CN116829187A - 纤维化进展的抑制剂 - Google Patents

纤维化进展的抑制剂 Download PDF

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Publication number
CN116829187A
CN116829187A CN202180091901.4A CN202180091901A CN116829187A CN 116829187 A CN116829187 A CN 116829187A CN 202180091901 A CN202180091901 A CN 202180091901A CN 116829187 A CN116829187 A CN 116829187A
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CN
China
Prior art keywords
ser
thr
fibrosis
seq
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180091901.4A
Other languages
English (en)
Chinese (zh)
Inventor
吉崎步
久住蓝
佐藤伸一
藤田智之
渡部英基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maruho Co Ltd
University of Tokyo NUC
Original Assignee
Maruho Co Ltd
University of Tokyo NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruho Co Ltd, University of Tokyo NUC filed Critical Maruho Co Ltd
Publication of CN116829187A publication Critical patent/CN116829187A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN202180091901.4A 2020-11-30 2021-11-29 纤维化进展的抑制剂 Pending CN116829187A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPPCT/JP2020/044406 2020-11-30
PCT/JP2020/044406 WO2022113316A1 (ja) 2020-11-30 2020-11-30 線維化の進行抑制剤
PCT/JP2021/043543 WO2022114165A1 (ja) 2020-11-30 2021-11-29 線維化の進行抑制剤

Publications (1)

Publication Number Publication Date
CN116829187A true CN116829187A (zh) 2023-09-29

Family

ID=81754505

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180091901.4A Pending CN116829187A (zh) 2020-11-30 2021-11-29 纤维化进展的抑制剂

Country Status (12)

Country Link
US (1) US20240084020A1 (https=)
EP (1) EP4252771A4 (https=)
JP (3) JPWO2022113316A1 (https=)
KR (1) KR20230114698A (https=)
CN (1) CN116829187A (https=)
AU (1) AU2021385871A1 (https=)
CA (1) CA3199351A1 (https=)
CL (1) CL2023001460A1 (https=)
IL (1) IL303159A (https=)
MX (1) MX2023006164A (https=)
TW (1) TW202237182A (https=)
WO (2) WO2022113316A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5954916B1 (ja) 2015-04-14 2016-07-20 中外製薬株式会社 Il−31アンタゴニストを有効成分として含有する、アトピー性皮膚炎の予防用及び/又は治療用医薬組成物
MX2022005654A (es) 2019-11-20 2022-06-22 Chugai Pharmaceutical Co Ltd Preparacion que contiene anticuerpo.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5954916B1 (ja) * 2015-04-14 2016-07-20 中外製薬株式会社 Il−31アンタゴニストを有効成分として含有する、アトピー性皮膚炎の予防用及び/又は治療用医薬組成物

Also Published As

Publication number Publication date
KR20230114698A (ko) 2023-08-01
EP4252771A4 (en) 2024-10-23
JP2022095913A (ja) 2022-06-28
CA3199351A1 (en) 2022-06-02
TW202237182A (zh) 2022-10-01
MX2023006164A (es) 2023-07-28
WO2022114165A1 (ja) 2022-06-02
IL303159A (en) 2023-07-01
JPWO2022114165A1 (https=) 2022-06-02
WO2022113316A1 (ja) 2022-06-02
US20240084020A1 (en) 2024-03-14
AU2021385871A9 (en) 2024-05-02
JP7802601B2 (ja) 2026-01-20
AU2021385871A1 (en) 2023-06-22
CL2023001460A1 (es) 2023-12-01
JPWO2022113316A1 (https=) 2022-06-02
EP4252771A1 (en) 2023-10-04

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