CN117297082A - Meal replacement composition for inspection and preparation method thereof - Google Patents

Meal replacement composition for inspection and preparation method thereof Download PDF

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Publication number
CN117297082A
CN117297082A CN202311440967.7A CN202311440967A CN117297082A CN 117297082 A CN117297082 A CN 117297082A CN 202311440967 A CN202311440967 A CN 202311440967A CN 117297082 A CN117297082 A CN 117297082A
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parts
vitamin
meal replacement
replacement composition
inspection
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杨克炜
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Yirun Health Industry Guangzhou Co ltd
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Yirun Health Industry Guangzhou Co ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production

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  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pediatric Medicine (AREA)
  • Inorganic Chemistry (AREA)
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Abstract

The invention provides a meal replacement composition for inspection and a preparation method thereof, wherein the meal replacement composition for inspection comprises the following components: proteins, dietary fibers, carbohydrates, fats, vitamins, minerals, prebiotics, and auxiliary additives. By adding a proper amount of dietary fiber as an auxiliary for clearing the intestines, the intestinal peristalsis can be stimulated, the intestinal tract is promoted to empty, the consumption of at least half of other auxiliary cathartics by an inspector is reduced, sufficient energy can be provided for human bodies to maintain vital movements by matching with protein and carbohydrate, adverse reactions such as hypodynamia, dizziness, even hypoglycemia and the like are avoided, meanwhile, vitamins and minerals are added, the electrolyte balance of the human bodies is maintained, prebiotics are beneficial to regulating the balance of intestinal flora, and catechin in the auxiliary additive has good promoting effect on the health of the intestinal tract and can reduce the damage to the intestinal tract in the preparation process of the intestinal tract.

Description

Meal replacement composition for inspection and preparation method thereof
Technical Field
The invention relates to the technical field of medical diet, in particular to a meal replacement composition for inspection and a preparation method thereof.
Background
With the rise of health consciousness, more and more people consider that regular physical examination is necessary, and for the digestive department, the development of digestive endoscopes is rapid, and the acceptance and acceptance of gastrointestinal endoscopy by the masses are on an increasing trend. The clean intestinal tract provides basic conditions for smooth insertion of a lens, observation of a colonic mucosa, accurate acquisition of biopsy tissue specimens, excision of polyps and the like, and particularly, the detection rate of intestinal polyps, adenoma and intestinal cancers is higher and higher, so that a plurality of patients benefit, but the intestinal tract preparation quality of each patient is found to reach the standard in the clinical application process, so that the intestinal tract preparation quality is improved, and the problems of aggravating physical and psychological burden of the patients caused by invalid examination and repeated examination are solved. At present, two methods for cleaning intestinal tracts are mainly adopted, namely, a control method of low-slag diet such as liquid diet is adopted in a few days before examination, so that the excrement in the intestinal tracts is discharged and reduced, and then diarrhea is carried out by adopting laxatives such as senna leaves and the like; secondly, the patient is bowel cleared with a synthetic laxative such as magnesium sulfate, phosphate or PEG.
The traditional intestinal tract preparation early-stage requires a slag-free or semi-fluid slag-free diet 3 days before examination, and a late fluid diet is used for the day before examination, and then a certain laxative is assisted to empty the intestines and the stomach, and then the slag-free or semi-fluid slag-free diet can be used for heavy load of adverse effects such as nitrogen balance, abnormal blood sugar, metabolic disorder, subjective tolerance reduction and the like on diabetics, tumor patients, malnutrition and people with digestive tract nutrition. Dietary preparation often requires patients to fast food vegetables, fruits, meats, vitamins, minerals and proteins, which can affect gastrointestinal motility, especially for patients suffering from gastrointestinal motility disorders, such as constipation, resulting in reduced patient compliance. The patient can suffer from poor energy, reduced tolerance, increased gastrointestinal reactions, and adverse reactions such as debilitation, dizziness, and even hypoglycemia due to diet restriction before colonoscopy. Thus, two difficulties often face in making dietary adjustments, namely what to eat and how much to eat properly. When a gastroenterologist opens a colonoscopy, he or she often worry about his or her unclear interpretation or incomplete content of his or her diet preparation to the patient, and not fully understand or sufficiently attach his or her attention to the patient, affecting the quality of the intestinal tract preparation. However, the large number of patients at the digestive clinic and the heavy workload do not allow the physician sufficient time to specify dietary precautions to the patient during bowel preparation. Therefore, a simple standard and effective diet preparation method is provided, and a prepackaged diet mode is adopted, so that an inspection meal replacement composition is provided, the ingestion mode is simple, the interpretation time of clinicians can be saved, the workload of medical staff is reduced, the tolerance and compliance of patients can be improved, the inspection meal replacement composition can promote intestinal peristalsis and evacuation, improve the cleanliness of the intestinal tract, reduce the dosage of the follow-up laxatives, reduce the pressure of the intestinal tract and ensure that the preparation of the intestinal tract is successfully completed.
Disclosure of Invention
The invention aims to provide a meal replacement composition for examination and a preparation method thereof, which have good intestinal tract cleaning effect, are safe to a human body and easy to apply, and ensure that intestinal tract preparation is successfully completed.
