CN117018130A - Traditional Chinese medicine composition for treating pelvic inflammation and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating pelvic inflammation and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicine compositions, and provides a traditional Chinese medicine composition for treating pelvic inflammation and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: the fourteen traditional Chinese medicines of sargentgloryvine stem, herba patriniae, dandelion, honeysuckle, weeping forsythiae capsule, red sage root, red paeony root, coix seed, glabrous greenbrier rhizome, moutan bark, amur corktree bark, rhubarb and liquorice and szechwan chinaberry fruit are prepared into an oral medicinal preparation by a series of preparation processes, wherein the oral medicinal preparation comprises tablets, pills, granules, capsules and liquid; the traditional Chinese medicine composition has remarkable effects of clearing heat and detoxicating, promoting blood circulation and removing blood stasis, calming and relieving pain and regulating qi and excreting dampness, has obvious effect of treating pelvic inflammatory disease and small toxic and side effects, can be used together with other proper medicinal materials by dialectical addition and subtraction, and has better effect.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for treating pelvic inflammation and a preparation method thereof.
Background
Pelvic Inflammatory Disease (PID), which is a disease of the upper genital tract of females and the surrounding tissues (uterus, fallopian tube, ovarian parauterine tissue and pelvic peritoneum), often involves adjacent tissues, and can be classified into acute pelvic inflammatory disease and chronic pelvic inflammatory disease according to the pathogenesis and clinical manifestations.
The common causes of pelvic inflammatory disease are infection after postpartum or abortion, infection after intrauterine operation, direct spreading of menstrual hygiene and inflammation of adjacent organs, and other causes; the main clinical manifestations of the acute pelvic inflammatory disease are lower abdominal pain, fever, increased vaginal secretion, persistent abdominal pain, and serious activity or sexual intercourse, if the illness is serious, chills, high fever, headache and inappetence can occur, the further development of the acute pelvic inflammatory disease can cause diffuse peritonitis, septicemia and infectious shock, and serious people can endanger lives; the chronic pelvic inflammatory disease is mainly caused by incomplete treatment of acute pelvic inflammatory disease or poor constitution of patients and prolonged disease course, and symptoms of the chronic pelvic inflammatory disease are lower abdomen distention, pain and lumbosacral part ache, which are often aggravated after fatigue and intercourse and before and after menstruation, often can be healed after long time and repeatedly attack, resulting in infertility and tubal pregnancy, and seriously affecting the health of women.
At present, the treatment of pelvic inflammatory disease is mainly carried out by antibiotic treatment in Western medicine, generally broad-spectrum antibiotics or combined medicines are selected, and the antibiotics can clear pathogens and improve symptoms and signs, and although the treatment effect is good, normal flora can be easily destroyed when the antibiotics are used, once the antibiotics recur again, drug resistance can be generated, and the treatment is affected; in recent years, as the research of traditional Chinese medicine in treating pelvic inflammatory disease achieves a larger result, more and more patients choose traditional Chinese medicine treatment; the traditional Chinese medicine for treating pelvic inflammatory disease contains more than twenty medicinal materials, even more than thirty medicinal materials, and has more medicinal materials, more complicated preparation, increased medicine cost and no contribution to popularization and effective quality control in the market.
Therefore, a traditional Chinese medicine composition for treating pelvic inflammation and a preparation method thereof are provided by the person skilled in the art to solve the problems provided by the background art.
Disclosure of Invention
In order to solve the technical problems, the invention provides a traditional Chinese medicine composition for treating pelvic inflammation and a preparation method thereof, and aims to solve the problems of complex preparation, high medicine cost and the like in the prior art.
In order to achieve the above purpose, the present invention provides the following technical solutions:
the traditional Chinese medicine composition for treating pelvic inflammation and the preparation method thereof are provided, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 20-50g of sargentgloryvine stem, 10-35g of herba patriniae, 10-30g of dandelion, 10-25g of honeysuckle, 10-25g of fructus forsythiae, 5-25g of red sage root, 5-25g of red paeony root, 5-20g of coix seed, 5-20g of glabrous greenbrier rhizome, 8-18g of tree peony bark, 6-18g of amur corktree bark, 5-12g of rhubarb, 5-10g of liquorice and 5-9g of szechwan chinaberry fruit.
