CN117412742A - 治疗特发性肺纤维化的辣椒素衍生物 - Google Patents

治疗特发性肺纤维化的辣椒素衍生物 Download PDF

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Publication number
CN117412742A
CN117412742A CN202280039778.6A CN202280039778A CN117412742A CN 117412742 A CN117412742 A CN 117412742A CN 202280039778 A CN202280039778 A CN 202280039778A CN 117412742 A CN117412742 A CN 117412742A
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CN
China
Prior art keywords
group
straight
compound
phenyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN202280039778.6A
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English (en)
Chinese (zh)
Inventor
埃里克·拉格
卢卡斯·阿尔特波斯特
托尔斯滕·哈尔森
波米·弗雷梅兹
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Aixin Quan Co
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Aixin Quan Co
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Publication date
Application filed by Aixin Quan Co filed Critical Aixin Quan Co
Publication of CN117412742A publication Critical patent/CN117412742A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN202280039778.6A 2021-06-02 2022-06-01 治疗特发性肺纤维化的辣椒素衍生物 Pending CN117412742A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20210693 2021-06-02
NO20210693A NO346587B1 (en) 2021-06-02 2021-06-02 Capsaicin derivatives in the treatment of idiopathic pulmonary fibrosis
PCT/EP2022/064876 WO2022253884A1 (en) 2021-06-02 2022-06-01 Capsaicin derivatives in the treatment of idiopathic pulmonary fibrosis

Publications (1)

Publication Number Publication Date
CN117412742A true CN117412742A (zh) 2024-01-16

Family

ID=82115682

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280039778.6A Pending CN117412742A (zh) 2021-06-02 2022-06-01 治疗特发性肺纤维化的辣椒素衍生物

Country Status (6)

Country Link
US (1) US20240277637A1 (enExample)
EP (1) EP4346789A1 (enExample)
JP (1) JP2024520650A (enExample)
CN (1) CN117412742A (enExample)
NO (1) NO346587B1 (enExample)
WO (1) WO2022253884A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO348880B1 (en) * 2023-03-13 2025-06-30 Axichem Ab Physical performance aid

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10237423A1 (de) * 2002-08-16 2004-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen
NO20034069L (no) 2003-09-12 2005-03-14 Aximed As Fremstilling og bruk av capsaicinderivater
ES2854732T3 (es) * 2011-07-07 2021-09-22 Eva Millqvist Producto antitusivo
WO2015160842A1 (en) * 2014-04-14 2015-10-22 Flex Pharma, Inc. Methods and formulatiions of capsaicinoids and capsinoids
WO2017160156A1 (en) * 2016-03-18 2017-09-21 Axichem Ab Synthetic capasaicin analogs as trpv1 agonists
CN113366000A (zh) * 2018-09-18 2021-09-07 百时美施贵宝公司 作为lpa拮抗剂的氧杂双环酸
WO2020160225A1 (en) * 2019-01-30 2020-08-06 Ohio State Innovation Foundation ESTROGEN RECEPTOR BETA (ERβ) AGONISTS FOR THE TREATMENT OF FIBROTIC CONDITIONS
WO2020191501A1 (en) * 2019-03-27 2020-10-01 Algernon Pharmaceuticals Inc. Methods and uses of bemithyl and derivatives for treating lung disease, fatty liver disease, and kidney disorders
US20200354374A1 (en) * 2019-05-06 2020-11-12 Inspira, LLC Chemical Entities, Pharmaceutical Formulations, and Methods for Treating Fibrosis
WO2020259528A1 (zh) * 2019-06-25 2020-12-30 北京泰德制药股份有限公司 治疗特发性肺纤维化的方法
NO345530B1 (en) 2020-03-20 2021-03-29 Axichem As Synthesis of capsaicin derivatives

Also Published As

Publication number Publication date
WO2022253884A4 (en) 2023-01-12
EP4346789A1 (en) 2024-04-10
US20240277637A1 (en) 2024-08-22
NO20210693A1 (enExample) 2022-10-17
NO346587B1 (en) 2022-10-17
JP2024520650A (ja) 2024-05-24
WO2022253884A1 (en) 2022-12-08

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