In order to achieve the above object, the present invention provides an inspection meal replacement composition comprising the following components: proteins, dietary fibers, carbohydrates, fats, vitamins, minerals, prebiotics, and auxiliary additives. The protein is soy protein isolate and/or rice protein and/or protein peptide and/or whey protein and/or soy protein powder; the dietary fiber is konjaku flour and/or oat beta-glucan and/or fructooligosaccharides and/or resistant dextrin; the carbohydrate is maltodextrin and/or oat; the fat is one or more of corn oil, sunflower seed oil, soybean oil, rapeseed oil and coconut oil, and vegetable fat powder can be selected as the fat; the vitamins are 2 or more than 2 combinations of vitamin B1, vitamin B2, vitamin B3, pantothenic acid, vitamin B6, biotin, folic acid, vitamin A and vitamin E; the mineral is a combination of sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate and calcium carbonate; the prebiotics are at least 2 of inulin, xylooligosaccharide, isomaltooligosaccharide, sorbitol, lactitol, stachyose and xylitol; the auxiliary additive comprises an albumin-glucan-catechin ternary graft, wherein the grafting amount of catechin in the albumin-glucan-catechin ternary graft is 4.81-4.96mg/g.
Preferably, the meal replacement composition for inspection comprises the following components: soy protein isolate, protein peptide, oat beta-glucan, fructooligosaccharides, resistant dextrins, maltodextrin, corn oil, coconut oil, vitamin B1, vitamin B2, folic acid, vitamin a, vitamin E, sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate, calcium carbonate, inulin, sorbitol, lactitol and co-additives.
Further preferably, the meal replacement composition for inspection comprises the following components in parts by weight: 20-30 parts of soybean protein isolate, 10-15 parts of protein peptide, 3-9 parts of oat beta-glucan, 3-6 parts of fructo-oligosaccharide, 2-4 parts of resistant dextrin, 20-25 parts of maltodextrin, 10-17 parts of corn oil, 15-20 parts of coconut oil, 10.01-0.5 part of vitamin B, 20.01-0.5 part of vitamin B, 0.01-0.5 part of folic acid, 0.01-0.5 part of vitamin A, 0.01-1.5 part of vitamin E, 0.01-1.5 part of sodium chloride, 0.01-1 part of ferrous sulfate, 0.01-1 part of zinc gluconate, 0.01-1 part of magnesium sulfate, 0.01-1 part of calcium carbonate, 4-8 parts of inulin, 2-8 parts of sorbitol, 2-8 parts of lactitol and 10-15 parts of auxiliary additive.
Further preferably, the meal replacement composition for inspection comprises the following components in parts by weight: 26 parts of soybean protein isolate, 15 parts of protein peptide, 6 parts of oat beta-glucan, 6 parts of fructooligosaccharide, 3 parts of resistant dextrin, 24 parts of maltodextrin, 15 parts of corn oil, 18 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 13 parts of auxiliary additive.
Preferably, the auxiliary additive is an emulsion-like auxiliary additive, which further comprises lutein ester and sunflower seed oil.
Further preferably, the preparation method of the auxiliary additive comprises the following steps: the lutein ester is dispersed into sunflower seed oil to obtain an oil phase, and then the oil phase is dispersed into an egg white protein-glucan-catechin ternary graft water phase to obtain the emulsion auxiliary additive.
Further preferably, the mass ratio of the lutein ester to the sunflower seed oil is 1:10, and the mass ratio of the water phase to the oil phase is 9:1.
Preferably, the preparation method of the ternary albumin-glucan-catechin graft comprises the following steps: 1) Dissolving 0.5g of glucan in 50mL of deionized water, adding 1mL of 5mol/L hydrogen peroxide solution and 0.25g of ascorbic acid, reacting for 2.5h at 25 ℃, adding 0.1016g of catechin, stirring thoroughly, continuing to react for 24h, and then placing the solution in a dialysis bag for dialysis at room temperature for 48-36h to remove free polyphenol to obtain glucan-epicatechin grafts; 2) Adding 0.5g of egg white protein into the dialyzed solution, regulating the pH value to 7.0 by using 0.1mol/L sodium hydroxide, stirring for 3 hours to obtain a mixed solution, freeze-drying the mixed solution to obtain a powdery mixture, and incubating the powdery mixture for 3 days at 65 ℃ and 80% relative humidity to obtain the egg white protein-glucan-catechin graft.
The invention also provides a preparation method of the meal replacement composition for inspection, which is used for preparing the meal replacement composition for inspection and comprises the following steps of:
sequentially sieving proteins, dietary fibers and carbohydrates through a 100-mesh sieve, sequentially mixing with fat for 30min, then adding vitamins and minerals, continuously mixing for 10-20min until the mixture is uniform, and granulating to obtain first granules;
step two, fully mixing the first particles with the prebiotic powder, and sealing, bagging and sealing to obtain a first product;
preparing an egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive, filling the auxiliary additive into a capsule container, and sealing and preserving the auxiliary additive to obtain a second product;
and step four, combining and packaging the first product and the second product to obtain the meal replacement composition for inspection.
The meal replacement composition for examination can be applied to the preparation process of intestinal tract cleaning, and the using method comprises the following steps: the meal replacement composition for examination is taken as three meals of early, middle and late, and the dosage of each meal is 130-190g. The first product is dissolved in warm water at 55-66 ℃, then the capsules of the second product are torn open to enable the auxiliary additive in the form of internal emulsion to be added into the solution, and the solution is taken after stirring, wherein one first product is matched with one second product capsule.
The beneficial effects of the invention are as follows: the meal replacement composition for examination can stimulate intestinal peristalsis, promote intestinal tract evacuation, reduce the usage amount of at least half of other auxiliary cathartics used by an inspector, and can provide sufficient energy for human bodies to maintain vital activities by matching with proteins and carbohydrates so as to avoid adverse reactions such as debilitation, dizziness, even hypoglycemia and the like, and simultaneously add vitamins and minerals so as to maintain the electrolyte balance of the human bodies, so that prebiotics are beneficial to regulating the intestinal flora balance, catechin in auxiliary additives has good promotion effect on intestinal health, and damage to intestinal tracts in the intestinal tract preparation process can be reduced. The meal replacement composition for inspection is a granular preparation matched with a liquid capsule, has simple preparation process and convenient and quick ingestion, can effectively increase the intestinal tract preparation quality of a user, increases the probability of one-time passing inspection of the user, reduces the pain degree of the user and improves the compliance of the user.
Detailed Description
The embodiments described below are only some, but not all, embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The present invention relates to a meal replacement composition for inspection, comprising the following components: proteins, dietary fibers, carbohydrates, fats, vitamins, minerals, prebiotics, and auxiliary additives. The protein is soybean protein isolate and/or rice protein and/or protein peptide and/or whey protein and/or soybean protein powder. The dietary fiber is konjaku flour and/or oat beta-glucan and/or fructooligosaccharides and/or resistant dextrin. The carbohydrate is maltodextrin and/or oat. The fat is one or more of corn oil, sunflower seed oil, soybean oil, rapeseed oil and coconut oil, and can be vegetable fat powder with a tissue structure similar to that of infant milk powder. It has good water absorption, emulsion tenninal, reliability, instant solubility, ductility and unique nutrition deficiency. The vitamins are 2 or more than 2 combinations of vitamin B1, vitamin B2, vitamin B3, pantothenic acid, vitamin B6, biotin, folic acid, vitamin A and vitamin E; the mineral is a combination of sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate and calcium carbonate; the prebiotics are at least 2 of inulin, xylooligosaccharide, isomaltooligosaccharide, sorbitol, lactitol, stachyose and xylitol. The auxiliary additive comprises an albumin-glucan-catechin ternary graft, wherein the grafting amount of catechin in the albumin-glucan-catechin ternary graft is 4.81-4.96mg/g.
The dietary fiber has various physiological effects by adding the dietary fiber, and the main effects are relaxing bowel, so that on one hand, the dietary fiber is large in volume, can stimulate intestinal peristalsis, promote stool, reduce the residence time of food in intestinal tracts, and keep moisture difficult to absorb; on the other hand, the dietary fiber is fermented in the large intestine by bacteria, and directly absorbs the moisture in the fiber, so that the volume and the moisture of the excrement are increased, the excrement is softened, and the effect of relaxing the bowels is achieved. The konjak flour can increase the function of intestinal canal, inhibit the absorption of water by small intestine and the absorption of water in intestinal wall into intestinal canal, thereby softening stool, relaxing bowels and accelerating the excretion of toxic substances. Oat beta-glucan oat B-glucan is a soluble dietary fiber, and the oat beta-glucan is a linear polysaccharide formed by connecting B-D-glucopyranose residues through (1-3) or (1-4) -B-D-sugar bonds, can prolong satiety, relieve constipation, improve intestinal flora composition and improve intestinal functions. Oat B-glucan with different molecular weights can promote proliferation of Lactobacillus and Bidobacterium in intestinal tracts, inhibit growth of potential pathogenic bacteria, and can improve intestinal health by synergistic effect with other prebiotics. Oat B-glucan can also ferment in the colon to increase the amount of butyric acid in the gut, and butyric acid can promote normal intestinal cell growth to inhibit cancer cell growth, and reduce intestinal inflammation. Fructo-oligosaccharide is a water-soluble dietary fiber, and can reduce serum cholesterol and improve fat metabolism after long-term administration. Animal and human experiments prove that the composition is suitable for the treatment of the skin. The fructo-oligosaccharide has the following physiological functions of being utilized by beneficial bacteria such as bifidobacteria and the like, and has the effect of bidirectionally regulating intestinal tracts. After the human body ingests fructo-oligosaccharide, the number of the beneficial bacteria bifidobacteria in the human body can inhibit growth and reproduction of exogenous pathogenic bacteria and inherent putrefying bacteria in the intestines, such as salmonella, and the like, reduce growth and accumulation of putrefying substances in the intestines, promote intestinal peristalsis, and prevent constipation and diarrhea. The fructo-oligosaccharide is fermented by bacteria in large intestine to generate L-lactic acid, which can dissolve minerals such as calcium, magnesium, iron, etc., and promote the absorption of minerals by human body. The resistant dextrin is prepared from starch, is a low-calorie glucan prepared by extracting and refining indigestible components of baked dextrin by an industrial technology, belongs to low-molecular water-soluble dietary fibers, and has the functions of reducing weight, reducing blood fat, reducing blood sugar, regulating intestinal flora and the like. Can inhibit the digestion and absorption of various saccharides by human small intestine, and can obviously inhibit the rise of blood sugar and insulin.
Maltodextrin is a starch derivative which is prepared from starch or starch matter serving as a raw material through low-level hydrolysis by an enzyme method, refining and spray drying and does not contain free starch. The maltodextrin has good fluidity, no peculiar smell, good solubility, strong heat resistance, low hygroscopicity, no agglomeration, no masking of the flavor and fragrance of other raw materials even if used in a state of high concentration, good carrier effect, and the addition of a proper amount of maltodextrin can improve necessary energy for human body and prevent the occurrence of the problems of blood sugar and the like caused by abnormal diet. Oat is warm in nature and sweet in taste, and has the effects of strengthening spleen, tonifying qi, tonifying deficiency, suppressing sweating, nourishing stomach and moistening intestines. It can also improve blood circulation and relieve pressure brought by life and work; the minerals such as calcium, phosphorus, iron, zinc and the like also have the effects of preventing osteoporosis, promoting wound healing and preventing anemia, and are excellent calcium supplementing products. Moreover, the extremely abundant linoleic acid in oat is also beneficial to enhancing physical strength, and can improve satiety and patient compliance.
By adding vitamins, the recovery of intestinal surgery patients with intestinal dysfunction can be assisted, the immunity of the organism can be improved, the epithelial cells can be protected and repaired, and the B vitamins such as vitamin B1, B2, nicotinic acid and pantothenic acid which are easy to lose in surgery or wound can be supplemented, so that the body function is improved.
The added minerals are used for truly regulating electrolyte balance caused by mineral elements required by human body and maintaining human health.
The invention also provides that a proper amount of prebiotics are added, and as the prebiotics cannot be decomposed, absorbed and utilized by human bodies, after the prebiotics reach the colon through the alimentary canal, some prebiotics can be decomposed and utilized by colonic flora, thereby promoting the growth of colonic flora, and having important significance in improving intestinal microecology and promoting metabolism of lipid, protein and minerals.
Further, in order to improve the forward promotion effect of the meal replacement composition for examination on intestinal tracts, the invention provides that a proper amount of auxiliary additive is added, and the main component of the auxiliary additive is ternary grafts of egg white protein, glucan and catechin. Catechins, also known as catechin and catechin (Caredhieacid), are phenolic active substances extracted from natural plants such as tea, and are prominent in anti-inflammatory, antibacterial, antiviral and antioxidant effects, and can inhibit pathogenic bacteria (such as botulinum) of human body, and meanwhile, do not harm the reproduction of beneficial bacteria (such as lactobacillus), so that the catechin has the function of regulating intestinal tract, and therefore, the damage degree of the catechin to the intestinal tract in the preparation process of the intestinal tract can be effectively reduced. Egg white protein is also a good energy supply substance, and the stability between the egg white protein and catechin can be improved by combining the egg white protein and the catechin together. The introduction of dextran reduces the surface hydrophobicity of the protein. The results of the emulsifying activity and the emulsifying stability show that the covalent bonding of the glucan remarkably improves the emulsifying capacity of the egg white protein under the neutral condition, and the ternary graft has higher solubility and stronger antioxidant capacity. The lutein ester has the effects of resisting oxidation, resisting inflammation, reducing blood fat and the like, has the effects of resisting fatigue, delaying aging, improving body immunity and the like, has good protection effect on human bodies, and can prevent the body function from being reduced due to abnormal feeding, the lutein ester is obtained by esterifying active light groups at two ends of lutein molecules, the stability is improved to a certain extent, and free lutein is released by hydrolysis after being taken into the human bodies and then absorbed into blood. The ternary graft of the egg white protein, the glucan and the catechin has ideal emulsion stabilizing capability and antioxidant activity, and can improve the retention rate of lutein ester. The covalent bonding of the glucan plays a role in thickening an interface layer, so that the interface protein is protected from being hydrolyzed by protease, the lutein of the ternary graft group of the egg white protein, the glucan and the epicatechin has good stability, and most of the lutein cannot be absorbed until the period of small intestine, so that the bioavailability is high.
Preferably, the meal replacement composition for inspection comprises the following components: soy protein isolate, protein peptide, oat beta-glucan, fructooligosaccharides, resistant dextrins, maltodextrin, corn oil, coconut oil, vitamin B1, vitamin B2, folic acid, vitamin a, vitamin E, sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate, calcium carbonate, inulin, sorbitol, lactitol and co-additives.
Further preferably, the meal replacement composition for inspection comprises the following components in parts by weight: 20-30 parts of isolated soy protein, including, but not limited to, 20 parts, 22 parts, 24 parts, 26 parts, 28 parts; 10-15 parts of protein peptide, including but not limited to 10 parts, 12 parts, 14 parts, 15 parts; 3-9 parts of oat beta-glucan, including, but not limited to, 3 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts; 3-6 parts of fructo-oligosaccharides including, but not limited to, 3 parts, 4 parts, 5 parts, 6 parts; 2-4 parts of resistant dextrin, including but not limited to 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts; maltodextrin 20-25 parts including, but not limited to, 20 parts, 21 parts, 22 parts, 24 parts, 25 parts; 10-17 parts of corn oil, including, but not limited to, 10 parts, 12 parts, 14 parts, 15 parts, 17 parts; 15-20 parts of coconut oil, including, but not limited to, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts; 10.01-0.5 parts of vitamin B, including, but not limited to, 0.01 parts, 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, 0.35 parts, 0.4 parts, 0.45 parts, 0.5 parts; 20.01-0.5 parts of vitamin B, including, but not limited to, 0.01 parts, 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, 0.35 parts, 0.4 parts, 0.45 parts, 0.5 parts; 0.01-0.5 parts of folic acid including, but not limited to, 0.01 parts, 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, 0.35 parts, 0.4 parts, 0.45 parts, 0.5 parts; 0.01-0.5 parts of vitamin A, including but not limited to 0.01 parts, 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, 0.35 parts, 0.4 parts, 0.45 parts, 0.5 parts; 0.01-0.5 parts of vitamin E, including, but not limited to, 0.01 parts, 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, 0.35 parts, 0.4 parts, 0.45 parts, 0.5 parts; 0.01 to 1.5 parts of sodium chloride, including but not limited to 0.01 part, 0.08 part, 0.1 part, 0.4 part, 0.6 part, 0.8 part, 1.0 part, 1.2 part, 1.5 part; ferrous sulfate 0.01-1 parts including, but not limited to, 0.01 parts, 0.08 parts, 0.1 parts, 0.4 parts, 0.6 parts, 0.8 parts, 1.0 parts; 0.01-1 part of zinc gluconate including, but not limited to, 0.01 part, 0.08 part, 0.1 part, 0.4 part, 0.6 part, 0.8 part, 1.0 part; 0.01-1 part of magnesium sulfate, including but not limited to 0.01 part, 0.08 part, 0.1 part, 0.4 part, 0.6 part, 0.8 part, 1.0 part; 0.01-1 part of calcium carbonate, including but not limited to 0.01 part, 0.08 part, 0.1 part, 0.4 part, 0.6 part, 0.8 part, 1.0 part; 4-8 parts of inulin, including, but not limited to, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts; 2-8 parts of sorbitol, including, but not limited to, 2 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts; 2-8 parts of lactitol, including, but not limited to, 2 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts; 10-15 parts of auxiliary additives, including but not limited to 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts.
Preferably, the meal replacement composition for inspection comprises the following components in parts by weight: 26 parts of soybean protein isolate, 15 parts of protein peptide, 6 parts of oat beta-glucan, 6 parts of fructooligosaccharide, 3 parts of resistant dextrin, 24 parts of maltodextrin, 15 parts of corn oil, 18 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 13 parts of auxiliary additive.
Preferably, the auxiliary additive is an emulsion-like auxiliary additive, which further comprises lutein ester and sunflower seed oil. The preparation method of the auxiliary additive comprises the following steps: the lutein ester is dispersed into sunflower seed oil to obtain an oil phase, and then the oil phase is dispersed into an egg white protein-glucan-catechin ternary graft water phase to obtain the emulsion auxiliary additive. The mass ratio of the lutein ester to the sunflower seed oil is 1:10, and the mass ratio of the water phase to the oil phase is 9:1.
The preparation method of the ternary albumin-glucan-catechin graft comprises the following steps: 1) Dissolving 0.5g of glucan in 50mL of deionized water, adding 1mL of 5mol/L hydrogen peroxide solution and 0.25g of ascorbic acid, reacting for 2.5h at 25 ℃, adding 0.1016g of catechin, stirring thoroughly, continuing to react for 24h, and placing the solution in a dialysis bag (molecular weight 8000-14000) for dialysis at room temperature for 48-36h to remove free polyphenol to obtain glucan-epicatechin graft; 2) Adding 0.5g of egg white protein into the dialyzed solution, regulating the pH value to 7.0 by using 0.1mol/L sodium hydroxide, stirring for 3 hours to obtain a mixed solution, freeze-drying the mixed solution to obtain a powdery mixture, and incubating the powdery mixture for 3 days at 65 ℃ and 80% relative humidity to obtain the egg white protein-glucan-catechin graft.
The invention also provides a preparation method of the meal replacement composition for inspection, which is used for preparing the meal replacement composition for inspection and comprises the following steps of:
sequentially sieving proteins, dietary fibers and carbohydrates through a 100-mesh sieve, sequentially mixing with fat for 30min, then adding vitamins and minerals, continuously mixing for 10-20min until the mixture is uniform, and granulating to obtain first granules;
step two, fully mixing the first particles with the prebiotic powder, and sealing, bagging and sealing to obtain a first product;
preparing an egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive, filling the auxiliary additive into a capsule container, and sealing and preserving the auxiliary additive to obtain a second product;
and step four, combining and packaging the first product and the second product to obtain the meal replacement composition for inspection.
Example 1
The embodiment provides an inspection meal replacement composition, which comprises the following components in parts by weight: 20 parts of soybean protein isolate, 14 parts of protein peptide, 5 parts of oat beta-glucan, 4 parts of fructooligosaccharide, 3 parts of resistant dextrin, 21 parts of maltodextrin, 12 parts of corn oil, 16 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 11 parts of auxiliary additives (egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive).
