CN116998496A - 湿巾消毒液及其制备方法、消毒湿巾 - Google Patents
湿巾消毒液及其制备方法、消毒湿巾 Download PDFInfo
- Publication number
- CN116998496A CN116998496A CN202310921840.0A CN202310921840A CN116998496A CN 116998496 A CN116998496 A CN 116998496A CN 202310921840 A CN202310921840 A CN 202310921840A CN 116998496 A CN116998496 A CN 116998496A
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- China
- Prior art keywords
- disinfectant
- wet
- wet wipe
- wet tissue
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000645 desinfectant Substances 0.000 title claims abstract description 163
- 238000002360 preparation method Methods 0.000 title abstract description 8
- 239000003463 adsorbent Substances 0.000 claims abstract description 31
- -1 iron ions Chemical class 0.000 claims abstract description 28
- 239000007788 liquid Substances 0.000 claims description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 36
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical group [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 24
- 239000008213 purified water Substances 0.000 claims description 22
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 21
- 229960000686 benzalkonium chloride Drugs 0.000 claims description 15
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims description 15
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 15
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 15
- 239000004094 surface-active agent Substances 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 12
- 229920000223 polyglycerol Polymers 0.000 claims description 12
- 239000001509 sodium citrate Substances 0.000 claims description 10
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 10
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 claims description 9
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 9
- 229960002233 benzalkonium bromide Drugs 0.000 claims description 9
- KHSLHYAUZSPBIU-UHFFFAOYSA-M benzododecinium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 KHSLHYAUZSPBIU-UHFFFAOYSA-M 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 9
- FDGBQHCDMSYZRC-UHFFFAOYSA-N 2-hydroxy-2-oxo-1,3,2$l^{5}-dioxaphosphinan-4-amine Chemical compound NC1CCOP(O)(=O)O1 FDGBQHCDMSYZRC-UHFFFAOYSA-N 0.000 claims description 8
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 claims description 8
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims description 8
- 235000019799 monosodium phosphate Nutrition 0.000 claims description 8
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims description 8
