CN112933407A - Electrode structure, electrode patch and cell division suppression device - Google Patents
Electrode structure, electrode patch and cell division suppression device Download PDFInfo
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- 230000032823 cell division Effects 0.000 title claims abstract description 37
- 230000001629 suppression Effects 0.000 title description 4
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- 230000005764 inhibitory process Effects 0.000 abstract description 21
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
Abstract
The embodiment of the application provides an electrode structure, an electrode patch and a cell division inhibition device. The electrode structure includes: at least one stage of electrode main body in the at least two stages of electrode main bodies is used for being electrically connected with a power supply; and one end of any one electric connection structure is connected with one stage of electrode main body in the adjacent two stages of electrode main bodies, and the other end of any one electric connection structure is connected with the other stage of electrode main body in the adjacent two stages of electrode main bodies. The embodiment of the application adopts a multi-stage electrode structure of at least two stages of electrode main bodies, which is beneficial to increasing the output electric field area and improving the inhibition efficiency of cell division; the adjacent two-stage electrode main bodies are directly and electrically connected through the electric connection structure, so that the current distribution in each electrode is more balanced, the electric field intensity output by each electrode is more balanced, the somatosensory comfort degree of a patient is improved, and the inhibition effect of the electric field on cell division is improved.
Description
Technical Field
The application relates to the technical field of medical equipment, in particular to an electrode structure, an electrode patch and a cell division inhibition device.
Background
The electric field therapy is to use an electric field to destroy mitosis to prevent cancer cells from finishing rapid division, attach an electrode patch to a focus area, or influence tubulin to aggregate into clusters through the metaphase of the electric field to prevent the formation of a spindle body in diseased cells, so that chromosomes cannot be normally separated; or at the end of the division of the diseased cell, the electric field pushes the charge towards the neck of the dividing cell, destroying the diseased cell structure. Both mechanisms of action lead to the end result of inhibiting normal division of diseased cells.
The electrode patch is an important execution structure of the electric field therapy, and the self structure of the electrode patch directly influences the performance of an output electric field. However, the existing electrode patch has the defects of limited electric field area, uneven electric field intensity distribution, high energy consumption and the like.
Disclosure of Invention
The utility model provides an electrode structure, electrode paster and cell division suppression device to the shortcoming of current mode for there is the electric field area of electrode paster output to solve prior art, or electric field intensity distribution is inhomogeneous, or technical problem such as the energy consumption is higher.
In a first aspect, an embodiment of the present application provides an electrode structure, including:
at least one stage of electrode main body in the at least two stages of electrode main bodies is used for being electrically connected with a power supply;
and one end of any one electric connection structure is connected with one stage of electrode main body in the adjacent two stages of electrode main bodies, and the other end of any one electric connection structure is connected with the other stage of electrode main body in the adjacent two stages of electrode main bodies.
Optionally, the electrode body is used to generate an electric field that inhibits cell division or kills cells.
Optionally, in the two adjacent electrode bodies, the electrode body of the previous stage is configured with at least one electrode body of the next stage, and each electrode body of the next stage surrounds the electrode body of the previous stage.
Optionally, the electrode body comprises at least one of the following features:
the ratio of the sizes of the upper-stage electrode main body and the lower-stage electrode main body is not less than 1:1 and not more than 4: 1;
the ratio of the distance between the upper-stage electrode main body and the lower-stage electrode main body to the maximum outer diameter of the upper-stage electrode main body is not less than 1:2 and not more than 4: 1;
the ratio of the number of the electrode bodies of the upper stage to the number of the electrode bodies of the lower stage is not less than 1:10 and not more than 1: 1.
Optionally, the electrode structure further comprises: at least one barbed structure; one end of any prickle structure is connected with an electrode main body.
Optionally, the electrode body comprises at least one of a polygonal electrode body, an electrode body with a curved outer contour line, and an irregularly shaped electrode body.
Optionally, at least one of the corners of the polygonal electrode main body is connected to one end of the electrical connection structure.
Optionally, the electrode structure further comprises: at least one barbed structure; among the corners of the polygonal electrode main body which are not connected with the electric connection structure, at least one corner is connected with one end of the corresponding bur structure.
Optionally, the polygonal electrode body is a regular polygonal electrode body.
In a second aspect, embodiments of the present application provide an electrode patch, including: the electrode structure as provided in any one of the first to third aspects.
