CN117062626A - 用于治疗睡眠呼吸暂停的方法和组合物 - Google Patents
用于治疗睡眠呼吸暂停的方法和组合物 Download PDFInfo
- Publication number
- CN117062626A CN117062626A CN202280024023.9A CN202280024023A CN117062626A CN 117062626 A CN117062626 A CN 117062626A CN 202280024023 A CN202280024023 A CN 202280024023A CN 117062626 A CN117062626 A CN 117062626A
- Authority
- CN
- China
- Prior art keywords
- pharmaceutically acceptable
- composition
- acceptable salt
- nri
- oxybutynin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163165342P | 2021-03-24 | 2021-03-24 | |
| US63/165,342 | 2021-03-24 | ||
| PCT/US2022/021462 WO2022204228A1 (en) | 2021-03-24 | 2022-03-23 | Methods and compositions for treating sleep apnea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117062626A true CN117062626A (zh) | 2023-11-14 |
Family
ID=81388916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202280024023.9A Pending CN117062626A (zh) | 2021-03-24 | 2022-03-23 | 用于治疗睡眠呼吸暂停的方法和组合物 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20240173337A1 (https=) |
| EP (1) | EP4313153A1 (https=) |
| JP (1) | JP2024511091A (https=) |
| KR (1) | KR20230159462A (https=) |
| CN (1) | CN117062626A (https=) |
| AU (1) | AU2022245235A1 (https=) |
| BR (1) | BR112023019256A2 (https=) |
| CA (1) | CA3212035A1 (https=) |
| CL (1) | CL2023002824A1 (https=) |
| CO (1) | CO2023012587A2 (https=) |
| CR (1) | CR20230457A (https=) |
| GE (1) | GEAP202416361A (https=) |
| IL (1) | IL307186A (https=) |
| MX (1) | MX2023011213A (https=) |
| WO (1) | WO2022204228A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119789855A (zh) * | 2022-09-02 | 2025-04-08 | 爱普宁公司(特拉华) | 治疗睡眠呼吸暂停的方法和组合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3746126B1 (en) * | 2018-01-30 | 2024-07-31 | Apnimed, Inc. (Delaware) | Methods and compositions for treating sleep apnea or simple snoring |
| EP4635514A3 (en) * | 2019-02-08 | 2025-12-24 | The Brigham & Women's Hospital, Inc. | Methods and compositions for treating sleep apnea |
| JP2023520455A (ja) * | 2020-04-02 | 2023-05-17 | アプニメッド，インコーポレイテッド（デラウェア） | 睡眠時無呼吸を治療するための方法および組成物 |
-
2022
- 2022-03-23 GE GEAP202416361A patent/GEAP202416361A/en unknown
- 2022-03-23 CR CR20230457A patent/CR20230457A/es unknown
- 2022-03-23 CA CA3212035A patent/CA3212035A1/en active Pending
- 2022-03-23 EP EP22719398.4A patent/EP4313153A1/en active Pending
- 2022-03-23 CN CN202280024023.9A patent/CN117062626A/zh active Pending
- 2022-03-23 BR BR112023019256A patent/BR112023019256A2/pt unknown
- 2022-03-23 KR KR1020237034335A patent/KR20230159462A/ko active Pending
- 2022-03-23 US US18/283,303 patent/US20240173337A1/en active Pending
- 2022-03-23 AU AU2022245235A patent/AU2022245235A1/en active Pending
- 2022-03-23 IL IL307186A patent/IL307186A/en unknown
- 2022-03-23 WO PCT/US2022/021462 patent/WO2022204228A1/en not_active Ceased
- 2022-03-23 MX MX2023011213A patent/MX2023011213A/es unknown
- 2022-03-23 JP JP2023558248A patent/JP2024511091A/ja active Pending
-
2023
- 2023-09-22 CL CL2023002824A patent/CL2023002824A1/es unknown
- 2023-09-22 CO CONC2023/0012587A patent/CO2023012587A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112023019256A2 (pt) | 2023-10-17 |
| CA3212035A1 (en) | 2022-09-29 |
| WO2022204228A1 (en) | 2022-09-29 |
| KR20230159462A (ko) | 2023-11-21 |
| JP2024511091A (ja) | 2024-03-12 |
| CR20230457A (es) | 2024-02-19 |
| CO2023012587A2 (es) | 2023-10-19 |
| MX2023011213A (es) | 2023-10-02 |
| AU2022245235A1 (en) | 2023-10-12 |
| EP4313153A1 (en) | 2024-02-07 |
| GEAP202416361A (en) | 2024-04-25 |
| US20240173337A1 (en) | 2024-05-30 |
| CL2023002824A1 (es) | 2024-01-26 |
| IL307186A (en) | 2023-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |