CN117083388A - 具有酰基CoA化合物还原活性的重组多肽 - Google Patents
具有酰基CoA化合物还原活性的重组多肽 Download PDFInfo
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- CN117083388A CN117083388A CN202280024848.0A CN202280024848A CN117083388A CN 117083388 A CN117083388 A CN 117083388A CN 202280024848 A CN202280024848 A CN 202280024848A CN 117083388 A CN117083388 A CN 117083388A
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- China
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- amino acid
- position corresponding
- acid residue
- phenylalanine
- alanine
- Prior art date
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- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
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- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
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- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01024—Succinate-semialdehyde dehydrogenase (NAD+) (1.2.1.24)
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- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01076—Succinate-semialdehyde dehydrogenase (acetylating) (1.2.1.76)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01079—Succinate-semialdehyde dehydrogenase (NADP+) (1.2.1.79)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/145—Clostridium
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- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021057313 | 2021-03-30 | ||
| JP2021-057313 | 2021-03-30 | ||
| PCT/JP2022/012463 WO2022209994A1 (ja) | 2021-03-30 | 2022-03-17 | アシルCoA化合物還元活性を有する組換えポリペプチド |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117083388A true CN117083388A (zh) | 2023-11-17 |
Family
ID=83456173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202280024848.0A Withdrawn CN117083388A (zh) | 2021-03-30 | 2022-03-17 | 具有酰基CoA化合物还原活性的重组多肽 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240158764A1 (https=) |
| EP (1) | EP4317438A1 (https=) |
| JP (1) | JPWO2022209994A1 (https=) |
| KR (1) | KR20230162685A (https=) |
| CN (1) | CN117083388A (https=) |
| WO (1) | WO2022209994A1 (https=) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009224087B2 (en) | 2008-03-11 | 2015-04-16 | Genomatica, Inc. | Adipate ester or thioester synthesis |
| MY153590A (en) * | 2008-12-12 | 2015-02-26 | Celexion Llc | Biological synthesis of difunctional alkanes from alpha ketoacids |
| WO2010126670A2 (en) * | 2009-03-27 | 2010-11-04 | Gojo Industries, Inc. | Compositions and methods for screening and using compounds antagonizing spore-surface interactions |
| EP2427544B1 (en) | 2009-05-07 | 2019-07-17 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid |
| WO2010141920A2 (en) | 2009-06-04 | 2010-12-09 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol and related methods |
| JP5930594B2 (ja) | 2011-03-14 | 2016-06-08 | 三菱化学株式会社 | 精製ペンタメチレンジアミンの製造方法及びポリアミド樹脂の製造方法 |
| EP2746400A1 (de) | 2012-12-21 | 2014-06-25 | Evonik Industries AG | Herstellung von Aminen und Diaminen aus einer Carbonsäure oder Dicarbonsäure oder eines Monoesters davon |
| WO2015042201A2 (en) | 2013-09-17 | 2015-03-26 | Zymochem Inc. | A high yield route for the production of compounds from renewable sources |
| WO2015085271A1 (en) | 2013-12-05 | 2015-06-11 | REG Life Sciences, LLC | Microbial production of fatty amines |
| WO2016077800A1 (en) | 2014-11-14 | 2016-05-19 | Invista North America S.á.r.l. | Methods and materials for producing 6-carbon monomers |
| CA3297132A1 (en) * | 2014-12-23 | 2026-03-02 | Genomatica, Inc. | Method of producing & processing diamines |
| WO2019159831A1 (ja) | 2018-02-15 | 2019-08-22 | 国立大学法人神戸大学 | 組換え宿主細胞及びd-ブタントリオールの新規製造方法 |
-
2022
- 2022-03-17 EP EP22780213.9A patent/EP4317438A1/en not_active Withdrawn
- 2022-03-17 CN CN202280024848.0A patent/CN117083388A/zh not_active Withdrawn
- 2022-03-17 KR KR1020237037160A patent/KR20230162685A/ko active Pending
- 2022-03-17 US US18/284,538 patent/US20240158764A1/en active Pending
- 2022-03-17 JP JP2023510962A patent/JPWO2022209994A1/ja active Pending
- 2022-03-17 WO PCT/JP2022/012463 patent/WO2022209994A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR20230162685A (ko) | 2023-11-28 |
| US20240158764A1 (en) | 2024-05-16 |
| EP4317438A1 (en) | 2024-02-07 |
| JPWO2022209994A1 (https=) | 2022-10-06 |
| WO2022209994A1 (ja) | 2022-10-06 |
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| Date | Code | Title | Description |
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| PB01 | Publication | ||
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| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20231117 |
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| WW01 | Invention patent application withdrawn after publication |