Optionally, the electrode patch further comprises an insulating layer and a skin-friendly layer which are stacked; the electrode structure is positioned between the insulating layer and the skin-friendly layer, and an electrode main body of the electrode structure is electrically connected with a power supply; the side of the skin-friendly layer far away from the insulating layer is used for being attached to the surface of the skin.
Optionally, a containing groove is formed in one side, close to the skin-friendly layer, of the insulating layer; the electrode structure is embedded in the containing groove.
In a third aspect, embodiments of the present application provide a cell division inhibiting device, comprising: a power source, and any one of the electrode patches as provided in the second aspect;
the electrode main body of the electrode structure in the electrode patch is electrically connected with a power supply.
Optionally, the power supply is an alternating current power supply; or the power supply is a pulse power supply.
The beneficial technical effects brought by the technical scheme provided by the embodiment of the application at least comprise:
1. the multi-stage electrode structure with at least two stages of electrode bodies is favorable for increasing the output electric field area, and further the inhibition efficiency of cell division is improved.
2. Can be connected through electric connection structure direct electricity between the adjacent two-stage electrode main part, be favorable to making the current distribution in each electrode more balanced, do benefit to the electric field intensity of each electrode output more balanced, can greatly reduce the amazing or local heat effect of electric current on the one hand, improve the body of disease and feel comfort level, on the other hand can improve the inhibitory effect of electric field to cell division, can reduce energy loss on the one hand again, improve energy utilization efficiency.
Additional aspects and advantages of the present application will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the present application.
Drawings
The foregoing and/or additional aspects and advantages of the present application will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:
fig. 1 is a schematic structural diagram of a first embodiment of an electrode structure according to an embodiment of the present disclosure;
fig. 2 is a schematic structural diagram of a second embodiment of an electrode structure according to an embodiment of the present disclosure;
fig. 3 is a schematic structural diagram of a third embodiment of an electrode structure according to an embodiment of the present disclosure;
fig. 4 is a schematic structural diagram of an electrode patch according to an embodiment of the present disclosure;
FIG. 5 is a schematic view of the structure of the plane A-A in FIG. 4;
fig. 6 is a schematic diagram of a cell division suppressing apparatus according to an embodiment of the present disclosure.
In the figure:
10-an electrode structure;
11-a first stage electrode body; 12-a second stage electrode body; 13-a third stage electrode body; 14-a fourth stage electrode body; 15-an electrical connection structure; 16-barbed structure;
20-electrode patch; 21-an insulating layer; 21 a-a receiving groove; 22-skin-friendly layer; 23-a wire;
30-a cell division inhibiting device; 31-power supply.
Detailed Description
Reference will now be made in detail to the present application, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar parts or parts having the same or similar functions throughout. In addition, if a detailed description of the known art is not necessary for illustrating the features of the present application, it is omitted. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present application and are not to be construed as limiting the present application.
It will be understood by those within the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
As used herein, the singular forms "a", "an", "the" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof. It is to be understood that the term "and/or" as used herein is intended to include all or any and all combinations of one or more of the associated listed items.
The inventors of the present application have conducted studies to find that, in the existing electrode patches, only one electrode is generally configured for each electrode patch, which results in a very limited electric field area output by the electrode patch, and severely limits the inhibition efficiency of cell division. In some electrode patches with a plurality of electrodes, each electrode is independently arranged, that is, each electrode has an independent wire to supply power, and there is no electrical connection between the electrodes, so that the current distribution in each electrode is uneven, and the electric field intensity output by each electrode is uneven. The unbalanced current distribution can cause certain current stimulation or local heat effect, so that the patients feel uncomfortable; the unbalanced distribution of the electric field will affect the inhibition effect of the electric field on cell division, resulting in incomplete inhibition of cell division. In addition, the independent arrangement of the electrodes also causes the increase of energy consumption in the process of shunting or voltage division.
The application provides an electrode structure, electrode paster and cell division suppression device, aims at solving prior art technical problem as above.
The following describes the technical solutions of the present application and how to solve the above technical problems with specific embodiments.
It should be noted that, in order to facilitate the reader to understand the technical solutions proposed in the present application more easily, the electrode structures shown in the following embodiments are all described by taking a four-stage structure (including the first-stage electrode main body 11, the second-stage electrode main body 12, the third-stage electrode main body 13, and the fourth-stage electrode main body 14) as an example, but the technical solutions proposed in the present application are not necessarily applied to the case of only a four-stage structure, and are of course applied to electrode structures having two, three, five, six, and more stages.