- 229920001213 Polysorbate 20 Polymers 0.000 claims description 7
- 229930182478 glucoside Natural products 0.000 claims description 7
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims description 7
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims description 7
- DZCAZXAJPZCSCU-UHFFFAOYSA-K sodium nitrilotriacetate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CC([O-])=O DZCAZXAJPZCSCU-UHFFFAOYSA-K 0.000 claims description 7
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- SOYKEARSMXGVTM-UHFFFAOYSA-N chlorphenamine Chemical compound C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 SOYKEARSMXGVTM-UHFFFAOYSA-N 0.000 claims description 6
- 229960003291 chlorphenamine Drugs 0.000 claims description 6
- MTZQAGJQAFMTAQ-UHFFFAOYSA-N ethyl benzoate Chemical compound CCOC(=O)C1=CC=CC=C1 MTZQAGJQAFMTAQ-UHFFFAOYSA-N 0.000 claims description 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 6
- QPJVMBTYPHYUOC-UHFFFAOYSA-N methyl benzoate Chemical compound COC(=O)C1=CC=CC=C1 QPJVMBTYPHYUOC-UHFFFAOYSA-N 0.000 claims description 6
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 6
- 239000003607 modifier Substances 0.000 claims description 5
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 3
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims description 3
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- JMHWNJGXUIJPKG-UHFFFAOYSA-N CC(=O)O[SiH](CC=C)OC(C)=O Chemical compound CC(=O)O[SiH](CC=C)OC(C)=O JMHWNJGXUIJPKG-UHFFFAOYSA-N 0.000 claims description 3
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 claims description 3
- WJLVQTJZDCGNJN-UHFFFAOYSA-N Chlorhexidine hydrochloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 claims description 3
- RUPBZQFQVRMKDG-UHFFFAOYSA-M Didecyldimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC RUPBZQFQVRMKDG-UHFFFAOYSA-M 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 3
- 229940120146 EDTMP Drugs 0.000 claims description 3
- 229910019142 PO4 Inorganic materials 0.000 claims description 3
- 229920002413 Polyhexanide Polymers 0.000 claims description 3
- DDAQLPYLBPPPRV-UHFFFAOYSA-N [4-(hydroxymethyl)-2-oxo-1,3,2lambda5-dioxaphosphetan-2-yl] dihydrogen phosphate Chemical compound OCC1OP(=O)(OP(O)(O)=O)O1 DDAQLPYLBPPPRV-UHFFFAOYSA-N 0.000 claims description 3
- GIYMJJRYEFFRKQ-UHFFFAOYSA-K [Na+].[Na+].[Na+].CNCC(=O)[O-].CNCC(=O)[O-].CNCC(=O)[O-] Chemical compound [Na+].[Na+].[Na+].CNCC(=O)[O-].CNCC(=O)[O-].CNCC(=O)[O-] GIYMJJRYEFFRKQ-UHFFFAOYSA-K 0.000 claims description 3
