CA3212035A1 - Methods and compositions for treating sleep apnea - Google Patents

Methods and compositions for treating sleep apnea Download PDF

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Publication number
CA3212035A1
CA3212035A1 CA3212035A CA3212035A CA3212035A1 CA 3212035 A1 CA3212035 A1 CA 3212035A1 CA 3212035 A CA3212035 A CA 3212035A CA 3212035 A CA3212035 A CA 3212035A CA 3212035 A1 CA3212035 A1 CA 3212035A1
Authority
CA
Canada
Prior art keywords
pharmaceutically acceptable
acceptable salt
composition
oxybutynin
nri
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3212035A
Other languages
English (en)
French (fr)
Inventor
Lawrence G. Miller
Luigi TARANTO-MONTEMURRO
Ronald FARKAS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apnimed Inc
Original Assignee
Apnimed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apnimed Inc filed Critical Apnimed Inc
Publication of CA3212035A1 publication Critical patent/CA3212035A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA3212035A 2021-03-24 2022-03-23 Methods and compositions for treating sleep apnea Pending CA3212035A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163165342P 2021-03-24 2021-03-24
US63/165,342 2021-03-24
PCT/US2022/021462 WO2022204228A1 (en) 2021-03-24 2022-03-23 Methods and compositions for treating sleep apnea

Publications (1)

Publication Number Publication Date
CA3212035A1 true CA3212035A1 (en) 2022-09-29

Family

ID=81388916

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3212035A Pending CA3212035A1 (en) 2021-03-24 2022-03-23 Methods and compositions for treating sleep apnea

Country Status (15)

Country Link
US (1) US20240173337A1 (https=)
EP (1) EP4313153A1 (https=)
JP (1) JP2024511091A (https=)
KR (1) KR20230159462A (https=)
CN (1) CN117062626A (https=)
AU (1) AU2022245235A1 (https=)
BR (1) BR112023019256A2 (https=)
CA (1) CA3212035A1 (https=)
CL (1) CL2023002824A1 (https=)
CO (1) CO2023012587A2 (https=)
CR (1) CR20230457A (https=)
GE (1) GEAP202416361A (https=)
IL (1) IL307186A (https=)
MX (1) MX2023011213A (https=)
WO (1) WO2022204228A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119789855A (zh) * 2022-09-02 2025-04-08 爱普宁公司(特拉华) 治疗睡眠呼吸暂停的方法和组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3746126B1 (en) * 2018-01-30 2024-07-31 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea or simple snoring
EP4635514A3 (en) * 2019-02-08 2025-12-24 The Brigham & Women's Hospital, Inc. Methods and compositions for treating sleep apnea
JP2023520455A (ja) * 2020-04-02 2023-05-17 アプニメッド,インコーポレイテッド(デラウェア) 睡眠時無呼吸を治療するための方法および組成物

Also Published As

Publication number Publication date
BR112023019256A2 (pt) 2023-10-17
WO2022204228A1 (en) 2022-09-29
KR20230159462A (ko) 2023-11-21
JP2024511091A (ja) 2024-03-12
CR20230457A (es) 2024-02-19
CN117062626A (zh) 2023-11-14
CO2023012587A2 (es) 2023-10-19
MX2023011213A (es) 2023-10-02
AU2022245235A1 (en) 2023-10-12
EP4313153A1 (en) 2024-02-07
GEAP202416361A (en) 2024-04-25
US20240173337A1 (en) 2024-05-30
CL2023002824A1 (es) 2024-01-26
IL307186A (en) 2023-11-01

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