions of the human body's trunk. If the field energy electrode patch 300 is moved outward, it will correspond to the chest and lung when it is up, and it will correspond to the abdominal organs, such as intestine, stomach, liver, etc. Fig. 9 is a schematic view showing the waistcoat 400 of fig. 7, which is made of a mesh cloth 001 and can be conveniently used in summer.

When the field energy electrode patch 300 in the vest 400 is used for treating intestinal tumors, the frequency of an electric field is 30-70KHz, preferably 50 KHz; when used for treating the small cell lung cancer, the electric field frequency is 170-230KHz, preferably 200 KHz; when used for treating the non-small cell lung cancer, the electric field frequency is 120-170KHz, preferably 150 KHz; can be used for the treatment of diseases.

Fig. 10 is a schematic view of an electric field treatment device for breast tumor, which is formed by connecting an electric field generator 100 and a bra 500 with a built-in field energy electrode patch 300, fig. 11 is a schematic view of the field energy electrode patch 300 arranged on the inner side of the bra in fig. 10, the field energy electrode patch 300 is arranged on the inner side of a spherical-crown-shaped pad 501, and an electrode plate body 301 is arranged around the breast, so that an electric field can be effectively applied to tumor cells in the breast.

The field energy electrode patch 300 in the bra is used for treating breast cancer, and the electric field frequency is 100-180KHz, preferably 120-150 KHz.

Fig. 12 is a schematic view of the tumor electric-field treatment apparatus in which the electric-field generating device 100 is connected to a pants 600 having a built-in field-energy electrode patch 300, fig. 13 is a schematic view of the inside of the pants 600 shown in fig. 12 after being unfolded, and fig. 14 is a schematic view of the shorts 600 shown in fig. 12 being unfolded using a mesh fabric 001. As shown in fig. 13, the shorts 600 include a rear panel 601 and left and

right panels

602 and 603 respectively disposed at left and right sides of the rear panel 601, and the field energy electrode patch 300 is disposed at a suitable position of the rear panel 601, the left panel 602, and the right panel 603, the field energy electrode patch 300 corresponding to the bladder, ovary, etc. of the human body.

As shown in fig. 13, the field energy electrode patch 300 is disposed at the connection portion of the left cloth piece 602 and the right cloth piece 603 with the rear cloth piece 601, and the field energy electrode patch 300 is positioned at both sides of the waist crotch of the human body after wearing; as shown in fig. 14, the shorts 600 are of a high waist type, and the field energy electrode patches 300 are respectively positioned at upper positions on the left and

right side panels

602 and 603, and correspond to both sides of the lower abdomen of a human body after wearing. If the field energy electrode patch 300 is disposed at a position on the left and right upper sides of the rear fabric 601, the worn field energy electrode patch 300 corresponds to the back of the waist side of the human body.

When the field energy electrode patch in the shorts 600 is used for treating bladder cancer, the frequency of the electric field is 100-180KHz, preferably 130-150 KHz; for treating ovarian cancer, the frequency of the electric field is 170-230KHz, and the preferred frequency of the electric field is 200 KHz.

As shown in fig. 15, which is a more detailed schematic diagram of the electric field generating device 100 of the present invention, the electric field generating device 100 includes a power management module, a rechargeable battery, a control host module, a DC-DC module, a signal generating module, a power amplifying module, a current detecting module, and a temperature sensing module.

Wherein:

1. a power management module:

1) converting commercial power input through an adapter into a DC power supply to be respectively supplied to the control host module, the DC-DC module and the rechargeable battery;

2) and respectively supplying the DC power output by the rechargeable battery to the control host module and the DC-DC module.

2. A DC-DC module: and converting the DC power output by the power management module into a DC power supply to be supplied to the power amplification module.

3. Charging a battery:

1) when the commercial power is switched on, the 1DC power output by the power management module is stored;

2) when the commercial power is not connected, outputting a DC power supply to the power management module;

3) the voltage feedback signal is transmitted to the control host module, and the electric quantity condition of the rechargeable battery is monitored in real time;

4) the battery protection function is provided, battery damage caused by overshoot, overdischarge and the like is prevented, and the service life of the battery is prolonged.

Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims

1. An apparatus for electric field-based treatment of multiple organ tumors, comprising:

the field energy electrode patch comprises a flexible substrate and a plurality of electrode plate bodies made of insulating capacitor materials, wherein the electrode plate bodies are arranged on the substrate in an array mode and are used for effectively exciting an electric field and avoiding generation of conduction current, and the electrode plate bodies are connected with the conducting wires;

2. The device of claim 1, wherein said device comprises: the wearable device is made of elastic fabric, and can be wrapped on a human body to enable the field energy electrode patch to be tightly attached to the human body.

3. The device of claim 1, wherein said device comprises: the output amplitude of the electric field generating device is 0-120vpp, the electric field intensity is 0-5V/cm, and the modulation frequency is 50-500 KHz.

4. The device of claim 3, wherein said device comprises: the maximum output voltage of the electric field generating device is adjustable and ranges from 50 to 120Vpp, the output waveform of the power supply device is sine wave, triangular wave and square wave, the output signals of the power supply device are sequentially output through at least 4 ports to provide voltages in at least 2 directions, and the output time of each port can be adjusted within the range from 0.1 second to 10 seconds.

5. The device of claim 3, wherein said device comprises:

the vest internal field energy electrode patch is used for treatment:

intestinal tumor with electric field frequency of 30-70 KHz;

the electric field frequency of the small cell lung cancer is 170-230 KHz;

the pant-in-pant field energy electrode patch is used to treat:

bladder cancer, the frequency of the electric field is 100-180 KHz;

ovarian cancer with an electric field frequency of 170-230 KHz.

6. The device of claim 1, wherein said device comprises: the rear surface of the electrode plate body is provided with a thermistor, the temperature of the electrode plate body is increased to exceed a specific value, the electric field generating device reduces the output or immediately blocks the output, and meanwhile, an alarm prompt is accompanied.

7. The device of claim 1, wherein said device comprises: the electrode plate body is made of a ceramic chip with high dielectric constant.

8. The device of claim 1, wherein said device comprises: the number of the electrode slice bodies of the array on the field energy electrode patch is as follows: 2, 3, 4, 9, 12, 16 or 32 electrode plates, and a plurality of electrode plate bodies are mutually connected in parallel.

9. The device of claim 1, wherein said device comprises: the distance between the adjacent electrode plate bodies is equivalent to the diameter of the electrode plate body.

10. The device of claim 1, wherein said device comprises: the wearable device is made of mesh cloth with elasticity.