The embodiment of the present application provides an electrode structure 10, and a schematic structural diagram of the electrode structure 10 is shown in fig. 1, including but not limited to: at least two electrode bodies, and at least one electrical connection structure 15.
At least one of the at least two stages of electrode bodies is adapted to be electrically connected to a power source 31.
One end of any one of the electrical connection structures 15 is connected to one of the two adjacent stages of electrode bodies, and the other end of any one of the electrical connection structures 15 is connected to the other of the two adjacent stages of electrode bodies.
In fig. 1, n1, n2, and n3 may be selected as follows: 0,1,2,3 … …, and the like.
Optionally, the electrode body is used to generate an electric field that inhibits cell division or kills cells.
In the present embodiment, the multi-stage electrode structure 10 using at least two stages of electrode bodies is advantageous for increasing the output electric field area, thereby improving the cell division inhibition efficiency.
Moreover, the adjacent two-stage electrode main bodies can be directly and electrically connected through the electric connection structure 15, so that the current distribution in each electrode is more balanced, the electric field intensity output by each electrode is more balanced, on one hand, the current stimulation or the local heat effect can be greatly reduced, the somatosensory comfort level of a patient is improved, on the other hand, the inhibition effect of an electric field on cell division can be improved, on the other hand, the energy loss can be reduced, and the energy utilization efficiency is improved.
For example, as shown in fig. 2 or 3, the electrode structure 10 may be a quaternary structure including a first-stage electrode body 11, a second-stage electrode body 12, a third-stage electrode body 13, and a fourth-stage electrode body 14. The first electrode main body 11 and the second electrode main body 12 are directly and electrically connected through an electrical connection structure 15, the second electrode main body 12 and the third electrode main body 13 are directly and electrically connected through an electrical connection structure 15, and the third electrode main body 13 and the fourth electrode main body 14 are directly and electrically connected through an electrical connection structure 15.
Alternatively, the electrode bodies and the electrical connection structures 15 may be made of the same conductive material.
In some possible embodiments, in the two adjacent electrode bodies, the upper electrode body is provided with at least one lower electrode body, and each lower electrode body surrounds the upper electrode body.
In this embodiment, a layout structure in which the next-stage electrode main body surrounds the previous-stage electrode main body is adopted, which is beneficial to balancing current distribution among the next-stage electrode main bodies. And, every next stage electrode main part is connected with the last stage electrode main part through corresponding electric connection structure 15, can be favorable to making the current distribution in each electrode more balanced, and the electric field intensity that does benefit to each electrode output is more balanced.
For example, as shown in fig. 2 or fig. 3, a plurality of second-stage electrode bodies 12 corresponding to the surrounding layout of one first-stage electrode body 11, a plurality of third-stage electrode bodies 13 corresponding to the surrounding layout of one second-stage electrode body 12, and a plurality of fourth-stage electrode bodies 14 corresponding to the surrounding layout of one third-stage electrode body 13.
It can be understood that the larger the number of the next-stage electrode bodies in the two adjacent-stage electrode bodies, the more beneficial the output electric field area is increased, and the inhibition efficiency of cell division is improved.
Optionally, the distances between each next-stage electrode body and the previous-stage electrode body are equal.
Optionally, the distances between each next-stage electrode main body and the previous-stage electrode main body are not equal. For example: the connecting line of the central points of the next-stage electrode main bodies is a closed ring formed by wavy lines.
Optionally, the next-stage electrode main body and the previous-stage electrode main body are each in a fractal structure, that is, each stage of electrode main body can adopt a fractal structure, and each next-stage electrode main body is in a shape obtained by reducing the previous-stage electrode main body according to a certain proportion. Of course, in the case where the number of stages of the electrode main bodies is small or the distance between the electrode main bodies of the respective stages is sufficient, each electrode main body of the next stage may be in a shape obtained by enlarging the electrode main body of the previous stage in a certain ratio. The fractal structure is adopted, so that the current distribution in each electrode is more balanced, and the electric field intensity output by each electrode is more balanced.
For example, as shown in fig. 3, the second stage electrode body 12 is formed by reducing the first stage electrode body 11 by a predetermined ratio, the third stage electrode body 13 is formed by reducing the second stage electrode body 12 by a predetermined ratio, and the fourth stage electrode body 14 is formed by reducing the third stage electrode body 13 by a predetermined ratio.
Optionally, each next-stage electrode body is rotationally symmetric with respect to the corresponding previous-stage electrode body. The rotationally symmetrical layout structure is adopted, the electric field intensity output by the whole electrode structure 10 is more balanced, the current stimulation or the local heat effect can be greatly reduced, the somatosensory comfort level of a patient is improved, the inhibition effect of an electric field on cell division can be improved, the energy loss can be reduced, and the energy utilization efficiency is improved.
For example, as shown in fig. 3, each of the second-stage electrode bodies 12 surrounding one of the first-stage electrode bodies 11 is rotationally symmetric with respect to the first-stage electrode body 11; third electrode bodies 13 surrounding a second electrode body 12, each third electrode body being rotationally symmetric with respect to the second electrode body 12; the fourth electrode bodies 14, which surround one third electrode body 13, are rotationally symmetrical with respect to the third electrode body 13.
In any of the above embodiments, the electrode body may include, but is not limited to, at least one of the following features:
optionally, a ratio of the sizes of the upper-stage electrode body and the lower-stage electrode body is not less than 1:1 and not more than 3: 1.
Optionally, the ratio of the distance between the electrode main body of the previous stage and the electrode main body of the next stage to the maximum outer diameter of the electrode main body of the previous stage is not less than 1:2 and not more than 3: 1.
Optionally, the ratio of the number of the upper-stage electrode bodies to the lower-stage electrode bodies is not less than 1:10 and not more than 1: 1.
The inventors of the present application consider that the region of the electric field output by the electrode structure 10 has a certain relationship with the point on the electrode structure 10 at which the electric field can be output. To this end, the present application provides one possible implementation of the electrode structure 10 as follows:
as shown in fig. 2 or fig. 3, the electrode structure 10 of the embodiment of the present application further includes, but is not limited to: at least one barbed structure 16. One end of any of the barbed structures 16 is connected to one of the electrode bodies. Wherein, the barbed structure can be similar to the small barbed structure on the stem leaf and the fruit shell of the plant, is slender and has a certain tip.
In this embodiment, under the power-on condition, the tip of each of the barbed structures 16 may facilitate the formation of charge accumulation, thereby forming a sub-electric field. The sub-electric field can be used to form a supplementary electric field of the main electric field formed at each stage of the electrode main body, that is, the electric field area of the whole output of the electrode structure 10 can be perfected, thereby improving the inhibition efficiency of cell division.
It can be understood that the barbed structures 16 may be disposed according to a position between each next-stage electrode main body and the corresponding previous-stage electrode main body, that is, a weaker electric field region in the main electric field formed by each stage of electrode main body, so that the sub electric field generated by the barbed structures 16 may play a role in supplementing the electric field strength.
In addition, the sub electric field at the tip of the prickle structure 16 and the main electric field at the electrode main body can form a composite electric field, which is beneficial to improving the inhibition effect of cell division.
Alternatively, the barbed structures 16 may be formed from the same conductive material as the electrode bodies of the respective stages.
Alternatively, the barbed structures 16 may be made of the same conductive material as the electrical connection structures 15.
Alternatively, the barbed structures 16 may be the same or similar in size or shape as the electrical connection structures 15. For example, the barbed structure 16 may be straight, curved, wavy, or lightning-like, among others.
The inventor of the present application considers that the electrode shape of the electrode patch 20 is mostly circular or convex, and only one electric field can be formed at each electrode, which prevents the increase of the electric field area or the individual requirement. To this end, the present application provides one possible implementation of the electrode structure 10 as follows:
the electrode body of the embodiments of the present application includes, but is not limited to, at least one of a polygonal electrode body, an electrode body having a curved outer contour line, and an irregularly shaped electrode body.
Alternatively, the shape of the polygonal electrode body may be triangular, rectangular, pentagonal, hexagonal, etc., and so on. The electrode body with the curved outer contour line can be a closed figure with the contour line being an arc line or a wavy line, and can also be a circle or an ellipse.
In some possible embodiments, when the electrode main body adopts a polygonal electrode main body structure, the corners of the polygonal electrode main body can also form a certain pointed structure, so that under the power-on condition, the corners of the polygonal electrode main body can also be beneficial to forming charge accumulation, and further forming a sub-electric field. The sub-electric field can also be used to form a supplementary electric field of the main electric field formed at each stage of the electrode main body, that is, the electric field area of the whole output of the electrode structure 10 can be perfected, thereby improving the inhibition efficiency of cell division.