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 3
- UDEWPOVQBGFNGE-UHFFFAOYSA-N benzoic acid n-propyl ester Natural products CCCOC(=O)C1=CC=CC=C1 UDEWPOVQBGFNGE-UHFFFAOYSA-N 0.000 claims description 3
- 239000004359 castor oil Substances 0.000 claims description 3
- 235000019438 castor oil Nutrition 0.000 claims description 3
- 229960002798 cetrimide Drugs 0.000 claims description 3
- 229960002152 chlorhexidine acetate Drugs 0.000 claims description 3
- 229960004504 chlorhexidine hydrochloride Drugs 0.000 claims description 3
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 3
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 3
- UMGXUWVIJIQANV-UHFFFAOYSA-M didecyl(dimethyl)azanium;bromide Chemical compound [Br-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC UMGXUWVIJIQANV-UHFFFAOYSA-M 0.000 claims description 3
- 229960004670 didecyldimethylammonium chloride Drugs 0.000 claims description 3
- 229940090960 diethylenetriamine pentamethylene phosphonic acid Drugs 0.000 claims description 3
- APTVNWGLSRAOFJ-UHFFFAOYSA-M dimethyl(dioctyl)azanium;bromide Chemical compound [Br-].CCCCCCCC[N+](C)(C)CCCCCCCC APTVNWGLSRAOFJ-UHFFFAOYSA-M 0.000 claims description 3
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 3
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 3
- DDXLVDQZPFLQMZ-UHFFFAOYSA-M dodecyl(trimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)C DDXLVDQZPFLQMZ-UHFFFAOYSA-M 0.000 claims description 3
- DUYCTCQXNHFCSJ-UHFFFAOYSA-N dtpmp Chemical compound OP(=O)(O)CN(CP(O)(O)=O)CCN(CP(O)(=O)O)CCN(CP(O)(O)=O)CP(O)(O)=O DUYCTCQXNHFCSJ-UHFFFAOYSA-N 0.000 claims description 3
- NFDRPXJGHKJRLJ-UHFFFAOYSA-N edtmp Chemical compound OP(O)(=O)CN(CP(O)(O)=O)CCN(CP(O)(O)=O)CP(O)(O)=O NFDRPXJGHKJRLJ-UHFFFAOYSA-N 0.000 claims description 3
- 150000002191 fatty alcohols Chemical class 0.000 claims description 3
- 125000005456 glyceride group Chemical group 0.000 claims description 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 3
- 239000004310 lactic acid Substances 0.000 claims description 3
- 235000014655 lactic acid Nutrition 0.000 claims description 3
- 239000001630 malic acid Substances 0.000 claims description 3
- 235000011090 malic acid Nutrition 0.000 claims description 3
- 229940095102 methyl benzoate Drugs 0.000 claims description 3
- OLXYLDUSSBULGU-UHFFFAOYSA-N methyl pyridine-4-carboxylate Chemical compound COC(=O)C1=CC=NC=C1 OLXYLDUSSBULGU-UHFFFAOYSA-N 0.000 claims description 3
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 3