Preferably, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30g of sargentgloryvine stem, 20g of herba patriniae, 20g of dandelion, 20g of honeysuckle, 20g of fructus forsythiae, 15g of red sage root, 15g of red paeony root, 15g of coix seed, 15g of glabrous greenbrier rhizome, 12g of tree peony bark, 12g of amur corktree bark, 10g of rhubarb, 10g of liquorice and 9g of szechwan chinaberry fruit.
Preferably, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 35g of sargentgloryvine stem, 20g of herba patriniae, 15g of dandelion, 17g of honeysuckle, 17g of fructus forsythiae, 12g of red sage root, 12g of red paeony root, 10g of coix seed, 12g of glabrous greenbrier rhizome, 10g of tree peony bark, 10g of amur corktree bark, 8g of rhubarb, 8g of liquorice and 6g of szechwan chinaberry fruit.
Preferably, the Chinese medicinal composition is an oral medicinal preparation, wherein the oral medicinal preparation comprises tablets, pills, granules, capsules and liquid.
Preferably, the method comprises the following steps:
s1: taking a proper amount of sargentgloryvine stem, herba patriniae, dandelion, honeysuckle and weeping forsythiae capsule, pouring the sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule into a pulverizer for pulverization, sieving the pulverized sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule, adding 60-70% ethanol for extraction for two to four times, wherein the amount of the added ethanol is 5 times of the weight of the medicinal materials, soaking the sieved medicinal material powder in ethanol for 1-2 hours, refluxing the medicinal material powder for extraction for 1-3 hours, filtering the medicinal material powder, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking a proper amount of salvia miltiorrhiza, coix seed, moutan bark, phellodendron bark and rheum officinale in a formula, crushing and sieving, adding ethanol which is 5 times of the weight of the medicinal materials and is 60-70% of the weight of the medicinal materials for extraction for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating the ethanol into a concentrated solution to obtain a composition II;
s3: decocting radix Paeoniae Rubra, rhizoma Smilacis Glabrae, fructus Toosendan and Glycyrrhrizae radix with 5 times of water for 1-2 hr for twice, filtering the decoction, and concentrating to obtain composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating the thick paste with the relative density of 1.25-1.40 again after mixing, and drying at high temperature to obtain a dry paste;
s5: pulverizing the dry paste, adding appropriate amount of sucrose, mixing, dry pressing to obtain granule, and making into tablet, pill, granule and capsule by various processes.
Preferably, the method comprises the following steps
S1: taking a proper amount of sargentgloryvine stem, herba patriniae, dandelion, honeysuckle and weeping forsythiae capsule, pouring the sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule into a pulverizer for pulverization, sieving the pulverized sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule, adding 60-70% ethanol for extraction for two to four times, wherein the amount of the added ethanol is 5 times of the weight of the medicinal materials, soaking the sieved medicinal material powder in ethanol for 1-2 hours, refluxing the medicinal material powder for extraction for 1-3 hours, filtering the medicinal material powder, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking a proper amount of salvia miltiorrhiza, coix seed, moutan bark, phellodendron bark and rheum officinale in a formula, crushing and sieving, adding ethanol which is 5 times of the weight of the medicinal materials and is 60-70% of the weight of the medicinal materials for extraction for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating the ethanol into a concentrated solution to obtain a composition II;
s3: decocting radix Paeoniae Rubra, rhizoma Smilacis Glabrae, fructus Toosendan and Glycyrrhrizae radix with 5 times of water for 1-2 hr for twice, filtering the decoction, and concentrating to obtain composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating again to obtain a concentrated solution, adding a proper amount of sodium benzoate and water, and uniformly mixing to obtain the oral liquid.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention can clear away heat and toxic materials, dissipate blood stasis and relieve pain through bitter and cold medicinal materials such as sargentgloryvine stem, herba patriniae and the like; semen Coicis and rhizoma Smilacis Glabrae for clearing away heat and toxic materials, invigorating spleen, and removing dampness; radix Salviae Miltiorrhizae, cortex moutan, etc., and is used for refreshing and cooling blood, promoting blood circulation, dispelling blood stasis, and clearing away heat; rhubarb and phellodendron bark are used for clearing toxin of damp-heat stasis in lower-jiao pelvic cavity; fructus Toosendan is used for relieving liver and regulating qi; the liquorice is used for purging fire and detoxifying, and in the preparation steps, different medicine demands are conveniently provided for patients through crushing, extraction, dry agent preparation and liquid preparation, the types and the number of medicinal materials in the formula are relatively simple, the preparation process is simplified, the medicine cost is reduced, and the preparation method is favorable for market popularization.