The preparation method of the meal replacement composition for inspection comprises the following steps:
sequentially sieving raw materials of soy protein isolate, protein peptide, oat beta-glucan, fructo-oligosaccharide, resistant dextrin and maltodextrin through a 100-mesh sieve, sequentially mixing with fat for 30min, then adding vitamin B1, vitamin B2, folic acid, vitamin A, vitamin E, sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate and calcium carbonate, continuously mixing for 10-20min until the raw materials are uniform, and granulating to obtain first granules;
step two, fully mixing the first particles with inulin, sorbitol and lactitol, and sealing, bagging and sealing to obtain a first product;
preparing an egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive, filling the auxiliary additive into a capsule container, and sealing and preserving the auxiliary additive to obtain a second product;
and step four, combining and packaging the first product and the second product to obtain the meal replacement composition for inspection.
Example 2
The embodiment provides an inspection meal replacement composition, which comprises the following components in parts by weight: 22 parts of soybean protein isolate, 12 parts of protein peptide, 6 parts of oat beta-glucan, 4 parts of fructooligosaccharide, 3 parts of resistant dextrin, 24 parts of maltodextrin, 14 parts of corn oil, 17 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 12 parts of auxiliary additives (egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive).
The preparation method of the meal replacement composition for examination was the same as in example 1.
Example 3
The embodiment provides an inspection meal replacement composition, which comprises the following components in parts by weight: 24 parts of soybean protein isolate, 15 parts of protein peptide, 5 parts of oat beta-glucan, 5 parts of fructooligosaccharide, 3 parts of resistant dextrin, 25 parts of maltodextrin, 15 parts of corn oil, 17 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 12 parts of auxiliary additives (egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive).
The preparation method of the meal replacement composition for examination was the same as in example 1.
Example 4
The embodiment provides an inspection meal replacement composition, which comprises the following components in parts by weight: 26 parts of soybean protein isolate, 15 parts of protein peptide, 6 parts of oat beta-glucan, 6 parts of fructooligosaccharide, 3 parts of resistant dextrin, 24 parts of maltodextrin, 15 parts of corn oil, 18 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 13 parts of auxiliary additives (egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive).
The preparation method of the meal replacement composition for examination was the same as in example 1.
Example 5
The embodiment provides an inspection meal replacement composition, which comprises the following components in parts by weight: 28 parts of soybean protein isolate, 10 parts of protein peptide, 7 parts of oat beta-glucan, 6 parts of fructooligosaccharide, 3 parts of resistant dextrin, 25 parts of maltodextrin, 15 parts of corn oil, 20 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 13 parts of auxiliary additives (egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive).
The preparation method of the meal replacement composition for examination was the same as in example 1.
Example 6
The embodiment provides an inspection meal replacement composition, which comprises the following components in parts by weight: 26 parts of soybean protein isolate, 15 parts of protein peptide, 6 parts of oat beta-glucan, 6 parts of fructooligosaccharide, 3 parts of resistant dextrin, 24 parts of maltodextrin, 15 parts of corn oil, 18 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 0 part of auxiliary additive (egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive).
The preparation method of the meal replacement composition for inspection comprises the following steps: sequentially sieving raw materials of soy protein isolate, protein peptide, oat beta-glucan, fructo-oligosaccharide, resistant dextrin and maltodextrin through a 100-mesh sieve, sequentially mixing with fat for 30min, then adding vitamin B1, vitamin B2, folic acid, vitamin A, vitamin E, sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate and calcium carbonate, continuously mixing for 10-20min until the raw materials are uniform, and granulating to obtain first granules;
and step two, fully mixing the first particles with inulin, sorbitol and lactitol, and sealing, bagging and sealing to obtain the meal replacement composition for inspection.
The patients in examples 1 to 6 were examined endoscopically by using the meal replacement composition for examination prepared in the examples of the present invention, and the meal replacement composition for examination was eaten as three meals, namely, early meal, medium meal and late meal, wherein the meal replacement composition for examination in examples 1 to 5 comprises a granular first product and a capsule second product, the quality of the first product is 130 to 190g per bag, and one capsule contains 5ml of emulsion. The patient dissolves the first product in warm water at 55-66 ℃, then tears the capsule of the second product to add the internal emulsion auxiliary additive into the solution, and takes after stirring. The composition of example 6 was taken without capsules, and only after dissolution. Run out of food before 6 pm; the leakage guiding agent compound polyethylene glycol electrolyte powder (III) is 1 bag and 1L of warm water (250 ml is taken every 15 minutes and is taken in one hour) for the first time at 8 points in night; the following morning is followed by 1 bag of compound polyethylene glycol electrolyte powder (III) and 2L of warm water (250 ml is taken every 15 minutes and is taken for two hours), (each bag contains polyethylene glycol 4000.000 g, anhydrous sodium sulfate 5.700g, sodium chloride 1.460g, potassium chloride 0.750g, sodium bicarbonate 1.680g and warm boiled water 1L is dissolved), and then the patients are fasted and forbidden. The patient walks back and forth during the taking period, gently kneads the abdomen, and the patient urinates to the stool to be clear (colorless or yellow transparent water sample).
