CO2023012587A2 - Métodos y composiciones para tratar la apnea del sueño - Google Patents

Métodos y composiciones para tratar la apnea del sueño

Info

Publication number
CO2023012587A2
CO2023012587A2 CONC2023/0012587A CO2023012587A CO2023012587A2 CO 2023012587 A2 CO2023012587 A2 CO 2023012587A2 CO 2023012587 A CO2023012587 A CO 2023012587A CO 2023012587 A2 CO2023012587 A2 CO 2023012587A2
Authority
CO
Colombia
Prior art keywords
methods
sleep apnea
compositions
treat sleep
antagonist
Prior art date
Application number
CONC2023/0012587A
Other languages
English (en)
Inventor
Lawrence G Miller
Luigi Taranto-Montemurro
Ronald Farkas
Original Assignee
Apnimed Inc Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apnimed Inc Delaware filed Critical Apnimed Inc Delaware
Publication of CO2023012587A2 publication Critical patent/CO2023012587A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

En la presente se describen composiciones farmacéuticas que comprenden un inhibidor de la recaptación de norepinefrina (NRI) y un antagonista de mineralocorticoides y, opcionalmente, un antagonista del receptor muscarínico (MRA) y métodos para tratar la apnea del sueño.
CONC2023/0012587A 2021-03-24 2023-09-22 Métodos y composiciones para tratar la apnea del sueño CO2023012587A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163165342P 2021-03-24 2021-03-24
PCT/US2022/021462 WO2022204228A1 (en) 2021-03-24 2022-03-23 Methods and compositions for treating sleep apnea

Publications (1)

Publication Number Publication Date
CO2023012587A2 true CO2023012587A2 (es) 2023-10-19

Family

ID=81388916

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2023/0012587A CO2023012587A2 (es) 2021-03-24 2023-09-22 Métodos y composiciones para tratar la apnea del sueño

Country Status (14)

Country Link
US (1) US20240173337A1 (es)
EP (1) EP4313153A1 (es)
JP (1) JP2024511091A (es)
KR (1) KR20230159462A (es)
CN (1) CN117062626A (es)
AU (1) AU2022245235A1 (es)
BR (1) BR112023019256A2 (es)
CA (1) CA3212035A1 (es)
CL (1) CL2023002824A1 (es)
CO (1) CO2023012587A2 (es)
CR (1) CR20230457A (es)
IL (1) IL307186A (es)
MX (1) MX2023011213A (es)
WO (1) WO2022204228A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024049885A1 (en) * 2022-09-02 2024-03-07 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202007226UA (en) * 2018-01-30 2020-08-28 Apnimed Inc Delaware Methods and compositions for treating sleep apnea
EA202192202A1 (ru) * 2019-02-08 2021-11-03 Дзе Брихэм Энд Уимен'З Хоспитал, Инк. Способы и композиции для лечения синдрома обструктивного апноэ, возникающего во сне
WO2021202906A1 (en) * 2020-04-02 2021-10-07 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea

Also Published As

Publication number Publication date
JP2024511091A (ja) 2024-03-12
KR20230159462A (ko) 2023-11-21
WO2022204228A1 (en) 2022-09-29
MX2023011213A (es) 2023-10-02
CA3212035A1 (en) 2022-09-29
CN117062626A (zh) 2023-11-14
AU2022245235A1 (en) 2023-10-12
EP4313153A1 (en) 2024-02-07
IL307186A (en) 2023-11-01
US20240173337A1 (en) 2024-05-30
BR112023019256A2 (pt) 2023-10-17
CR20230457A (es) 2024-02-19
CL2023002824A1 (es) 2024-01-26

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