CN116656676A - 一对用于编辑人pcsk9核酸序列的辅助引导rna/引导rna - Google Patents

一对用于编辑人pcsk9核酸序列的辅助引导rna/引导rna Download PDF

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CN116656676A
CN116656676A CN202211043562.5A CN202211043562A CN116656676A CN 116656676 A CN116656676 A CN 116656676A CN 202211043562 A CN202211043562 A CN 202211043562A CN 116656676 A CN116656676 A CN 116656676A
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editing
site
seq
guide rnas
base
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陈佳
杨贝
杨力
黄行许
王丽洁
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ShanghaiTech University
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ShanghaiTech University
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    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
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    • C12Y305/04004—Adenosine deaminase (3.5.4.4)
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CN202211043562.5A 2019-02-02 2020-02-03 一对用于编辑人pcsk9核酸序列的辅助引导rna/引导rna Pending CN116656676A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN2019074577 2019-02-02
CNPCT/CN2019/074577 2019-02-02
CN202080026986.3A CN113661248B (zh) 2019-02-02 2020-02-03 基因编辑中非预期突变的抑制
PCT/CN2020/074218 WO2020156575A1 (en) 2019-02-02 2020-02-03 Inhibition of unintended mutations in gene editing

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CN202211043562.5A Pending CN116656676A (zh) 2019-02-02 2020-02-03 一对用于编辑人pcsk9核酸序列的辅助引导rna/引导rna
CN202211057011.4A Pending CN116355966A (zh) 2019-02-02 2020-02-03 一种融合蛋白在遗传编辑的用途
CN202080026986.3A Active CN113661248B (zh) 2019-02-02 2020-02-03 基因编辑中非预期突变的抑制
CN202211042699.9A Pending CN116286802A (zh) 2019-02-02 2020-02-03 一种包含支架的引导rna及利用其的遗传编辑的方法

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CN202211057011.4A Pending CN116355966A (zh) 2019-02-02 2020-02-03 一种融合蛋白在遗传编辑的用途
CN202080026986.3A Active CN113661248B (zh) 2019-02-02 2020-02-03 基因编辑中非预期突变的抑制
CN202211042699.9A Pending CN116286802A (zh) 2019-02-02 2020-02-03 一种包含支架的引导rna及利用其的遗传编辑的方法

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EP (1) EP3918083A4 (https=)
JP (3) JP7518549B2 (https=)
KR (1) KR20210126042A (https=)
CN (4) CN116656676A (https=)
AU (3) AU2020214090B2 (https=)
BR (1) BR112021015092A2 (https=)
CA (1) CA3128283A1 (https=)
IL (1) IL285194A (https=)
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