Comparative example 1
The method adopts the prior art: the patient can prepare low-dreg diet by himself with three meals, including noodles, rice gruel, lotus root starch, egg custard, etc. Three meals of self-contained low-dreg diet (noodles, rice gruel and the like) are checked before one day, 1 bag of compound polyethylene glycol electrolyte powder (III) and 1L of warm water (250 ml is taken every 15 minutes and is taken in one hour) are used for the first time at 8 points in night; the following morning is followed by 2 bags of compound polyethylene glycol electrolyte powder (III) and 2L of warm water (250 ml is taken every 15 minutes and is taken in two hours), (each bag contains polyethylene glycol 4000.000 g, anhydrous sodium sulfate 5.700g, sodium chloride 1.460g, potassium chloride 0.750g, sodium bicarbonate 1.680g and 1L of warm boiled water for dissolution), and the polyethylene glycol is taken after being taken for 30ml of simethicone, and the water is forbidden after being forbidden. The patient walks back and forth during the taking period, gently kneads the abdomen, and the patient urinates to the stool to be clear (colorless or yellow transparent water sample).
Examples combined control groups were 125 persons/group and intestinal condition scores were made for each of the above groups.
And grading the cleanliness of the intestinal tract after the second drainage, and counting the abdominal distension, nausea, vomiting and dizziness and hypoglycemia of the inspector in the endoscopic examination process and the compliance statistics of intestinal tract preparation of the patient.
Intestinal cleanliness score: the right half colon (cecum and ascending colon), mid-section colon (liver curvature, transverse colon, spleen curvature) and left half colon (descending colon, sigmoid colon and rectum) were scored separately using the Boston scale (BBPS) scoring criteria, with a total of 3 segments of bowel total score (0-9 points). All colonoscopy operations are completed and recorded synchronously by the same experienced endoscopist, and then a fixed endoscopist is trained and then evaluated according to the enteroscopy report and the recorded video, and the endoscopist does not know the specific situation of intestinal preparation before enteroscopy of the patient. The scoring data are shown in table 1.
In the endoscopic examination process, statistics of abdominal distension, nausea, vomiting and dizziness and hypoglycemia of the inspector are carried out: the nurses inquire about symptoms of abdominal pain, abdominal distension, nausea and vomiting of adverse reactions within 24 hours after the patients return to the room in the enteroscopy, and the number of patients with each symptom accounts for the proportion of the total number of the coloscopy at the same time. The statistics are shown in Table 2.
Patient intestinal tract preparation compliance statistics: after the intestinal tract preparation is finished, the patient judges the compliance of the patient to be qualified, and one non-compliance is judged to be unqualified. The statistics are shown in Table 3.
Table 1 intestinal cleanliness score
TABLE 2 statistics of abdominal distension, nausea, vomiting, dizziness and hypoglycemia of inspector during endoscopic procedures
Group of Number of examples Abdominal distension Nausea and vomiting Dizziness and hypoglycemia
Example 1 125 8 7 2
Example 2 125 8 5 1
Example 3 125 7 5 0
Example 4 125 6 4 0
Example 5 125 7 4 0
Example 6 125 12 13 4
Comparative example 1 125 27 16 20
Table 3 patient intestinal tract preparation compliance statistics
Group of Number of examples Number of pass cases Number of reject cases
Example 1 125 123 2
Example 2 125 123 2
Example 3 125 124 1
Example 4 125 125 0
Example 5 125 122 3
Example 6 125 118 7
Comparative example 1 125 100 25
From the above data, it can be seen that the meal replacement composition for examination provided in the examples has better patient compliance in the process of preparing intestinal tracts, higher receiving degree of meal replacement, better quality of intestinal tracts preparation, reduced discomfort feeling after examination of patients, and is beneficial to improving the accuracy of examination.
The meal replacement composition for examination provided by the invention can supplement energy required by activities for patients, and prevent adverse phenomena such as hypoglycemia and the like caused by incapacity of taking food, so that the compliance of the patients is effectively improved. The meal replacement composition for examination is added with a proper amount of dietary fibers, so that the intestinal peristalsis can be stimulated, and the intestinal tract is promoted to be emptied, thereby achieving the aim of reducing the dosage of the laxative in the subsequent process, and being more friendly to the intestinal tract. The auxiliary additive is properly added, and effective components such as catechin, egg white protein, lutein ester and the like are contained in the auxiliary additive, so that the auxiliary additive has the effects of protecting the intestinal tract, improving the resistance of a human body, preventing the resistance from being reduced in the preparation process of the intestinal tract and increasing the inspection difficulty.
The foregoing disclosure is only illustrative of the preferred embodiments of the present invention and is not to be construed as limiting the scope of the invention, which is defined by the appended claims.

Claims (9)

1. An inspection meal replacement composition, characterized in that it comprises the following components: proteins, dietary fibers, carbohydrates, fats, vitamins, minerals, prebiotics, and auxiliary additives; the protein is soy protein isolate and/or rice protein and/or protein peptide and/or whey protein; the dietary fiber is konjaku flour and/or oat beta-glucan and/or fructooligosaccharides and/or resistant dextrin; the carbohydrate is maltodextrin; the fat is one or more of corn oil, sunflower seed oil, soybean oil, rapeseed oil and coconut oil; the vitamins are 2 or more than 2 combinations of vitamin B1, vitamin B2, vitamin B3, pantothenic acid, vitamin B6, biotin, folic acid, vitamin A and vitamin E; the mineral is a combination of sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate and calcium carbonate; the prebiotics are at least 2 of inulin, xylooligosaccharide, isomaltooligosaccharide, sorbitol, lactitol, stachyose and xylitol; the auxiliary additive comprises an albumin-glucan-catechin ternary graft, wherein the grafting amount of catechin in the albumin-glucan-catechin ternary graft is 4.81-4.96mg/g.