- OEIJHBUUFURJLI-UHFFFAOYSA-N octane-1,8-diol Chemical compound OCCCCCCCCO OEIJHBUUFURJLI-UHFFFAOYSA-N 0.000 claims description 3
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 3
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 239000010452 phosphate Substances 0.000 claims description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 3
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 3
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 3
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 claims description 3
- 239000001488 sodium phosphate Substances 0.000 claims description 3
- 229910000162 sodium phosphate Inorganic materials 0.000 claims description 3
- 235000011008 sodium phosphates Nutrition 0.000 claims description 3
- 235000019830 sodium polyphosphate Nutrition 0.000 claims description 3
- 239000001384 succinic acid Substances 0.000 claims description 3
- 150000005846 sugar alcohols Polymers 0.000 claims description 3
- 239000012747 synergistic agent Substances 0.000 claims description 3
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 3
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 1
- 230000000249 desinfective effect Effects 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 39
- 239000004745 nonwoven fabric Substances 0.000 abstract description 25
- 239000000835 fiber Substances 0.000 abstract description 16
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract description 16
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 abstract description 14
- 229910052742 iron Inorganic materials 0.000 abstract description 14
- 229910001425 magnesium ion Inorganic materials 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 13
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract description 12
- 229910001424 calcium ion Inorganic materials 0.000 abstract description 12
- 238000001179 sorption measurement Methods 0.000 abstract description 9
- 230000001954 sterilising effect Effects 0.000 description 30
- 238000003756 stirring Methods 0.000 description 20
- 238000001125 extrusion Methods 0.000 description 17
- 230000000052 comparative effect Effects 0.000 description 16
- 239000000203 mixture Substances 0.000 description 14
- 230000000844 anti-bacterial effect Effects 0.000 description 8
- 230000001105 regulatory effect Effects 0.000 description 8
- 235000011083 sodium citrates Nutrition 0.000 description 8
- 238000004806 packaging method and process Methods 0.000 description 7
- 241000222122 Candida albicans Species 0.000 description 5