Detailed Description
The technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Embodiment one:
the invention provides a traditional Chinese medicine composition for treating pelvic inflammation and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 20-50g of sargentgloryvine stem, 10-35g of herba patriniae, 10-30g of dandelion, 10-25g of honeysuckle, 10-25g of fructus forsythiae, 5-25g of red sage root, 5-25g of red paeony root, 5-20g of coix seed, 5-20g of glabrous greenbrier rhizome, 8-18g of tree peony bark, 6-18g of amur corktree bark, 5-12g of rhubarb, 5-10g of liquorice and 5-9g of szechwan chinaberry fruit.
The medicinal materials with the components are divided into two groups of different weights, so that the effect of the different weights of each medicinal material on the medicinal effect can be conveniently checked;
first, the weight of each medicinal material is: 30g of sargentgloryvine stem, 20g of herba patriniae, 20g of dandelion, 20g of honeysuckle, 20g of fructus forsythiae, 15g of red sage root, 15g of red paeony root, 15g of coix seed, 15g of glabrous greenbrier rhizome, 12g of tree peony bark, 12g of amur corktree bark, 10g of rhubarb, 10g of liquorice and 9g of szechwan chinaberry fruit.
Second, the weight of each medicinal material is: 35g of sargentgloryvine stem, 20g of herba patriniae, 15g of dandelion, 17g of honeysuckle, 17g of fructus forsythiae, 12g of red sage root, 12g of red paeony root, 10g of coix seed, 12g of glabrous greenbrier rhizome, 10g of tree peony bark, 10g of amur corktree bark, 8g of rhubarb, 8g of liquorice and 6g of szechwan chinaberry fruit.
Specifically, the traditional Chinese medicine composition is an oral pharmaceutical preparation, and comprises tablets, pills, granules, capsules and liquid.
Using the first formulation as an example, the second formulation is configured identically to the first formulation;
specifically, the method comprises the following steps:
s1: taking 30g of sargentgloryvine stem, 20g of herba patriniae, 20g of dandelion, 20g of honeysuckle and 20g of fructus forsythiae of a proper amount of formula, pouring into a pulverizer for pulverization, simply sieving after pulverization, adding 60-70% ethanol for extraction for two to four times, wherein the amount of added ethanol is 550g which is 5 times of the weight of the medicinal materials, firstly soaking the sieved medicinal material powder in ethanol for 1-2 hours, then carrying out reflux extraction for 1-3 hours, filtering, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking 15g of red sage root, 15g of coix seed, 12g of tree peony bark, 12g of amur corktree bark and 10g of rhubarb with proper formulation, crushing and sieving, adding 60-70% ethanol which is 5 times of the weight of the medicinal materials into 320g, extracting for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating into a concentrated solution to obtain a composition II;
s3: taking 15g of red paeony root, 15g of glabrous greenbrier rhizome, 9g of szechwan chinaberry fruit and 10g of liquorice with a proper amount of 245g of water which is 5 times of the medicinal materials, decocting for 1-2 hours for twice, filtering the decocted liquid of the two times, and concentrating the filtered liquid into a concentrated solution to obtain a composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating the thick paste with the relative density of 1.25-1.40 again after mixing, and drying at high temperature to obtain a dry paste;
s5: pulverizing the dry paste, adding appropriate amount of sucrose, mixing, dry pressing to obtain granule, and making into tablet, pill, granule and capsule by various processes.
