CN116724022A - 肽的制造方法、保护基形成用试药及缩合多环化合物 - Google Patents

肽的制造方法、保护基形成用试药及缩合多环化合物 Download PDF

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Publication number
CN116724022A
CN116724022A CN202180086749.0A CN202180086749A CN116724022A CN 116724022 A CN116724022 A CN 116724022A CN 202180086749 A CN202180086749 A CN 202180086749A CN 116724022 A CN116724022 A CN 116724022A
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CN
China
Prior art keywords
group
peptide
hydrogen atom
formula
protected
Prior art date
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Pending
Application number
CN202180086749.0A
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English (en)
Chinese (zh)
Inventor
津山博昭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Corp
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Publication of CN116724022A publication Critical patent/CN116724022A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/88—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/062—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha- or omega-carboxy functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/066—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amido functions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN202180086749.0A 2020-12-22 2021-12-21 肽的制造方法、保护基形成用试药及缩合多环化合物 Pending CN116724022A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-212819 2020-12-22
JP2020212819 2020-12-22
PCT/JP2021/047183 WO2022138605A1 (ja) 2020-12-22 2021-12-21 ペプチドの製造方法、保護基形成用試薬、及び、縮合多環化合物

Publications (1)

Publication Number Publication Date
CN116724022A true CN116724022A (zh) 2023-09-08

Family

ID=82159395

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180086749.0A Pending CN116724022A (zh) 2020-12-22 2021-12-21 肽的制造方法、保护基形成用试药及缩合多环化合物

Country Status (6)

Country Link
US (1) US20230357311A1 (https=)
EP (1) EP4269423A4 (https=)
JP (1) JPWO2022138605A1 (https=)
CN (1) CN116724022A (https=)
TW (1) TW202233574A (https=)
WO (1) WO2022138605A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025063265A1 (ja) * 2023-09-20 2025-03-27 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、およびジナフチルメチル化合物
JP2025110921A (ja) * 2024-01-17 2025-07-30 富士フイルム株式会社 ペプチドの製造方法、化合物、及びペプチド合成試薬

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2513395B2 (ja) * 1992-11-09 1996-07-03 株式会社島津製作所 ペプチドアミド合成用リンカ―
WO2010113939A1 (ja) 2009-03-30 2010-10-07 味の素株式会社 ジフェニルメタン化合物
US8802819B2 (en) * 2010-10-29 2014-08-12 Lonza Ltd. Diketopiperazine forming dipeptidyl linker
WO2012165546A1 (ja) * 2011-05-31 2012-12-06 味の素株式会社 ペプチドの製造方法
JP6283775B1 (ja) 2016-07-25 2018-02-21 積水メディカル株式会社 新規キサンテン保護剤
JP7023120B2 (ja) 2018-01-12 2022-02-21 オリンパス株式会社 内視鏡装置、内視鏡装置の作動方法およびプログラム
CN110317188B (zh) * 2018-03-29 2023-01-17 深圳翰宇药业股份有限公司 化合物及其制备方法和应用
CN113508103A (zh) 2019-02-28 2021-10-15 富士胶片株式会社 肽化合物的制造方法、保护基形成用试药及稠合多环芳香族烃化合物
JP7628073B2 (ja) 2019-02-28 2025-02-07 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、芳香族複素環化合物
JP7301965B2 (ja) * 2019-06-28 2023-07-03 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、縮合多環化合物

Also Published As

Publication number Publication date
EP4269423A4 (en) 2024-08-07
TW202233574A (zh) 2022-09-01
US20230357311A1 (en) 2023-11-09
EP4269423A1 (en) 2023-11-01
JPWO2022138605A1 (https=) 2022-06-30
WO2022138605A1 (ja) 2022-06-30

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