- 229940095731 candida albicans Drugs 0.000 description 5
- 235000015165 citric acid Nutrition 0.000 description 5
- MXOAEAUPQDYUQM-QMMMGPOBSA-N (S)-chlorphenesin Chemical compound OC[C@H](O)COC1=CC=C(Cl)C=C1 MXOAEAUPQDYUQM-QMMMGPOBSA-N 0.000 description 3
- 229960003993 chlorphenesin Drugs 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 235000011118 potassium hydroxide Nutrition 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 235000011121 sodium hydroxide Nutrition 0.000 description 2
- 239000003206 sterilizing agent Substances 0.000 description 2
- 235000011044 succinic acid Nutrition 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
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- A—HUMAN NECESSITIES
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- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P3/00—Fungicides
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- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K10/00—Body-drying implements; Toilet paper; Holders therefor
- A47K10/16—Paper towels; Toilet paper; Holders therefor
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
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- A—HUMAN NECESSITIES
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
本发明公开了一种湿巾消毒液及其制备方法、消毒湿巾,在湿巾消毒液浸润无纺布或无尘纸等湿巾本体或载体,湿巾本体或载体对本发明的湿巾消毒液中消毒剂几乎无吸附,其中,抗吸附剂以优异的铁离子、钙离子、镁离子等屏蔽能力,在抗吸附剂与湿巾本体或载体的纤维中铁离子、钙离子、镁离子结合,阻碍了湿巾消毒液与载体纤维中铁离子、钙离子、镁离子结合,对消毒剂几乎无消耗,使得较低水平的消毒剂和抗吸附剂实现了消毒剂全释放,确保了本发明的湿巾消毒液的消毒效果。本发明解决了现有的消毒湿巾的纤维吸附消毒剂,降低了消毒效果的问题。
Description
技术领域
本发明涉及消毒液技术领域,具体涉及一种湿巾消毒液及其制备方法、消毒湿巾。
背景技术
按照卫生专业标准WS/T512-216《医疗机构环境表面清洁与消毒管理规范》3.7的定义,消毒湿巾是指“以非织造物、织物、无尘纸或其他原料为载体,纯化水为生产用水,适量添加消毒剂等原材料,制成的具有清洁和消毒作用的产品,适用于人体、一般物体表面、医疗器械表面和其他物体表面”,又称“载体消毒剂”。消毒湿巾具有携带方便,能及时清洁消毒等优点。
目前具有杀菌功能的湿巾主要为消毒湿巾及抗菌湿巾。这两种具有杀菌功能的湿巾都是将一定量具有杀菌功能的消毒液或抗菌液浸润无纺布、无尘纸等非织造物形成的。无纺布、无尘纸等非织造物等是天然纤维或化工纤维构成。这些纤维对消毒剂尤其具有表面活性的消毒剂有很强的吸附性。前述的纤维表面含有比较多的铁、钙及镁离子等。当消毒液或抗菌液浸润无纺布、无尘纸等非织造物时,其中有抗菌功能的消毒剂会和纤维表面的铁、钙及镁离子等结合后沉积在纤维表面,从而导致消毒剂被无纺布、无尘纸等非织造物等吸附,经检测吸附量有的会达到50%以上。当消毒湿巾及抗菌湿巾中的部分消毒剂被载体吸附,其杀菌功能会大大下降。因此,很多研发人员研制配方时会将消毒剂的用量提高以抵消被载体吸附的消毒剂的量,这样不仅增加了产品成本,也会导致消毒湿巾及抗菌湿巾的腐蚀性及刺激性增加。
发明内容
为克服现有技术所存在的缺陷,现提供一种湿巾消毒液及其制备方法,以解决现有的消毒湿巾的纤维吸附消毒剂,降低了消毒效果的问题。
为实现上述目的,提供一种湿巾消毒液,包括:
以湿巾消毒液的质量为百分百计,湿巾消毒液包括0.05%~1.0%的消毒剂、0.1%~1.0%的表面活性剂、0.1%~0.8%的增效剂、0.15%~0.55%的抗吸附剂、0.1%~0.5%酸碱调节剂及余量的纯化水;
所述消毒剂为苯扎氯铵、苯扎溴铵、聚六亚甲基双胍、聚六亚甲基单胍、葡萄糖酸氯己定、醋酸氯己定,盐酸氯己定、西曲溴铵、双癸基二甲基氯化铵、双辛基二甲基溴化铵、十二烷基三甲基溴化铵、十二烷基三甲基氯化铵,双辛基二甲基氯化铵,双癸基二甲基溴化铵中的至少一种;
所述表面活性剂为椰油酰胺丙基甜菜碱、烷基葡萄糖苷、聚甘油辛酸癸酸甘油酯、聚甘油癸酸酯、吐温-20、PEG-40氢化蓖麻油、脂肪醇聚氧乙烯醚中的至少一种;
所述增效剂为苯氧乙醇、尼泊金甲酯、尼泊金乙酯、尼泊金丙酯、乙基己基甘油、氯苯甘醚、对羟基苯乙酮、辛甘醇、戊二醇、三氯羟基二苯醚、甲基异噻唑啉酮中的至少一种;