Specifically, the method comprises the following steps of
S1: taking 30g of sargentgloryvine stem, 20g of herba patriniae, 20g of dandelion, 20g of honeysuckle and 20g of fructus forsythiae of a proper amount of formula, pouring into a pulverizer for pulverization, simply sieving after pulverization, adding 60-70% ethanol for extraction for two to four times, wherein the amount of added ethanol is 550g which is 5 times of the weight of the medicinal materials, firstly soaking the sieved medicinal material powder in ethanol for 1-2 hours, then carrying out reflux extraction for 1-3 hours, filtering, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking 15g of red sage root, 15g of coix seed, 12g of tree peony bark, 12g of amur corktree bark and 10g of rhubarb with proper formulation, crushing and sieving, adding 60-70% ethanol which is 5 times of the weight of the medicinal materials into 320g, extracting for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating into a concentrated solution to obtain a composition II;
s3: taking 15g of red paeony root, 15g of glabrous greenbrier rhizome, 9g of szechwan chinaberry fruit and 10g of liquorice with a proper amount of 245g of water which is 5 times of the medicinal materials, decocting for 1-2 hours for twice, filtering the decocted liquid of the two times, and concentrating the filtered liquid into a concentrated solution to obtain a composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating again to obtain a concentrated solution, adding a proper amount of sodium benzoate and water, and uniformly mixing to obtain the oral liquid.
Embodiment two:
the embodiment is basically the same as the previous embodiment, except that the ginseng, the poria, the bighead atractylodes rhizome and other medicinal materials for strengthening spleen and tonifying qi are added in the step S1 through dialectical addition and subtraction, and are used for patients with spleen qi deficiency;
the preparation method of the oral dry agent is as follows
S1: taking 30g of sargentgloryvine stem, 20g of herba patriniae, 20g of dandelion, 20g of honeysuckle and 20g of weeping forsythiae capsule with a proper amount of formula, adding 5g of ginseng, poria and bighead atractylodes rhizome respectively, pouring into a pulverizer for pulverization, simply sieving, adding 60-70% of ethanol for extraction for two to four times, wherein the amount of the added ethanol is 5 times of the weight of the medicinal materials, firstly soaking the sieved medicinal material powder in ethanol for 1-2 hours, then extracting under reflux for 1-3 hours, filtering, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking 15g of red sage root, 15g of coix seed, 12g of tree peony bark, 12g of amur corktree bark and 10g of rhubarb with proper formulation, crushing and sieving, adding 60-70% ethanol which is 5 times of the weight of the medicinal materials into 320g, extracting for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating into a concentrated solution to obtain a composition II;
s3: taking 15g of red paeony root, 15g of glabrous greenbrier rhizome, 9g of szechwan chinaberry fruit and 10g of liquorice with a proper amount of 245g of water which is 5 times of the medicinal materials, decocting for 1-2 hours for twice, filtering the decocted liquid of the two times, and concentrating the filtered liquid into a concentrated solution to obtain a composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating the thick paste with the relative density of 1.25-1.40 again after mixing, and drying at high temperature to obtain a dry paste;
s5: pulverizing the dry paste, adding appropriate amount of sucrose, mixing, dry pressing to obtain granule, and making into tablet, pill, granule and capsule by various processes.
From the above, it is known that the ginseng, poria and bighead atractylodes rhizome are added to have the effects of strengthening spleen and tonifying qi.