In addition, the sub-electric fields at the corners of the polygonal electrode main body and the main electric field at the electrode main body can form a composite electric field, and the inhibition effect of cell division is favorably improved.
In some possible embodiments, at least one of the corners of the polygonal electrode main body is connected to one end of the electrical connection structure 15.
In this embodiment, one end of the electrical connection structure 15 is connected to the corners of the polygonal electrode main body, so that the characteristic that charges are easily gathered to the corners of the polygonal electrode main body can be fully utilized, the conductivity between two adjacent stages of electrode main bodies can be improved, the energy loss can be reduced, and the energy utilization efficiency can be improved.
It can be understood that, the corners of the polygonal electrode main body not connected to the electrical connection structure 15 can still form a certain sub-electric field, and the supplementary electric field of the main electric field formed at each stage of electrode main body improves the electric field area of the whole output of the electrode structure 10, thereby improving the inhibition efficiency of cell division.
In some possible embodiments, the electrode structure 10 further includes, but is not limited to: at least one barbed structure 16. Among the corners of the polygonal electrode main body, which are not connected to the electrical connection structure 15, at least one corner is connected to one end of the corresponding barbed structure 16.
In this embodiment, one end of the barbed structure 16 is connected to the corner of the polygonal electrode main body, so that the characteristic that charges are easily accumulated to the corner of the polygonal electrode main body can be fully utilized, the charge accumulation effect of the sharp end of the barbed structure 16 is improved, and the sub-electric field generated at the sharp end of the barbed structure 16 can be strengthened.
It can be understood that, in the polygonal electrode main body, the corners which are not connected with the electrical connection structure 15 and the bur structure 16 can still form a certain sub-electric field, and a supplementary electric field of the main electric field formed at each stage of electrode main body improves the electric field area output by the whole electrode structure 10, thereby improving the inhibition efficiency of cell division.
Optionally, the polygonal electrode body is a regular polygonal electrode body. The charge accumulation degree of each corner is balanced, namely the intensity of the sub-electric field formed at the corner of the polygonal electrode main body is more balanced.
Based on the same inventive concept, the present application provides an electrode patch 20, as shown in fig. 4, the electrode patch 20 includes but is not limited to: any of the electrode structures 10 as provided in the previous embodiments.
In the present embodiment, since the electrode patch 20 adopts any one of the electrode structures 10 provided in the foregoing embodiments, the principle and technical effects thereof refer to the foregoing embodiments, and are not described herein again.
Alternatively, the electrode patches 20 may be used in pairs. For example, in use, any pair of electrode patches 20 is attached to the skin on both sides of the lesion tissue such that the electrode patches 20 are opposite or substantially opposite, and the electric field generated by the electrode structure 10 in each pair of electrode patches 20 acts together on the lesion tissue cells to inhibit normal division of the lesion cells.
In some possible embodiments, the electrode patch 20 further includes an insulating layer 21 and a skin-friendly layer 22 that are disposed in a stack.
The electrode structure 10 is located between the insulating layer 21 and the skin-friendly layer 22, and an electrode main body of the electrode structure 10 is used for being electrically connected with the power supply 31.
The side of the skin-friendly layer 22 away from the insulating layer 21 is used for attachment to the skin surface.
In this embodiment, the skin-friendly layer 22 may facilitate the electrode patch 20 to be attached to the skin surface corresponding to the focal tissue. The insulating layer 21 can prevent unnecessary electric leakage when the electrode patch 20 is operated, improve safety during operation, and reduce energy consumption.
Alternatively, the skin-friendly layer 22 may employ a silicone material.
Optionally, as shown in fig. 5, a receiving groove 21a is formed on a side of the insulating layer 21 close to the skin-friendly layer 22, and the electrode structure 10 is embedded in the receiving groove 21 a. This facilitates the complete attachment of the insulating layer 21 to the skin-friendly layer 22, and improves the structural stability of the electrode patch 20.