2. The meal replacement composition for inspection according to claim 1, wherein the meal replacement composition for inspection comprises the following components: soy protein isolate, protein peptide, oat beta-glucan, fructooligosaccharides, resistant dextrins, maltodextrin, corn oil, coconut oil, vitamin B1, vitamin B2, folic acid, vitamin a, vitamin E, sodium chloride, ferrous sulfate, zinc gluconate, magnesium sulfate, calcium carbonate, inulin, sorbitol, lactitol and co-additives.
3. The meal replacement composition for inspection according to claim 2, wherein the meal replacement composition for inspection comprises the following components in parts by mass: 20-30 parts of soybean protein isolate, 10-15 parts of protein peptide, 3-9 parts of oat beta-glucan, 3-6 parts of fructo-oligosaccharide, 2-4 parts of resistant dextrin, 20-25 parts of maltodextrin, 10-17 parts of corn oil, 15-20 parts of coconut oil, 10.01-0.5 part of vitamin B, 20.01-0.5 part of vitamin B, 0.01-0.5 part of folic acid, 0.01-0.5 part of vitamin A, 0.01-1.5 part of vitamin E, 0.01-1.5 part of sodium chloride, 0.01-1 part of ferrous sulfate, 0.01-1 part of zinc gluconate, 0.01-1 part of magnesium sulfate, 0.01-1 part of calcium carbonate, 4-8 parts of inulin, 2-8 parts of sorbitol, 2-8 parts of lactitol and 10-15 parts of auxiliary additive.
4. The meal replacement composition for inspection according to claim 3, wherein the meal replacement composition for inspection comprises the following components in parts by mass: 26 parts of soybean protein isolate, 15 parts of protein peptide, 6 parts of oat beta-glucan, 6 parts of fructooligosaccharide, 3 parts of resistant dextrin, 24 parts of maltodextrin, 15 parts of corn oil, 18 parts of coconut oil, 10.05 parts of vitamin B, 20.05 parts of vitamin B, 0.05 part of folic acid, 0.05 part of vitamin A, 0.05 part of vitamin E, 0.3 part of sodium chloride, 0.06 part of ferrous sulfate, 0.08 part of zinc gluconate, 0.05 part of magnesium sulfate, 0.6 part of calcium carbonate, 5 parts of inulin, 5 parts of sorbitol, 4 parts of lactitol and 13 parts of auxiliary additive.
5. The inspection meal replacement composition of claim 1, wherein the auxiliary additive is an emulsion-like auxiliary additive further comprising lutein ester and sunflower seed oil.
6. The inspection meal replacement composition of claim 5, wherein the auxiliary additive is prepared by a process comprising: the lutein ester is dispersed into sunflower seed oil to obtain an oil phase, and then the oil phase is dispersed into an egg white protein-glucan-catechin ternary graft water phase to obtain the emulsion auxiliary additive.
7. The inspection meal replacement composition according to claim 6, wherein the mass ratio of lutein ester to sunflower seed oil is 1:10, and the mass percentage of the aqueous phase to the oil phase is 9:1.
8. The meal replacement composition for inspection according to claim 1, wherein the preparation method of the ternary albumin-dextran-catechin graft comprises the following steps: 1) Dissolving 0.5g of glucan in 50mL of deionized water, adding 1mL of 5mol/L hydrogen peroxide solution and 0.25g of ascorbic acid, reacting for 2.5h at 25 ℃, adding 0.1016g of catechin, stirring thoroughly, continuing to react for 24h, and then placing the solution in a dialysis bag for dialysis at room temperature for 48-36h to remove free polyphenol to obtain glucan-epicatechin grafts; 2) Adding 0.5g of egg white protein into the dialyzed solution, regulating the pH value to 7.0 by using 0.1mol/L sodium hydroxide, stirring for 3 hours to obtain a mixed solution, freeze-drying the mixed solution to obtain a powdery mixture, and incubating the powdery mixture for 3 days at 65 ℃ and 80% relative humidity to obtain the egg white protein-glucan-catechin graft.
9. A method for preparing the meal replacement composition for inspection, which is used for preparing the meal replacement composition for inspection according to any one of claims 1 to 8, characterized by comprising the steps of:
sequentially sieving proteins, dietary fibers and carbohydrates through a 100-mesh sieve, sequentially mixing with fat for 30min, then adding vitamins and minerals, continuously mixing for 10-20min until the mixture is uniform, and granulating to obtain first granules;
step two, fully mixing the first particles with the prebiotic powder, and sealing, bagging and sealing to obtain a first product;
preparing an egg white protein-glucan-catechin graft-lutein ester emulsion auxiliary additive, filling the auxiliary additive into a capsule container, and sealing and preserving the auxiliary additive to obtain a second product;
and step four, combining and packaging the first product and the second product to obtain the meal replacement composition for inspection.
CN202311440967.7A 2023-11-01 2023-11-01 Meal replacement composition for inspection and preparation method thereof Pending CN117297082A (en)

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