The preparation method of the oral liquid is as follows
S1: taking 30g of sargentgloryvine stem, 20g of herba patriniae, 20g of dandelion, 20g of honeysuckle and 20g of weeping forsythiae capsule with a proper amount of formula, adding 5g of ginseng, poria and bighead atractylodes rhizome respectively, pouring into a pulverizer for pulverization, simply sieving, adding 60-70% of ethanol for extraction for two to four times, wherein the amount of the added ethanol is 5 times of the weight of the medicinal materials, firstly soaking the sieved medicinal material powder in ethanol for 1-2 hours, then extracting under reflux for 1-3 hours, filtering, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking 15g of red sage root, 15g of coix seed, 12g of tree peony bark, 12g of amur corktree bark and 10g of rhubarb with proper formulation, crushing and sieving, adding 60-70% ethanol which is 5 times of the weight of the medicinal materials into 320g, extracting for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating into a concentrated solution to obtain a composition II;
s3: taking 15g of red paeony root, 15g of glabrous greenbrier rhizome, 9g of szechwan chinaberry fruit and 10g of liquorice with a proper amount of 245g of water which is 5 times of the medicinal materials, decocting for 1-2 hours for twice, filtering the decocted liquid of the two times, and concentrating the filtered liquid into a concentrated solution to obtain a composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating again to obtain a concentrated solution, adding a proper amount of sodium benzoate and water, and uniformly mixing to obtain the oral liquid.
Embodiment III:
this embodiment is basically the same as the previous embodiment except that by dialectical addition and subtraction, carapax Trionycis and Eupolyphaga Seu Steleophaga are added as appropriate in step S1 for patients with agglomeration symptoms in abdomen and long-lasting.
From the above, medical staff can select different formulas to treat according to symptoms of patients; the medicinal materials with bitter and cold properties such as sargentgloryvine stem, herba patriniae and the like can clear away heat and toxic materials, dissipate blood stasis and relieve pain; semen Coicis and rhizoma Smilacis Glabrae for clearing away heat and toxic materials, invigorating spleen, and removing dampness; radix Salviae Miltiorrhizae, cortex moutan, etc., and is used for refreshing and cooling blood, promoting blood circulation, dispelling blood stasis, and clearing away heat; rhubarb and phellodendron bark are used for clearing toxin of damp-heat stasis in lower-jiao pelvic cavity; fructus Toosendan is used for relieving liver and regulating qi; the liquorice is used for purging fire and detoxifying, and when the liquorice is used, other medicinal materials are added in proper amount in the preparation step through dialectical addition and subtraction, and the medicinal materials are prepared into oral dry preparations and oral liquid through crushing and extraction, so that different medicine requirements are conveniently provided for patients, the types and the quantity of the medicinal materials in the formula are relatively simple, the preparation process is simplified, the medicine cost is reduced, and the liquorice is beneficial to market popularization; the traditional Chinese medicine composition has remarkable effects of clearing heat and detoxicating, promoting blood circulation and removing blood stasis, calming and relieving pain and regulating qi and excreting dampness, and has better effect of treating pelvic inflammation.
While embodiments of the present invention have been shown and described above for purposes of illustration and description, it will be understood that the above embodiments are illustrative and not to be construed as limiting the invention, and that variations, modifications, alternatives, and variations may be made to the above embodiments by one of ordinary skill in the art within the scope of the invention.
Claims (6)
1. A traditional Chinese medicine composition for treating pelvic inflammation is characterized in that: the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-50g of sargentgloryvine stem, 10-35g of herba patriniae, 10-30g of dandelion, 10-25g of honeysuckle, 10-25g of fructus forsythiae, 5-25g of red sage root, 5-25g of red paeony root, 5-20g of coix seed, 5-20g of glabrous greenbrier rhizome, 8-18g of tree peony bark, 6-18g of amur corktree bark, 5-12g of rhubarb, 5-10g of liquorice and 5-9g of szechwan chinaberry fruit.
2. The traditional Chinese medicine composition for treating pelvic inflammation according to claim 1, wherein: the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30g of sargentgloryvine stem, 20g of herba patriniae, 20g of dandelion, 20g of honeysuckle, 20g of fructus forsythiae, 15g of red sage root, 15g of red paeony root, 15g of coix seed, 15g of glabrous greenbrier rhizome, 12g of tree peony bark, 12g of amur corktree bark, 10g of rhubarb, 10g of liquorice and 9g of szechwan chinaberry fruit.
3. The traditional Chinese medicine composition for treating pelvic inflammation according to claim 1, wherein: the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 35g of sargentgloryvine stem, 20g of herba patriniae, 15g of dandelion, 17g of honeysuckle, 17g of fructus forsythiae, 12g of red sage root, 12g of red paeony root, 10g of coix seed, 12g of glabrous greenbrier rhizome, 10g of tree peony bark, 10g of amur corktree bark, 8g of rhubarb, 8g of liquorice and 6g of szechwan chinaberry fruit.