Optionally, as shown in fig. 4, the electrode patch 20 further includes a lead 23. One end of the lead 23 extends into the receiving groove 21a from between the insulating layer 21 and the skin-friendly layer 22, and is connected to any primary electrode main body (e.g., the primary electrode main body 11) of the electrode structure 10, and the other end of the lead 23 is used for electrically connecting to a power supply, so as to supply power to the electrode structure 10 of the electrode patch 20.
Based on the same inventive concept, the present application provides a cell-division inhibiting device 30, as shown in fig. 6, wherein the cell-division inhibiting device 30 includes but is not limited to: a power source 31, and any one of the electrode patches 20 as provided in the previous embodiments.
The electrode body of the electrode structure 10 in the electrode patch 20 is electrically connected to a power source 31.
In this embodiment, the power supply 31 may provide electrical energy to the electrode structure 10 in the electrode patch 20, such that the electrode structure 10 is capable of generating the required electric field.
In the present embodiment, since the cell-division suppressing device 30 employs any one of the electrode patches 20 provided in the foregoing embodiments, the principle and technical effects thereof are please refer to the foregoing embodiments, and are not described herein again.
Optionally, the power source 31 is an ac power source 31. The alternating current supplied by the alternating current source 31 enables the electrode structure 10 in the electrode patch 20 to generate the required alternating electric field.
Optionally, the power supply 31 is a pulsed power supply 31. The pulsed current provided by the pulsed power source 31 enables the electrode structure 10 in the electrode patch 20 to generate the desired pulsed electric field.
By applying the embodiment of the application, at least the following beneficial effects can be realized:
1. the multi-stage electrode structure 10 using at least two stages of electrode bodies is advantageous for increasing the output electric field area, thereby improving the inhibition efficiency of cell division.
2. Can be through electric connection structure 15 direct electricity between the adjacent two-stage electrode main part, be favorable to making the current distribution in each electrode more balanced, do benefit to the electric field intensity of each electrode output more balanced, can greatly reduce electric current stimulation or local heat effect on the one hand, improve the body of disease and feel comfort level, on the other hand can improve the inhibitory effect of electric field to cell division, can reduce energy loss on the one hand again, improve energy utilization efficiency.
3. The layout structure that the next-stage electrode main body surrounds the upper-stage electrode main body is adopted, so that the current distribution among the next-stage electrode main bodies is balanced. And, every next stage electrode main part is connected with the last stage electrode main part through corresponding electric connection structure 15, can be favorable to making the current distribution in each electrode more balanced, and the electric field intensity that does benefit to each electrode output is more balanced.
4. The electrode main bodies at all levels can adopt fractal structures, so that the current distribution in each electrode is more balanced, and the electric field intensity output by each electrode is more balanced.
5. Each next-stage electrode main body is rotationally symmetrical about the corresponding previous-stage electrode main body, so that the electric field intensity output by the whole electrode structure 10 is more balanced, the current stimulation or the local heat effect can be greatly reduced, the somatosensory comfort degree of a patient is improved, the inhibition effect of an electric field on cell division can be improved, the energy loss can be reduced, and the energy utilization efficiency is improved.
6. The tips of the barbed structures 16 may facilitate the formation of charge concentrations and thus sub-electric fields. The sub-electric field can be used to form a supplementary electric field of the main electric field formed at each stage of the electrode main body, that is, the electric field area of the whole output of the electrode structure 10 can be perfected, thereby improving the inhibition efficiency of cell division.
7. When the electrode main body adopts a polygonal electrode main body structure, the corners of the polygonal electrode main body can also form a certain tip structure, so that under the electrifying condition, the corners of the polygonal electrode main body can also be favorable for forming charge aggregation, and further forming a sub-electric field. The sub-electric field can also be used to form a supplementary electric field of the main electric field formed at each stage of the electrode main body, that is, the electric field area of the whole output of the electrode structure 10 can be perfected, thereby improving the inhibition efficiency of cell division.
8. One end of the electric connection structure 15 is connected with the corners of the polygonal electrode main body, so that the characteristic that charges are easily gathered to the corners of the polygonal electrode main body can be fully utilized, the electric conduction capability between the adjacent two stages of electrode main bodies is improved, the energy loss can be reduced, and the energy utilization efficiency is improved.
9. One end of the bur structure 16 is connected with the corners of the polygonal electrode main body, so that the characteristic that charges are easily gathered to the corners of the polygonal electrode main body can be fully utilized, the charge gathering effect of the tip of the bur structure 16 is improved, and the sub-electric field generated at the tip of the bur structure 16 is favorably strengthened.