所述抗吸附剂为磷酸钠、磷酸氢二钠、磷酸二氢钠、多聚磷酸钠、氮川三乙酸三钠、甲基甘氨酸二乙酸三钠、氨基三甲叉磷酸,羟基乙叉二磷酸、乙二胺四甲叉膦酸、乙二胺四甲叉磷酸、二乙烯三胺五亚甲基膦酸、多元醇磷酸酯、乙二胺四乙酸二钠、乙二胺四乙酸四钠中的至少一种;
所述湿巾消毒液的PH值为4.0~8.5。
进一步的,所述酸碱调节剂为氢氧化钠、氢氧化钾、柠檬酸、柠檬酸钠、苹果酸、乳酸、琥珀酸。
进一步的,以湿巾消毒液的质量为百分百计,所述湿巾消毒液包括0.5%的葡萄糖酸氯己定、0.2%的聚甘油癸酸酯、0.1%的乙基己基甘油、0.1%的磷酸二氢钠、0.1%的柠檬酸钠和余量的纯化水。
进一步的,以湿巾消毒液的质量为百分百计,所述湿巾消毒液包括0.5%的苯扎溴铵、0.2%的吐温-20、0.1%的氯苯甘醚、0.25%的氮川三乙酸三钠、0.5%的柠檬酸和余量的纯化水。
进一步的,以湿巾消毒液的质量为百分百计,所述湿巾消毒液包括4%的苯扎氯铵、0.2%的烷基葡萄糖苷、0.1%的氯苯甘醚、0.35%的氨基三甲叉磷酸、0.6%的氢氧化钠和余量的纯化水。
本发明提供一种湿巾消毒液制备方法,包括以下步骤:
将0.15%~0.55%的抗吸附剂溶解于部分纯化水中配置形成基础料液;
将0.1%~1.0%的表面活性剂和0.1%~0.8%的增效剂加入所述基础料液中混合均匀以配置形成混合料液;
将0.1%~0.5%酸碱调节剂加入所述混合料液中混合均匀以配置形成调和料液,使得所述调和料液的PH值为4.0~8.5;
将0.05%~1.0%的消毒剂和余量的纯化水加入所述调和料液中混合均匀制得湿巾消毒液。
本发明提供一种消毒湿巾,包括:
湿巾本体;
如权利要求1~5中任意一项所述的湿巾消毒液,所述湿巾消毒液浸润所述湿巾本体,所述湿巾消毒液的重量为所述湿巾本体的重量的3~6倍。
本发明的有益效果在于,本发明的湿巾消毒液在浸润无纺布或无尘纸等湿巾本体或载体,湿巾消毒液的添加量为湿巾本体或载体重量的3倍~6倍,湿巾本体或载体对本发明的湿巾消毒液中消毒剂几乎无吸附,其中,抗吸附剂以优异的铁离子、钙离子、镁离子等屏蔽能力,在抗吸附剂与湿巾本体或载体的纤维中铁离子、钙离子、镁离子结合,阻碍了湿巾消毒液与载体纤维中铁离子、钙离子、镁离子结合,对消毒剂几乎无消耗,使得较低水平的消毒剂和抗吸附剂实现了消毒剂全释放,确保了本发明的湿巾消毒液的消毒效果。
具体实施方式
下面结合实施例对本申请作进一步的详细说明。可以理解的是,此处所描述的具体实施例仅仅用于解释相关发明,而非对该发明的限定。
需要说明的是,在不冲突的情况下,本申请中的实施例及实施例中的特征可以相互组合。下面将结合实施例来详细说明本申请。
本发明提供了一种湿巾消毒液,以湿巾消毒液的质量为百分百计,湿巾消毒液包括0.05%~1.0%的消毒剂、0.1%~1.0%的表面活性剂、0.1%~0.8%的增效剂、0.15%~0.55%的抗吸附剂、0.1%~0.5%酸碱调节剂及余量的纯化水。
消毒剂为苯扎氯铵、苯扎溴铵、聚六亚甲基双胍、聚六亚甲基单胍、葡萄糖酸氯己定、醋酸氯己定,盐酸氯己定、西曲溴铵、双癸基二甲基氯化铵、双辛基二甲基溴化铵、十二烷基三甲基溴化铵、十二烷基三甲基氯化铵,双辛基二甲基氯化铵,双癸基二甲基溴化铵中的至少一种。
表面活性剂为椰油酰胺丙基甜菜碱、烷基葡萄糖苷、聚甘油辛酸癸酸甘油酯、聚甘油癸酸酯、吐温-20、PEG(聚乙烯)-40氢化蓖麻油、脂肪醇聚氧乙烯醚中的至少一种。
在本实施例中,表面活性剂用于降低表面张力,使得消毒液易于浸润无纺布或无尘纸等载体(即湿巾本体)。
增效剂为苯氧乙醇、尼泊金甲酯、尼泊金乙酯、尼泊金丙酯、乙基己基甘油、氯苯甘醚、对羟基苯乙酮、辛甘醇、戊二醇、三氯羟基二苯醚、甲基异噻唑啉酮中的至少一种。
在本实施例中,杀菌增效剂用于提升消毒剂的杀菌效果,提供广谱抑菌。
抗吸附剂为磷酸钠、磷酸氢二钠、磷酸二氢钠、多聚磷酸钠、氮川三乙酸三钠、甲基甘氨酸二乙酸三钠、氨基三甲叉磷酸,羟基乙叉二磷酸、乙二胺四甲叉膦酸、乙二胺四甲叉磷酸、二乙烯三胺五亚甲基膦酸、多元醇磷酸酯、乙二胺四乙酸二钠、乙二胺四乙酸四钠中的至少一种。
在本实施例中,抗吸附剂具有优异的屏蔽铁离子、钙离子、镁离子能力,抗吸附剂与湿巾本体或载体的纤维中铁离子、钙离子、镁离子结合,阻碍了湿巾消毒液与载体纤维中铁离子、钙离子、镁离子结合,起到抗吸附作用。
在本实施例中,湿巾消毒液的PH值为4.0~8.5。具体的,通过酸碱调节剂的作用将湿巾消毒液的酸碱度调节在4.0-8.5之间。
其中,酸碱调节剂为氢氧化钠、氢氧化钾、柠檬酸、柠檬酸钠、苹果酸、乳酸、琥珀酸。
作为一种较佳的实施方式,以湿巾消毒液的质量为百分百计,湿巾消毒液包括0.5%的葡萄糖酸氯己定、0.2%的聚甘油癸酸酯、0.1%的乙基己基甘油、0.1%的磷酸二氢钠、0.1%的柠檬酸钠和余量的纯化水。
作为一种较佳的实施方式,以湿巾消毒液的质量为百分百计,湿巾消毒液包括0.5%的苯扎溴铵、0.2%的吐温-20、0.1%的氯苯甘醚、0.25%的氮川三乙酸三钠、0.5%的柠檬酸和余量的纯化水。
作为一种较佳的实施方式,以湿巾消毒液的质量为百分百计,湿巾消毒液包括4%的苯扎氯铵、0.2%的烷基葡萄糖苷、0.1%的氯苯甘醚、0.35%的氨基三甲叉磷酸、0.6%的氢氧化钠和余量的纯化水。
本发明的湿巾消毒液在浸润无纺布或无尘纸等湿巾本体或载体,湿巾消毒液的添加量为湿巾本体或载体重量的3倍~6倍,湿巾本体或载体对本发明的湿巾消毒液中消毒剂几乎无吸附,其中,抗吸附剂以优异的铁离子、钙离子、镁离子等屏蔽能力,在抗吸附剂与湿巾本体或载体的纤维中铁离子、钙离子、镁离子结合,阻碍了湿巾消毒液与载体纤维中铁离子、钙离子、镁离子结合,对消毒剂几乎无消耗,使得较低水平的消毒剂和抗吸附剂实现了消毒剂全释放,确保了本发明的湿巾消毒液的消毒效果。
本发明提供一种湿巾消毒液制备方法,包括以下步骤:
S1、将0.15%~0.55%的抗吸附剂溶解于部分纯化水中配置形成基础料液。
S2、将0.1%~1.0%的表面活性剂和0.1%~0.8%的增效剂加入基础料液中混合均匀以配置形成混合料液。
S3、将0.1%~0.5%酸碱调节剂加入混合料液中混合均匀以配置形成调和料液,使得调和料液的PH值为4.0~8.5。
S4、将0.05%~1.0%的消毒剂和余量的纯化水加入调和料液中混合均匀制得湿巾消毒液。
本发明提供一种消毒湿巾,包括湿巾本体和前述的湿巾消毒液。具体的,湿巾消毒液用于浸润湿巾本体。其中,湿巾消毒液的重量为湿巾本体的重量的3~6倍。
本发明的湿巾消毒液制备方法在在常温(10~25℃)和常压(约1个大气压)的条件下进行。
在制备湿巾消毒液时,先在配料桶中加入所需60%左右量的纯化水,将抗吸附剂加入配料桶中搅拌10分钟,直至完全溶解。将表面活性剂、杀菌增效剂依次加入上述溶液中,搅拌10分钟直至完全混合均匀。将酸碱调节剂依次加入上述溶液中,搅拌10分钟直至混合均匀。将消毒剂及剩余40%纯化水加入上述溶液中,搅拌10-15分钟,直至混合均匀,静置30分钟,得到一澄清透明的湿巾消毒液,溶液PH值4.0-8.5之间。
在制备消毒湿巾时,将湿巾消毒液浸润无纺布或无尘纸等湿巾本体或载体上,湿巾消毒液的加液量为湿巾本体或载体的重量的3倍~6倍。湿巾本体或载体对湿巾消毒液中消毒剂几乎无吸附。
为了具体说明书湿巾消毒液用于湿巾的技术效果,特举以下实施例和对比例以示说明。
实施例1
将5.5克磷酸二氢钠(抗吸附剂)加入600g水中,搅拌10分钟使之完全溶解;依次加入2.0克聚甘油癸酸酯(表面活性剂)、1.0克乙基己基甘油(增效剂)加入到上述溶液中,搅拌10分钟使之完全溶解,将1克柠檬酸钠(酸碱调节剂)依次到上述溶液中,搅拌10分钟使之完全溶解;最后加入5.0克葡萄糖酸氯己定(消毒剂),将所得的混合物用水加到1000g,并搅拌30分钟使之完全混合均匀,调节PH值为5.0~6.0之间,得到澄清透明消毒液。按照湿巾消毒液与无纺布质量比4:1将消毒液加入到无纺布中并进行包装形成湿巾。
实施例2
将2.5氮川三乙酸三钠(抗吸附剂)加入600g水中,搅拌10分钟使之完全溶解;依次加入2.0克吐温-20(表面活性剂)、1.0克氯苯甘醚(增效剂)加入到上述溶液中,搅拌10分钟使之完全溶解,将5克柠檬酸(酸碱调节剂)依次到上述溶液中,搅拌10分钟使之完全溶解;最后加入5.0克苯扎溴铵(消毒剂),将所得的混合物用水加到1000g,并搅拌30分钟使之完全混合均匀,调节PH值为5.0~6.0之间,得到澄清透明消毒液。按照湿巾消毒液与无纺布质量比4:1将消毒液加入到无纺布中并进行包装形成湿巾。
实施例3
将3.5克氨基三甲叉磷酸(抗吸附剂)加入600g水中,搅拌10分钟使之完全溶解;依次加入2.0克烷基葡萄糖苷(表面活性剂)、1.0克氯苯甘醚(增效剂)加入到上述溶液中,搅拌10分钟使之完全溶解,将6.0克氢氧化钠(酸碱调节剂)依次到上述溶液中,搅拌10分钟使之完全溶解;最后加入4.0克苯扎氯铵(消毒剂),将所得的混合物用水加到1000g,并搅拌30分钟使之完全混合均匀,调节PH值为6.0~7.0之间,得到澄清透明消毒液。按照湿巾消毒液与无纺布质量比4:1将消毒液加入到无尘纸中并进行包装形成湿巾。
对比例1
将2.0克聚甘油癸酸酯、1.0克乙基己基甘油加入到600克纯化水中,搅拌10分钟使之完全溶解,将1.0柠檬酸钠依次到上述溶液中,搅拌10分钟使之完全溶解;最后加入5.0克葡萄糖酸氯己定,将所得的混合物用水加到1000g,并搅拌30分钟使之完全混合均匀,调节PH值为5.0~6.0之间,得到澄清透明消毒液。按照消毒液与无纺布质量比4:1将消毒液加入到无纺布中并进行包装形成湿巾。
对比例2
将2.0克烷基糖苷、1.0克氯苯甘醚加入600克纯化水中,搅拌10分钟使之完全溶解,将1.0柠檬酸钠依次到上述溶液中,搅拌10分钟使之完全溶解;最后加入4.0克苯扎氯铵,将所得的混合物用水加到1000g,并搅拌30分钟使之完全混合均匀,调节PH值为6.0~7.0之间,得到澄清透明消毒液。按照消毒液与无纺布质量比4:1将消毒液加入到无尘纸中并进行包装形成湿巾。
对比例3
将0.9克磷酸二氢钠加入600g水中,搅拌10分钟使之完全溶解;依次加入2.0克聚甘油癸酸酯、1.0克乙基己基甘油加入到上述溶液中,搅拌10分钟使之完全溶解,将1.0柠檬酸钠依次到上述溶液中,搅拌10分钟使之完全溶解;最后加入5.0克葡萄糖酸氯己定,将所得的混合物用水加到1000g,并搅拌30分钟使之完全混合均匀,调节PH值为5.0~6.0之间,得到澄清透明消毒液。按照消毒液与无纺布质量比4:1将消毒液加入到无纺布中并进行包装形成湿巾。
对比例4
将1.2克氨基三甲叉磷酸加入600g水中,搅拌10分钟使之完全溶解;依次加入2.0克烷基糖苷、1.0克氯苯甘醚加入到上述溶液中,搅拌10分钟使之完全溶解,将0.6氢氧化钠依次到上述溶液中,搅拌10分钟使之完全溶解;最后加入4.0克苯扎氯铵,将所得的混合物用水加到1000g,并搅拌30分钟使之完全混合均匀,调节PH值为6.0~7.0之间,得到澄清透明消毒液。按照消毒液与无纺布质量比4:1将消毒液加入到无尘纸中并进行包装形成湿巾。
消毒效果实验,参照2002年版《消毒技术规范》中2.1.1.7实验方法进行大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌、白色念珠菌的杀菌测试。
消毒剂含量测定,参照2002年版《消毒技术规范》中2.2.1实验方法进行消毒剂含量测试。
实施列及对比例的消毒效果及消毒剂含量测试结果如下表表2:
表2、消毒效果及消毒剂含量测试结果
测试项目 | 白色念珠菌杀菌率 | 消毒剂含量 |
实施例1(未浸润载体的消毒液) | 杀菌率≥99.99% | 葡萄糖酸氯己定4.95g/L |
实施例1(湿巾挤出液) | 杀菌率≥99.99% | 葡萄糖酸氯己定4.93g/L |