4. The traditional Chinese medicine composition for treating pelvic inflammation according to claim 1, wherein: the traditional Chinese medicine composition is an oral pharmaceutical preparation, and comprises tablets, pills, granules, capsules and liquid.
5. The method for preparing a traditional Chinese medicine composition for treating pelvic inflammation according to claim 4, wherein the method comprises the following steps: comprises the following steps:
s1: taking a proper amount of sargentgloryvine stem, herba patriniae, dandelion, honeysuckle and weeping forsythiae capsule, pouring the sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule into a pulverizer for pulverization, sieving the pulverized sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule, adding 60-70% ethanol for extraction for two to four times, wherein the amount of the added ethanol is 5 times of the weight of the medicinal materials, soaking the sieved medicinal material powder in ethanol for 1-2 hours, refluxing the medicinal material powder for extraction for 1-3 hours, filtering the medicinal material powder, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking a proper amount of salvia miltiorrhiza, coix seed, moutan bark, phellodendron bark and rheum officinale in a formula, crushing and sieving, adding ethanol which is 5 times of the weight of the medicinal materials and is 60-70% of the weight of the medicinal materials for extraction for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating the ethanol into a concentrated solution to obtain a composition II;
s3: decocting radix Paeoniae Rubra, rhizoma Smilacis Glabrae, fructus Toosendan and Glycyrrhrizae radix with 5 times of water for 1-2 hr for twice, filtering the decoction, and concentrating to obtain composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating the thick paste with the relative density of 1.25-1.40 again after mixing, and drying at high temperature to obtain a dry paste;
s5: pulverizing the dry paste, adding appropriate amount of sucrose, mixing, dry pressing to obtain granule, and making into tablet, pill, granule and capsule by various processes.
6. The method for preparing the traditional Chinese medicine composition for treating pelvic inflammation according to claim 1, which is characterized in that: comprises the following steps
S1: taking a proper amount of sargentgloryvine stem, herba patriniae, dandelion, honeysuckle and weeping forsythiae capsule, pouring the sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule into a pulverizer for pulverization, sieving the pulverized sargentgloryvine stem, the herba patriniae, the dandelion, the honeysuckle and the weeping forsythia capsule, adding 60-70% ethanol for extraction for two to four times, wherein the amount of the added ethanol is 5 times of the weight of the medicinal materials, soaking the sieved medicinal material powder in ethanol for 1-2 hours, refluxing the medicinal material powder for extraction for 1-3 hours, filtering the medicinal material powder, and collecting filtrate; adding 5 times of 60-70% ethanol into the rest residues for secondary extraction for 1-2 hours, and reducing the extraction time similar to the above steps for the third time; then combining the multiple extracted filtrates, recovering ethanol, and concentrating to obtain a concentrated solution to obtain a composition I;
s2: taking a proper amount of salvia miltiorrhiza, coix seed, moutan bark, phellodendron bark and rheum officinale in a formula, crushing and sieving, adding ethanol which is 5 times of the weight of the medicinal materials and is 60-70% of the weight of the medicinal materials for extraction for two to four times, combining the filtrates obtained by the multiple extraction in the same step S1, recovering the ethanol, and concentrating the ethanol into a concentrated solution to obtain a composition II;
s3: decocting radix Paeoniae Rubra, rhizoma Smilacis Glabrae, fructus Toosendan and Glycyrrhrizae radix with 5 times of water for 1-2 hr for twice, filtering the decoction, and concentrating to obtain composition III;
s4: fully mixing the first composition, the second composition and the third composition, concentrating again to obtain a concentrated solution, adding a proper amount of sodium benzoate and water, and uniformly mixing to obtain the oral liquid.
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| 刘素哲: "盆腔清解汤加味治疗急性盆腔炎32例", 河南中医学院学报, vol. 18, no. 04, 20 July 2003 (2003-07-20), pages 69 - 70 * |
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