10. The polygonal electrode main body is a regular polygonal electrode main body, so that the charge accumulation degree of each corner is balanced, namely the intensity of sub-electric fields formed at the corners of the polygonal electrode main body is more balanced.
It will be understood by those skilled in the art that in the description of the present application, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used for convenience of description and simplicity of description only, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be considered as limiting.
The terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless otherwise specified.
In the description of the present application, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present application can be understood in a specific case by those of ordinary skill in the art.
In the description herein, particular features, structures, materials, or characteristics may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing is only a partial embodiment of the present application, and it should be noted that, for those skilled in the art, several modifications and decorations can be made without departing from the principle of the present application, and these modifications and decorations should also be regarded as the protection scope of the present application.
Claims (15)
1. An electrode structure, comprising:
the electrode body of at least one stage in the electrode bodies of at least two stages is used for being electrically connected with a power supply;
and one end of any one electric connection structure is connected with one stage of the electrode main bodies in the two adjacent stages of the electrode main bodies, and the other end of any one electric connection structure is connected with the other stage of the electrode main bodies in the two adjacent stages of the electrode main bodies.
2. The electrode structure of claim 1, wherein the electrode body is configured to generate an electric field that inhibits cell division or kills cells.
3. The electrode structure according to claim 1, wherein at least one next-stage electrode body is provided to the electrode body of the upper stage among the adjacent two stages of electrode bodies, and each next-stage electrode body surrounds the electrode body of the upper stage.
4. The electrode structure of claim 3, wherein the electrode body of the next stage and the electrode body of the previous stage are fractal structures;
and/or each next-stage electrode body is rotationally symmetrical with respect to the corresponding previous-stage electrode body.
5. The electrode structure of claim 3, wherein the electrode body comprises at least one of the following features:
the ratio of the sizes of the electrode main body of the upper stage to the electrode main body of the lower stage is not less than 1:1 and not more than 4: 1;
the ratio of the distance between the electrode main body of the previous stage and the electrode main body of the next stage to the maximum outer diameter of the electrode main body of the previous stage is not less than 1:2 and not more than 4: 1;
the ratio of the number of the electrode bodies of the upper stage to the number of the electrode bodies of the lower stage is not less than 1:10 and not more than 1: 1.
6. The electrode structure according to any one of claims 1 to 5, further comprising: at least one barbed structure;
one end of any prickle structure is connected with one electrode main body.
7. The electrode structure according to any one of claims 1 to 5, wherein the electrode body comprises at least one of a polygonal electrode body, an electrode body whose outer contour line is a curved line, and an irregularly shaped electrode body.
8. The electrode structure of claim 7, wherein at least one of the corners of the polygonal electrode body is connected to one end of the electrical connection structure.
9. The electrode structure of claim 8, further comprising: at least one barbed structure;
in the corners of the polygonal electrode main body which are not connected with the electric connection structure, at least one corner is connected with one end of the corresponding bur structure.
10. The electrode structure of claim 7, wherein the polygonal electrode body is a regular polygonal electrode body.
11. An electrode patch, comprising: an electrode structure as claimed in any one of claims 1 to 10.
12. The electrode patch as claimed in claim 11, further comprising an insulating layer and a skin-friendly layer disposed in a stack;
the electrode structure is positioned between the insulating layer and the skin-friendly layer, and an electrode main body of the electrode structure is used for being electrically connected with a power supply;
and one side of the skin-friendly layer, which is far away from the insulating layer, is used for being attached to the surface of the skin.
13. The electrode patch as claimed in claim 12, wherein the insulating layer has a receiving groove on a side thereof adjacent to the skin-friendly layer;
the electrode structure is embedded in the accommodating groove.
14. A cell-division inhibiting device comprising: a power source, and an electrode patch according to any one of claims 11-13;
and the electrode main body of the electrode structure in the electrode patch is electrically connected with the power supply.
15. The device according to claim 14, wherein the power source is an alternating current power source; or the power supply is a pulse power supply.
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| CN202110120744.7A CN112933407A (en) | 2021-01-28 | 2021-01-28 | Electrode structure, electrode patch and cell division suppression device |
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Cited By (1)
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| CN113509646A (en) * | 2021-08-13 | 2021-10-19 | 杭州维纳安可医疗科技有限责任公司 | Electrode patch, cell division inhibition device and control method thereof |
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