实施例2(未浸润载体的消毒液) | 杀菌率≥99.99% | 苯扎溴铵5.05g/L |
实施例2(湿巾挤出液) | 杀菌率≥99.99% | 苯扎溴铵5.05g/L |
实施例3(未浸润载体的消毒液) | 杀菌率≥99.99% | 苯扎氯铵4.12g/L |
实施例3(湿巾挤出液) | 杀菌率≥99.99% | 苯扎氯铵4.08g/L |
对比例1(未浸润载体的消毒液) | 杀菌率≥99.99% | 葡萄糖酸氯己定5.01g/L |
对比例1(湿巾挤出液) | 杀菌率≥98.5% | 葡萄糖酸氯己定3.31g/L |
对比例2(未浸润载体的消毒液) | 杀菌率≥99.99% | 苯扎氯铵4.23g/L |
对比例2(湿巾挤出液) | 杀菌率≥99.1% | 苯扎氯铵2.86g/L |
对比例3(未浸润载体的消毒液) | 杀菌率≥99.99% | 葡萄糖酸氯己定4.95g/L |
对比例3(湿巾挤出液) | 杀菌率≥99.7% | 葡萄糖酸氯己定3.66g/L |
对比例4(未浸润载体的消毒液) | 杀菌率≥99.99% | 苯扎氯铵4.15g/L |
对比例4(湿巾挤出液) | 杀菌率≥99.9% | 苯扎氯铵3.74g/L |
从上面表中实施例、对比例的消毒效果及消毒剂含量可以看出,各实施例中的湿巾消毒液中含一定量的抗吸附剂,未浸润载体的湿巾消毒液及湿巾挤出液中消毒剂的含量几乎一样,说明抗吸附剂阻碍了湿巾载体对消毒剂的吸附,未浸润载体的湿巾消毒液及湿巾挤出液对白色念珠菌的杀菌效果几乎是一样的。
而对比例1~2中未浸润载体的消毒液对白色念珠菌的杀菌效果符合要求,因消毒液中未加抗吸附剂湿巾挤出液中消毒剂被湿巾载体吸附,湿巾挤出液中消毒剂含量仅为未浸润载体的消毒液65%左右,35%左右的消毒剂被湿巾载体吸附,导致湿巾挤出液对白色念珠菌的杀菌效率大大降低,达不到标准要求。
对比例3中抗吸附剂含量为0.09%,湿巾挤出液中消毒剂含量为未浸润载体的消毒液74%左右,26%左右的消毒剂被湿巾载体吸附,对比例4中抗吸附剂含量为0.12%,湿巾挤出液中消毒剂含量为未浸润载体的消毒液90%左右,10%左右的消毒剂被湿巾载体吸附,可以看出随着抗吸附剂用量增加,消毒剂被湿巾载体吸附的量在减少,杀菌效果在增强,当抗吸附剂含量为0.15%及以上时,湿巾挤出液中消毒剂就不再被湿巾载体吸附了,未浸润载体的湿巾消毒液及湿巾挤出液的杀菌效果几乎一样了。
以上描述仅为本申请的较佳实施例以及对所运用技术原理的说明。本领域技术人员应当理解,本申请中所涉及的发明范围,并不限于上述技术特征的特定组合而成的技术方案,同时也应涵盖在不脱离所述发明构思的情况下,由上述技术特征或其等同特征进行任意组合而形成的其它技术方案。例如上述特征与本申请中公开的(但不限于)具有类似功能的技术特征进行互相替换而形成的技术方案。
Claims (7)
1.一种湿巾消毒液,其特征在于,以湿巾消毒液的质量为百分百计,湿巾消毒液包括0.05%~1.0%的消毒剂、0.1%~1.0%的表面活性剂、0.1%~0.8%的增效剂、0.15%~0.55%的抗吸附剂、0.1%~0.5%酸碱调节剂及余量的纯化水;
所述消毒剂为苯扎氯铵、苯扎溴铵、聚六亚甲基双胍、聚六亚甲基单胍、葡萄糖酸氯己定、醋酸氯己定,盐酸氯己定、西曲溴铵、双癸基二甲基氯化铵、双辛基二甲基溴化铵、十二烷基三甲基溴化铵、十二烷基三甲基氯化铵,双辛基二甲基氯化铵,双癸基二甲基溴化铵中的至少一种;
所述表面活性剂为椰油酰胺丙基甜菜碱、烷基葡萄糖苷、聚甘油辛酸癸酸甘油酯、聚甘油癸酸酯、吐温-20、PEG-40氢化蓖麻油、脂肪醇聚氧乙烯醚中的至少一种;
所述增效剂为苯氧乙醇、尼泊金甲酯、尼泊金乙酯、尼泊金丙酯、乙基己基甘油、氯苯甘醚、对羟基苯乙酮、辛甘醇、戊二醇、三氯羟基二苯醚、甲基异噻唑啉酮中的至少一种;
所述抗吸附剂为磷酸钠、磷酸氢二钠、磷酸二氢钠、多聚磷酸钠、氮川三乙酸三钠、甲基甘氨酸二乙酸三钠、氨基三甲叉磷酸,羟基乙叉二磷酸、乙二胺四甲叉膦酸、乙二胺四甲叉磷酸、二乙烯三胺五亚甲基膦酸、多元醇磷酸酯、乙二胺四乙酸二钠、乙二胺四乙酸四钠中的至少一种;
所述湿巾消毒液的PH值为4.0~8.5。
2.根据权利要求1所述的湿巾消毒液,其特征在于,所述酸碱调节剂为氢氧化钠、氢氧化钾、柠檬酸、柠檬酸钠、苹果酸、乳酸、琥珀酸。
3.根据权利要求2所述的湿巾消毒液,其特征在于,以湿巾消毒液的质量为百分百计,所述湿巾消毒液包括0.5%的葡萄糖酸氯己定、0.2%的聚甘油癸酸酯、0.1%的乙基己基甘油、0.1%的磷酸二氢钠、0.1%的柠檬酸钠和余量的纯化水。
4.根据权利要求2所述的湿巾消毒液,其特征在于,以湿巾消毒液的质量为百分百计,所述湿巾消毒液包括0.5%的苯扎溴铵、0.2%的吐温-20、0.1%的氯苯甘醚、0.25%的氮川三乙酸三钠、0.5%的柠檬酸和余量的纯化水。
5.根据权利要求2所述的湿巾消毒液,其特征在于,以湿巾消毒液的质量为百分百计,所述湿巾消毒液包括4%的苯扎氯铵、0.2%的烷基葡萄糖苷、0.1%的氯苯甘醚、0.35%的氨基三甲叉磷酸、0.6%的氢氧化钠和余量的纯化水。
6.一种如权利要求1~5中任意一项所述的湿巾消毒液制备方法,其特征在于,包括以下步骤:
将0.15%~0.55%的抗吸附剂溶解于部分纯化水中配置形成基础料液;
将0.1%~1.0%的表面活性剂和0.1%~0.8%的增效剂加入所述基础料液中混合均匀以配置形成混合料液;
将0.1%~0.5%酸碱调节剂加入所述混合料液中混合均匀以配置形成调和料液,使得所述调和料液的PH值为4.0~8.5;
将0.05%~1.0%的消毒剂和余量的纯化水加入所述调和料液中混合均匀制得湿巾消毒液。
7.一种消毒湿巾,其特征在于,包括:
湿巾本体;
如权利要求1~5中任意一项所述的湿巾消毒液,所述湿巾消毒液浸润所述湿巾本体,所述湿巾消毒液的重量为所述湿巾本体的重量的3~6倍。
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